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Andrew A. Lane
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Journal Articles

How I treat Blastic Plasmacytoid Dendritic Cell Neoplasm

Mohamed A Kharfan-Dabaja, Andrew A. Lane, Naveen Pemmaraju
Journal: Blood
Blood blood.2024024262.
https://doi.org/10.1182/blood.2024024262
Published: 2024
Journal Articles

Organ Involvement in BPDCN Is Associated with Sun Exposure History, TET2 and RAS Mutations, and Survival

Shai Shimony, Julia Keating, Christopher Fay, Marlise R. Luskin, Donna S. Neuberg, Nicole R. Leboeuf, Andrew A. Lane
Journal: Blood
Blood (2023) 142 (Supplement 1): 2865.
https://doi.org/10.1182/blood-2023-172975
Published: 2023
Journal Articles

Tagraxofusp in Combination with Azacitidine and Venetoclax in Newly Diagnosed CD123+ Acute Myeloid Leukemia, Expansion Cohort of a Phase 1b Multicenter Trial

Andrew A. Lane, Jacqueline S. Garcia, Evangeline G. Raulston, Jada L. Garzon, Ilene Galinsky, Emilie W. Baxter, Rebecca Leonard, Daniel J. DeAngelo, Marlise R. Luskin, Christopher R. Reilly, Maximilian Stahl, Richard M Stone, Rahul Vedula, Martha Wadleigh, Eric S. Winer, Tariq Mughal, Christopher Brooks, Ira V. Gupta, Kristen E. Stevenson, Donna S. Neuberg, Siyang Ren, Marina Y. Konopleva, Anthony Stein, Naveen Pemmaraju
Journal: Blood
Blood (2023) 142 (Supplement 1): 4277.
https://doi.org/10.1182/blood-2023-180010
Published: 2023
Journal Articles

A Simple Prediction Model of Outcomes after Allogeneic Hematopoietic Stem Cell Transplant (HCT) in Myelodysplastic Syndromes Using HCT-Comorbidity Index, Cytogenetic Risk, and Platelet Count

Stacey M Frumm, Haesook T. Kim, Amar H Kelkar, Vincent T. Ho, Mahasweta Gooptu, Christopher James Gibson, John Koreth, Roman M. Shapiro, Rizwan Romee, Sarah Nikiforow, Joseph H. Antin, Robert J. Soiffer, Benjamin Rolles, Shai Shimony, Jan Philipp Bewersdorf, Tariq Kewan, Abdulrahman Alhajahjeh, Marlise R. Luskin, Jacqueline S. Garcia, Evan C. Chen, Andrew A. Lane, Martha Wadleigh, Eric S. Winer, Richard M Stone, Daniel J. DeAngelo, Amer M. Zeidan, Coleman Lindsley, Corey Cutler, Maximilian Stahl
Journal: Blood
Blood (2023) 142 (Supplement 1): 2246.
https://doi.org/10.1182/blood-2023-185315
Published: 2023
Journal Articles

Defining a Targetable Leukemia Intrinsic Dependency on Noncanonical PI3Kgamma Signaling

Qingyu Luo, Evangeline G. Raulston, Miguel A. Prado, Xiaowei Wu, Kira Gritsman, Kezhi Yan, Christopher A. G. Booth, Ran Xu, Peter van Galen, John G. Doench, Shai Shimony, Henry W. Long, Donna S. Neuberg, Joao A. Paulo, Andrew A. Lane
Journal: Blood
Blood (2023) 142 (Supplement 1): 578.
https://doi.org/10.1182/blood-2023-178895
Published: 2023
Journal Articles

Post-Transplant T Cell Clonotype Diversity Is Associated with Survival in Patients with TP53-Mutated Acute Myeloid Leukemia

Nurefsan Sariipek, Kseniia R. Safina, Corey Cutler, Vincent T. Ho, John Koreth, Coleman Lindsley, Marlise R. Luskin, Jacqueline S. Garcia, Doreen Hearsey, Wesley S Lu, Shuqiang Li, Kenneth J. Livak, Gabriel K. Griffin, Robert J. Soiffer, Jerome Ritz, Catherine J Wu, Joseph H. Antin, Andrew A. Lane, Peter Van Galen, Mahasweta Gooptu
Journal: Blood
Blood (2023) 142 (Supplement 1): 2176.
https://doi.org/10.1182/blood-2023-181863
Published: 2023
Journal Articles

