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Yachiyo Kuwatsuka
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Journal Articles

AKATSUKI 48-Week Interim Analysis: Emicizumab and Immune Tolerance Induction in People with Hemophilia A and Factor VIII Inhibitors

Tadashi Matsushita, Nobuaki Suzuki, Chiai Nagae, Azusa Nagao, Masahiko Ando, Yachiyo Kuwatsuka, Daisuke Nosaka, Yui Kyogoku, Tomomi Shimura, Keiji Nogami
Journal: Blood
Blood (2023) 142 (Supplement 1): 2625.
https://doi.org/10.1182/blood-2023-173071
Published: 2023
Journal Articles

Two novel high-risk adult B-cell acute lymphoblastic leukemia subtypes with high expression of CDX2 and IDH1/2 mutations

Clinical Trials & Observations
Takahiko Yasuda, Masashi Sanada, Masahito Kawazu, Shinya Kojima, Shinobu Tsuzuki, Hiroo Ueno, Eisuke Iwamoto, Yuka Iijima-Yamashita, Tomomi Yamada, Takashi Kanamori, Rieko Nishimura, Yachiyo Kuwatsuka, Satoru Takada, Masatsugu Tanaka, Shuichi Ota, Nobuaki Dobashi, Etsuko Yamazaki, Asao Hirose, Tohru Murayama, Masahiko Sumi, Shinya Sato, Naoyuki Tange, Yukinori Nakamura, Yuna Katsuoka, Emiko Sakaida, Toyotaka Kawamata, Hiroatsu Iida, Yuichi Shiraishi, Yasuhito Nannya, Seishi Ogawa, Masafumi Taniwaki, Norio Asou, Yoshihiro Hatta, Hitoshi Kiyoi, Itaru Matsumura, Keizo Horibe, Hiroyuki Mano, Tomoki Naoe, Yasushi Miyazaki, Fumihiko Hayakawa
Journal: Blood
Blood (2022) 139 (12): 1850–1862.
https://doi.org/10.1182/blood.2021011921
Published: 2022
Includes: Supplemental data
Journal Articles

Frequent genetic alterations in immune checkpoint–related genes in intravascular large B-cell lymphoma

Kazuyuki Shimada, Kenichi Yoshida, Yasuhiro Suzuki, Chisako Iriyama, Yoshikage Inoue, Masashi Sanada, Keisuke Kataoka, Masaaki Yuge, Yusuke Takagi, Shigeru Kusumoto, Yasufumi Masaki, Takahiko Ito, Yuichiro Inagaki, Akinao Okamoto, Yachiyo Kuwatsuka, Masahiro Nakatochi, Satoko Shimada, Hiroaki Miyoshi, Yuichi Shiraishi, Kenichi Chiba, Hiroko Tanaka, Satoru Miyano, Yusuke Shiozawa, Yasuhito Nannya, Asako Okabe, Kei Kohno, Yoshiko Atsuta, Koichi Ohshima, Shigeo Nakamura, Seishi Ogawa, Akihiro Tomita, Hitoshi Kiyoi
Journal: Blood
Blood (2021) 137 (11): 1491–1502.
https://doi.org/10.1182/blood.2020007245
Published: 2021
Includes: Supplemental data
Journal Articles

Favorable Outcomes of Newly Diagnosed Intravascular Large B-Cell Lymphoma Patients Treated with R-CHOP Combined with High-Dose Methotrexate Plus Intrathecal Chemotherapy: Results from a Multicenter Phase 2 Trial (PRIMEUR-IVL)

