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Journal Articles

A Day 14 Endpoint for Acute Gvhd Clinical Trials

Blood (2023) 142 (Supplement 1): 779.

https://doi.org/10.1182/blood-2023-172955

Published: 2023

Journal Articles

A Multicentre, Randomized, Double-Blinded, Phase 2b Study Evaluating the Efficacy and Safety of MaaT033, an Oral, Pooled Microbiome Ecosystem Therapy in Patients Undergoing Allogenic Hematopoietic Cell Transplantation to Improve Overall Survival: The Phoebus Trial

Florent Malard, Myriam Labopin, Ernst Holler, Joël Doré, Emilie Plantamura, Mohamad Mohty

Blood (2023) 142 (Supplement 1): 4947.

https://doi.org/10.1182/blood-2023-185639

Published: 2023

Journal Articles

Bacterial and Bacteriophage Consortia Are Associated with Protective Intestinal Immuno-Modulatory Metabolites in Allogeneic Stem Cell Transplantation Patients

Blood (2023) 142 (Supplement 1): 477.

https://doi.org/10.1182/blood-2023-172457

Published: 2023

Journal Articles

Harnessing the Expression of TNFR2 on Tregs to Prevent Agvhd

Juan Gamboa Vargas, Carla Kanzler, Lukas Scheller, Jennifer Kreckel, Haroon Shaikh, Isabell Lang, Juliane Medler, Mohamed Anany, Tim Steinfatt, Julia Hartweg, Stefanie Haack, Ernst Holler, Maike Büttner-Herold, Paula Tabares Gaviria, Harald Wajant, Andreas Beilhack, Hermann Einsele

Blood (2022) 140 (Supplement 1): 4465–4466.

https://doi.org/10.1182/blood-2022-168592

Published: 2022

Journal Articles

Immunomodulatory Microbial Metabolites Identified in Allo-SCT Patients Protect from GvHD By Sting Dependent Modulation of Intestinal Tissue Homeostasis

Sascha Göttert, Erik Thiele-Orberg, Kaiji Fan, Sakhila Ghimire, Paul Heinrich, Wolfgang Herr, Simon Heidegger, Ernst Holler, Hendrik Poeck

Blood (2022) 140 (Supplement 1): 7336–7337.

https://doi.org/10.1182/blood-2022-169118

Published: 2022

Journal Articles

Inhibition of the Receptor Interactive Protein Kinase 1 (RIP1) Pathway Prevents Acute Gvhd

James L.M. Ferrara, Mariano Prado Acosta, Seihwan Jeong, John E. Levine, Ernst Holler, Joshua Webster, George Morales, Domagoj Vucic

Blood (2022) 140 (Supplement 1): 7330–7331.

https://doi.org/10.1182/blood-2022-163730

Published: 2022

Journal Articles

IFN-Gamma Is Crucial for the Counterbalance of T Cell-Mediated Injury to the Intestinal Stem Cell Compartment By Regulatory T Cells in Mice and Humans

Sascha Göttert, Julius Clemens Fischer, Gabriel Eisenkolb, Erik Thiele Orberg, Sebastian Jarosch, Ernst Holler, Dirk Busch, Simon Heidegger, Hendrik Poeck

Blood (2022) 140 (Supplement 1): 10223–10224.

https://doi.org/10.1182/blood-2022-169303

Published: 2022

Journal Articles

Identification of Bacterial and Viral Consortia for the Production of Intestinal Microbiota-Derived Metabolites Associated with Protection in Allogeneic Stem Cell Transplantation Patients

Blood (2022) 140 (Supplement 1): 7619–7621.

https://doi.org/10.1182/blood-2022-157423

Published: 2022

Journal Articles

IFN-Gamma Producing Regulatory T Cells Counterbalance T Cell-Mediated Injury to the Intestinal Stem Cell Compartment in Mice and Humans

Sascha Göttert, Julius Clemens Fischer, Gabriel Eisenkolb, Erik Thiele Orberg, Dirk Busch, Sebastian Jarosch, Ernst Holler, Thomas Engleitner, Lena Klostermeier, Caroline Walther, Laura Lansink Rotgerink, Sophie Nefzger, Marianne Reiser, Katja Steiger, Roland Rad, Stefanie E. Combs, Florian Bassermann, Simon Heidegger, Hendrik Poeck

Blood (2021) 138 (Supplement 1): 89.

https://doi.org/10.1182/blood-2021-152925

Published: 2021

Journal Articles

Microbial-Derived Metabolites Induce Epithelial Recovery Via the Sting Pathway in Mice and Men and Protect from Graft-Versus-Host Disease

