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Journal Articles

Elongation of MPL Transmembrane Domain Is a Novel Activating-Mutation in Essential Thrombocythemia

Yukiya Yamamoto, MD PhD, Sachiko Iba, Akihiro Abe, MD PhD, Nobuhiko Emi, MDPhD

Blood (2015) 126 (23): 1628.

https://doi.org/10.1182/blood.V126.23.1628.1628

Published: 2015

Journal Articles

A Varicella Outbreak in Diffuse Large B-Cell Lymphoma Patients Receiving Rituximab-Containing Chemotherapy

Akinao Okamoto, MD, Akihiro Abe, MD PhD, Masataka Okamoto, Yoko Inaguma, MD, Tokuda Masutaka, MDPhD, Satoko Morishima, MD, PhD, Masamitsu Yanada, Tadaharu Kanie, MDPhD, Yukiya Yamamoto, MD PhD, Shuichi Mizuta, MD PhD, Yoshiki Akatsuka, MD PhD, Tetsushi Yoshikawa, MDPhD, Nobuhiko Emi, MDPhD

Blood (2014) 124 (21): 5439.

https://doi.org/10.1182/blood.V124.21.5439.5439

Published: 2014

Journal Articles

Wnt Signaling Is Associated with Anti-Apoptosis in the Interaction Between Acute Myeloid Leukemia Cells and Stromal Cells

Yosuke Minami, MD, PhD, Yosuke Niwa, Akihiro Abe, MD, PhD, Fumihiko Hayakawa, MD, PhD, Tomoki Naoe, MD, PhD

Blood (2012) 120 (21): 1366.

https://doi.org/10.1182/blood.V120.21.1366.1366

Published: 2012

Journal Articles

Retention of Slow-Cycling CD34 + cells During Imatinib Treatment and Rapid Decline After 2nd ABL-TKI Treatment in Ph + Leukemia Cells

Yosuke Minami, MD, PhD, Akihiro Abe, Miho Minami, Yachiyo Kuwatsuka, Nobuaki Fukushima, Kunio Kitamura, Junji Hiraga, MD, PhD, Kazuhito Yamamoto, MD, PhD, Catriona Jamieson, Tomoki Naoe, MD, PhD

Blood (2011) 118 (21): 641.

https://doi.org/10.1182/blood.V118.21.641.641

Published: 2011

Journal Articles

PAX5-PML Acts as a Dual Dominant-Negative Form of PAX5 and PML

Shingo Kurahashi, MD, Fumihiko Hayakawa, MD, PhD, Yasuhiko Miyata, MD, PhD, Yosuke Minami, MD, PhD, Akihiro Abe, MD, PhD, Tomoki Naoe, MD, PhD

Blood (2010) 116 (21): 3227.

https://doi.org/10.1182/blood.V116.21.3227.3227

Published: 2010

Journal Articles

Rapid Reduction of Chronic Myeloid Leukemia Stem Cells After Treatment with Second-Generation BCR-ABL Kinase Inhibitors, Dasatinib and Nilotinib

Yosuke Minami, MD, PhD, Akihiro Abe, Yuka Nomura, Miho Minami, Yachiyo Kuwatsuka, Kunio Kitamura, Junji Hiraga, Shinichi Mizuno, Kazuhito Yamamoto, Tomohiro Kajiguchi, Masashi Sawa, Yuichiro Inagaki, Toshiya Yokozawa, Etsuko Aoki, Kazutaka Ozeki, Keisuke Watanabe, Koichi Miyamura, Hitoshi Kiyoi, Tomoki Naoe

Blood (2010) 116 (21): 4457.

https://doi.org/10.1182/blood.V116.21.4457.4457

Published: 2010

Journal Articles

Treatment with Bortezomib Overcomes Resistance to Imatinib in Ph-Leukemia Quiescent Cells.

Yachiyo Kuwatsuka, MD, Yosuke Minami, MD, PhD, Ryohei Tanizaki, MS, Miho Minami, Akihiro Abe, MD, PhD, Yuka Nomura, Hitoshi Kiyoi, Tomoki Naoe, MD, PhD

Blood (2009) 114 (22): 1426.

https://doi.org/10.1182/blood.V114.22.1426.1426

Published: 2009

Journal Articles

Treatment with mTOR Inhibitor, Everolimus (RAD001) Overcomes Resistance to Imatinib in Ph-Leukemia Quiescent or T315I-Mutated Cells.

Yosuke Minami, MD, PhD, Miho Minami, Yachiyo Kuwatsuka, MD, Ryohei Tanizaki, MS, Yuka Nomura, Akihiro Abe, MD, PhD, Hitoshi Kiyoi, MD, PhD, Tomoki Naoe, MD, PhD

Blood (2009) 114 (22): 3277.

https://doi.org/10.1182/blood.V114.22.3277.3277

Published: 2009

Journal Articles

PAX5-PML Acts as a Dual Dominant-Negative Form of Both PAX5 and PML.

