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Journal Articles

Bi-specific T-cell engagers as a bridge to ciltacabtagene autoleucel in Relapsed/Refractory multiple myeloma: Real-world outcomes in an underserved urban population

Free
Santiago Beltran, Emma Cordover, Xiaoyi Zhang, Kimberly Seymour, Buse Eglenen Polat, Ankit Tanwar, Sidney Hwang, Nicholas Li, Ella Wesson, Aditi Shastri, Noah Kornblum, Lauren Shapiro, Mendel Goldfinger, Ioannis Mantzaris, Dennis Cooper, Kira Gritsman, Marina Konopleva, Amit Verma, Ridhi Gupta, R. Alejandro Sica
Journal: Blood
Blood (2025) 146 (Supplement 1): 4577.
https://doi.org/10.1182/blood-2025-4577
Published: 2025
Journal Articles

Development of a machine learning model to predict overall survival in patients with peripheral T-cell lymphoma in a minority enriched population

Free
Kimberly Seymour, Nicholas Li, Emma Cordover, Sidney Hwang, Ella Wesson, Xiaoyi Zhang, Buse Eglenen Polat, Ankit Tanwar, Lauren Shapiro, Noah Kornblum, Aditi Shastri, David Levitz, Mendel Goldfinger, Kira Gritsman, Ioannis Mantzaris, Ridhi Gupta, Marina Konopleva, Dennis Cooper, Eric Feldman, Amit Verma, R. Alejandro Sica
Journal: Blood
Blood (2025) 146 (Supplement 1): 2568.
https://doi.org/10.1182/blood-2025-2568
Published: 2025
Journal Articles

Low dose weekly HMA-venetoclax dosing is associated with greater cost-effective efficacy than standard dosing in AML/MDS: Real-world evidence

Free
Wing Fai Li, Bradley Rockwell, Xinhe Shan, Ioannis Mantzaris, Aditi Shastri, Kira Gritsman, R. Alejandro Sica, Noah Kornblum, David Levitz, Lauren Shapiro, Ridhi Gupta, Stephen Peeke, Anne Munoz, Aradhika Dhawan, Karen Fehn, Monica Comas, Jhannine Verceles, Dennis Cooper, Marina Konopleva, Eric Feldman, Amit Verma, Mendel Goldfinger
Journal: Blood
Blood (2025) 146 (Supplement 1): 4429.
https://doi.org/10.1182/blood-2025-4429
Published: 2025
Journal Articles

TTLL4 glutamyltransferase is a therapeutic target for NPM1-mutated Acute Myeloid Leukemia

Free
Alexandra Schurer, Humaira Ilyas, Maxim Maron, Subray Hegde, Melissa Leyden, Irene Roy, Rotila Hyka, Lucas Dada, Jeffrey Shabanowitz, Donald Hunt, Ellen Angeles, Victor Morell, Benjamin Lorton, Shira Glushakow-Smith, Daniel Borger, Yuxuan Wang, Linde Miles, Roger Belizaire, Seiya Kitamura, Kira Gritsman, David Shechter
Journal: Blood
Blood (2025) 146 (Supplement 1): 869.
https://doi.org/10.1182/blood-2025-869
Published: 2025
Journal Articles

Assessing diagnostic accuracy of DermPathGPT01 for dermatologic diagnosis in post-allogeneic stem cell transplant patients

Free
Ella Wesson, Kimberly Seymour, Emma Cordover, Sidney Hwang, Xiaoyi Zhang, Buse Eglenen Polat, Aditi Shastri, Eric Feldman, Noah Kornblum, Ankit Tanwar, Lauren Shapiro, Mendel Goldfinger, Ioannis Mantzaris, Dennis Cooper, Ridhi Gupta, Kira Gritsman, Marina Konopleva, Amit Verma, Benedict Wu, Beth McLellan, R. Alejandro Sica
Journal: Blood
Blood (2025) 146 (Supplement 1): 7875.
https://doi.org/10.1182/blood-2025-7875
Published: 2025
Journal Articles

BCL-2 inhibition in North American adult T-cell leukemia/lymphoma: Preclinical insights and early clinical outcomes

