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Journal Articles

ctDNA improves prognostic prediction for patients with relapsed/refractory MM receiving ixazomib, lenalidomide, and dexamethasone

Yasunori Kogure, Hiroshi Handa, Yuta Ito, Masaki Ri, Yuichi Horigome, Masaki Iino, Yoriko Harazaki, Takahiro Kobayashi, Masahiro Abe, Tadao Ishida, Shigeki Ito, Hiromi Iwasaki, Junya Kuroda, Hirohiko Shibayama, Kazutaka Sunami, Hiroyuki Takamatsu, Hideto Tamura, Toshiaki Hayashi, Kiwamu Akagi, Tomohiro Shinozaki, Takahiro Yoshida, Ikuo Mori, Shinsuke Iida, Takahiro Maeda, Keisuke Kataoka
Journal: Blood
Blood (2024) 143 (23): 2401–2413.
https://doi.org/10.1182/blood.2023022540
Published: 2024
Includes: Supplemental data
Journal Articles

NGS Profile and the Mathematical Prediction Model for Venetoclax Combination Therapy in HM-Screen-Japan 02 Study

Tomoaki Ueda, Kentaro Fukushima, Naoki Hosen, Sunggi Chi, Hiroshi Haeno, Goichi Yoshimoto, Hironori Arai, Daisuke Ikeda, Kensuke Usuki, Naoto Takahashi, Naoko Hosono, Takahiro Yamauchi, Takeshi Kondo, Kazuhito Yamamoto, Junya Kuroda, Yosuke Minami
Journal: Blood
Blood (2023) 142 (Supplement 1): 5761.
https://doi.org/10.1182/blood-2023-180339
Published: 2023
Journal Articles

TAS0612, a Triple Inhibitor for RSK, AKT, and S6K, Is a Promising Anti-Myeloma Agent Regardless of Types of Cytogenetic/Genetic Abnormality

Haruya Okamoto, Shinsuke Mizutani, Taku Tsukamoto, Yoko Katsuragawa-Taminishi, Reiko Isa, Kentaro Mizuhara, Ayako Muramatsu, Yuka Kawaji-Kanayama, Takahiro Fujino, Yuji Shimura, Junya Kuroda
Journal: Blood
Blood (2023) 142 (Supplement 1): 3313.
https://doi.org/10.1182/blood-2023-174157
Published: 2023
Journal Articles

The Universal Antitumor Activity of TAS0612, a Triple Inhibitor for RSK, AKT, and S6K, in B-Cell Lymphomas Regardless of Disease Subtype

Yoko Katsuragawa-Taminishi, Shinsuke Mizutani, Yuka Kawaji-Kanayama, Akio Onishi, Haruya Okamoto, Reiko Isa, Kentaro Mizuhara, Ayako Muramatsu, Takahiro Fujino, Taku Tsukamoto, Yuji Shimura, Masafumi Taniwaki, Aya Miyagawa-Hayashino, Eiichi Konishi, Junya Kuroda
Journal: Blood
Blood (2023) 142 (Supplement 1): 7135.
https://doi.org/10.1182/blood-2023-173485
Published: 2023
Journal Articles

Final Analysis of the Randomized Phase II/III Study of Standard R-CHOP Versus CHOP Combined with Dose-Dense Weekly Rituximab for DLBCL: JCOG0601

Ken Ohmachi, Tomohiro Kinoshita, Dai Maruyama, Gakuto Ogawa, Yusuke Sano, Nobuhiko Yamauchi, Noriko Fukuhara, Toshiki Uchida, Kazuhito Yamamoto, Kana Miyazaki, Norifumi Tsukamoto, Shinsuke Iida, Isao Yoshida, Yasuhiro Suzuki, Yasufumi Masaki, Tohru Murayama, Yoshihiro Yakushijin, Youko Suehiro, Kisato Nosaka, Nobuaki Dobashi, Junya Kuroda, Wataru Munakata, Kiyoshi Ando, Kenichi Ishizawa, Michinori Ogura, Tadashi Yoshino, Tomomitsu Hotta, Kunihiro Tsukasaki, Kensei Tobinai, Hirokazu Nagai
Journal: Blood
Blood (2023) 142 (Supplement 1): 1724.
https://doi.org/10.1182/blood-2023-178551
Published: 2023
Journal Articles

