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Journal Articles

Novel MAGIC composite scores using both clinical symptoms and biomarkers best predict treatment outcomes of acute GVHD

Clinical Trials & Observations
Yu Akahoshi, Nikolaos Spyrou, Daniela Weber, Paibel Aguayo-Hiraldo, Francis Ayuk, Chantiya Chanswangphuwana, Hannah K. Choe, Matthias Eder, Aaron M. Etra, Stephan A. Grupp, Elizabeth O. Hexner, William J. Hogan, Carrie L. Kitko, Sabrina Kraus, Monzr M. Al Malki, Pietro Merli, Muna Qayed, Ran Reshef, Tal Schechter, Evelyn Ullrich, Ingrid Vasova, Matthias Wölfl, Robert Zeiser, Janna Baez, Rahnuma Beheshti, Gilbert Eng, Sigrun Gleich, Nikolaos Katsivelos, Steven Kowalyk, George Morales, Rachel Young, Yi-Bin Chen, Ryotaro Nakamura, John E. Levine, James L. M. Ferrara
Journal: Blood
Blood (2024) 144 (9): 1010–1021.
https://doi.org/10.1182/blood.2024025106
Published: 2024
Includes: Supplemental data
Journal Articles

The Genomic Landscape and Its Clinical Implication in NPM1 -Mutated AML Patients: A Study within the AMLSG 09-09 Clinical Trial

Sibylle Cocciardi, Nina Weiß, Maral Saadati, Sabrina Skambraks, Daniela Weber, Isabelle Schneider, Annika Meid, Sophia Aicher, Kathrin Bengesser-Kuhn, Andrea Corbacioglu, Verena I. Gaidzik, Frauke Theis, Walter Fiedler, Michael Kühn, Ulrich Germing, Karin T. Mayer, Michael Lübbert, Felicitas Thol, Michael Heuser, Arnold Ganser, Lars Bullinger, Axel Benner, Hartmut Döhner, Konstanze Döhner
Journal: Blood
Blood (2023) 142 (Supplement 1): 4311.
https://doi.org/10.1182/blood-2023-185566
Published: 2023
Journal Articles

Flares of Acute Graft-Versus-Host Disease: Mount Sinai Acute Gvhd International Consortium (MAGIC) Study

Yu Akahoshi, Nikolaos Spyrou, Daniela Weber, Paibel Aguayo-Hiraldo, Francis A. Ayuk, Udomsak Bunworasate, Hannah Choe, Matthias Eder, Aaron Etra, Stephan Grupp, Elizabeth O Hexner, William J. Hogan, Carrie L. Kitko, Sabrina Kraus, Pietro Merli, Muna Qayed, Ran Reshef, Tal Schechter-Finkelstein, Evelyn Ullrich, Ingrid Vasova, Matthias Woelfl, Robert Zeiser, Janna Baez, Rahnuma Beheshti, Sigrun Gleich, Nikolaos Katsivelos, Steven Kowalyk, George Morales, Rachel Young, Yi-Bin Chen, James L.M. Ferrara, John Levine, Ryotaro Nakamura
Journal: Blood
Blood (2023) 142 (Supplement 1): 776.
https://doi.org/10.1182/blood-2023-181900
Published: 2023
Journal Articles

Bacterial and Bacteriophage Consortia Are Associated with Protective Intestinal Immuno-Modulatory Metabolites in Allogeneic Stem Cell Transplantation Patients

Erik Thiele Orberg, Elisabeth Meedt, Andreas Hiergeist, Jinling Xue, Paul Heinrich, Sakhila Ghimire, Oriana Miltiadous, Sarah Lindner, Alix Schwarz, Klaus-Peter Janssen, Peter Herhaus, Mareike Verbeek, Marcel R.M. van den Brink, Daniela Weber, Matthias Edinger, Daniel Wolff, Karin Kleigrewe, Wolfgang Herr, Florian Bassermann, André Gessner, Li Deng, Ernst Holler, Hendrik Poeck
Journal: Blood
Blood (2023) 142 (Supplement 1): 477.
https://doi.org/10.1182/blood-2023-172457
Published: 2023
Journal Articles

Identification of Bacterial and Viral Consortia for the Production of Intestinal Microbiota-Derived Metabolites Associated with Protection in Allogeneic Stem Cell Transplantation Patients