Erik Thiele Orberg, Sascha Göttert, Andreas Hiergeist, Elisabeth Meedt, Karin Kleigrewe, Wolfgang Herr, Florian Bassermann, Andre Gessner, Ernst Holler, Simon Heidegger, Hendrik Poeck

Blood (2021) 138 (Supplement 1): 87.

https://doi.org/10.1182/blood-2021-147794

Published: 2021

Journal Articles

Pooled Allogenic Fecal Microbiotherapy MaaT013 for the Treatment of Steroid-Refractory Gastrointestinal Acute Graft-Versus-Host Disease: Results from the Phase IIa Heracles Study and Expanded Access Program

Blood (2021) 138 (Supplement 1): 262.

https://doi.org/10.1182/blood-2021-147709

Published: 2021

Journal Articles

Longitudinal Analysis of Gut Bacteriome, Mycobiome, Virome and Metabolome in Allogeneic Stem Cell Transplantation Reveals Susceptibility for Acute Graft-Versus-Host Disease

Blood (2021) 138 (Supplement 1): 332.

https://doi.org/10.1182/blood-2021-153026

Published: 2021

Journal Articles

Refractory acute graft-versus-host disease: a new working definition beyond corticosteroid refractoriness

Mohamad Mohty, Ernst Holler, Madan Jagasia, Robert Jenq, Florent Malard, Paul Martin, Gérard Socié, Robert Zeiser

Blood (2020) 136 (17): 1903–1906.

https://doi.org/10.1182/blood.2020007336

Published: 2020

Journal Articles

The microbe-derived short-chain fatty acids butyrate and propionate are associated with protection from chronic GVHD

Blood (2020) 136 (1): 130–136.

https://doi.org/10.1182/blood.2019003369

Published: 2020

Includes: Supplemental data

Journal Articles

Outcome of Allogeneic Haematopoietic Stem Cell Transplantation in Myeloproliferative Neoplasms-Unclassifiable: A Retrospective Study By the Chronic Malignancies Working Party of EBMT

Blood (2019) 134 (Supplement_1): 3335.

https://doi.org/10.1182/blood-2019-121820

Published: 2019

Journal Articles

Intestinal Enterococcus Is a Major Risk Factor for the Development of Acute Gvhd

Christoph K. Stein-Thoeringer, MD, Jonathan U. Peled, MD PhD, Antonio LC Gomes, PhD, Amina Lazrak, BS, Melissa D Docampo, BS, Ann E. Slingerland, BSc, Katherine Nichols, BS, Yusuke Shono, MD PhD, Daniela Weber, MD, Anthony D. Sung, MD, Daigo Hashimoto, MD, PhD, Justin Cross, PhD, Takanori Teshima, Ernst Holler, MD, Nelson J. Chao, MD, Eric G. Pamer, MD, Marcel R.M. van den Brink, MD PhD

Blood (2018) 132 (Supplement 1): 358.

https://doi.org/10.1182/blood-2018-99-119887

Published: 2018

Journal Articles

The Role of Donor Selection for a Second Allogeneic Stem Cell Transplantation in Patients with AML Relapsing after a First Transplant; A Study on Behalf of the Acute Leukemia Working Party of EBMT

Avichai Shimoni, MD, Myriam Labopin, MD, Jürgen Finke, MD, Fabio Ciceri, MD, Eric Deconinck, MD PhD, Nicolaus Kröger, MD, Martin Gramatzki, MD, Matthias Stelljes, MD, Didier Blaise, Friedrich Stoelzel, Patrice Chevallier, MD, Ernst Holler, MD PhD, Nathalie Fegueux, Mohamad Mohty, MD PhD, Arnon Nagler, MD

Blood (2018) 132 (Supplement 1): 3460.

https://doi.org/10.1182/blood-2018-99-110614

Published: 2018

Journal Articles

Outcome of Patients with Acute Myeloid Leukemia (AML) Undergoing Allogeneic Hematopoietic Stem Cell Transplantation (HSCT) Beyond First Complete Remission (CR1)

Georg Evers, MD, Dietrich W. Beelen, Jan Braess, MD, Cristina Sauerland, Hans-Jochem Kolb, MD, Albrecht Reichle, MD, Ernst Holler, MD, Rainer Schwerdtfeger, MD, Renate Arnold, MD, Christoph Scheid, MD, Utz Krug, MD, Carsten Müller-Tidow, MD, Christoph Schliemann, MD, Jan-Henrik Mikesch, MD, Georg Lenz, Bernhard J. Wörmann, MD, Wolfgang Hiddemann, Wolfgang E. Berdel, MD, Matthias Stelljes, MD