Post Allogeneic Stem Cell Transplant Outcomes Following Response to Hypomethylating Agent Therapy in Myelodysplastic Syndromes Are Predicted By Persistent International Prognostic Scoring System-Molecular Risk

Stacey M Frumm, Haesook T. Kim, Amar H Kelkar, Vincent T. Ho, Mahasweta Gooptu, Christopher James Gibson, John Koreth, Roman M. Shapiro, Rizwan Romee, Sarah Nikiforow, Joseph H. Antin, Robert J. Soiffer, Benjamin Rolles, Shai Shimony, Jan Philipp Bewersdorf, Tariq Kewan, Abdulrahman Alhajahjeh, Marlise R. Luskin, Jacqueline S. Garcia, Evan C. Chen, Andrew A. Lane, Martha Wadleigh, Eric S. Winer, Richard M Stone, Daniel J. DeAngelo, Amer M. Zeidan, Coleman Lindsley, Corey Cutler, Maximilian Stahl
Journal: Blood
Blood (2023) 142 (Supplement 1): 3618.
https://doi.org/10.1182/blood-2023-185220
Published: 2023
Journal Articles

DDX41 : here, there…and everywhere

Christopher R. Reilly, Andrew A. Lane
Journal: Blood
Blood (2023) 142 (14): 1177–1178.
https://doi.org/10.1182/blood.2023021850
Published: 2023
Journal Articles

North American Blastic Plasmacytoid Dendritic Cell Neoplasm Consortium: position on standards of care and areas of need

Naveen Pemmaraju, Hagop Kantarjian, Kendra Sweet, Eunice Wang, Jayastu Senapati, Nathaniel R. Wilson, Marina Konopleva, Arthur E. Frankel, Vikas Gupta, Ruben Mesa, Matthew Ulrickson, Edward Gorak, Sumeet Bhatia, Tulin Budak-Alpdogan, James Mason, Maria Teresa Garcia-Romero, Norma Lopez-Santiago, Gabriela Cesarman-Maus, Pankit Vachhani, Sangmin Lee, Vijaya Raj Bhatt, William Blum, Roland B. Walter, Dale Bixby, Ivana Gojo, Madeleine Duvic, Raajit K. Rampal, Marcos de Lima, James Foran, Amir T. Fathi, Aric Cameron Hall, Meagan A. Jacoby, Jeffrey Lancet, Gabriel Mannis, Anthony S. Stein, Alice Mims, David Rizzieri, Rebecca Olin, Alexander Perl, Gary Schiller, Paul Shami, Richard M. Stone, Stephen Strickland, Matthew J. Wieduwilt, Naval Daver, Farhad Ravandi, Sumithira Vasu, Monica Guzman, Gail J. Roboz, Joseph Khoury, Muzaffar Qazilbash, Phyu P. Aung, Branko Cuglievan, Yazan Madanat, Mohamed A. Kharfan-Dabaja, Anna Pawlowska, Justin Taylor, Martin Tallman, Prajwal Dhakal, Andrew A. Lane
Journal: Blood
Blood (2023) 141 (6): 567–578.
https://doi.org/10.1182/blood.2022017865
Published: 2023
Journal Articles

Clonal Hematopoiesis Evolves into Dendritic Cell Neoplasm through the Acquisition of UV Mutations in the Skin

Peter Van Galen, Gabriel K. Griffin, Christopher A.G. Booth, Katsuhiro Togami, Sun Sook Chung, Daniel Ssozi, Julia A. Verga, Juliette M.C. Bouyssou, Yoke Seng Lee, Vignesh Shanmugam, Nicole R. LeBoeuf, Elizabeth A. Morgan, Bradley E. Bernstein, Volker Hovestadt, Andrew A. Lane
Journal: Blood
Blood (2022) 140 (Supplement 1): 1998–1999.
https://doi.org/10.1182/blood-2022-163666
Published: 2022
Journal Articles

