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Tariq I. Mughal
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Journal Articles

Tagraxofusp, an Anti-CD123 Therapy, in Patients with Blastic Plasmacytoid Dendritic Cell Neoplasm and Prior or Concomitant Hematologic Malignancies: Subgroup Analysis of a Pivotal Trial

Naveen Pemmaraju, Marina Konopleva, Kendra Sweet, Anthony S. Stein, Sumithira Vasu, David A Rizzieri, Eunice S. Wang, Hagop Kantarjian, Christopher L. Brooks, Carole Paley, Tariq I. Mughal, Andrew A. Lane
Journal: Blood
Blood (2022) 140 (Supplement 1): 6155–6157.
https://doi.org/10.1182/blood-2022-159970
Published: 2022
Journal Articles

Phase I Study of Tagraxofusp with or without Chemotherapy in Pediatric Patients with Relapsed or Refractory CD123-Expressing Hematologic Malignancies: A Therapeutic Advances in Childhood Leukemia and Lymphoma (TACL) Consortium Trial

Adam J. Lamble, Yueh-Yun Chi, Bill H. Chang, Anupam Verma, Kelly E Faulk, Alexandra McLean Stevens, Lauren Pommert, Sarah Tucker, Benjamin Brookhart, Nirali N. Shah, Christopher L. Brooks, Tariq I. Mughal, Alan S. Wayne, Soheil Meshinchi, Todd M. Cooper
Journal: Blood
Blood (2022) 140 (Supplement 1): 6102–6103.
https://doi.org/10.1182/blood-2022-163503
Published: 2022
Journal Articles

Blastic Plasmacytoid Dendritic Cell Neoplasm Treated with Approved CD123-Targeted Therapy Tagraxofusp: The First European Real-World Evidence Prospective Registry of First-Line Adult Patients

Uwe Platzbecker, Emanuele Angelucci, Pau Montesinos, Roberto Massimo Lemoli, Alexandros Spyridonidis, Tariq I. Mughal, Carole Paley, Marcello Riggi, Mohamad Mohty
Journal: Blood
Blood (2022) 140 (Supplement 1): 11710–11712.
https://doi.org/10.1182/blood-2022-160127
Published: 2022
Journal Articles

Tagraxofusp, an Anti-CD123 Therapy, in Patients with Blastic Plasmacytoid Dendritic Cell Neoplasm: Subanalyses of a Pivotal Trial By Age and Baseline Disease Involvement

Naveen Pemmaraju, Marina Konopleva, Kendra Sweet, Anthony S. Stein, Sumithira Vasu, David A. Rizzieri, Eunice S. Wang, Hagop Kantarjian, Christopher L Brooks, Tariq I. Mughal, Andrew A. Lane
Journal: Blood
Blood (2021) 138 (Supplement 1): 874.
https://doi.org/10.1182/blood-2021-145109
Published: 2021
Journal Articles

The First Real-World Evidence Prospective Registry of Patients with Blastic Plasmacytoid Dendritic Cell Neoplasm Treated with Tagraxofusp, a CD123-Targeted Therapy, in Europe

Uwe Platzbecker, Emanuele Angelucci, Pau Montesinos, Roberto M. Lemoni, Alexandros Spyridonidis, Joaquín Casariego, Tariq I. Mughal, Mohamad Mohty
Journal: Blood
Blood (2021) 138 (Supplement 1): 5032.
https://doi.org/10.1182/blood-2021-145099
Published: 2021
Journal Articles

Tagraxofusp (SL-401) in Patients with Chronic Myelomonocytic Leukemia (CMML): Updated Results of an Ongoing Phase 1/2 Trial

Mrinal M. Patnaik, Haris Ali, Eunice S. Wang, Abdulraheem Yacoub, Vikas Gupta, Sangmin Lee, Gary J. Schiller, James M. Foran, Ayalew Tefferi, Christopher L Brooks, Guillermo Garcia-Manero, Tariq I. Mughal, Naveen Pemmaraju
Journal: Blood
Blood (2021) 138 (Supplement 1): 538.
https://doi.org/10.1182/blood-2021-147827
Published: 2021
Journal Articles

