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Toshiaki Hayashi
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Journal Articles

ctDNA improves prognostic prediction for patients with relapsed/refractory MM receiving ixazomib, lenalidomide, and dexamethasone

Yasunori Kogure, Hiroshi Handa, Yuta Ito, Masaki Ri, Yuichi Horigome, Masaki Iino, Yoriko Harazaki, Takahiro Kobayashi, Masahiro Abe, Tadao Ishida, Shigeki Ito, Hiromi Iwasaki, Junya Kuroda, Hirohiko Shibayama, Kazutaka Sunami, Hiroyuki Takamatsu, Hideto Tamura, Toshiaki Hayashi, Kiwamu Akagi, Tomohiro Shinozaki, Takahiro Yoshida, Ikuo Mori, Shinsuke Iida, Takahiro Maeda, Keisuke Kataoka
Journal: Blood
Blood (2024) 143 (23): 2401–2413.
https://doi.org/10.1182/blood.2023022540
Published: 2024
Includes: Supplemental data
Journal Articles

Phase II Study of the Bortezomib-Melphalan-Prednisolone Induction Therapy Followed By Lenalidomide-Plus-Dexamethasone Consolidation and Lenalidomide Maintenance in Non-Transplant Eligible Patients with Newly Diagnosed Symptomatic Multiple Myeloma (CANDLE trial)

Tadao Ishida, MD, Shuji Ozaki, MD PhD, Hideo Kimura, MD PhD, Koumei Kubo, MD, Kazutaka Sunami, MD PhD, Naoki Takezako, MD PhD, Hiroyuki Fujita, MD PhD, Toshiaki Hayashi, MD PhD, Toru Kiguchi, MD PhD, Takeshi Kobayashi, MD, Satoshi Yamamoto, MD PhD, Hiroyuki Takamatsu, MD PhD, Hiroshi Kosugi, MD PhD, Kensuke Ohta, MD PhD, Rika Sakai, MD PhD, Hiroshi Handa, MD PhDChief Division, Takashi Hisatomi, MD PhD, Yu Abe, MD, Ko Sasaki, MD PhD, Eijiro Omoto, MD PhD, Hirokazu Murakami, MDPhDProf, Kazuyuki Shimizu, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3121.
https://doi.org/10.1182/blood.V130.Suppl_1.3121.3121
Published: 2017
Journal Articles

Addition of Bortezomib to Melphalan Plus Dexamethasone Provides Rapid Response in AL Amyloidosis

Toshiaki Hayashi, MD PhD, Tetsuyuki Igarashi, MD, Hiroshi Ikeda, MD PhD, Mitsufumi Nishio, MD PhD, Tadao Ishida, MD PhD, Yasuhisa Shinomura, MD PhD
Journal: Blood
Blood (2014) 124 (21): 5766.
https://doi.org/10.1182/blood.V124.21.5766.5766
Published: 2014
Journal Articles

B Type Natriuretic Peptide (BNP) Less Than 200 Pg/Ml Represents Good Candidate For High Dose Melphalan and Predicts Longer Survival In Systemic Light Chain Amyloidosis

Toshiaki Hayashi, M.D., Ph.D., Hiroshi Ikeda, M.D., Ph.D., Yuka Aoki, M.D., Ph.D., Yumiko Maruyama, M.D., Ph.D., Tadao Ishida, M.D., Ph.D., Yasuhisa Shinomura, M.D., Ph.D.
Journal: Blood
Blood (2013) 122 (21): 5523.
https://doi.org/10.1182/blood.V122.21.5523.5523
Published: 2013
Journal Articles

Stroma cells and Monocytes make Multiple Myeloma Cells Active In Bone Marrow Microenviroment

Hiroshi Ikeda, MD, PhD, Tadao Ishida, M.D., Ph.D., Toshiaki Hayashi, M.D., Ph.D., Yuka Aoki, M.D., Ph.D., Yasuhisa Shinomura, M.D., Ph.D.
Journal: Blood
Blood (2013) 122 (21): 5333.
https://doi.org/10.1182/blood.V122.21.5333.5333
Published: 2013
Journal Articles

The Relationship of Myeloma Cells, Stromal Cells and Monocytes Under Bone Marrow Microenvironment

Hiroshi Ikeda, MD, PhD, Yuka Aoki, MD, Nasanori Nojima, MD, PhD, Hiroshi Yasui, MD, PhD, Toshiaki Hayashi, MD, PhD, Tadao Ishida, MD, PhD
Journal: Blood
Blood (2012) 120 (21): 4987.
https://doi.org/10.1182/blood.V120.21.4987.4987
Published: 2012
Journal Articles

TGF-β Receptor I Kinase Inhibitor Downregulates Cytokine Secretion and Multiple Myeloma Cell Growth in the Bone Marrow Microenvironment.