Shingo Kurahashi, MD, Fumihiko Hayakawa, MD, PhD, Yasuhiko Miyata, MD, PhD, Yosuke Minami, MD, PhD, Akihiro Abe, MD, PhD, Tomoki Naoe, MD, PhD

Blood (2009) 114 (22): 3070.

https://doi.org/10.1182/blood.V114.22.3070.3070

Published: 2009

Journal Articles

FLT3/ITD Regulates Leukemia Cell Adhesion through α4β1 Integrin and Pyk2 Signaling.

Akira Katsumi, MD, PhD, Hitoshi Kiyoi, Akihiro Abe, MD, PhD, Tomoki Naoe, MD, PhD

Blood (2009) 114 (22): 3108.

https://doi.org/10.1182/blood.V114.22.3108.3108

Published: 2009

Journal Articles

KW-2449, a novel multikinase inhibitor, suppresses the growth of leukemia cells with FLT3 mutations or T315I-mutated BCR/ABL translocation

Yukimasa Shiotsu, Hitoshi Kiyoi, Yuichi Ishikawa, Ryohei Tanizaki, Makiko Shimizu, Hiroshi Umehara, Kenichi Ishii, Yumiko Mori, Kazutaka Ozeki, Yosuke Minami, Akihiro Abe, Hiroshi Maeda, Tadakazu Akiyama, Yutaka Kanda, Yuko Sato, Shiro Akinaga, Tomoki Naoe

Blood (2009) 114 (8): 1607–1617.

https://doi.org/10.1182/blood-2009-01-199307

Published: 2009

Journal Articles

Transformation of E2A-Deficient Pluripotent Progenitors by BCR-ABL Generates Imatinib-Resistant Leukemic Stem Cells.

Yosuke Minami, MD, PhD, Scott A. Stuart, Tomokatsu Ikawa, PhD, Akihiro Abe, MD, PhD, Tomoki Naoe, MD, PhD, Catriona H.M. Jamieson, MD, PhD, Jean Y.J. Wang, PhD

Blood (2008) 112 (11): 1342.

https://doi.org/10.1182/blood.V112.11.1342.1342

Published: 2008

Journal Articles

Retention but Significant Reduction of BCR-ABL Transcript in Hematopoietic Stem Cells in Chronic Myelogenous Leukemia after Imatinib Therapy.

Akihiro Abe, MD, PhD, Yosuke Minami, MD, PhD, Kunio Kitamura, MD, PhD, Fumihiko Hayakawa, MD, PhD, Yuka Nomura, Makoto Murata, MD, PhD, Akira Katsumi, MD, PhD, Hitoshi Kiyoi, MD, PhD, Catriona H.M. Jamieson, MD, PhD, Jean Y.J. Wang, PhD, Tomoki Naoe, MD, PhD

Blood (2008) 112 (11): 2116.

https://doi.org/10.1182/blood.V112.11.2116.2116

Published: 2008

Journal Articles

KW-2449, a Novel Multi-Kinase Inhibitor, Suppresses the Growth of Imatinib-Resistant Ph+ Leukemia Including BCR-ABL/T315I Both in Vitro and in Vivo.

Yukimasa Shiotsu, PhD, Hitoshi Kiyoi, MD, PhD, Ryohei Tanizaki, MD, PhD, Yosuke Minami, MD, PhD, Akihiro Abe, MD, PhD, Yuichi Ishikawa, MD, PhD, Kenichi Ishii, Makiko Shimizu, Yutaka Kanda, PhD, Yuko Sato, MD, PhD, Shiro Akinaga, PhD, Jorge Cortes, MD, Tomoki Naoe, MD, PhD

Blood (2008) 112 (11): 1640.

https://doi.org/10.1182/blood.V112.11.1640.1640

Published: 2008

Journal Articles

Treatment with Hsp90 Inhibitor, 17-AAG Overcomes Resistance to Small Molecule FLT3-Inhibitors in FLT3/ITD-Positive Leukemia Cells Harboring N676K-Mutation.

Yosuke Minami, MD, PhD, Yuka Nomura, Akihiro Abe, MD, PhD, Ryohei Tanizaki, MS, Yachiyo Kuwatsuka, Hitoshi Kiyoi, MD, PhD, Tomoki Naoe, MD

Blood (2008) 112 (11): 1619.

https://doi.org/10.1182/blood.V112.11.1619.1619

Published: 2008

Journal Articles

Gene Alterations and Expression of Hematopoietic Transcription Factors in Pediatric Acute Megakaryoblastic Leukemia (AMKL): A Comparison of Down Syndrome (DS)-Associated AMKL with Non-DS-AMKL.