Integrated Safety Analysis of Tagraxofusp, a CD123-Directed Targeted Therapy, in Patients with Hematologic Malignancies

Naveen Pemmaraju, Hagop Kantarjian, Kendra Sweet, Eunice S. Wang, Andrew A. Lane, Haris Ali, Anthony S. Stein, Abdulraheem Yacoub, David A. Rizzieri, Sumithira Vasu, Vikas Gupta, Sangmin Lee, Gary J. Schiller, James M. Foran, Minakshi S. Taparia, Todd L. Rosenblat, Roland B. Walter, Debra Sieminski, Madhu Anant, Mrinal M. Patnaik, Tariq I. Mughal, Marina Konopleva
Journal: Blood
Blood (2021) 138 (Supplement 1): 2318.
https://doi.org/10.1182/blood-2021-145344
Published: 2021
Journal Articles

Novel Cytokine-Mediated Mechanism of Action Identified By Quantitative Seroproteomics in Multiple Myeloma Patients Treated with Tagraxofusp, a Novel CD123-Directed Targeted Therapy

Arghya Ray, Clifton C. Mo, Ting DU, Arturo Olguin, Janice Chen, Christopher L Brooks, Tariq I. Mughal, Paul G. Richardson, Dharminder Chauhan, Kenneth C. Anderson
Journal: Blood
Blood (2021) 138 (Supplement 1): 1620.
https://doi.org/10.1182/blood-2021-153458
Published: 2021
Journal Articles

Safety and Efficacy of Combining Tagraxofusp (SL-401) with Azacitidine or Azacitidine and Venetoclax in a Phase 1b Study for CD123 Positive AML, MDS, or BPDCN

Andrew A. Lane, Anthony S. Stein, Jacqueline S. Garcia, Jada L. Garzon, Ilene Galinsky, Marlise R. Luskin, Richard M. Stone, Eric S. Winer, Rebecca Leonard, Tariq I. Mughal, Christopher L Brooks, Marina Konopleva, Kristen E. Stevenson, Naveen Pemmaraju
Journal: Blood
Blood (2021) 138 (Supplement 1): 2346.
https://doi.org/10.1182/blood-2021-147486
Published: 2021
Journal Articles

A Phase 1/2 Study of Single Agent Tagraxofusp, a First-in-Class CD123-Targeted Therapy, in Patients with Myelofibrosis That Is Relapsed/Refractory Following JAK Inhibitor Therapy

Abdulraheem Yacoub, Mrinal M. Patnaik, Haris Ali, Eunice S. Wang, Vikas Gupta, Sangmin Lee, Gary J. Schiller, Minakshi S. Taparia, Animesh Pardanani, Ayalew Tefferi, Srdan Verstovsek, Joseph D. Khoury, Christopher L Brooks, Tariq I. Mughal, Naveen Pemmaraju
Journal: Blood
Blood (2021) 138 (Supplement 1): 140.
https://doi.org/10.1182/blood-2021-145276
Published: 2021
Journal Articles

A High Throughput Quantitative Seroproteomics Analysis of Multiple Myeloma Patients on Tagraxofusp Therapy Identifies Novel Cytokine-Assisted Mechanism of Action

Arghya Ray, PhD, Yan Song, PhD, Ting DU, PhD, Clifton C. Mo, MD, Arturo Olguin, Janice Chen, PhD, Christopher Brooks, PhD, Tariq I. Mughal, MD FRCP, Paul G. Richardson, MD, Dharminder Chauhan, PhD, Kenneth Anderson, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 34.
https://doi.org/10.1182/blood-2020-141571
Published: 2020
Journal Articles

A Multicenter Phase 1/2 Clinical Trial of Tagraxofusp, a CD123-Targeted Therapy, in Patients with Poor-Risk Primary and Secondary Myelofibrosis

