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Journal Articles

Loss of GABARAP mediates resistance to immunogenic chemotherapy in multiple myeloma

Annamaria Gulla, Eugenio Morelli, Megan Johnstone, Marcello Turi, Mehmet K. Samur, Cirino Botta, Selma Cifric, Pietro Folino, Delaney Vinaixa, Francesca Barello, Cole Clericuzio, Vanessa Katia Favasuli, Domenico Maisano, Srikanth Talluri, Rao Prabhala, Giada Bianchi, Mariateresa Fulciniti, Kenneth Wen, Keiji Kurata, Jiye Liu, Johany Penailillo, Alberto Bragoni, Anna Sapino, Paul G. Richardson, Dharminder Chauhan, Ruben D. Carrasco, Teru Hideshima, Nikhil C. Munshi, Kenneth C. Anderson
Journal: Blood
Blood (2024) 143 (25): 2612–2626.
https://doi.org/10.1182/blood.2023022777
Published: 2024
Includes: Supplemental data
Journal Articles

Ubiquitin receptor PSMD4/Rpn10 is a novel therapeutic target in multiple myeloma

Ting Du, Yan Song, Arghya Ray, Xueping Wan, Yao Yao, Mehmet K. Samur, Chen Shen, Johany Penailillo, Tomasz Sewastianik, Yu-Tzu Tai, Mariateresa Fulciniti, Nikhil C. Munshi, Hao Wu, Ruben D. Carrasco, Dharminder Chauhan, Kenneth C. Anderson
Journal: Blood
Blood (2023) 141 (21): 2599–2614.
https://doi.org/10.1182/blood.2022017897
Published: 2023
Includes: Supplemental data
Journal Articles

A MIR17HG-derived long noncoding RNA provides an essential chromatin scaffold for protein interaction and myeloma growth

Eugenio Morelli, Mariateresa Fulciniti, Mehmet K. Samur, Caroline F. Ribeiro, Leon Wert-Lamas, Jon E. Henninger, Annamaria Gullà, Anil Aktas-Samur, Katia Todoerti, Srikanth Talluri, Woojun D. Park, Cinzia Federico, Francesca Scionti, Nicola Amodio, Giada Bianchi, Megan Johnstone, Na Liu, Doriana Gramegna, Domenico Maisano, Nicola A. Russo, Charles Lin, Yu-Tzu Tai, Antonino Neri, Dharminder Chauhan, Teru Hideshima, Masood A. Shammas, Pierfrancesco Tassone, Sergei Gryaznov, Richard A. Young, Kenneth C. Anderson, Carl D. Novina, Massimo Loda, Nikhil C. Munshi
Journal: Blood
Blood (2023) 141 (4): 391–405.
https://doi.org/10.1182/blood.2022016892
Published: 2023
Includes: Supplemental data
Journal Articles

CD73 Inhibition Reverses Immunosuppression and Has Potential As an Immunomodulatory Therapy in Patients with Multiple Myeloma

Melissa R Junttila, Arghya Ray, Robert Warne, Xi R Chen, Ting Du, Fang Lui, Subhash Katewa, Brian Blank, Jared Moore, Chudi Ndubaku, Christophe Colas, Pratik S Multani, Omar Nadeem, Dharminder Chauhan, Kenneth C. Anderson, Lori Friedman
Journal: Blood
Blood (2022) 140 (Supplement 1): 9957–9958.
https://doi.org/10.1182/blood-2022-168275
Published: 2022
Journal Articles

Targeting Autophagy to Overcome Resistance to Immunogenic Chemotherapy in High-Risk Multiple Myeloma

Annamaria Gulla, Eugenio Morelli, Mehmet K. Samur, Megan Johnstone, Cirino Botta, Delaney Vinaixa, Marcello Turi, Mariateresa Fulciniti, Kenneth Wen, Selma Cifric, Srikanth Talluri, Giada Bianchi, Rao Prabhala, Paul G. Richardson, Dharminder Chauhan, Ruben D. Carrasco, Teru Hideshima, Nikhil C Munshi, Kenneth C. Anderson
Journal: Blood
Blood (2022) 140 (Supplement 1): 7114–7115.
https://doi.org/10.1182/blood-2022-162653
Published: 2022
Journal Articles

26S Proteasome Non-Atpase Subunit 1, PSMD1/Rpn2, Is a Potential Therapeutic Target in Multiple Myeloma