BPDCN MYB Fusions Bind Cell Cycle Gene Promoters, Reactivate Self-Renewal in Progenitor Cells and Induce Myeloid/Dendritic Leukemia

Christopher A.G. Booth, Juliette M.C. Bouyssou, Katsuhiro Togami, Andrew A. Lane
Journal: Blood
Blood (2022) 140 (Supplement 1): 2000–2001.
https://doi.org/10.1182/blood-2022-159150
Published: 2022
Journal Articles

Tagraxofusp, an Anti-CD123 Therapy, in Patients with Blastic Plasmacytoid Dendritic Cell Neoplasm and Prior or Concomitant Hematologic Malignancies: Subgroup Analysis of a Pivotal Trial

Naveen Pemmaraju, Marina Konopleva, Kendra Sweet, Anthony S. Stein, Sumithira Vasu, David A Rizzieri, Eunice S. Wang, Hagop Kantarjian, Christopher L. Brooks, Carole Paley, Tariq I. Mughal, Andrew A. Lane
Journal: Blood
Blood (2022) 140 (Supplement 1): 6155–6157.
https://doi.org/10.1182/blood-2022-159970
Published: 2022
Journal Articles

Safety and Efficacy of Combining Tagraxofusp (SL-401) with Azacitidine or Azacitidine and Venetoclax in a Phase 1b Study for CD123 Positive AML, MDS, or BPDCN

Andrew A. Lane, Anthony S. Stein, Jacqueline S. Garcia, Jada L. Garzon, Ilene Galinsky, Marlise R. Luskin, Richard M. Stone, Eric S. Winer, Rebecca Leonard, Tariq I. Mughal, Christopher L Brooks, Marina Konopleva, Kristen E. Stevenson, Naveen Pemmaraju
Journal: Blood
Blood (2021) 138 (Supplement 1): 2346.
https://doi.org/10.1182/blood-2021-147486
Published: 2021
Journal Articles

Tagraxofusp, an Anti-CD123 Therapy, in Patients with Blastic Plasmacytoid Dendritic Cell Neoplasm: Subanalyses of a Pivotal Trial By Age and Baseline Disease Involvement

Naveen Pemmaraju, Marina Konopleva, Kendra Sweet, Anthony S. Stein, Sumithira Vasu, David A. Rizzieri, Eunice S. Wang, Hagop Kantarjian, Christopher L Brooks, Tariq I. Mughal, Andrew A. Lane
Journal: Blood
Blood (2021) 138 (Supplement 1): 874.
https://doi.org/10.1182/blood-2021-145109
Published: 2021
Journal Articles

Integrated Safety Analysis of Tagraxofusp, a CD123-Directed Targeted Therapy, in Patients with Hematologic Malignancies

Naveen Pemmaraju, Hagop Kantarjian, Kendra Sweet, Eunice S. Wang, Andrew A. Lane, Haris Ali, Anthony S. Stein, Abdulraheem Yacoub, David A. Rizzieri, Sumithira Vasu, Vikas Gupta, Sangmin Lee, Gary J. Schiller, James M. Foran, Minakshi S. Taparia, Todd L. Rosenblat, Roland B. Walter, Debra Sieminski, Madhu Anant, Mrinal M. Patnaik, Tariq I. Mughal, Marina Konopleva
Journal: Blood
Blood (2021) 138 (Supplement 1): 2318.
https://doi.org/10.1182/blood-2021-145344
Published: 2021
Journal Articles

Experience with IMGN632, a Novel CD123-Targeting Antibody-Drug Conjugate (ADC), in Frontline Patients with Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN)