Naveen Pemmaraju, MD, Vikas Gupta, MD FRCP, FRCPath, Haris Ali, MD, Abdulraheem Yacoub, MD, Eunice S. Wang, MD, Sangmin Lee, MD, Gary J. Schiller, MD, Christopher Brooks, PhD, Nicole Rupprecht, MS, Animesh Pardanani, MBBS, PhD, Ayalew Tefferi, MD, Moshe Talpaz, MD, Minakshi S. Taparia, MBBS, Tariq I. Mughal, MD FRCP, Srdan Verstovsek, MD PhD, Joseph D. Khoury, MD, Mrinal M. Patnaik, MDMBBS
Journal: Blood
Blood (2020) 136 (Supplement 1): 39–40.
https://doi.org/10.1182/blood-2020-137572
Published: 2020
Journal Articles

The Role of Comprehensive Mutational Profiling in Predicting Patients Who May Benefit from Autologous Hematopoietic Cell Transplant for Acute Myeloid Leukemia

Gabriel N. Mannis, MD, Nicole Therrien, Jessica Van Ziffle, Nicole Foley, Iwei Yeh, Shan Zhong, PhD, Jie He, PhD, Michelle Nahas, PhD, Charalambos Andreadis, MD MSCE, Lloyd E. Damon, MD, Rebecca L. Olin, MD MS, Sonam Prakash, MD, Tariq I Mughal, MD FRCP, Aaron C. Logan, MDPhDMPhil, Thomas G. Martin, III, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1423.
https://doi.org/10.1182/blood.V130.Suppl_1.1423.1423
Published: 2017
Journal Articles

Characterization of Ntrk fusions and Therapeutic Response to Ntrk Inhibition in Hematologic Malignancies

Justin Taylor, MD, Christina Marcelus, Dean Pavlick, Ryma Benayed, MD, Akihide Yoshimi, MD, Emiliano Cocco, PhD, Benjamin H Durham, MD BS, Jaclyn F Hechtman, MD, Young Rock Chung, MS, Kerry Mullaney, Justin M Watts, MD, Eli L Diamond, MD, Lee A Albacker, PhD, Tariq I Mughal, MD FRCP, Kevin Ebata, PhD, Brian B. Tuch, PhD, Nora Ku, MD, Maurizio Scaltriti, PhD, Maria E. Arcila, Siraj M Ali, MD PhD, David M. Hyman, MD, Omar Abdel-Wahab, MD, Jae H. Park, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 794.
https://doi.org/10.1182/blood.V130.Suppl_1.794.794
Published: 2017
Journal Articles

Next Generation Sequencing of Castleman Disease and Follicular Dendritic Cell Sarcomas Associated with Castleman Disease

Alexandra Nagy, MD, Aparna Bhaduri, Nahid Shahmarvand, MD, Jahanbanoo Shahryari, MD, James L. Zehnder, MD, Roger Warnke, MD, Tariq I Mughal, MD FRCP, Siraj M Ali, MD PhD, Robert S. Ohgami, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 4016.
https://doi.org/10.1182/blood.V130.Suppl_1.4016.4016
Published: 2017
Journal Articles

Comprehensive Genomic Profiling (CGP) Informs Molecular Diagnosis, Prognosis, and Therapeutic Decision-Making for Patients with Angioimmunoblastic T-Cell Lymphoma (AITL)

Samantha Morley, PhD, Jie He, PhD, Andrew M Intlekofer, MD PhD, Mark Bailey, MS, Michelle Nahas, PhD, Andreas Heilmann, PhD, Yakov Chudnovsky, PhD, David Fabrizio, PhD, Siraj M Ali, MD PhD, Doron Lipson, PhD, Philip J Stephens, PhD, Jeffrey S Ross, MD, Vincent A Miller, MD, Eric A Severson, MD PhD MMSc, Jo-Anne Vergilio, MD, Omar Abdel-Wahab, MD, Rachel Erlich, PhD, Tariq I Mughal, MD FRCP
Journal: Blood
Blood (2017) 130 (Supplement 1): 5134.
https://doi.org/10.1182/blood.V130.Suppl_1.5134.5134
Published: 2017
Journal Articles

Comprehensive Genomic Profiling (CGP) Identifies Novel BCL6 Rearrangements in Diverse Subtypes of Non-Hodgkin Lymphoma (NHL) As Well As Known Rearrangements Not Detected Using Standard of Care (SOC) Assays

