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Journal Articles

Novel Molecular Pathogenesis and Therapeutic Target in Acute Erythroid Leukemia

Blood (2019) 134 (Supplement_1): 914.

https://doi.org/10.1182/blood-2019-129940

Published: 2019

Journal Articles

Genome-Wide Analysis of Non-Coding Alterations in Pan-Myeloid Cancers Using Whole Genome Sequencing

Blood (2018) 132 (Supplement 1): 103.

https://doi.org/10.1182/blood-2018-99-116250

Published: 2018

Journal Articles

Biological Characterization of the U2af1 S34F Mutation in the Pathogenesis of Myelodysplasia

Ayana Kon, MD PhD, Yasuhito Nannya, MD PhD, Masahiro Nakagawa, MD PhD, Keisuke Kataoka, MD PhD, Masashi Sanada, MD PhD, Manabu Nakayama, PhD, Haruhiko Koseki, PhD, Seishi Ogawa, MD PhD

Blood (2018) 132 (Supplement 1): 3080.

https://doi.org/10.1182/blood-2018-99-117453

Published: 2018

Journal Articles

Novel Mechanism of Post-Transcriptional Regulation of PD-L1 Expression By 3'-UTR Binding Proteins

Yasunori Kogure, MD PhD, Keisuke Kataoka, MD PhD, Shungo Adachi, PhD, Yosaku Watatani, MD, Ayana Kon, MD PhD, Kenichi Yoshida, MD PhD, Masahiro Nakagawa, MD PhD, Tomohisa Hatta, PhD, Tohru Natsume, PhD, Seishi Ogawa, MD PhD

Blood (2017) 130 (Supplement 1): 730.

https://doi.org/10.1182/blood.V130.Suppl_1.730.730

Published: 2017

Journal Articles

The Genetic Landscape Of FPD/AML Revealed CDC25C Mutation As a Driver That Promotes Malignant Transformation

Akihide Yoshimi, MD, PhD, Takashi Toya, MD, Masahiro Nakagawa, MD, PhD, Masahito Kawazu, MD, PhD, Yasuhito Nannya, MD, PhD, Motoshi Ichikawa, MD, PhD, Shunya Arai, MD, PhD, Hironori Harada, MD, PhD, Kensuke Usuki, MD, PhD, Yasuhide Hayashi, MD, PhD, Etsuro Ito, MD, PhD, Keita Kirito, MD, PhD, Hideaki Nakajima, MD, PhD, Hiroyuki Mano, MD, PhD, Mineo Kurokawa, MD, PhD

Blood (2013) 122 (21): 739.

https://doi.org/10.1182/blood.V122.21.739.739

Published: 2013

Journal Articles

Inhibition of EZH2 Depletes MLL Fusion Leukemia Stem Cells Through Restoration of p16 Expression

Koki Ueda, Akihide Yoshimi, Masahiro Nakagawa, Satoshi Nishikawa, Victor E Marquez, Keiki Kumano, Mineo Kurokawa, M.D.

Blood (2012) 120 (21): 3510.

https://doi.org/10.1182/blood.V120.21.3510.3510

Published: 2012

Journal Articles

NF-κB/TNF-α Positive Feedback Loop with Active Proteasome Machinery Supports Myeloid Leukemia Initiating Cell Capacity

Yuki Kagoya, Akihide Yoshimi, Shunya Arai, M.D., Keisuke Kataoka, Masahiro Nakagawa, Keiki Kumano, Mineo Kurokawa

Blood (2012) 120 (21): 654.

https://doi.org/10.1182/blood.V120.21.654.654

Published: 2012

Journal Articles

AML1/RUNX1 functions as a cytoplasmic attenuator of NF-κB signaling in the repression of myeloid tumors

Masahiro Nakagawa, Munetake Shimabe, Naoko Watanabe-Okochi, Shunya Arai, Akihide Yoshimi, Akihito Shinohara, Nahoko Nishimoto, Keisuke Kataoka, Tomohiko Sato, Keiki Kumano, Yasuhito Nannya, Motoshi Ichikawa, Yoichi Imai, Mineo Kurokawa

Blood (2011) 118 (25): 6626–6637.

https://doi.org/10.1182/blood-2010-12-326710

Published: 2011

Includes: Supplemental data

Journal Articles

Regulation of Chronic Myelogenous Leukemia Stem Cells by Leukemia Oncogene Evi1

Tomohiko Sato, Susumu Goyama, Keisuke Kataoka, Takako Tsuruta, Masahiro Nakagawa, Keiki Kumano, Katsuyoshi Kumagai, Naoto Kubota, Takashi Kadowaki, Mineo Kurokawa, MD

