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Journal Articles

Tocilizumab Administration in CAR-T Cell Associated Cytokine Release Syndrome Induces Hypofibrinogenemia

Markus Perl, Konstantin Herfeld, Dennis Harrer, Matthias Hoepting, Marina Schweiger, Ulrich Sterz, Leonard Knoedler, Leo Hansmann, Wolfgang Herr, Hendrik Poeck, Daniel Wolff, Matthias Edinger, Christina Hart, Matthias Fante

Blood (2023) 142 (Supplement 1): 5493.

https://doi.org/10.1182/blood-2023-186878

Published: 2023

Journal Articles

Bacterial and Bacteriophage Consortia Are Associated with Protective Intestinal Immuno-Modulatory Metabolites in Allogeneic Stem Cell Transplantation Patients

Blood (2023) 142 (Supplement 1): 477.

https://doi.org/10.1182/blood-2023-172457

Published: 2023

Journal Articles

Effects of Bacterial Metabolites on CAR-T Cell Therapy

Luisa Becker, Markus Perl, Leonard Knödler, Wolfgang Herr, Hendrik Poeck

Blood (2022) 140 (Supplement 1): 12703.

https://doi.org/10.1182/blood-2022-169496

Published: 2022

Journal Articles

Results of the Risk-Adapted, MRD-Stratified GMALL Trial 08/2013 in 281 T-ALL / T-Lbl Patients: Excellent Outcome of Standard Risk Thymic T-ALL

Blood (2022) 140 (Supplement 1): 115–117.

https://doi.org/10.1182/blood-2022-158381

Published: 2022

Journal Articles

Overcoming CAR-T Cell Exhaustion and Improving Antitumoral Efficacy in Hematologic Neoplasms Utilizing CRISPR/Cas9 Technology

Leonard Knoedler, Markus Perl, Luisa Becker, Hendrik Poeck, Christian Schmidl, Wolfgang Herr

Blood (2022) 140 (Supplement 1): 12701–12702.

https://doi.org/10.1182/blood-2022-167369

Published: 2022

Journal Articles

Immunomodulatory Microbial Metabolites Identified in Allo-SCT Patients Protect from GvHD By Sting Dependent Modulation of Intestinal Tissue Homeostasis

Sascha Göttert, Erik Thiele-Orberg, Kaiji Fan, Sakhila Ghimire, Paul Heinrich, Wolfgang Herr, Simon Heidegger, Ernst Holler, Hendrik Poeck

Blood (2022) 140 (Supplement 1): 7336–7337.

https://doi.org/10.1182/blood-2022-169118

Published: 2022

Journal Articles

IFN-Gamma Is Crucial for the Counterbalance of T Cell-Mediated Injury to the Intestinal Stem Cell Compartment By Regulatory T Cells in Mice and Humans

Sascha Göttert, Julius Clemens Fischer, Gabriel Eisenkolb, Erik Thiele Orberg, Sebastian Jarosch, Ernst Holler, Dirk Busch, Simon Heidegger, Hendrik Poeck

Blood (2022) 140 (Supplement 1): 10223–10224.

https://doi.org/10.1182/blood-2022-169303

Published: 2022

Journal Articles

Identification of Bacterial and Viral Consortia for the Production of Intestinal Microbiota-Derived Metabolites Associated with Protection in Allogeneic Stem Cell Transplantation Patients

Blood (2022) 140 (Supplement 1): 7619–7621.

https://doi.org/10.1182/blood-2022-157423

Published: 2022

Journal Articles

IFN-Gamma Producing Regulatory T Cells Counterbalance T Cell-Mediated Injury to the Intestinal Stem Cell Compartment in Mice and Humans

Sascha Göttert, Julius Clemens Fischer, Gabriel Eisenkolb, Erik Thiele Orberg, Dirk Busch, Sebastian Jarosch, Ernst Holler, Thomas Engleitner, Lena Klostermeier, Caroline Walther, Laura Lansink Rotgerink, Sophie Nefzger, Marianne Reiser, Katja Steiger, Roland Rad, Stefanie E. Combs, Florian Bassermann, Simon Heidegger, Hendrik Poeck

Blood (2021) 138 (Supplement 1): 89.

https://doi.org/10.1182/blood-2021-152925

Published: 2021

Journal Articles

Microbial-Derived Metabolites Induce Epithelial Recovery Via the Sting Pathway in Mice and Men and Protect from Graft-Versus-Host Disease