Kazuyuki Shimada, MD, Motoko Yamaguchi, MD PhD, Yoshiko Atsuta, MD PhD, Kosei Matsue, MD PhD, Keijiro Sato, MD, Shigeru Kusumoto, MD PhD, Hirokazu Nagai, MD PhD, Jun Takizawa, MD PhD, Noriko Fukuhara, MD PhD, Koji Nagafuji, MD PhD, Kana Miyazaki, MD PhD, Eiichi Ohtsuka, MD, Masataka Okamoto, MD PhD, Yasumasa Sugita, MD PhD, Toshiki Uchida, MD PhD, Satoshi Kayukawa, MD, Atsushi Wake, MD PhD, Daisuke Ennishi, MD PhD, Yukio Kondo, MD, Tohru Izumi, MD, Yoshihiro Kin, MD, Kunihiro Tsukasaki, MD PhD, Daigo Hashimoto, Masaaki Yuge, MD PhD, Atsumi Yanagisawa, Yachiyo Kuwatsuka, MD PhD, Satoko Shimada, MD, Yasufumi Masaki, MD PhD, Nozomi Niitsu, MD PhD, Hitoshi Kiyoi, MD PhD, Ritsuro Suzuki, MD PhD, Takashi Tokunaga, MD PhD, Shigeo Nakamura, MD, Tomohiro Kinoshita, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 350.
https://doi.org/10.1182/blood-2019-126798
Published: 2019
Journal Articles

Prospective Evaluation of Alternative Donor from Unrelated Volunteer Donor and Cord Blood in Adult Acute Leukemia and Myelodysplastic Syndrome: No Difference between Unrelated Donor and Cord Blood

Seitaro Terakura, MD PhD, Tetsuya Nishida, MD PhD, Masashi Sawa, MD PhD, Tomonori Kato, MD PhD, Kotaro Miyao, MD PhD, Yukiyasu Ozawa, MD PhD, Tatsunori Goto, MD, Akio Kohno, MD, Kazutaka Ozeki, MD PhD, Yasushi Onishi, MD PhD, Noriko Fukuhara, MD PhD, Nobuharu Fujii, MD PhD, Hisayuki Yokoyama, MD PhD, Masanobu Kasai, MD PhD, Hiroatsu Iida, MD PhD, Nobuhiro Kanemura, MD PhD, Tomoyuki Endo, MD PhD, Hiroatsu Ago, MD, Makoto Onizuka, MD PhD, Satoshi Iyama, MD PhD, Yuichiro Nawa, MD, Mika Nakamae, MD PhD, Yasuyuki Nagata, MD PhD, Shingo Kurahashi, MD PhD, Yasuo Tomiya, MD, Atsumi Yanagisawa, Ritsuro Suzuki, MD PhD, Yachiyo Kuwatsuka, MD PhD, Yoshiko Atsuta, MD PhD, Koichi Miyamura, MD PhD, Makoto Murata, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4587.
https://doi.org/10.1182/blood-2019-124634
Published: 2019
Journal Articles

Long-term survival following autologous and allogeneic stem cell transplantation for blastic plasmacytoid dendritic cell neoplasm

Clinical Trials & Observations Brief Report
Tomohiro Aoki, Ritsuro Suzuki, Yachiyo Kuwatsuka, Shinichi Kako, Katsuya Fujimoto, Jun Taguchi, Tadakazu Kondo, Kinya Ohata, Toshiro Ito, Yoshimasa Kamoda, Takahiro Fukuda, Tatsuo Ichinohe, Kengo Takeuchi, Koji Izutsu, Junji Suzumiya
Journal: Blood
Blood (2015) 125 (23): 3559–3562.
https://doi.org/10.1182/blood-2015-01-621268
Published: 2015
Journal Articles

Long-Term Survival with High-Dose Chemotherapy Followed By Autologous Stem Cell Transplantation and Allogeneic Hematopoietic Stem Cell Transplantation for Patients with Blastic Plasmacytoid Dendritic Cell Neoplasm: A Retrospective Registry Study from the Japan Society for Hematopoietic Cell Transplantation