Erik Thiele Orberg, Elisabeth Meedt, Andreas Hiergeist, Jinling Xue, Paul Heinrich, Sakhila Ghimire, Melanie Tiefgraber, Sophia Göldel, Tina Eismann, Alix Schwarz, Sebastian Jarosch, Katja Steiger, Karin Kleigrewe, Julius Clemens Fischer, Klaus-Peter Janssen, Michael Quante, Simon Heidegger, Peter Herhaus, Mareike Verbeek, Jürgen Ruland, Christian Schulz, Daniela Weber, Matthias Edinger, Daniel Wolff, Dirk Busch, Wolfgang Herr, Florian Bassermann, Li Deng, Andre Gessner, Ernst Holler, Hendrik Poeck
Journal: Blood
Blood (2022) 140 (Supplement 1): 7619–7621.
https://doi.org/10.1182/blood-2022-157423
Published: 2022
Journal Articles

Analysis of Patient-Level Data from 3 Cooperative Group Trials Confirms a Survival Advantage for NPM1 m Patients Achieving MRD-Negative CR after Intensive Induction

Konstanze Döhner, Hartmut Döhner, Daniela Weber, Silke Kapp-Schwoerer, Amanda Gilkes, Ian Thomas, Sean Johnson, Nicola Potter, Yana Bevan, Jad Othman, Nigel H. Russell, Christoph Röllig, Christian Thiede, Martin Bornhaeuser, Thomas Oellerich, Jenna Elder, Luis A. Carvajal, Zung To, Jorge DiMartino, Richard Dillon
Journal: Blood
Blood (2022) 140 (Supplement 1): 6293–6294.
https://doi.org/10.1182/blood-2022-159212
Published: 2022
Journal Articles

Gemtuzumab Ozogamicin Plus Intensive Chemotherapy for Patients with NPM1 -Mutated Acute Myeloid Leukemia

Hartmut Döhner, Daniela Weber, Julia Krzykalla, Walter Fiedler, Michael W.M. Kühn, Thomas Schroeder, Karin Mayer, Michael Lübbert, Mohammad Wattad, Katharina Götze, Lars Fransecky, Elisabeth Koller, Gerald Wulf, Jan Schleicher, Mark Ringhoffer, Richard Greil, Bernd Hertenstein, Jürgen Krauter, Uwe M. Martens, David Nachbaur, Maisun Abu Samra, Sigrid Machherndl-Spandl, Nadezda Basara, Claudia Leis, Anika Schrade, Silke Kapp-Schwoerer, Lars Bullinger, Felicitas R. Thol, Michael Heuser, Peter Paschka, Verena I. Gaidzik, Maral Saadati, Axel Benner, Richard F. Schlenk, Konstanze Döhner, Arnold Ganser
Journal: Blood
Blood (2022) 140 (Supplement 1): 2010–2013.
https://doi.org/10.1182/blood-2022-166084
Published: 2022
Journal Articles

Prognostic Value of Elafin in Acute Graft-Versus-Host Disease

Makda Getachew Zewde, George Morales, Isha Gandhi, Umut Ozbek, Paibel Aguayo-Hiraldo, Francis A. Ayuk, Janna Baez, Chantiya Chanswangphuwana, Hannah Choe, Zachariah DeFilipp, Aaron Etra, Stephan A. Grupp, Elizabeth O. Hexner, William J Hogan, Rebeka Javorniczky, Stelios Kasikis, Carrie Lynn Kitko, Steven Kowalyk, Elisabeth Meedt, Pietro Merli, Ryotaro Nakamura, Muna Qayed, Ran Reshef, Wolf Roesler, Tal Schechter-Finkelstein, Daniela Weber, Matthias Wölfl, Gregory A Yanik, Rachel Young, John E. Levine, James L. Ferrara, Yi-Bin Chen
Journal: Blood
Blood (2021) 138 (Supplement 1): 3900.
https://doi.org/10.1182/blood-2021-154302
Published: 2021
Journal Articles

Midostaurin Plus Intensive Chemotherapy for Younger and Older Patients with Acute Myeloid Leukemia and FLT3 Internal Tandem Duplications