Asahito Hama, MD, Hiroshi Yagasaki, MD, PhD, Hideki Muramatsu, MD, Nobuhiro Nishio, MD, Akihiro Abe, MD, PhD, Yoshiyuki Takahashi, MD, PhD, Seiji Kojima, MD, PhD

Blood (2008) 112 (11): 2261.

https://doi.org/10.1182/blood.V112.11.2261.2261

Published: 2008

Journal Articles

Clinical and Biological Characteristics of Plasmacytoid Dendritic Cell Lymphoma in Children

Asahito Hama, MD, Hiroshi Yagasaki, MD, PhD, Hideki Muramatsu, MD, Nobuhiro Nishio, MD, Akihiro Abe, MD, PhD, Yoshiyuki Takahashi, MD, PhD, Seiji Kojima, MD, PhD

Blood (2008) 112 (11): 5309.

https://doi.org/10.1182/blood.V112.11.5309.5309

Published: 2008

Journal Articles

Prognostic Implication and Biological Roles of RhoH in Acute Myeloid Leukemia.

Akira Katsumi, MD, PhD, Toshihiro Iwasaki, MD, PhD, Ryohei Tanizaki, MS, Akihiro Abe, MD, PhD, Hitoshi Kiyoi, MD, PhD, Tomoki Naoe, MD, PhD

Blood (2008) 112 (11): 939.

https://doi.org/10.1182/blood.V112.11.939.939

Published: 2008

Journal Articles

Prognostic Implications and Biological Roles of RhoH in Acute Myeloid Leukemia.

Toshihiro Iwasaki, MD, Akira Katsumi, M.D., Ph.D., Hitoshi Kiyoi, M.D., Ph.D., Ryohei Tanizaki, Miki Kobayashi, M.D., Ph.D., Akihiro Abe, M.D., Ph.D., Tadashi Matsushita, M.D., Ph.D., Tomoki Naoe, M.D., Ph.D.

Blood (2007) 110 (11): 4246.

https://doi.org/10.1182/blood.V110.11.4246.4246

Published: 2007

Journal Articles

Peptide-Dependency of Alloreactive T Cell Clones after HLA-Mismatch Hematopoietic Stem Cell Transplantation.

Seitaro Terakura, MD, PhD, Makoto Murata, M.D., Ph.D., Kyoko Sugimoto, M.D., Momoko Suzuki, M.D., Akihiro Abe, M.D., Ph.D., Tomoki Naoe, M.D., Ph.D.

Blood (2007) 110 (11): 3268.

https://doi.org/10.1182/blood.V110.11.3268.3268

Published: 2007

NARROW

Elongation of MPL Transmembrane Domain Is a Novel Activating-Mutation in Essential Thrombocythemia

A Varicella Outbreak in Diffuse Large B-Cell Lymphoma Patients Receiving Rituximab-Containing Chemotherapy

Wnt Signaling Is Associated with Anti-Apoptosis in the Interaction Between Acute Myeloid Leukemia Cells and Stromal Cells

Retention of Slow-Cycling CD34 + cells During Imatinib Treatment and Rapid Decline After 2nd ABL-TKI Treatment in Ph + Leukemia Cells

PAX5-PML Acts as a Dual Dominant-Negative Form of PAX5 and PML

Rapid Reduction of Chronic Myeloid Leukemia Stem Cells After Treatment with Second-Generation BCR-ABL Kinase Inhibitors, Dasatinib and Nilotinib

Treatment with Bortezomib Overcomes Resistance to Imatinib in Ph-Leukemia Quiescent Cells.

Treatment with mTOR Inhibitor, Everolimus (RAD001) Overcomes Resistance to Imatinib in Ph-Leukemia Quiescent or T315I-Mutated Cells.

PAX5-PML Acts as a Dual Dominant-Negative Form of Both PAX5 and PML.

FLT3/ITD Regulates Leukemia Cell Adhesion through α4β1 Integrin and Pyk2 Signaling.

KW-2449, a novel multikinase inhibitor, suppresses the growth of leukemia cells with FLT3 mutations or T315I-mutated BCR/ABL translocation

Transformation of E2A-Deficient Pluripotent Progenitors by BCR-ABL Generates Imatinib-Resistant Leukemic Stem Cells.

Retention but Significant Reduction of BCR-ABL Transcript in Hematopoietic Stem Cells in Chronic Myelogenous Leukemia after Imatinib Therapy.

KW-2449, a Novel Multi-Kinase Inhibitor, Suppresses the Growth of Imatinib-Resistant Ph+ Leukemia Including BCR-ABL/T315I Both in Vitro and in Vivo.

Treatment with Hsp90 Inhibitor, 17-AAG Overcomes Resistance to Small Molecule FLT3-Inhibitors in FLT3/ITD-Positive Leukemia Cells Harboring N676K-Mutation.

Gene Alterations and Expression of Hematopoietic Transcription Factors in Pediatric Acute Megakaryoblastic Leukemia (AMKL): A Comparison of Down Syndrome (DS)-Associated AMKL with Non-DS-AMKL.

Clinical and Biological Characteristics of Plasmacytoid Dendritic Cell Lymphoma in Children

Prognostic Implication and Biological Roles of RhoH in Acute Myeloid Leukemia.

Prognostic Implications and Biological Roles of RhoH in Acute Myeloid Leukemia.

Peptide-Dependency of Alloreactive T Cell Clones after HLA-Mismatch Hematopoietic Stem Cell Transplantation.

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American Society of Hematology

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American Society of Hematology

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