Blood (2011) 118 (21): 964.

https://doi.org/10.1182/blood.V118.21.964.964

Published: 2011

Journal Articles

BAALC Regulates Hematopoietic Stem Cells Through P53 and Promotes Leukemia with Impaired P53 Function

Sumimasa Nagai, Keiki Kumano, Akihito Shinohara, Masahiro Nakagawa, Motoshi Ichikawa, Mineo Kurokawa

Blood (2011) 118 (21): 48.

https://doi.org/10.1182/blood.V118.21.48.48

Published: 2011

Journal Articles

Loss of AML1/Runx1 accelerates the development of MLL-ENL leukemia through down-regulation of p19 ARF

Nahoko Nishimoto, Shunya Arai, Motoshi Ichikawa, Masahiro Nakagawa, Susumu Goyama, Keiki Kumano, Tsuyoshi Takahashi, Yasuhiko Kamikubo, Yoichi Imai, Mineo Kurokawa

Blood (2011) 118 (9): 2541–2550.

https://doi.org/10.1182/blood-2010-10-315440

Published: 2011

Journal Articles

Evi-1 is a transcriptional target of mixed-lineage leukemia oncoproteins in hematopoietic stem cells

Shunya Arai, Akihide Yoshimi, Munetake Shimabe, Motoshi Ichikawa, Masahiro Nakagawa, Yoichi Imai, Susumu Goyama, Mineo Kurokawa

Blood (2011) 117 (23): 6304–6314.

https://doi.org/10.1182/blood-2009-07-234310

Published: 2011

Includes: Supplemental data

Journal Articles

Evi1 represses PTEN expression and activates PI3K/AKT/mTOR via interactions with polycomb proteins

Akihide Yoshimi, Susumu Goyama, Naoko Watanabe-Okochi, Yumiko Yoshiki, Yasuhito Nannya, Eriko Nitta, Shunya Arai, Tomohiko Sato, Munetake Shimabe, Masahiro Nakagawa, Yoichi Imai, Toshio Kitamura, Mineo Kurokawa

Blood (2011) 117 (13): 3617–3628.

https://doi.org/10.1182/blood-2009-12-261602

Published: 2011

Includes: Supplemental data

Journal Articles

A Critical Role of Reactive Oxygen Species In the Generation of Megakaryocyte-Erythrocyte Progenitor Cells.

Akihito Shinohara, Yoichi Imai, Masahiro Nakagawa, Tsuyoshi Takahashi, MD, PhD, Motoshi Ichikawa, Mineo Kurokawa

Blood (2010) 116 (21): 1605.

https://doi.org/10.1182/blood.V116.21.1605.1605

Published: 2010

Journal Articles

AML1/Runx1 Is a Cytoplasmic Attenuator of NF-Kb Signaling: Implication in Pathogenesis and Targeted Therapy of AML1-Related Leukemia.

Masahiro Nakagawa, Munetake Shimabe, Nahoko Nishimoto, MD, Naoko Watanabe-Okochi, Motoshi Ichikawa, Yasuhito Nannya, Yoichi Imai, Mineo Kurokawa

Blood (2009) 114 (22): 1962.

https://doi.org/10.1182/blood.V114.22.1962.1962

Published: 2009

Journal Articles

Implication of AML1/RUNX1 Function in the Homeostasis and Leukemic Transformation of Hematopoietic Stem Cells.

Motoshi Ichikawa, MD, PhD, Masataka Takeshita, MD,PhD, Susumu Goyama, MD,PhD, Takashi Asai, MD,PhD, Eriko Nitta, MD,PhD, Masahiro Nakagawa, MD,PhD, Masahito Kawazu, MD,PhD, Shigeru Chiba, MD,PhD, Seishi Ogawa, MD,PhD, Mineo Kurokawa, MD,PhD

Blood (2007) 110 (11): 4117.

https://doi.org/10.1182/blood.V110.11.4117.4117

Published: 2007

Journal Articles

Phosphorylation of AML1/Runx1 Is Essential for T Cell Differentiation and Early Hematopoietic Development.