Hartmut Döhner, Daniela Weber, Julia Krzykalla, Walter Fiedler, Gerald Wulf, Helmut R. Salih, Michael Lübbert, Michael W.M. Kühn, Thomas Schroeder, Hans Salwender, Katharina S. Götze, Jörg Westermann, Lars Fransecky, Karin Mayer, Bernd Hertenstein, Mark Ringhoffer, Hans-Joachim Tischler, Sigrid Machherndl-Spandl, Anika Schrade, Peter Paschka, Verena I Gaidzik, Frauke Theis, Felicitas R Thol, Michael Heuser, Richard F. Schlenk, Lars Bullinger, Maral Saadati, Axel Benner, Konstanze Döhner, Arnold Ganser
Journal: Blood
Blood (2021) 138 (Supplement 1): 692.
https://doi.org/10.1182/blood-2021-147256
Published: 2021
Journal Articles

Longitudinal Analysis of Gut Bacteriome, Mycobiome, Virome and Metabolome in Allogeneic Stem Cell Transplantation Reveals Susceptibility for Acute Graft-Versus-Host Disease

Erik Thiele Orberg, Elisabeth Meedt, Andreas Hiergeist, Jinling Xue, Sakhila Ghimire, Melanie Tiefgraber, Tina Eismann, Sophia Göldel, Peter Herhaus, Mareike Verbeek, Florian Bassermann, Michael Quante, Daniela Weber, Matthias Edinger, Daniel Wolff, Wolfgang Herr, Li Deng, André Gessner, Ernst Holler, Hendrik Poeck
Journal: Blood
Blood (2021) 138 (Supplement 1): 332.
https://doi.org/10.1182/blood-2021-153026
Published: 2021
Journal Articles

Impact of gemtuzumab ozogamicin on MRD and relapse risk in patients with NPM1 -mutated AML: results from the AMLSG 09-09 trial

Clinical Trials & Observations
Silke Kapp-Schwoerer, Daniela Weber, Andrea Corbacioglu, Verena I. Gaidzik, Peter Paschka, Jan Krönke, Frauke Theis, Frank G. Rücker, Maria-Veronica Teleanu, Ekaterina Panina, Nikolaus Jahn, Julia Herzig, Lena Kubanek, Anika Schrade, Gudrun Göhring, Walter Fiedler, Thomas Kindler, Thomas Schroeder, Karin T. Mayer, Michael Lübbert, Mohammed Wattad, Katharina S. Götze, Heinz A. Horst, Elisabeth Koller, Gerald Wulf, Jan Schleicher, Martin Bentz, Jürgen Krauter, Lars Bullinger, Julia Krzykalla, Axel Benner, Richard F. Schlenk, Felicitas Thol, Michael Heuser, Arnold Ganser, Hartmut Döhner, Konstanze Döhner
Journal: Blood
Blood (2020) 136 (26): 3041–3050.
https://doi.org/10.1182/blood.2020005998
Published: 2020
Includes: Supplemental data
Journal Articles

Mutational Landscape of Relapsed Core-Binding Factor Acute Myeloid Leukemia (CBF-AML)

Anna Dolnik, Nikolaus Jahn, MD, Eric Sträng, PhD, Sibylle Cocciardi, PhD, Frank G. Rücker, MD, Ekaterina Panina, MD, Tamara J. Blätte, PhD, Julia Katharina Herzig, PhD, Andrea Corbacioglu, PhD, Daniela Weber, MSc, Anika Schrade, PhD, Verena I Gaidzik, MD, Sabrina Skambraks, Katharina S. Götze, Michael Luebbert, MD PhD, Walter Fiedler, MD, Thomas Schroeder, Corinna Hahn, Felicitas Thol, Michael Heuser, Arnold Ganser, Peter Paschka, MD, Hartmut Döhner, Konstanze Döhner, Lars Bullinger, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 42.
https://doi.org/10.1182/blood-2020-142392
Published: 2020
Journal Articles

Ivosidenib Improves Overall Survival Relative to Standard Therapies in Relapsed or Refractory Mutant IDH1 AML: Results from Matched Comparisons to Historical Controls

Peter Paschka, MD, Hervé Dombret, MD, Xavier Thomas, MD PhD, Christian Recher, MD PhD, Sylvain Chantepie, MD, Pau Montesinos Fernandez, MD PhD, Evelyn Acuña-Cruz, MD, Paresh Vyas, MRCP, FRCP, FRCPath, Karl-Anton Kreuzer, MD, Michael Heuser, Klaus H. Metzeler, MD, Michael Dennis, MD, Bruno Quesnel, MD PhD, Mathilde Hunault-Berger, MDPhD, Mohamad Mohty, MD PhD, Arnaud Pigneux, MD PhD, Stephane De Botton, Daniela Weber, MSc, Konstanze Döhner, Gary Milkovich, PharmD, John Reitan, PharmD, Sarah C MacDonald, SD, Deborah Casso, MPH, Michael Storm, MSc, Hua Liu, PhD, Stephanie M. Kapsalis, BS, Eyal C. Attar, MD, Thomas Winkler, MD, Hartmut Döhner, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 18–19.
https://doi.org/10.1182/blood-2020-136957
Published: 2020
Journal Articles