The Activation Status of RSK2, but Not PDPK1 and AKT, Associates with the Prognosis of Diffuse Large B Cell Lymphoma

Akio Onishi, Aya Miyagawa-Hayashino, Kentaro Mizuhara, Ayako Muramatsu, Haruya Okamoto, Yuka Kawaji-Kanayama, Yoko Katsuragawa-Taminishi, Takahiro Fujino, Taku Tsukamoto, Shinsuke Mizutani, Yuji Shimura, Eiichi Konishi, Junya Kuroda
Journal: Blood
Blood (2023) 142 (Supplement 1): 4390.
https://doi.org/10.1182/blood-2023-184365
Published: 2023
Journal Articles

A Phase 1 Trial of OPB-111077 in Combination with Bendamustine (B) and Rituximab (R) in Patients with Relapsed or Refractory (R/R) Diffuse Large B-Cell Lymphoma (DLBCL): Preliminary Results of Dose-Escalation Stage

Tomomi Toubai, Junya Kuroda, Youko Suehiro, Yuko Mishima, Kazutaka Sunami, Koji Kato, Nobuhiko Uoshima, Takahiro Kumode, Ai Ota, Kaori Mitsuki, Daisuke Yokota, Yuri Sano, Yasuhito Terui
Journal: Blood
Blood (2023) 142 (Supplement 1): 4464.
https://doi.org/10.1182/blood-2023-179716
Published: 2023
Journal Articles

An Open-Label, Multicenter, Single-Arm, Phase I Dose Escalation Study of OP-2100, an Orally Bioavailable Prodrug of Decitabine, for Patients with Relapsed or Refractory Higher-Risk Myelodysplastic Syndromes and Chronic Myelomonocytic Leukemia

Shinya Kimura, Kensuke Usuki, Tatsuo Ichinohe, Takayuki Ikezoe, Junya Kuroda, Senji Kasahara, Sho Okamoto, Hiromitsu Iizuka, Hiroshi Ureshino, Tatsuro Watanabe, Tokihiro Ro, Kosuke Endo, Yuka Kagawa, Yuki Kurahashi, Toshiki Naito, Takahiro Yamauchi
Journal: Blood
Blood (2023) 142 (Supplement 1): 6466.
https://doi.org/10.1182/blood-2023-173174
Published: 2023
Journal Articles

Nutritional and Cytogenetic Assessment Predicts Favorable Response to Azacitidine Monotherapy for Myelodysplastic Syndromes

Haruya Okamoto, Yu Inoue, Akihiro Miyashita, Yuka Kawaji-Kanayama, Shotaro Chinen, Takahiro Fujino, Taku Tsukamoto, Yuji Shimura, Shinsuke Mizutani, Hiroto Kaneko, Saeko Kuwahara, Shin-ichi Fuchida, Daichi Nishiyama, Koichi Hirakawa, Junya Kuroda
Journal: Blood
Blood (2022) 140 (Supplement 1): 12321–12322.
https://doi.org/10.1182/blood-2022-157863
Published: 2022
Journal Articles

Final Analysis of JCOG0203 for Advanced-Stage Indolent B-Cell Lymphoma 15 Years after the End of Enrollment: Pooled Analysis of Arms a and B for Follicular Lymphoma

Takashi Watanabe, Kensei Tobinai, Ｍasashi Wakabayashi, Dai Maruyama, Kazuhito Yamamoto, Nobuko Kubota, Kazuyuki Shimada, Kohsuke Asagoe, Motoko Yamaguchi, Kiyoshi Ando, Michinori Ogura, Junya Kuroda, Youko Suehiro, Yoshihiro Matsuno, Kunihiro Tsukasaki, Hirokazu Nagai
Journal: Blood
Blood (2022) 140 (Supplement 1): 3615–3617.
https://doi.org/10.1182/blood-2022-159967
Published: 2022
Journal Articles