Mayumi Yoshimi, MD, Susumu Goyama, MD, PhD, Masahiro Nakagawa, MD, PhD, Takashi Asai, MD, PhD, Motoshi Ichikawa, MD, PhD, Mineo Kurokawa, MD, PhD

Blood (2007) 110 (11): 2189.

https://doi.org/10.1182/blood.V110.11.2189.2189

Published: 2007

Journal Articles

AML1/Runx1 Negatively Regulates the Number of Quiescent Hematopoietic Stem Cells in Adult Hematopoiesis.

Motoshi Ichikawa, MD, PhD, Takashi Asai, MD, PhD, Masahiro Nakagawa, MD, PhD, Masahito Kawazu, MD, PhD, Susumu Goyama, MD, PhD, Masataka Takeshita, MD, Shigeru Chiba, MD, PhD, Seishi Ogawa, MD, PhD, Mineo Kurokawa, MD, PhD

Blood (2006) 108 (11): 4204.

https://doi.org/10.1182/blood.V108.11.4204.4204

Published: 2006

Journal Articles

AML1/Runx1 rescues Notch1-null mutation-induced deficiency of para-aortic splanchnopleural hematopoiesis

Masahiro Nakagawa, Motoshi Ichikawa, Keiki Kumano, Susumu Goyama, Masahito Kawazu, Takashi Asai, Seishi Ogawa, Mineo Kurokawa, Shigeru Chiba

Blood (2006) 108 (10): 3329–3334.

https://doi.org/10.1182/blood-2006-04-019570

Published: 2006

Journal Articles

The transcriptionally active form of AML1 is required for hematopoietic rescue of the AML1 -deficient embryonic para-aortic splanchnopleural (P-Sp) region

Susumu Goyama, Yuko Yamaguchi, Yoichi Imai, Masahito Kawazu, Masahiro Nakagawa, Takashi Asai, Keiki Kumano, Kinuko Mitani, Seishi Ogawa, Shigeru Chiba, Mineo Kurokawa, Hisamaru Hirai

Blood (2004) 104 (12): 3558–3564.

https://doi.org/10.1182/blood-2004-04-1535

Published: 2004

NARROW

Novel Molecular Pathogenesis and Therapeutic Target in Acute Erythroid Leukemia

Genome-Wide Analysis of Non-Coding Alterations in Pan-Myeloid Cancers Using Whole Genome Sequencing

Biological Characterization of the U2af1 S34F Mutation in the Pathogenesis of Myelodysplasia

Novel Mechanism of Post-Transcriptional Regulation of PD-L1 Expression By 3'-UTR Binding Proteins

The Genetic Landscape Of FPD/AML Revealed CDC25C Mutation As a Driver That Promotes Malignant Transformation

Inhibition of EZH2 Depletes MLL Fusion Leukemia Stem Cells Through Restoration of p16 Expression

NF-κB/TNF-α Positive Feedback Loop with Active Proteasome Machinery Supports Myeloid Leukemia Initiating Cell Capacity

AML1/RUNX1 functions as a cytoplasmic attenuator of NF-κB signaling in the repression of myeloid tumors

Regulation of Chronic Myelogenous Leukemia Stem Cells by Leukemia Oncogene Evi1

BAALC Regulates Hematopoietic Stem Cells Through P53 and Promotes Leukemia with Impaired P53 Function

Loss of AML1/Runx1 accelerates the development of MLL-ENL leukemia through down-regulation of p19 ARF

Evi-1 is a transcriptional target of mixed-lineage leukemia oncoproteins in hematopoietic stem cells

Evi1 represses PTEN expression and activates PI3K/AKT/mTOR via interactions with polycomb proteins

A Critical Role of Reactive Oxygen Species In the Generation of Megakaryocyte-Erythrocyte Progenitor Cells.

AML1/Runx1 Is a Cytoplasmic Attenuator of NF-Kb Signaling: Implication in Pathogenesis and Targeted Therapy of AML1-Related Leukemia.

Implication of AML1/RUNX1 Function in the Homeostasis and Leukemic Transformation of Hematopoietic Stem Cells.

Phosphorylation of AML1/Runx1 Is Essential for T Cell Differentiation and Early Hematopoietic Development.

AML1/Runx1 Negatively Regulates the Number of Quiescent Hematopoietic Stem Cells in Adult Hematopoiesis.

AML1/Runx1 rescues Notch1-null mutation-induced deficiency of para-aortic splanchnopleural hematopoiesis

The transcriptionally active form of AML1 is required for hematopoietic rescue of the AML1 -deficient embryonic para-aortic splanchnopleural (P-Sp) region

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American Society of Hematology

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American Society of Hematology

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