Toshiaki Hayashi, MD, PhD, Teru Hideshima, MD, PhD, Klaus Podar, MD, PhD, Paul Richardson, MD, Olivier Munoz, MD, Makoto Hamasaki, MD, PhD, Kenji Ishitsuka, MD, PhD, Hiroshi Yasui, MD, PhD, Alison Murphy, PhD, Glenn McEnroe, PhD, Sarvajit Chakravarty, PhD, Sundeep Dugar, PhD, Linda S. Higgins, PhD, Dharminder Chauhan, PhD, Kenneth C. Anderson, MD
Journal: Blood
Blood (2004) 104 (11): 2355.
https://doi.org/10.1182/blood.V104.11.2355.2355
Published: 2004
Journal Articles

Atiprimod (N-N-diethl-8,8-dipropyl-2-azaspiro [4.5] decane-2-propanamine) Inhibits Myeloma in Vivo.

Makoto Hamasaki, Teru Hideshima, Pierfrancesco Tassone, Paola Neli, Kenji Ishitsuka, Masaharu Akiyama, Toshiaki Hayashi, Hiroshi Yasui, Norihiko Shiraishi, Dharminder Chauhan, Constantine Mitsiades, Klaus Podar, Deepak Gupta, Donald H. Picker, Gary S. Jacob, Paul G. Richardson, Nikhil C. Munshi, Kenneth C. Anderson
Journal: Blood
Blood (2004) 104 (11): 2401.
https://doi.org/10.1182/blood.V104.11.2401.2401
Published: 2004
Journal Articles

GW654652, the pan-inhibitor of VEGF receptors, blocks the growth and migration of multiple myeloma cells in the bone marrow microenvironment

Klaus Podar, Laurence P. Catley, Yu-Tzu Tai, Reshma Shringarpure, Pedro Carvalho, Toshiaki Hayashi, Renate Burger, Robert L. Schlossman, Paul G. Richardson, Lini N. Pandite, Rakesh Kumar, Teru Hideshima, Dharminder Chauhan, Kenneth C. Anderson
Journal: Blood
Blood (2004) 103 (9): 3474–3479.
https://doi.org/10.1182/blood-2003-10-3527
Published: 2004
Journal Articles

Hsp27 inhibits release of mitochondrial protein Smac in multiple myeloma cells and confers dexamethasone resistance

Dharminder Chauhan, Guilan Li, Teru Hideshima, Klaus Podar, Constantine Mitsiades, Nicholas Mitsiades, Laurence Catley, Yu Tzu Tai, Toshiaki Hayashi, Reshma Shringarpure, Renate Burger, Nikhil Munshi, Yasuyuki Ohtake, Satya Saxena, Kenneth C. Anderson
Journal: Blood
Blood (2003) 102 (9): 3379–3386.
https://doi.org/10.1182/blood-2003-05-1417
Published: 2003
Journal Articles

Ex vivo induction of multiple myeloma–specific cytotoxic T lymphocytes

Toshiaki Hayashi, Teru Hideshima, Masaharu Akiyama, Noopur Raje, Paul Richardson, Dharminder Chauhan, Kenneth C. Anderson
Journal: Blood
Blood (2003) 102 (4): 1435–1442.
https://doi.org/10.1182/blood-2002-09-2828
Published: 2003
Journal Articles

Molecular mechanisms mediating antimyeloma activity of proteasome inhibitor PS-341

Teru Hideshima, Constantine Mitsiades, Masaharu Akiyama, Toshiaki Hayashi, Dharminder Chauhan, Paul Richardson, Robert Schlossman, Klaus Podar, Nikhil C. Munshi, Nicholas Mitsiades, Kenneth C. Anderson
Journal: Blood
Blood (2003) 101 (4): 1530–1534.
https://doi.org/10.1182/blood-2002-08-2543
Published: 2003
Journal Articles

Targeting p38 MAPK inhibits multiple myeloma cell growth in the bone marrow milieu

Brief Report
Teru Hideshima, Masaharu Akiyama, Toshiaki Hayashi, Paul Richardson, Robert Schlossman, Dharminder Chauhan, Kenneth C. Anderson
Journal: Blood
Blood (2003) 101 (2): 703–705.
https://doi.org/10.1182/blood-2002-06-1874
Published: 2003