Mutational Analysis of DNMT3A Improves the Prognostic Stratification Using NPM1 / FLT3 -ITD Genotypes in Patients with Acute Myeloid Leukemia

Atsushi Marumo, Satoshi Wakita, Kaoru Morita, Shinichi Kako, Takashi Toya, Yuho Najima, Noriko Doki, Junya Kanda, Junya Kuroda, Shin-Ichiro Mori, Atsushi Satake, Kensuke Usuki, Toshimitsu Ueki, Nobuhiko Uoshima, Yutaka Kobayashi, Eri Kawata, Kazutaka Nakayama, Yuhei Nagao, Katsuhiro Shono, Motoharu Shibusawa, Jiro Tadokoro, Masao Hagihara, Hitoji Uchiyama, Naoyuki Uchida, Yasushi Kubota, Shinya Kimura, Hisao Nagoshi, Tatsuo Ichinohe, Saiko Kurosawa, Sayuri Motomura, Hashimoto Akiko, Hideharu Muto, Eriko Sato, Masao Ogata, Kenjiro Mitsuhashi, Jun Ando, Haruko Tashiro, Masahiro Sakaguchi, Shunsuke Yui, Kunihito Arai, Tomoaki Kitano, Miho Miyata, Takahiro Fukuda, Yoshinobu Kanda, Hiroki Yamaguchi
Journal: Blood
Blood (2022) 140 (Supplement 1): 8914–8916.
https://doi.org/10.1182/blood-2022-158686
Published: 2022
Journal Articles

Mir-106a-5p and Mir-146a-5p Delivered By Tumor-Derived Exosomes Promote the Induction of Myeloid-Derived Suppressor Cells from Normal Peripheral Blood Mononuclear Cells in Multiple Myeloma

Kentaro Mizuhara, Yuji Shimura, Taku Tsukamoto, Akinori Kanai, Saeko Kuwahara-Ota, Junko Yamaguchi, Ayako Muramatsu, Haruya Okamoto, Yoko Katsuragawa-Taminishi, Yuka Kawaji-Kanayama, Reiko Isa, Shinsuke Mizutani, Toshiya Inaba, Junya Kuroda
Journal: Blood
Blood (2022) 140 (Supplement 1): 9949–9950.
https://doi.org/10.1182/blood-2022-160408
Published: 2022
Journal Articles

Genomic Analysis of NPM1 Mutation and KMT2A ( MLL )-Rearrangement/Amplification in Japanese Patients with Acute Myeloid Leukemia: Hematologic Malignancies (HM)-Screen-Japan 01

SungGi Chi, Kentaro Fukushima, Hirohiko Shibayama, Naoko Hosono, Takahiro Yamauchi, Seiichiro Katagiri, Akihiko Gotoh, Motoki Eguchi, Takanobu Morishita, Reiki Ogasawara, Takeshi Kondo, Masamitsu Yanada, Kazuhito Yamamoto, Tsutomu Kobayashi, Junya Kuroda, Yoshimasa Kamoda, Kensuke Usuki, Yoshikazu Utsu, Nobuyuki Aotsuka, Makoto Yoshimitsu, Kenji Ishitsuka, Yasuyuki Nagata, Takaaki Ono, Naohito Fujishima, Naoto Takahashi, Hiroto Horiguchi, Satoshi Iyama, Makoto Nakamura, Kensuke Kojima, Kaoru Yamamoto, Yukinori Nakamura, Suguru Fukuhara, Koji Izutsu, Nobuhiko Yamauchi, Junichiro Yuda, Yosuke Minami
Journal: Blood
Blood (2021) 138 (Supplement 1): 4460.
https://doi.org/10.1182/blood-2021-149425
Published: 2021
Journal Articles

Properties and Distribution of IDH-1/2 Mutations in Acute Myeloid Leukemia By the Comprehensive Genomic Analysis

