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Journal Articles

Epigenetic Classification of Acute Myeloid Leukemia Revealed By Genome-Wide Chromatin Profiling

Yotaro Ochi, Yasuhito Nannya, Markus Liew-Littorin, Senji Kasahara, Nobuhiro Hiramoto, Nobuhiro Kanemura, Nobuo Sezaki, Maki Sakurada, Makoto Iwasaki, Junya Kanda, Yasunori Ueda, Satoshi Yoshihara, Albin Osterroos, Masanori Motomura, Masahiro Marshall Nakagawa, Ryunosuke Saiki, Akinori Yoda, Rurika Okuda, Yuichi Shiraishi, Takayuki Ishikawa, Satoru Miyano, Akifumi Takaori-Kondo, Soren Lehmann, Seishi Ogawa
Journal: Blood
Blood (2023) 142 (Supplement 1): 836.
https://doi.org/10.1182/blood-2023-180336
Published: 2023
Journal Articles

Donor NK Cell Education By KIR3DL1 and HLA-B Associates with Reduced Relapse in Unrelated Bone Marrow Transplantation for Adult T-Cell Leukemia

Mari Morita-Fujita, Takero Shindo, Shuji Kawaguchi, Kiyotaka Izumi, Yuichi Inadomi, Masakazu Shimizu, Ai Murano, Akiyo Morinibu, Meiko Takahashi, Junya Kanda, Taro Tsujimura, Takuya Yamamoto, Koji Kato, Hidenori Tanaka, Nobuaki Nakano, Tetsuya Eto, Yasuhiko Miyazaki, Kazunori Imada, Youko Suehiro, Toshiro Kawakita, Tatsuo Ichinohe, Takahiro Fukuda, Makoto Onizuka, Yoshiko Atsuta, Fumihiko Matsuda, Akifumi Takaori-Kondo
Journal: Blood
Blood (2023) 142 (Supplement 1): 4982.
https://doi.org/10.1182/blood-2023-185474
Published: 2023
Journal Articles

Practical and Flexible Genome Profiling Study Using the Halo-Shape Annealing and Defer-Ligation Enrichment (HANDLE) System: HM-Screen-JAPAN02

Naoko Hosono, Takahiro Yamauchi, Chi Sung-Gi, Hironori Arai, Kentaro Fukushima, Daisuke Ikeda, Satoshi Iyama, Akihiko Gotoh, Takayuki Ikezoe, Chikashi Yoshida, Goichi Yoshimoto, Junya Kanda, Naoto Takahashi, Emiko Sakaida, Kensuke Usuki, Yosuke Minami
Journal: Blood
Blood (2023) 142 (Supplement 1): 2279.
https://doi.org/10.1182/blood-2023-184546
Published: 2023
Journal Articles

Impact of Conditioning Intensity and Regimen on Outcomes after Unrelated Cord Blood Transplantation for Patients with Myelodysplastic Syndrome

Machiko Fujioka, Hidehiro Itonaga, Yasushi Miyazaki, Yoshimitsu Shimomura, Naoyuki Uchida, Satoshi Takahashi, Makoto Onizuka, Yasunori Ueda, Yasufumi Uehara, Masatsugu Tanaka, Yoshiko Matsuhashi, Shigesaburo Miyakoshi, Haruyuki Tanaka, Toshiro Kawakita, Fumihiko Ishimaru, Junya Kanda, Tatsuo Ichinohe, Yoshiko Atsuta, Ken Ishiyama
Journal: Blood
Blood (2023) 142 (Supplement 1): 3536.
https://doi.org/10.1182/blood-2023-179157
Published: 2023
Journal Articles

Effect of Early Cytomegalovirus Reactivation on Relapse in Adult Patients with Myelodysplastic Syndromes after Allogeneic Hematopoietic Stem Cell Transplantation: A Registry Study from the Japan Society for Transplantation and Cellular Therapy (JSTCT)

Tatsuya Konishi, Kensuke Matsuda, Hidehiro Itonaga, Noriko Doki, Tetsuya Nishida, Ken-Ichi Matsuoka, Takashi Ikeda, Yoshinobu Kanda, Takahiro Fukuda, Junya Kanda, Hirohisa Nakamae, Tatsuo Ichinohe, Yoshiko Atsuta, Ken Ishiyama
Journal: Blood
Blood (2023) 142 (Supplement 1): 2170.
https://doi.org/10.1182/blood-2023-172414
Published: 2023
Journal Articles

Comparison of Non-Relapse Mortality after Haploidentical Hematopoietic Stem Cell Transplantation with Post-Transplant Cyclophosphamide Versus Single Umbilical Cord Blood Transplantation for Hematologic Disease