Free
Ankit Tanwar, Emma Cordover, Salman Sadullah Usmani, Zixuan Tong, Kith Pradhan, Ella Wesson, Latoya S Townsend, Ioannis Mantzaris, Mendel Goldfinger, Nishi Shah, Aditi Shastri, Noah Kornblum, Dennis Cooper, Ridhi Gupta, Nechama Dreyfus, Julie Nguyen, Lauren Shapiro, Eric Feldman, Beth McLellan, Alyssa de Castro, Buse Eglenen Polat, Xingxing Zang, Ali Bazarbachi, Murali Janakiram, Gregoire Lauvau, Kira Gritsman, B. Hilda Ye, Amit Verma, Marina Konopleva, R. Alejandro Sica
Journal: Blood
Blood (2025) 146 (Supplement 1): 3304.
https://doi.org/10.1182/blood-2025-3304
Published: 2025
Journal Articles

First-in-human study of CTX130, a CD70-directed allogeneic CAR T therapy, in adult T-cell leukemia/lymphoma: Clinical and genomics findings from a long-term follow-up of subgroup analysis from the cobalt-LYM Phase 1 trial

Free
Emma Cordover, Kimberly Seymour, Buse Eglenen Polat, Santiago Beltran, Xiaoyi Zhang, Ankit Tanwar, Sidney Hwang, Nicholas Li, Ella Wesson, Ziliang Li, Joy Mendonez, Alissa Keegan, Aditi Shastri, Noah Kornblum, Lauren Shapiro, Mendel Goldfinger, Ioannis Mantzaris, Dennis Cooper, Kira Gritsman, Marina Konopleva, Ridhi Gupta, Amit Verma, Swami Iyer, Ali Bazarbachi, R. Alejandro Sica
Journal: Blood
Blood (2025) 146 (Supplement 1): 4143.
https://doi.org/10.1182/blood-2025-4143
Published: 2025
Journal Articles

Efficacy of a novel BCL-xL degrader, DT2216, in preclinical models of JAK2 -mutated post-MPN AML

Open Access
Zhe Wang, Anna Skwarska, Gowri Poigaialwar, Sovira Chaudhry, Alba Rodriguez-Meira, Pinpin Sui, Emmanuel Olivier, Yannan Jia, Varun Gupta, Warren Fiskus, Cassandra L. Ramage, Guangrong Zheng, Alexandra Schurer, Kira Gritsman, Eirini P. Papapetrou, Kapil Bhalla, Daohong Zhou, Adam J. Mead, Raajit K. Rampal, Jeffrey W. Tyner, Hussein A. Abbas, Naveen Pemmaraju, Qi Zhang Tatarata, Marina Konopleva
Journal: Blood
Blood (2025) 146 (3): 341–355.
https://doi.org/10.1182/blood.2024027117
Published: 2025
Includes: Supplemental data
Journal Articles

Venetoclax plus daunorubicin and cytarabine for newly diagnosed acute myeloid leukemia: results of a phase 1b study

Open Access
Clinical Trials & Observations Brief Report
Ioannis Mantzaris, Mendel Goldfinger, Matan Uriel, Aditi Shastri, Nishi Shah, Kira Gritsman, Noah S. Kornblum, Lauren Shapiro, Roberto Alejandro Sica, Anne Munoz, Nicole Chambers, Aradhika Dhawan, Jhannine Alyssa Verceles, Karen Fehn, Balda Tirone, Lamisha Shah, Shaunmonique Clark, Chenxin Zhang, Mimi Kim, Dennis L. Cooper, Amit Verma, Marina Konopleva, Eric J. Feldman
Journal: Blood
Blood (2025) 145 (17): 1870–1875.
https://doi.org/10.1182/blood.2024026700
Published: 2025
Includes: Supplemental data
Journal Articles

A weekly low-dose regimen of decitabine and venetoclax is efficacious and less myelotoxic in a racially diverse cohort

Free
Clinical Trials & Observations
Mendel Goldfinger, Ioannis Mantzaris, Aditi Shastri, Yogen Saunthararajah, Kira Gritsman, R. Alejandro Sica, Noah Kornblum, Nishi Shah, David Levitz, Bradley Rockwell, Lauren C. Shapiro, Ridhi Gupta, Kith Pradhan, Xiaonan Xue, Anne Munoz, Aradhika Dhawan, Karen Fehn, Monica Comas, Jhannine Alyssa Verceles, Brian A. Jonas, Suman Kambhampati, Yang Shi, Ira Braunschweig, Dennis L. Cooper, Marina Konopleva, Eric J. Feldman, Amit Verma
Journal: Blood
Blood (2024) 144 (22): 2360–2363.
https://doi.org/10.1182/blood.2024025834
Published: 2024
Includes: Supplemental data
Journal Articles