Blood (2018) 132 (Supplement 1): 4649.

https://doi.org/10.1182/blood-2018-99-116964

Published: 2018

Journal Articles

Assessment of Calcineurin Inhibitor-Associated Neurotoxicity in Patients with Sickle Cell Disease Receiving a Matched Sibling Donor or T-Cell Depleted Haploidentical Hematopoietic Stem Cell Transplantation

Katharina Kleinschmidt, MD PhD, Juergen Foell, MD, Johannes Schulte, Beatrix Pfirstinger, MD, Anja Troeger, MD, Charalampos Aslanidis, PhD, Daniel Wolff, MD, Matthias Edinger, MD PhD, Ernst Holler, MD, Wolfgang Herr, MD, Angelika Eggert, MD PhD, Selim Corbacioglu, MD

Blood (2018) 132 (Supplement 1): 2088.

https://doi.org/10.1182/blood-2018-99-115988

Published: 2018

Journal Articles

Multicenter Microbiota Analysis Indicates That Pre-HCT Microbiota Injury Is Prevalent across Geography and Predicts Poor Overall Survival

Blood (2018) 132 (Supplement 1): 811.

https://doi.org/10.1182/blood-2018-99-116967

Published: 2018

NARROW

A Day 14 Endpoint for Acute Gvhd Clinical Trials

A Multicentre, Randomized, Double-Blinded, Phase 2b Study Evaluating the Efficacy and Safety of MaaT033, an Oral, Pooled Microbiome Ecosystem Therapy in Patients Undergoing Allogenic Hematopoietic Cell Transplantation to Improve Overall Survival: The Phoebus Trial

Bacterial and Bacteriophage Consortia Are Associated with Protective Intestinal Immuno-Modulatory Metabolites in Allogeneic Stem Cell Transplantation Patients

Harnessing the Expression of TNFR2 on Tregs to Prevent Agvhd

Immunomodulatory Microbial Metabolites Identified in Allo-SCT Patients Protect from GvHD By Sting Dependent Modulation of Intestinal Tissue Homeostasis

Inhibition of the Receptor Interactive Protein Kinase 1 (RIP1) Pathway Prevents Acute Gvhd

IFN-Gamma Is Crucial for the Counterbalance of T Cell-Mediated Injury to the Intestinal Stem Cell Compartment By Regulatory T Cells in Mice and Humans

Identification of Bacterial and Viral Consortia for the Production of Intestinal Microbiota-Derived Metabolites Associated with Protection in Allogeneic Stem Cell Transplantation Patients

IFN-Gamma Producing Regulatory T Cells Counterbalance T Cell-Mediated Injury to the Intestinal Stem Cell Compartment in Mice and Humans

Microbial-Derived Metabolites Induce Epithelial Recovery Via the Sting Pathway in Mice and Men and Protect from Graft-Versus-Host Disease

Pooled Allogenic Fecal Microbiotherapy MaaT013 for the Treatment of Steroid-Refractory Gastrointestinal Acute Graft-Versus-Host Disease: Results from the Phase IIa Heracles Study and Expanded Access Program

Longitudinal Analysis of Gut Bacteriome, Mycobiome, Virome and Metabolome in Allogeneic Stem Cell Transplantation Reveals Susceptibility for Acute Graft-Versus-Host Disease

Refractory acute graft-versus-host disease: a new working definition beyond corticosteroid refractoriness

The microbe-derived short-chain fatty acids butyrate and propionate are associated with protection from chronic GVHD

Outcome of Allogeneic Haematopoietic Stem Cell Transplantation in Myeloproliferative Neoplasms-Unclassifiable: A Retrospective Study By the Chronic Malignancies Working Party of EBMT

Intestinal Enterococcus Is a Major Risk Factor for the Development of Acute Gvhd

The Role of Donor Selection for a Second Allogeneic Stem Cell Transplantation in Patients with AML Relapsing after a First Transplant; A Study on Behalf of the Acute Leukemia Working Party of EBMT

Outcome of Patients with Acute Myeloid Leukemia (AML) Undergoing Allogeneic Hematopoietic Stem Cell Transplantation (HSCT) Beyond First Complete Remission (CR1)

Assessment of Calcineurin Inhibitor-Associated Neurotoxicity in Patients with Sickle Cell Disease Receiving a Matched Sibling Donor or T-Cell Depleted Haploidentical Hematopoietic Stem Cell Transplantation

Multicenter Microbiota Analysis Indicates That Pre-HCT Microbiota Injury Is Prevalent across Geography and Predicts Poor Overall Survival

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American Society of Hematology

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American Society of Hematology

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