Kaito Harada, Junya Kanda, Masahiro Hirayama, Fumiya Wada, Naoyuki Uchida, Hirohisa Nakamae, Masatsugu Tanaka, Makoto Onizuka, Hiroyuki Ohigashi, Nobuaki Nakano, Takahiro Fukuda, Kazuya Ishiwata, Yumiko Maruyama, Tetsuya Eto, Fumihiko Ishimaru, Yoshiko Atsuta, Hideki Nakasone, Takashi Tanaka
Journal: Blood
Blood (2023) 142 (Supplement 1): 4905.
https://doi.org/10.1182/blood-2023-184821
Published: 2023
Journal Articles

Identification of Novel Transcripts and Potential Therapeutic Targets for Acute Leukemia

Fumiya Wada, Shoya Kato, Shruti Bhagat, Shigeki Hirabayashi, Raku Son, Akiko Oguchi, Kazuhiro Takeuchi, Sho Sekito, Tomoya Hirai, Zhiwei Zhang, Yoshihito Horisawa, Makoto Iwasaki, June Takeda, Junya Kanda, Takashi Sakamoto, Kotaro Shirakawa, Akifumi Takaori-Kondo, Yasuhiro Murakawa
Journal: Blood
Blood (2023) 142 (Supplement 1): 1583.
https://doi.org/10.1182/blood-2023-188008
Published: 2023
Journal Articles

The Comparison between BM and PBSC for the Patients with Pre-Transplant Pulmonary Dysfunction in HLA-Matched Allo-HCT: Subgroup Analysis Exploring the Impact Based on HCT Factors

Shunto Kawamura, Masaharu Tamaki, Takaaki Konuma, Makoto Onizuka, Emiko Sakaida, Hiromi Hayashi, Noriko Doki, Tetsuya Nishida, Masashi Sawa, Hiroyuki Ohigashi, Takahiro Fukuda, Jun Ishikawa, Ken-ichi Matsuoka, Toshiro Kawakita, Masatsugu Tanaka, Fumihiko Ishimaru, Tatsuo Ichinohe, Yoshiko Atsuta, Yoshinobu Kanda, Kimikazu Yakushijin, Junya Kanda, Hideki Nakasone
Journal: Blood
Blood (2023) 142 (Supplement 1): 3609.
https://doi.org/10.1182/blood-2023-174431
Published: 2023
Journal Articles

Recurrence of HBV Reactivation after Allogeneic Hematopoietic Transplantation in Recipients with Resolved HBV Infection: A Nation-Wide Multicenter Retrospective Study

Masahiro Onozawa, Shigeru Kusumoto, Yuho Najima, Hiroya Hashimoto, Kohei Okada, Masaharu Tamaki, Masatsugu Tanaka, Takayuki Sato, Tsutomu Takahashi, Kaoru Hatano, Koichi Onodera, Yukiyoshi Moriuchi, Kimikazu Yakushijin, Junya Kanda, Koji Nagafuji, Masao Ogata, Nobuaki Nakano, Akihiro Tamori, Masashi Mizokami
Journal: Blood
Blood (2023) 142 (Supplement 1): 3541.
https://doi.org/10.1182/blood-2023-173461
Published: 2023
Journal Articles

Impact of Early Anti-Cytomegalovirus Therapy on the Incidence of Chronic Graft-Versus-Host Disease

Kotaro Miyao, Makoto Murata, Tetsuya Nishida, Yukiyasu Ozawa, Naoyuki Uchida, Takahiro Fukuda, Noriko Doki, Tetsuya Eto, Toshiro Kawakita, Yasuo Mori, Satoru Takada, Hiroyuki Ohigashi, Masatsugu Tanaka, Yoshinobu Kanda, Ken-ichi Matsuoka, Fumihiko Ishimaru, Yoshiko Atsuta, Junya Kanda, Seitaro Terakura
Journal: Blood
Blood (2023) 142 (Supplement 1): 6993.
https://doi.org/10.1182/blood-2023-178592
Published: 2023
Journal Articles

Identifying the Optimal Conditioning Intensity of Hematopoietic Stem Cell Transplantation in Patients with Acute Myeloid Leukemia in Complete Remission

Yoshimitsu Shimomura, Sho Komukai, Tetsuhisa Kitamura, Tomotaka Sobue, Satoshi Yamasaki, Tadakazu Kondo, Shohei Mizuno, Kaito Harada, Noriko Doki, Masatsugu Tanaka, Ayumu Ito, Tetsuya Nishida, Hiroyuki Ohigashi, Naoyuki Uchida, Ken-ichi Matsuoka, Yoshinobu Kanda, Makoto Onizuka, Toshiro Kawakita, Nobuhiro Hiramoto, Masashi Sawa, Kentaro Fukushima, Junya Kanda, Takahiro Fukuda, Yoshiko Atsuta, Masamitsu Yanada
Journal: Blood
Blood (2023) 142 (Supplement 1): 2150.
https://doi.org/10.1182/blood-2023-181621
Published: 2023
Journal Articles