Post-Transplantation Cyclophosphamide and Abatacept Graft-Versus-Host-Disease Prophylaxis Shows Improved Outcomes in North American Adult T-Cell Leukemia/Lymphoma

Free
Julie Nguyen, Abdul-Hamid Bazarbachi, Kith Pradhan, John Yan, Emma Cordover, Daniel K Reef, Riya Patel, Rama Al Hamed, Astha Thakkar, Shafia Rahman, Diego Adrianzen Herrera, Ryann Quinn, Alyssa de Castro, Kailyn Gillick, Jennat Mustafa, Fariha Khatun, Amanda Lombardo, Latoya S Townsend, Michelly Abreu, Nicole Chambers, Richard Elkind, Yang Shi, Yanhua Wang, Olga Derman, Kira Gritsman, Ulrich Steidl, Mendel Goldfinger, Noah Kornblum, Aditi Shastri, Ioannis Mantzaris, Lizamarie Bachier Rodriguez, Brittany Moavero, Jhannine Verceles, Angela Czavar, Lauren Shapiro, Trent Wang, Juan Carlos Ramos, Nishi Shah, Ridhi Gupta, Marina Konopleva, Ira Braunschweig, Amit Verma, B. Hilda Ye, Murali Janakiram, Dennis L Cooper, R. Alejandro Sica
Journal: Blood
Blood (2024) 144 (Supplement 1): 7367.
https://doi.org/10.1182/blood-2024-207521
Published: 2024
Journal Articles

Mogamulizumab Shows Significant Activity with Tolerable Toxicity in a Real-World North American Adult T-Cell Leukemia/Lymphoma (ATLL) Cohort

Free
Emma Cordover, Kith Pradhan, Latoya S. Townsend, Mendel Goldfinger, Ioannis Mantzaris, Nishi Shah, Aditi Shastri, Noah Kornblum, Dennis L Cooper, Ridhi Gupta, Lauren Shapiro, Kira Gritsman, Marina Konopleva, Alyssa de Castro, Roy Browne, Salvatore Lia, Amit Verma, Ali Bazarbachi, B. Hilda Ye, Murali Janakiram, R. Alejandro Sica
Journal: Blood
Blood (2024) 144 (Supplement 1): 6418.
https://doi.org/10.1182/blood-2024-210619
Published: 2024
Journal Articles

Metronomic Low-Dose Regimen of Decitabine and Venetoclax Is Safe and Efficacious for Chronic Myelomonocytic Leukemia

Free
Bradley Rockwell, Ioannis Mantzaris, Aditi Shastri, Kira Gritsman, R. Alejandro Sica, Noah Kornblum, Nishi Shah, David Levitz, Lauren Shapiro, Ridhi Gupta, Annemarie Munoz, Aradhika Dhawan, Karen Fehn, Monica Comas, Jhannine Verceles, Dennis L Cooper, Marina Konopleva, Eric J. Feldman, Amit Verma, Mendel Goldfinger
Journal: Blood
Blood (2024) 144 (Supplement 1): 6723.
https://doi.org/10.1182/blood-2024-211307
Published: 2024
Journal Articles

Promising Safety and Efficacy Data for Peginterferon Alfa-2a (PEG-IFN) and Bictegravir/Emtricitabine/Tenofovir Alafenamide (Biktarvy) in a North American Adult T-Cell Leukemia Lymphoma (NA-ATLL) Cohort of Patients

Free
Nechama Dreyfus, Emma Cordover, Kith Pradhan, Latoya S Townsend, Mendel Goldfinger, Ioannis Mantzaris, Nishi Shah, Aditi Shastri, Noah Kornblum, Dennis L Cooper, Ridhi Gupta, Lauren Shapiro, Kira Gritsman, Marina Konopleva, Beth McLellan, Simon Zhen, Alyssa de Castro, Salvatore Lia, Virleny Garcia, Roy Browne, Eric Meyerowitz, Yoram Puius, Margaret McCort, Yang Shi, Yanhua Wang, Amit Verma, B. Hilda Ye, Murali Janakiram, Abdul-Hamid Bazarbachi, R. Alejandro Sica
Journal: Blood
Blood (2024) 144 (Supplement 1): 3067.
https://doi.org/10.1182/blood-2024-208199
Published: 2024
Journal Articles