Tomohiro Aoki, MD, Ritsuro Suzuki, Yachiyo Kuwatsuka, MDPhD, Shinichi Kako, MD, Katsuya Fujimoto, MD PhD, Jun Taguchi, MD PhD, Tadakazu Kondo, MD PhD, Akiyo Yoshida, MD, Toshiro Ito, MD PhD, Yoshimasa Kamoda, Takahiro Fukuda, MD, Tatsuo Ichinohe, Kengo Takeuchi, MD PhD, Koji Izutsu, Junji Suzumiya
Journal: Blood
Blood (2014) 124 (21): 2560.
https://doi.org/10.1182/blood.V124.21.2560.2560
Published: 2014
Journal Articles

Comparative Outcomes of Chemotherapy with and without HAART for HIV-Related B-Cell Lymphoma: A Meta-Analysis

Matthew J Ehrhardt, MD, Janaki Y Shah, MD, Yachiyo Kuwatsuka, MD, PhD, Sailaja Kamaraju, MD, Jeffrey L Jackson, MD, MPH, Robert Frank Cornell, MD
Journal: Blood
Blood (2013) 122 (21): 4372.
https://doi.org/10.1182/blood.V122.21.4372.4372
Published: 2013
Journal Articles

Treatment with the PI3K/mTOR Inhibitor, NVP-BEZ235, Overcomes Resistance to Imatinib in Quiescent or T315I-Mutated Ph + Leukemia Cells,

Yosuke Minami, MD, PhD, Miho Minami, Nobuaki Fukushima, Yachiyo Kuwatsuka, Tomoki Naoe, MD, PhD
Journal: Blood
Blood (2011) 118 (21): 3488.
https://doi.org/10.1182/blood.V118.21.3488.3488
Published: 2011
Journal Articles

Retention of Slow-Cycling CD34 + cells During Imatinib Treatment and Rapid Decline After 2nd ABL-TKI Treatment in Ph + Leukemia Cells

Yosuke Minami, MD, PhD, Akihiro Abe, Miho Minami, Yachiyo Kuwatsuka, Nobuaki Fukushima, Kunio Kitamura, Junji Hiraga, MD, PhD, Kazuhito Yamamoto, MD, PhD, Catriona Jamieson, Tomoki Naoe, MD, PhD
Journal: Blood
Blood (2011) 118 (21): 641.
https://doi.org/10.1182/blood.V118.21.641.641
Published: 2011
Journal Articles

Biomarkers In Cell Death of Imatinib-Resistant Ph-Leukemia Cells During Treatment with mTOR Inhibitor, Everolimus

Miho Minami, Yosuke Minami, MD, PhD, Yachiyo Kuwatsuka, MD, Hitoshi Kiyoi, MD, PhD, Tomoki Naoe, MD, PhD
Journal: Blood
Blood (2010) 116 (21): 3988.
https://doi.org/10.1182/blood.V116.21.3988.3988
Published: 2010
Journal Articles

Rapid Reduction of Chronic Myeloid Leukemia Stem Cells After Treatment with Second-Generation BCR-ABL Kinase Inhibitors, Dasatinib and Nilotinib

Yosuke Minami, MD, PhD, Akihiro Abe, Yuka Nomura, Miho Minami, Yachiyo Kuwatsuka, Kunio Kitamura, Junji Hiraga, Shinichi Mizuno, Kazuhito Yamamoto, Tomohiro Kajiguchi, Masashi Sawa, Yuichiro Inagaki, Toshiya Yokozawa, Etsuko Aoki, Kazutaka Ozeki, Keisuke Watanabe, Koichi Miyamura, Hitoshi Kiyoi, Tomoki Naoe
Journal: Blood
Blood (2010) 116 (21): 4457.
https://doi.org/10.1182/blood.V116.21.4457.4457
Published: 2010
Journal Articles

Treatment with mTOR Inhibitor, Everolimus (RAD001) Overcomes Resistance to Imatinib In Ph-Leukemia Quiescent Cells.

Yachiyo Kuwatsuka, MD, Yosuke Minami, MD, PhD, Miho Minami, Ryohei Tanizaki, Hitoshi Kiyoi, MD, PhD, Tomoki Naoe, MD, PhD
Journal: Blood
Blood (2010) 116 (21): 1579.
https://doi.org/10.1182/blood.V116.21.1579.1579
Published: 2010
Journal Articles

Treatment with Bortezomib Overcomes Resistance to Imatinib in Ph-Leukemia Quiescent Cells.