Development of a Stacked Ensemble Model for Risk Stratification of Chronic Gvhd after Allogeneic HSCT: Trump Cohort Study

Makoto Iwasaki, Junya Kanda, Fumihiko Kimura, Sachiko Seo, Yoshiko Atsuta, Naoyuki Uchida, Noriko Doki, Takahiro Fukuda, Tetsuya Nishida, Yuta Katayama, Masatsugu Tanaka, Tetsuya Eto, Kazuhiro Ikegame, Yoshinobu Kanda, Masashi Sawa, Makoto Onizuka, Moeko Hino, Tatsuo Ichinohe, Ken Tabuchi, Akifumi Takaori-Kondo
Journal: Blood
Blood (2023) 142 (Supplement 1): 3561.
https://doi.org/10.1182/blood-2023-173779
Published: 2023
Journal Articles

Prognostic Impact of Chromosomal Abnormalities in TP53 -Mutated Acute Myeloid Leukemia and High-Risk Myelodysplastic Syndromes

June Takeda, Makoto Iwasaki, Junya Kanda, Yasuhito Nannya, Nobuhiro Hiramoto, Tadakazu Kondo, Takayuki Ishikawa, Mitsumasa Watanabe, Takahito Kawata, Takeshi Maeda, Yasunori Ueda, Kazunori Imada, Toshiyuki Kitano, Masaaki Tsuji, Yoshitomo Maesako, Satoko Oka, Yasuhiro Tanaka, Takashi Miyoshi, Kosuke Asagoe, Mitsuru Itoh, Hirokazu Hirata, Hiroshi Kawabata, Masakatsu Hishizawa, Akinori Maeda, Kazuhiro Yago, Nana Sasaki, Nobuhiko Uoshima, Seishi Ogawa, Akifumi Takaori-Kondo
Journal: Blood
Blood (2023) 142 (Supplement 1): 4328.
https://doi.org/10.1182/blood-2023-180291
Published: 2023
Journal Articles

Antibody-mediated pathogenesis of chronic GVHD through DBY/HLA class II complexes and induction of a GVL effect

Kento Umino, Kaoru Morita, Takashi Ikeda, Shin-ichiro Kawaguchi, Takashi Nagayama, Shoko Ito, Daisuke Minakata, Masahiro Ashizawa, Chihiro Yamamoto, Kaoru Hatano, Kazuya Sato, Ken Ohmine, Shin-ichiro Fujiwara, Shun-ichi Kimura, Shinichi Kako, Noriko Doki, Yukiyasu Ozawa, Yasuo Mori, Tetsuya Eto, Nobuhiro Hiramoto, Hirohisa Nakamae, Junya Kanda, Tatsuo Ichinohe, Yoshiko Atsuta, Hideki Nakasone, Satoko Morishima, Yoshinobu Kanda
Journal: Blood
Blood (2023) 142 (11): 1008–1021.
https://doi.org/10.1182/blood.2023019799
Published: 2023
Includes: Supplemental data
Journal Articles

iPLAT1: the first-in-human clinical trial of iPSC-derived platelets as a phase 1 autologous transfusion study

Clinical Trials & Observations
Naoshi Sugimoto, Junya Kanda, Sou Nakamura, Toshiyuki Kitano, Masakatsu Hishizawa, Tadakazu Kondo, Shin Shimizu, Akiko Shigemasa, Hideyo Hirai, Yasuyuki Arai, Manabu Minami, Harue Tada, Dai Momose, Ki-Ryang Koh, Masayuki Nogawa, Naohide Watanabe, Shinichiro Okamoto, Makoto Handa, Akira Sawaguchi, Nobuki Matsuyama, Mitsunobu Tanaka, Tomoya Hayashi, Akihiro Fuchizaki, Yoshihiko Tani, Akifumi Takaori-Kondo, Koji Eto
Journal: Blood
Blood (2022) 140 (22): 2398–2402.
https://doi.org/10.1182/blood.2022017296
Published: 2022
Includes: Supplemental data
Journal Articles

Mutational Analysis of DNMT3A Improves the Prognostic Stratification Using NPM1 / FLT3 -ITD Genotypes in Patients with Acute Myeloid Leukemia