Ting Du, Xueping Wan, Arghya Ray, Yao Yao, Ruben D. Carrasco, Mariateresa Fulciniti, Nikhil C Munshi, Dharminder Chauhan, Kenneth C. Anderson
Journal: Blood
Blood (2022) 140 (Supplement 1): 8853–8854.
https://doi.org/10.1182/blood-2022-163749
Published: 2022
Journal Articles

Analysis of COVID-19-Associated Proteins Identifies TANK-Binding Kinase 1 As an Immunotherapeutic Target in Multiple Myeloma

Arghya Ray, Ting DU, Krishan Chauhan, Dharminder Chauhan, Kenneth C. Anderson
Journal: Blood
Blood (2022) 140 (Supplement 1): 7176–7177.
https://doi.org/10.1182/blood-2022-170226
Published: 2022
Journal Articles

Bioprocessing of MIR17HG Results in Long and Short Noncoding RNAs with Targetable Tumor-Promoting Activity in Multiple Myeloma

Eugenio Morelli, Annamaria Gulla, Na Liu, Domenico Maisano, Anil Aktas-Samur, Nicola Amodio, Caroline Ribeiro, Leon Wert-Lamas, Jonathan Henninger, Srikanth Talluri, Megan Johnstone, Doriana Gramegna, Delaney Vinaixa, Antonino Neri, Dharminder Chauhan, Teru Hideshima, Masood A. Shammas, Pierfrancesco Tassone, Sergei Gryaznov, Richard A. Young, Kenneth C. Anderson, Carl D. Novina, Massimo Loda, Mariateresa Fulciniti, Mehmet K. Samur, Nikhil C Munshi
Journal: Blood
Blood (2022) 140 (Supplement 1): 1551–1552.
https://doi.org/10.1182/blood-2022-167604
Published: 2022
Journal Articles

Biology and Prognostic Implications of Bone Marrow Plasmacytoid Dendritic Cells in Multiple Myeloma Pathogenesis By Single-Cell RNA Sequencing

Arghya Ray, Leutz Buon, Ting DU, Xueping Wan, Dharminder Chauhan, Kenneth C. Anderson
Journal: Blood
Blood (2022) 140 (Supplement 1): 12436–12437.
https://doi.org/10.1182/blood-2022-170593
Published: 2022
Journal Articles

Gabarap Loss Mediates Immune Escape in High Risk Multiple Myeloma

Annamaria Gulla, Eugenio Morelli, Mehmet K. Samur, Cirino Botta, Megan Johnstone, Giada Bianchi, Mariateresa Fulciniti, Leona Yamamoto, Rao Prabhala, Kenneth Wen, Paul G. Richardson, Yu-Tzu Tai, Dharminder Chauhan, Teru Hideshima, Nikhil C. Munshi, Kenneth C. Anderson
Journal: Blood
Blood (2021) 138 (Supplement 1): 891.
https://doi.org/10.1182/blood-2021-148621
Published: 2021
Journal Articles

CD73 Inhibition Overcomes Immunosuppression and Triggers Autologous T-Cell Mediated Multiple Myeloma Cell Lysis in the Bone Marrow Milieu

Arghya Ray, Melissa R Junttila, Ting DU, Dena Sutimantanapi, Xi Chen, Bob Warne, Jae Chang, Brian Blank, Kejia Wu, Jared Moore, Chudi Ndubaku, Tatiana Zavorotinskaya, Omar Nadeem, Lori Friedman, Dharminder Chauhan, Kenneth C. Anderson
Journal: Blood
Blood (2021) 138 (Supplement 1): 2675.
https://doi.org/10.1182/blood-2021-148174
Published: 2021
Journal Articles

Combination of Melphalan Flufenamide and Anti-PD-L1 or Anti-CD38 Antibodies Enhances Anti-Myeloma Immunity

Arghya Ray, Ting DU, Nina N. Nupponen, Fredrik Lehmann, Jakob Lindberg, Joachim Gullbo, Paul G. Richardson, Dharminder Chauhan, Kenneth C. Anderson
Journal: Blood
Blood (2021) 138 (Supplement 1): 4357.
https://doi.org/10.1182/blood-2021-153705
Published: 2021
Journal Articles

Novel Cytokine-Mediated Mechanism of Action Identified By Quantitative Seroproteomics in Multiple Myeloma Patients Treated with Tagraxofusp, a Novel CD123-Directed Targeted Therapy

Arghya Ray, Clifton C. Mo, Ting DU, Arturo Olguin, Janice Chen, Christopher L Brooks, Tariq I. Mughal, Paul G. Richardson, Dharminder Chauhan, Kenneth C. Anderson
Journal: Blood
Blood (2021) 138 (Supplement 1): 1620.
https://doi.org/10.1182/blood-2021-153458
Published: 2021
Journal Articles