Higher Dose of CPX-351 Is Associated with Prolonged Hematologic Recovery: Results from an Interim Safety Analysis of the Randomized, Phase III AMLSG 30-18 Trial

Verena I Gaidzik, MD, Verena Mayr-Benedikter, Daniela Weber, MSc, Anika Schrade, PhD, Jürgen Krauter, Juliane S. Walz, MD, Holger Hebart, MD, Beate S. Schultheis, MD, Nadezda Basara, MD, Elisabeth Dietl, MD, Silke Kapp-Schwoerer, MD, Michaela Feuring-Buske, MD, Felicitas Thol, Michael Heuser, Stefan Faderl, MD, Anthony J. Wagner, Maral Saadati, Julia Krzykalla, PhD, Axel Benner, Arnold Ganser, Konstanze Döhner, Peter Paschka, MD, Hartmut Döhner
Journal: Blood
Blood (2020) 136 (Supplement 1): 46–47.
https://doi.org/10.1182/blood-2020-138738
Published: 2020
Journal Articles

Next-Generation Sequencing (NGS)-Based Measurable Residual Disease (MRD) Monitoring in Acute Myeloid Leukemia with FLT3 Internal Tandem Duplication ( FLT3 -ITD + AML) Treated with Additional Midostaurin

Julia K. Herzig, PhD, Frank G. Rücker, MD, Laura K. Schmalbrock, MD, Tamara J. Blätte, PhD, Daniela Weber, MSc, Sabrina Skambraks, Silke Kapp-Schwoerer, MD, Andrea Corbacioglu, PhD, Verena I Gaidzik, MD, Peter Paschka, MD, Ekaterina Panina, MD, Nikolaus Jahn, MD, Anika Schrade, PhD, Frauke Theis, MD, Sibylle Cocciardi, PhD, Walter Fiedler, MD, Helmut R. Salih, Gerald Wulf, MD, Hans Salwender, MD, Thomas Schroeder, Katharina S. Götze, Thomas Kindler, MD, Michael Luebbert, Richard F. Schlenk, Felicitas Thol, Michael Heuser, Arnold Ganser, Hartmut Döhner, Lars Bullinger, MD, Konstanze Döhner
Journal: Blood
Blood (2020) 136 (Supplement 1): 21–22.
https://doi.org/10.1182/blood-2020-137568
Published: 2020
Journal Articles

The microbe-derived short-chain fatty acids butyrate and propionate are associated with protection from chronic GVHD

Clinical Trials & Observations Brief Report
Kate A. Markey, Jonas Schluter, Antonio L. C. Gomes, Eric R. Littmann, Amanda J. Pickard, Bradford P. Taylor, Paul A. Giardina, Daniela Weber, Anqi Dai, Melissa D. Docampo, Gabriel K. Armijo, Ann E. Slingerland, John B. Slingerland, Katherine B. Nichols, Daniel G. Brereton, Annelie G. Clurman, Ruben J. Ramos, Arka Rao, Amy Bush, Lauren Bohannon, Megan Covington, Meagan V. Lew, David A. Rizzieri, Nelson Chao, Molly Maloy, Christina Cho, Ioannis Politikos, Sergio Giralt, Ying Taur, Eric G. Pamer, Ernst Holler, Miguel-Angel Perales, Doris M. Ponce, Sean M. Devlin, Joao Xavier, Anthony D. Sung, Jonathan U. Peled, Justin R. Cross, Marcel R. M. van den Brink
Journal: Blood
Blood (2020) 136 (1): 130–136.
https://doi.org/10.1182/blood.2019003369
Published: 2020
Includes: Supplemental data
Journal Articles

The MAGIC Algorithm Probability (MAP): A Novel Laboratory Biomarker for the Response to Treatment of Acute Graft-Versus-Host Disease