Atsushi Marumo, Satoshi Wakita, Kaoru Morita, Shinichi Kako, Takashi Toya, Yuho Najima, Noriko Doki, Junya Kanda, Junya Kuroda, Shin-Ichiro Mori, Atsushi Satake, Kensuke Usuki, Toshimitsu Ueki, Nobuhiko Uoshima, Yutaka Kobayashi, Eri Kawata, Kazutaka Nakayama, Yuhei Nagao, Katsuhiro Shono, Motoharu Shibusawa, Jiro Tadokoro, Masao Hagihara, Hitoji Uchiyama, Naoyuki Uchida, Yasushi Kubota, Shinya Kimura, Hisao Nagoshi, Tatsuo Ichinohe, Saiko Kurosawa, Sayuri Motomura, Hashimoto Akiko, Hideharu Muto, Eriko Sato, Masao Ogata, Kenjiro Mitsuhashi, Jun Ando, Haruko Tashiro, Masahiro Sakaguchi, Shunsuke Yui, Kunihito Arai, Tomoaki Kitano, Miho Miyata, Takahiro Fukuda, Yoshinobu Kanda, Hiroki Yamaguchi
Journal: Blood
Blood (2022) 140 (Supplement 1): 8914–8916.
https://doi.org/10.1182/blood-2022-158686
Published: 2022
Journal Articles

International Collaborative Study to Compare the Prognosis for Acute Leukemia Patients Transplanted with Intensified Myeloablative Regimens

Yasuyuki Arai, Yoshiko Atsuta, Ruta Brazauskas, Naya He, Shahrukh Hashmi, Leslie E. Lehmann, William A. Wood, Jr., Hemalatha G. Rangarajan, Shingo Yano, Shinichi Kako, Masamitsu Yanada, Yukiyasu Ozawa, Noriko Doki, Yoshinobu Kanda, Takahiro Fukuda, Yuta Katayama, Tatsuo Ichinohe, Junji Tanaka, Junya Kanda, Takanori Teshima, Shinichiro Okamoto, Wael Saber
Journal: Blood
Blood (2022) 140 (Supplement 1): 4711–4713.
https://doi.org/10.1182/blood-2022-160305
Published: 2022
Journal Articles

Risk Stratified Therapy with Nelarabine and Intensified Administration of L-Asparaginase for Newly Diagnosed T-Cell Acute Lymphoblastic Leukemia in Adolescents and Young Adults (JPLSG T-11/JALSG T-ALL-211-U): An Intergroup Phase 2 Study

Yoshihiro Hatta, Atsushi Sato, Akiko Kada, Akiko Moriya Saito, Fumihiko Hayakawa, Arata Watanabe, Tatsuhiro Sakamoto, Katsuhiro Miura, Yoshifumi Shimizu, Junya Kanda, Yasushi Onishi, Noboru Asada, Yasuhiro Okamoto, Chihaya Imai, Koichi Oshima, Katsuyoshi Koh, Atsushi Manabe, Keizo Horibe, Hitoshi Kiyoi, Itaru Matsumura, Yasushi Miyazaki
Journal: Blood
Blood (2022) 140 (Supplement 1): 124–126.
https://doi.org/10.1182/blood-2022-156613
Published: 2022
Journal Articles

A Practice-Oriented Genome Profiling Study with the Novel Halo-Shape Annealing and Defer-Ligation Enrichment (HANDLE) System : HM-Screen-JAPAN02

Hironori Arai, SungGi Chi, Yoshikazu Utsu, Shinichi Masuda, Nobuyuki Aotsuka, Tomoaki Ueda, Kentaro Fukushima, Daisuke Ikeda, Naoko Hosono, Takahiro Yamauchi, Goichi Yoshimoto, Hiroto Horiguchi, Satoshi Iyama, Junya Kanda, Seiichiro Katagiri, Akihiko Gotoh, Daisuke Koyama, Takayuki Ikezoe, Takeshi Kondo, Yukinori Nakamura, Fumiya Ogasawara, Suguru Fukuhara, Koji Izutsu, Nobuhiko Yamauchi, Junichiro Yuda, Yosuke Minami
Journal: Blood
Blood (2022) 140 (Supplement 1): 10722–10724.
https://doi.org/10.1182/blood-2022-159351
Published: 2022
Journal Articles

The Novel Scoring System to Personalize the Conditioning Intensity in Elderly Patients

Yu Akahoshi, Yuma Tada, Emiko Sakaida, Machiko Kusuda, Noriko Doki, Naoyuki Uchida, Takahiro Fukuda, Masatsugu Tanaka, Masashi Sawa, Yuta Katayama, Ken-ichi Matsuoka, Yukiyasu Ozawa, Makoto Onizuka, Junya Kanda, Yoshinobu Kanda, Yoshiko Atsuta, Hideki Nakasone
Journal: Blood
Blood (2022) 140 (Supplement 1): 2123–2125.
https://doi.org/10.1182/blood-2022-160037
Published: 2022