Erik Thiele Orberg, Sascha Göttert, Andreas Hiergeist, Elisabeth Meedt, Karin Kleigrewe, Wolfgang Herr, Florian Bassermann, Andre Gessner, Ernst Holler, Simon Heidegger, Hendrik Poeck

Blood (2021) 138 (Supplement 1): 87.

https://doi.org/10.1182/blood-2021-147794

Published: 2021

Journal Articles

Longitudinal Analysis of Gut Bacteriome, Mycobiome, Virome and Metabolome in Allogeneic Stem Cell Transplantation Reveals Susceptibility for Acute Graft-Versus-Host Disease

Blood (2021) 138 (Supplement 1): 332.

https://doi.org/10.1182/blood-2021-153026

Published: 2021

Journal Articles

RIG-I Activation Is Critical for Responsiveness to Checkpoint Blockade

Simon Heidegger, MD, Alexander Wintges, Florian Stritzke, Katja Steiger, Paul-Albert Koenig, Thomas Engleitner, Julius Clemens Fischer, Vladimir Makarov, Christof Winter, Roland Rad, Marcel R.M. van den Brink, MD PhD, Jürgen Ruland, Florian Bassermann, MD PhD, Timothy Chan, Tobias Haas, MD, Hendrik Poeck, MD

Blood (2019) 134 (Supplement_1): 624.

https://doi.org/10.1182/blood-2019-128724

Published: 2019

Journal Articles

Type I Interferon Signaling before Hematopoietic Stem Cell Transplantation Lowers Donor T Cell Activation Via Reduced Allogenicity of Recipient Cells

Erik Thiele Orberg, MD PhD, Julius Clemens Fischer, Sascha Göttert, Florian Bassermann, MD PhD, Hendrik Poeck, MD

Blood (2019) 134 (Supplement_1): 4431.

https://doi.org/10.1182/blood-2019-128784

Published: 2019

Journal Articles

Microbial-Derived Metabolites Drive Protective Type-I Interferon Responses in Models of Gut Epithelial Damage and Limit Graft-Versus-Host Disease

Erik Thiele Orberg, MD PhD, Sascha Göttert, Hendrik Poeck, MD

Blood (2019) 134 (Supplement_1): 3207.

https://doi.org/10.1182/blood-2019-125850

Published: 2019

Journal Articles

Tumor-Intrinsic RIG-I Signaling Promotes Anti-CTLA-4 Checkpoint Inhibitor-Mediated Anticancer Immunity

Simon Heidegger, MD, Alexander Wintges, Sarah Bek, Martina Schmickl, Jürgen Ruland, MD, Marcel R.M. van den Brink, MD PhD, Christian Peschel, MD, Tobias Haas, MD, Hendrik Poeck, MD

Blood (2017) 130 (Supplement 1): 693.

https://doi.org/10.1182/blood.V130.Suppl_1.693.693

Published: 2017

Journal Articles

The RIG-I Agonist 3pRNA Synergizes with Checkpoint Blockade in Cancer Immunotherapy

Simon Heidegger, MD, Diana Kreppel, Michael Bscheider, MD, Alexander Wintges, Sarah Bek, Martina Schmickl, Jürgen Ruland, MD, Christian Peschel, MD, Marcel van den Brink, MD, Tobias Haas, MD, Hendrik Poeck, MD

Blood (2015) 126 (23): 3436.

https://doi.org/10.1182/blood.V126.23.3436.3436

Published: 2015

Journal Articles

RIG-I-Induced Type I IFNs Promote Regeneration of the Intestinal Stem Cell Compartment during Acute Tissue Damage

Blood (2015) 126 (23): 3072.

https://doi.org/10.1182/blood.V126.23.3072.3072

Published: 2015

Journal Articles

Response to JAK 1/2 Inhibition in Patients with Corticosteroid-Refractory Acute Graft-Versus-Host Disease

Silvia Spoerl, Kristina Maas-Bauer, Mareike Verbeek, Petya Apostolova, Anna Lena Illert, Nimitha Mathew, Hendrik Poeck, Hartmut Bertz, Jürgen Finke, Christian Peschel, Justus Duyster, Robert Zeiser, Nikolas von Bubnoff

Blood (2014) 124 (21): 3934.

https://doi.org/10.1182/blood.V124.21.3934.3934

Published: 2014

Journal Articles

The Role of the Cytoplasmic RNA Sensor Retinoic Acid Inducible Gene- I (RIG-I) in Allogeneic Stem Cell Transplantation