Satoshi Uchiyama, Nakamura Hirotaka, SungGi Chi, Kentaro Fukushima, Hirohiko Shibayama, Naoko Hosono, Takahiro Yamauchi, Seiichiro Katagiri, Akihiko Gotoh, Motoki Eguchi, Takanobu Morishita, Reiki Ogasawara, Takeshi Kondo, Masamitsu Yanada, Kazuhito Yamamoto, Tsutomu Kobayashi, Junya Kuroda, Kensuke Usuki, Nobuyuki Aotsuka, Makoto Yoshimitsu, Kenji Ishitsuka, Takaaki Ono, Naoto Takahashi, Satoshi Iyama, Makoto Nakamura, Yukinori Nakamura, Suguru Fukuhara, Koji Izutsu, Nobuhiko Yamauchi, Junichiro Yuda, Yosuke Minami
Journal: Blood
Blood (2021) 138 (Supplement 1): 4447.
https://doi.org/10.1182/blood-2021-149801
Published: 2021
Journal Articles

Genomic Analysis Focusing on RUNX1-RUNX1T1 in Japanese Patients with AML: HM-Screen-Japan 01

Seiichiro Katagiri, Daigo Akahane, Akihiko Gotoh, SungGi Chi, Kentaro Fukushima, Hirohiko Shibayama, Naoko Hosono, Takahiro Yamauchi, Motoki Eguchi, Takanobu Morishita, Reiki Ogasawara, Takeshi Kondo, Masamitsu Yanada, Kazuhito Yamamoto, Tsutomu Kobayashi, Junya Kuroda, Kensuke Usuki, Yoshikazu Utsu, Nobuyuki Aotsuka, Makoto Yoshimitsu, Kenji Ishitsuka, Takaaki Ono, Naoto Takahashi, Satoshi Iyama, Makoto Nakamura, Yukinori Nakamura, Koji Izutsu, Nobuhiko Yamauchi, Junichiro Yuda, Yosuke Minami
Journal: Blood
Blood (2021) 138 (Supplement 1): 4464.
https://doi.org/10.1182/blood-2021-148492
Published: 2021
Journal Articles

Hematologic Malignancies (HM)-Screen-Japan 01: A Mutation Profiling Multicenter Study on Patients with Acute Myeloid Leukemia

Naoko Hosono, Takahiro Yamauchi, SungGi Chi, Kentaro Fukushima, Hirohiko Shibayama, Seiichiro Katagiri, Akihiko Gotoh, Motoki Eguchi, Takanobu Morishita, Reiki Ogasawara, Takeshi Kondo, Masamitsu Yanada, Kazuhito Yamamoto, Tsutomu Kobayashi, Junya Kuroda, Kensuke Usuki, Yoshikazu Utsu, Nobuyuki Aotsuka, Makoto Yoshimitsu, Kenji Ishitsuka, Takaaki Ono, Naoto Takahashi, Satoshi Iyama, Makoto Nakamura, Yukinori Nakamura, Suguru Fukuhara, Koji Izutsu, Nobuhiko Yamauchi, Junichiro Yuda, Yosuke Minami
Journal: Blood
Blood (2021) 138 (Supplement 1): 4457.
https://doi.org/10.1182/blood-2021-149960
Published: 2021
Journal Articles

Clinical Significance of FLT3 Mutations in a Comprehensive NGS Multicenter Study of AML: HM-Screen-Japan 01

Kentaro Fukushima, Hirohiko Shibayama, SungGi Chi, Naoko Hosono, Takahiro Yamauchi, Seiichiro Katagiri, Akihiko Gotoh, Motoki Eguchi, Takanobu Morishita, Reiki Ogasawara, Takeshi Kondo, Masamitsu Yanada, Kazuhito Yamamoto, Tsutomu Kobayashi, Junya Kuroda, Yoshimasa Kamoda, Kensuke Usuki, Yoshikazu Utsu, Nobuyuki Aotsuka, Makoto Yoshimitsu, Kenji Ishitsuka, Takaaki Ono, Naoto Takahashi, Satoshi Iyama, Makoto Nakamura, Yukinori Nakamura, Suguru Fukuhara, Koji Izutsu, Nobuhiko Yamauchi, Junichiro Yuda, Yosuke Minami
Journal: Blood
Blood (2021) 138 (Supplement 1): 2313.
https://doi.org/10.1182/blood-2021-146796
Published: 2021
Journal Articles