Yachiyo Kuwatsuka, MD, Yosuke Minami, MD, PhD, Ryohei Tanizaki, MS, Miho Minami, Akihiro Abe, MD, PhD, Yuka Nomura, Hitoshi Kiyoi, Tomoki Naoe, MD, PhD
Journal: Blood
Blood (2009) 114 (22): 1426.
https://doi.org/10.1182/blood.V114.22.1426.1426
Published: 2009
Journal Articles

Treatment with mTOR Inhibitor, Everolimus (RAD001) Overcomes Resistance to Imatinib in Ph-Leukemia Quiescent or T315I-Mutated Cells.

Yosuke Minami, MD, PhD, Miho Minami, Yachiyo Kuwatsuka, MD, Ryohei Tanizaki, MS, Yuka Nomura, Akihiro Abe, MD, PhD, Hitoshi Kiyoi, MD, PhD, Tomoki Naoe, MD, PhD
Journal: Blood
Blood (2009) 114 (22): 3277.
https://doi.org/10.1182/blood.V114.22.3277.3277
Published: 2009
Journal Articles

Hematopoietic stem cell transplantation for core binding factor acute myeloid leukemia: t(8;21) and inv(16) represent different clinical outcomes

Yachiyo Kuwatsuka, Koichi Miyamura, Ritsuro Suzuki, Masaharu Kasai, Atsuo Maruta, Hiroyasu Ogawa, Ryuji Tanosaki, Satoshi Takahashi, Kyuhei Koda, Kazuhiro Yago, Yoshiko Atsuta, Takashi Yoshida, Hisashi Sakamaki, Yoshihisa Kodera
Journal: Blood
Blood (2009) 113 (9): 2096–2103.
https://doi.org/10.1182/blood-2008-03-145862
Published: 2009
Includes: Supplemental data
Journal Articles

Donor Single Nucleotide Polymorphism in the CCR9 Gene Affects the Incidence of Acute Skin Graft-Versus-Host Disease

Yoshihiro Inamoto, MD, Makoto Murata, MD, PhD, Yachiyo Kuwatsuka, MD, Akane Tsujimura, MD, Kyoko Sugimoto, MD, Taku Oba, MD, Makoto Onizuka, MD, PhD, Seitaro Terakura, MD, PhD, Akira Katsumi, MD, PhD, Koichi Miyamura, MD, PhD, Yoshihisa Kodera, Tomoki Naoe, MD, PhD
Journal: Blood
Blood (2008) 112 (11): 1253.
https://doi.org/10.1182/blood.V112.11.1253.1253
Published: 2008
Journal Articles

Treatment with Hsp90 Inhibitor, 17-AAG Overcomes Resistance to Small Molecule FLT3-Inhibitors in FLT3/ITD-Positive Leukemia Cells Harboring N676K-Mutation.

Yosuke Minami, MD, PhD, Yuka Nomura, Akihiro Abe, MD, PhD, Ryohei Tanizaki, MS, Yachiyo Kuwatsuka, Hitoshi Kiyoi, MD, PhD, Tomoki Naoe, MD
Journal: Blood
Blood (2008) 112 (11): 1619.
https://doi.org/10.1182/blood.V112.11.1619.1619
Published: 2008
Journal Articles

Steroid Therapy Increase Only Adenovirus Infection but Not Cytomegalovirus Infection in Dose Dependent Manner after Hematopoietic Stem Cell Transplantation.

Akane Tsujimura, Koichi Miyamura, Yachiyo Kuwatsuka, Yoshihiro Inamoto, Taku Oba, Seitaro Terakura, Yoshihisa Kodera
Journal: Blood
Blood (2006) 108 (11): 5292.
https://doi.org/10.1182/blood.V108.11.5292.5292
Published: 2006