Julius Clemens Fischer, MDcal student, Caroline A Lindemans, MD PhD, Chia-Ching Lin, PhD, Alexander Wintges, graduate student, Michael Bscheider, MD, Tobias Wertheimer, Simon Heidegger, MD, Robert Jenq, MD, Jarrod A Dudakov, PhD, Alan M. Hanash, MD PhD, Christian Peschel, MD, Tobias Haas, MD, Marcel R.M. van den Brink, MD PhD, Hendrik Poeck, MD

Blood (2014) 124 (21): 3827.

https://doi.org/10.1182/blood.V124.21.3827.3827

Published: 2014

Journal Articles

Activity of therapeutic JAK 1/2 blockade in graft-versus-host disease

Silvia Spoerl, Nimitha R. Mathew, Michael Bscheider, Annette Schmitt-Graeff, Sophia Chen, Tony Mueller, Mareike Verbeek, Julius Fischer, Vera Otten, Martina Schmickl, Kristina Maas-Bauer, Jürgen Finke, Christian Peschel, Justus Duyster, Hendrik Poeck, Robert Zeiser, Nikolas von Bubnoff

Blood (2014) 123 (24): 3832–3842.

https://doi.org/10.1182/blood-2013-12-543736

Published: 2014

Includes: Supplemental data

NARROW

Tocilizumab Administration in CAR-T Cell Associated Cytokine Release Syndrome Induces Hypofibrinogenemia

Bacterial and Bacteriophage Consortia Are Associated with Protective Intestinal Immuno-Modulatory Metabolites in Allogeneic Stem Cell Transplantation Patients

Effects of Bacterial Metabolites on CAR-T Cell Therapy

Results of the Risk-Adapted, MRD-Stratified GMALL Trial 08/2013 in 281 T-ALL / T-Lbl Patients: Excellent Outcome of Standard Risk Thymic T-ALL

Overcoming CAR-T Cell Exhaustion and Improving Antitumoral Efficacy in Hematologic Neoplasms Utilizing CRISPR/Cas9 Technology

Immunomodulatory Microbial Metabolites Identified in Allo-SCT Patients Protect from GvHD By Sting Dependent Modulation of Intestinal Tissue Homeostasis

IFN-Gamma Is Crucial for the Counterbalance of T Cell-Mediated Injury to the Intestinal Stem Cell Compartment By Regulatory T Cells in Mice and Humans

Identification of Bacterial and Viral Consortia for the Production of Intestinal Microbiota-Derived Metabolites Associated with Protection in Allogeneic Stem Cell Transplantation Patients

IFN-Gamma Producing Regulatory T Cells Counterbalance T Cell-Mediated Injury to the Intestinal Stem Cell Compartment in Mice and Humans

Microbial-Derived Metabolites Induce Epithelial Recovery Via the Sting Pathway in Mice and Men and Protect from Graft-Versus-Host Disease

Longitudinal Analysis of Gut Bacteriome, Mycobiome, Virome and Metabolome in Allogeneic Stem Cell Transplantation Reveals Susceptibility for Acute Graft-Versus-Host Disease

RIG-I Activation Is Critical for Responsiveness to Checkpoint Blockade

Type I Interferon Signaling before Hematopoietic Stem Cell Transplantation Lowers Donor T Cell Activation Via Reduced Allogenicity of Recipient Cells

Microbial-Derived Metabolites Drive Protective Type-I Interferon Responses in Models of Gut Epithelial Damage and Limit Graft-Versus-Host Disease

Tumor-Intrinsic RIG-I Signaling Promotes Anti-CTLA-4 Checkpoint Inhibitor-Mediated Anticancer Immunity

The RIG-I Agonist 3pRNA Synergizes with Checkpoint Blockade in Cancer Immunotherapy

RIG-I-Induced Type I IFNs Promote Regeneration of the Intestinal Stem Cell Compartment during Acute Tissue Damage

Response to JAK 1/2 Inhibition in Patients with Corticosteroid-Refractory Acute Graft-Versus-Host Disease

The Role of the Cytoplasmic RNA Sensor Retinoic Acid Inducible Gene- I (RIG-I) in Allogeneic Stem Cell Transplantation

Activity of therapeutic JAK 1/2 blockade in graft-versus-host disease

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American Society of Hematology

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American Society of Hematology

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