Hrishikesh Srinagesh, BA, Umut Ozbek, PhD, Urvi Kapoor, MD, Francis Ayuketang Ayuk, MD, Mina D. Aziz, MD, Kaitlyn Ben-David, Hannah K. Choe, MD, Zachariah Defilipp, MD, Aaron Etra, MD, Stephan Grupp, MD PhD, Matthew Hartwell, MD, Elizabeth O. Hexner, MDMS, William J Hogan, MB, BCh, Carrie Kitko, MD, Steven Kowalyk, Jung-Yi Lin, MS, Hannah Major-Monfried, MD MSCR, Stephan Mielke, MD, Pietro Merli, MD, George Morales, Rainer Ordemann, MD, Michael A. Pulsipher, MD, Muna Qayed, MD MSc, Pavan Reddy, Ran Reshef, MD MSc, Wolf Roesler, MD, Karamjeet S. Sandhu, MD, Tal Schechter-Finkelstein, MD, Jay Shah, MD, Keith Sigel, MD PhD, Daniela Weber, MD, Matthias Wölfl, MD, Kitsada Wudhikarn, MD, Rachel Young, John E. Levine, MDMS, James L. M. Ferrara, MDDSc
Journal: Blood
Blood (2019) 134 (Supplement_1): 367.
https://doi.org/10.1182/blood-2019-122011
Published: 2019
Journal Articles

Improved Overall Survival with Enasidenib Compared with Standard of Care Among Patients with Relapsed or Refractory Acute Myeloid Leukemia and IDH2 Mutations: A Propensity Score Matching Analysis Using Data from the AG221-C-001 Trial and Two Data Sources from France and Germany

Stephane De Botton, Joseph M Brandwein, MD, Eytan M. Stein, MD, Andrew H. Wei, Daniela Weber, Arnaud Pigneux, Nicolas Boissel, MD PhD, Peter Paschka, MD, Konstanze Döhner, Salem Abi Nehme, Mark G. Frattini, MD, Roland Marion-Gallois, Jixian (Jason) Wang, Chris Cameron, Muhaimen Siddiqui, Rana A. Qadeer, Hartmut Döhner
Journal: Blood
Blood (2019) 134 (Supplement_1): 3893.
https://doi.org/10.1182/blood-2019-122700
Published: 2019
Journal Articles

Measurable Residual Disease (MRD) Monitoring in Acute Myeloid Leukemia (AML) with t(8;21)(q22;q22.1) RUNX1 - RUNX1T1 Identifies Patients at High Risk of Relapse: Results of the AML Study Group (AMLSG)

Frank G. Rücker, MD, Mridul Agrawal, MDMSc, Andrea Corbacioglu, PhD, Daniela Weber, Silke Kapp-Schwoerer, MD, Verena I. Gaidzik, MD, Nikolaus Jahn, MD, Thomas Schroeder, MD, Mohammad Wattad, MD, Michael Lübbert, Elisabeth Koller, MD, Thomas Kindler, MD, Katharina Götze, Mark Ringhoffer, MD, Jörg Westermann, MD, Walter Fiedler, MD, Heinz A. Horst, MD, Richard Greil, MD, Roland Schroers, Karin Mayer, MD, Thomas Heinicke, MD, Jürgen Krauter, MD, Richard F. Schlenk, MD, Felicitas Thol, MD, Michael Heuser, MD, Arnold Ganser, MD, Lars Bullinger, Peter Paschka, MD, Hartmut Döhner, MD, Konstanze Döhner
Journal: Blood
Blood (2019) 134 (Supplement_1): 2740.
https://doi.org/10.1182/blood-2019-125584
Published: 2019
Journal Articles

Measurable residual disease monitoring in acute myeloid leukemia with t(8;21)(q22;q22.1): results from the AML Study Group

Frank G. Rücker, Mridul Agrawal, Andrea Corbacioglu, Daniela Weber, Silke Kapp-Schwoerer, Verena I. Gaidzik, Nikolaus Jahn, Thomas Schroeder, Mohammed Wattad, Michael Lübbert, Elisabeth Koller, Thomas Kindler, Katharina Götze, Mark Ringhoffer, Jörg Westermann, Walter Fiedler, Heinz A. Horst, Richard Greil, Roland Schroers, Karin Mayer, Thomas Heinicke, Jürgen Krauter, Richard F. Schlenk, Felicitas Thol, Michael Heuser, Arnold Ganser, Lars Bullinger, Peter Paschka, Hartmut Döhner, Konstanze Döhner
Journal: Blood
Blood (2019) 134 (19): 1608–1618.
https://doi.org/10.1182/blood.2019001425
Published: 2019
Includes: Supplemental data