Ubiquitin Receptor PSMD4/Rpn10 Is a Novel Therapeutic Target in Myeloma

Ting DU, Yan Song, Arghya Ray, Ruben D. Carrasco, Sirano Dhe-Paganon, Dharminder Chauhan, Kenneth C. Anderson
Journal: Blood
Blood (2021) 138 (Supplement 1): 1591.
https://doi.org/10.1182/blood-2021-151377
Published: 2021
Journal Articles

Analysis of Sars-Cov-2-Associated Proteins Identify Tank-Binding Kinase-1 As an Immunotherapeutic Target in Multiple Myeloma

Arghya Ray, PhD, Ting DU, PhD, Krishan Chauhan, Yan Song, PhD, Dharminder Chauhan, PhD, Kenneth Anderson, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 29–30.
https://doi.org/10.1182/blood-2020-143393
Published: 2020
Journal Articles

RNA Regulator of Lipogenesis (RROL) Is a Novel Lncrna Mediating Protein-Protein Interaction at Gene Regulatory Loci Driving Lipogenic Programs in Multiple Myeloma

Eugenio Morelli, MD, Mariateresa Fulciniti, PhD, Mehmet K. Samur, PhD, Caroline Ribeiro, PhD, Leon Wert-Lamas, PhD, Annamaria Gulla, MD, Anil Aktas-Samur, PhD, Katia Todoerti, PhD, Srikanth Talluri, PhD, Woojun Daniel Park, Jonathan E Henninger, Cinzia Federico, PhD, Giada Bianchi, MD, Francesca Scionti, PhD, Yao Yao, Nicola Amodio, PhD, Charles Y Lin, PhD, Yu-Tzu Tai, PhD, Pierfrancesco Tassone, MD, Antonino Neri, MD, Dharminder Chauhan, PhD, Teru Hideshima, MD PhD, Richard A. Young, PhD, Kenneth Anderson, MD, Carl D. Novina, MD PhD, Massimo Loda, MD, Nikhil C. Munshi, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 20–21.
https://doi.org/10.1182/blood-2020-142514
Published: 2020
Journal Articles

A High Throughput Quantitative Seroproteomics Analysis of Multiple Myeloma Patients on Tagraxofusp Therapy Identifies Novel Cytokine-Assisted Mechanism of Action

Arghya Ray, PhD, Yan Song, PhD, Ting DU, PhD, Clifton C. Mo, MD, Arturo Olguin, Janice Chen, PhD, Christopher Brooks, PhD, Tariq I. Mughal, MD FRCP, Paul G. Richardson, MD, Dharminder Chauhan, PhD, Kenneth Anderson, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 34.
https://doi.org/10.1182/blood-2020-141571
Published: 2020
Journal Articles

Proteomic Characterization of Ubiquitin Receptor ADRM1/Rpn13

Yan Song, PhD, Ting DU, PhD, Arghya Ray, PhD, Krishan Chauhan, Mehmet K. Samur, PhD, Dharminder Chauhan, PhD, Kenneth Anderson, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 39.
https://doi.org/10.1182/blood-2020-139966
Published: 2020
Journal Articles

Bortezomib Induces Anti-Multiple Myeloma Immune Response Mediated By Cgas/Sting Pathway Activation, Type I Interferon Secretion, and Immunogenic Cell Death: Clinical Application

Annamaria Gulla, MD, Eugenio Morelli, MD, Mehmet Kemal Samur, PhD, Cirino Botta, MDPhD, Teru Hideshima, MD PhD, Giada Bianchi, MD, Mariateresa Fulciniti, PhD, Stefano Malvestiti, MD, Rao Prabhala, Srikanth Talluri, PhD, Yu-Tzu Tai, PhD, Kenneth Wen, Paul G. Richardson, MD, Ruben D. Carrasco, MD PhD, Dharminder Chauhan, PhD, Nikhil C. Munshi, MD, Kenneth Anderson, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 7–8.
https://doi.org/10.1182/blood-2020-140356
Published: 2020
Journal Articles

Blockade of Deubiquitylating Enzyme USP7 in Plasmacytoid Dendritic Cells Stimulates Anti-Myeloma Immunity

Arghya Ray, PhD, Ting DU, PhD, Yan Song, PhD, Sara J Buhrlage, PhD, Dharminder Chauhan, PhD, Kenneth Anderson, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 43.
https://doi.org/10.1182/blood-2020-138591
Published: 2020