Naveen Pemmaraju, Giovanni Martinelli, Elisabetta Todisco, Andrew A. Lane, Evelyn Acuña-Cruz, Eric Deconinck, Eunice S. Wang, Kendra Sweet, David A Rizzieri, Giovanni Marconi, Luca Mazzarella, Daniel J. DeAngelo, Pau Montesinos, Federica Gigli, Harry P. Erba, Marina Konopleva, Hagop Kantarjian, Roland B. Walter, Ahmed Aribi, Delphine Lebon, Moshe Y. Levy, Callum M Sloss, Kara E Malcolm, Patrick A Zweidler-McKay, Naval Daver
Journal: Blood
Blood (2021) 138 (Supplement 1): 1284.
https://doi.org/10.1182/blood-2021-146666
Published: 2021
Journal Articles

Antifungal Prophylaxis: Impact on Outcomes of Newly Diagnosed AML Patients Treated with a Hypomethylating Agent and Venetoclax

Evan C. Chen, Yiwen Liu, Eric S. Winer, Marlise R. Luskin, Martha Wadleigh, Andrew A. Lane, Rahul S. Vedula, Coleman Lindsley, Kevin Copson, Anne Charles, Donna S. Neuberg, Nicolas C. Issa, Daniel J. DeAngelo, Richard M. Stone, Jacqueline S. Garcia
Journal: Blood
Blood (2021) 138 (Supplement 1): 4126.
https://doi.org/10.1182/blood-2021-148717
Published: 2021
Journal Articles

A Study of IMGN632, a Novel CD123-Targeting Antibody-Drug Conjugate, for Patients with Frontline and Relapsed/Refractory Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN)

Naveen Pemmaraju, Giovanni Marconi, Elisabetta Todisco, Pau Montesinos, Andrew A. Lane, Kendra Sweet, Eunice S. Wang, Eric Deconinck, David A Rizzieri, Roland B. Walter, Ahmed Aribi, Delphine Lebon, Moshe Y. Levy, Luca Mazzarella, Giovanni Martinelli, Federica Gigli, Harry P. Erba, Evelyn Acuña-Cruz, Marina Konopleva, Hagop Kantarjian, Callum M Sloss, Jiuzhou Wang, Kara E Malcolm, Patrick A Zweidler-McKay, Daniel J. DeAngelo, Naval Daver
Journal: Blood
Blood (2021) 138 (Supplement 1): 4429.
https://doi.org/10.1182/blood-2021-146681
Published: 2021
Journal Articles

Single-cell RNA-seq reveals developmental plasticity with coexisting oncogenic states and immune evasion programs in ETP-ALL

Praveen Anand, Amy Guillaumet-Adkins, Valeriya Dimitrova, Huiyoung Yun, Yotam Drier, Noori Sotudeh, Anna Rogers, Madhu M. Ouseph, Monica Nair, Sayalee Potdar, Randi Isenhart, Jake A. Kloeber, Tushara Vijaykumar, Leili Niu, Tiffaney Vincent, Guangwu Guo, Julia Frede, Marian H. Harris, Andrew E. Place, Lewis B. Silverman, David T. Teachey, Andrew A. Lane, Daniel J. DeAngelo, Jon C. Aster, Bradley E. Bernstein, Jens G. Lohr, Birgit Knoechel
Journal: Blood
Blood (2021) 137 (18): 2463–2480.
https://doi.org/10.1182/blood.2019004547
Published: 2021
Includes: Supplemental data
Journal Articles

Clinical Profile of IMGN632, a Novel CD123-Targeting Antibody-Drug Conjugate (ADC), in Patients with Relapsed/Refractory (R/R) Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN)

Naveen Pemmaraju, MD, Giovanni Martinelli, MD, Elisabetta Todisco, MDPhD, Andrew A Lane, MD PhD, Evelyn Acuña-Cruz, MD, Eric Deconinck, MDPhD, Eunice S. Wang, MD, Kendra L. Sweet, MD MS, David A Rizzieri, MD, Luca Mazzarella, MDPhD, Daniel J. DeAngelo, MD PhD, Pau Montesinos, MD PhD, Corrado Tarella, Harry P. Erba, MD PhD, Marina Konopleva, MD PhD, Hagop M. Kantarjian, MD, Callum M Sloss, PhD, Kara E Malcolm, RN, Patrick A Zweidler-McKay, MDPhD, Naval Daver, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 11–13.
https://doi.org/10.1182/blood-2020-139903
Published: 2020