Clinical Outcomes of Elderly Patients with Advanced-Stage Classic Hodgkin Lymphoma Who Received an ABVD Regimen: A Multi-Center Retrospective Study in Japan (HORIZON study)

Shinichi Makita, Shigeru Kusumoto, Akiko Miyagi Maeshima, Hiroya Hashimoto, Hideki Tsujimura, Toshiki Uchida, Hiroaki Inoue, Eiichi Ohtsuka, Mitsutoshi Kurosawa, Nobuyuki Takayama, Eiju Negoro, Yasuhiro Suzuki, Junya Kuroda, Kayoko Murayama, Naoki Takahashi, Kazuyuki Shimada, Masataka Okamoto, Masanori Makita, Hiromi Iwasaki, Masahiro Yoshida, Naoko Asano, Jun-ichi Tamaru, Dai Maruyama, Motoko Yamaguchi, Hirokazu Nagai
Journal: Blood
Blood (2021) 138 (Supplement 1): 2451.
https://doi.org/10.1182/blood-2021-146340
Published: 2021
Journal Articles

Very Low-Dose Dasatinib Is a Safe and Effective Therapy for Elderly Patients with Newly-Diagnosed Chronic-Phase Chronic Myeloid Leukemia: Results from the Davlec Study, a Single-Arm, Multicenter, Phase 2 Trial

Takashi Kumagai, Kazunori Murai, Hiroshi Ureshino, Hideo Tanaka, Kaichi Nishiwaki, Satoshi Wakita, Koiti Inokuchi, Toshihiro Fukushima, Chikashi Yoshida, Masayuki Mita, Nobuhiko Uoshima, Toru Kiguchi, Jun Aoki, Satoshi Kimura, Kaori Karimata, Kensuke Usuki, Joji Shimono, Yoshiaki Chinen, Junya Kuroda, Yasufumi Matsuda, Kensuke Nakao, Takaaki Ono, Katsumichi Fujimaki, Hirohiko Shibayama, Chisaki Mizumoto, Tomoharu Takeoka, Katsuhiro Io, Takeshi Kondo, Masatomo Miura, Yosuke Minami, Takayuki Ikezoe, Jun Imagawa, Ayako Takamori, Atsushi Kawaguchi, Junichi Sakamoto, Shinya Kimura
Journal: Blood
Blood (2021) 138 (Supplement 1): 3601.
https://doi.org/10.1182/blood-2021-149483
Published: 2021
Journal Articles

Interim Analysis of Hematologic Malignancies (HM)-Screen-Japan 01: A Mutation Profiling Multicenter Study of Patients with AML

Kenichi Miyamoto, MD, Kentaro Fukushima, MD PhD, SungGi Chi, MD PhD, Hirohiko Shibayama, MD PhD, Naoko Hosono, MD PhD, Takahiro Yamauchi, MD PhD, Seiichiro Katagiri, MDPhD, Akihiko Gotoh, MD PhD, Takanobu Morishita, MD, PhD, Masamitsu Yanada, MD PhD, Kazuhito Yamamoto, MD PhD, Naohito Fujishima, MD PhD, Naoto Takahashi, MD PhD, Reiki Ogasawara, MDPhD, Takeshi Kondo, MD PhD, Yoshikazu Utsu, MD PhD, Nobuyuki Aotsuka, MD PhD, Kensuke Usuki, MD PhD, Takaaki ONO, MD PhD, Tsutomu Kobayashi, MD PhD, Junya Kuroda, MD PhD, Hiroto Horiguchi, MDPhD, Satoshi Iyama, MD PhD, Suguru Fukuhara, MD PhD, Koji Izutsu, MD PhD, Makoto Nakamura, MD PhD, Kensuke Kojima, MD PhD, Yosuke Minami, MDPhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 2–3.
https://doi.org/10.1182/blood-2020-139147
Published: 2020