Jo-Anne Vergilio, MD, Laurie M Gay, PhD, Lei Zhong, PhD, Mark Rosenzweig, PhD, Yakov Chudnovsky, PhD, Jie He, PhD, Michelle Nahas, PhD, Siraj M Ali, MD PhD, Sugganth Daniel, MD, Shakti Ramkissoon, MD PhD, James Suh, MD, Julia A Elvin, MD PhD, Tariq I Mughal, MD FRCP, Philip J Stephens, PhD, Vincent A Miller, MD, Rachel Erlich, PhD, Jeffrey S Ross, MD, Eric A Severson, MD PhD MMSc, Samantha Morley, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 417.
https://doi.org/10.1182/blood.V130.Suppl_1.417.417
Published: 2017
Journal Articles

High Risk Myeloma Is Characterized By the Bi-Allelic Inactivation of CDKN2C and RB1

Shweta S. Chavan, PhD, Christoph Heuck, MD, Jie He, PhD, Rusiana Tytarenko, Shayu Deshpande, PhD, Purvi Patel, Mark Bailey, MSc, Caleb K. Stein, MS, Owen W Stephens, Niels Weinhold, PhD, Nathan Petty, MS, Doug Steward, Leo Rasche, MD, Michael A Bauer, PhD, Cody Ashby, PhD, Erich Allen Peterson, PhD BS, MS, Shan Zhong, PhD, Michelle Nahas, PhD, Siraj M Ali, MD PhD, Jo-Anne Vergillo, MD, Jeff Ross, MD, Vincent A. Miller, MD, Phillip J Stephens, PhD, Carolina Schinke, MD, Maurizio Zangari, MD, Frits van Rhee, MD PhD, Bart Barlogie, MD PhD, Tariq I Mughal, MD, Faith E Davies, MD, Gareth J Morgan, MD PhD, Brian A Walker, PhD
Journal: Blood
Blood (2016) 128 (22): 4416.
https://doi.org/10.1182/blood.V128.22.4416.4416
Published: 2016
Journal Articles

Comprehensive Genomic Profiling for Improved Diagnosis and Therapy of Pediatric Acute Leukemias

Rachel Kobos, MD, Jie He, PhD, Peter G Steinherz, MD, Kevin J. Curran, MD, Thomas M. Renaud, MD, Christopher Forlenza, MD, Farid Boulad, MD, Susan Prockop, MD, Kristina Marie Knapp, Michael Walsh, MD, Mikhail Roshal, MD PhD, Lu Wang, MD PhD, Elli Papaemmanuil, PhD, Ahmet Dogan, Shan Zhong, PhD, Sohail Balasubramanian, M.S., Michelle Nahas, PhD, Jo-Anne Vergilio, MD, Jeff Ross, MD, Phil Stephens, PhD, Tariq I Mughal, MD, Vincent A. Miller, MD, Scott A. Armstrong, MD PhD, Ross L. Levine, MD, Alex Kentsis, MD PhD, Neerav N Shukla, MD
Journal: Blood
Blood (2016) 128 (22): 1605.
https://doi.org/10.1182/blood.V128.22.1605.1605
Published: 2016
Journal Articles

A Survey of Fusion Genes in Myeloma Identifies Kinase Domain Activation Which Could be Targeted with Available Treatments

Brian A Walker, PhD, Shweta S. Chavan, PhD, Jie He, PhD, Ruslana Tytarenko, Shan Zhong, PhD, Shayu Deshpande, PhD, Purvi Patel, Caleb K. Stein, MS, Owen W Stephens, Niels Weinhold, PhD, Nathan Petty, MS, Doug Steward, Carolina Schinke, MD, Leo Rasche, MD, Mark Bailey, MSc, Siraj Ali, Jo-Anne Vergillo, MD, Jeff Ross, MD, Vincent A. Miller, MD, Phillip J Stephens, PhD, Sharmilan Thanendrarajan, MD, Maurizio Zangari, MD, Frits van Rhee, MD PhD, Tariq I Mughal, MD, Faith E Davies, MD, Gareth J Morgan, MDPhD
Journal: Blood
Blood (2016) 128 (22): 117.
https://doi.org/10.1182/blood.V128.22.117.117
Published: 2016