Assessing the Utility of Interim Bone Marrow Results in Acute Myeloid Leukemia Induction

Free
Mumtu Lalla, Matan Uriel, Mendel Goldfinger, Aditi Shastri, Kira Gritsman, Nishi Shah, Noah Kornblum, Lauren Shapiro, R. Alejandro Sica, Annemarie Munoz, Nicole Chambers, Aradhika Dhawan, Karen Fehn, Balda Tirone, Lamisha Shah, Shaunmonique Clark, Amit Verma, Mimi Kim, Dennis L Cooper, Eric J. Feldman, Marina Konopleva, Ioannis Mantzaris
Journal: Blood
Blood (2024) 144 (Supplement 1): 6175.
https://doi.org/10.1182/blood-2024-208911
Published: 2024
Journal Articles

Current Trends of Severe Renal Impairment in Newly Diagnosed Multiple Myeloma: A Single-Center Experience in a Low Socio-Economic Population

Free
M Bakri Hammami, Jeevan Shivakumar, Nina Samuel, Rajvi Gor, Mendel Goldfinger, Noah Kornblum, Lauren Shapiro, Aditi Shastri, Ridhi Gupta, David Levitz, Marina Konopleva, Eric J. Feldman, Kira Gritsman, R. Alejandro Sica, Ioannis Mantzaris, Amit Verma, Dennis L Cooper, Nishi Shah
Journal: Blood
Blood (2024) 144 (Supplement 1): 6999.
https://doi.org/10.1182/blood-2024-208770
Published: 2024
Journal Articles

Venetoclax Combined with “7+3” Induction Chemotherapy Induces High MRD-Negative Response Rates in Newly Diagnosed AML Patients Fit for Intensive Chemotherapy across Ages

Free
Ioannis Mantzaris, Matan Uriel, Mendel Goldfinger, Aditi Shastri, Nishi Shah, Kira Gritsman, Noah Kornblum, Lauren Shapiro, R. Alejandro Sica, Annemarie Munoz, Nicole Chambers, Aradhika Dhawan, Karen Fehn, Balda Tirone, Lamisha Shah, Shaunmonique Clark, Mimi Kim, Chenxin Zhang, Dennis L Cooper, Amit Verma, Marina Konopleva, Eric J. Feldman
Journal: Blood
Blood (2024) 144 (Supplement 1): 57.
https://doi.org/10.1182/blood-2024-211685
Published: 2024
Journal Articles

Assessing the Performance of the Iceland Screens, Treats, or Prevents Multiple Myeloma (iStopMM) Model in a Multicultural Bronx Cohort: Implications for Monoclonal Gammopathy of Undetermined Significance (MGUS) Risk Stratification

Free
Rajvi Gor, Jeevan Shivakumar, Pallavi Surana, John X Wei, Irina Murakhovskaya, Mendel Goldfinger, Noah Kornblum, Lauren Shapiro, Aditi Shastri, Ridhi Gupta, David Levitz, Marina Konopleva, Eric J. Feldman, Kira Gritsman, R. Alejandro Sica, Ioannis Mantzaris, Amit Verma, Dennis L Cooper, Murali Janakiram, Nishi Shah
Journal: Blood
Blood (2024) 144 (Supplement 1): 3307.
https://doi.org/10.1182/blood-2024-201590
Published: 2024
Journal Articles

Neurotoxicity of Axicabtagene Ciloleucel in an Ethnically Diverse, Real-World Cohort

Free
Elizabeth Zeldin, Samantha J Cheng, Ryann Quinn, Kith Pradhan, Mendel Goldfinger, Ioannis Mantzaris, Nishi Shah, Aditi Shastri, Noah Kornblum, Dennis L Cooper, Ridhi Gupta, Lauren Shapiro, Kira Gritsman, Ahmed Abbasi, Amit Verma, Ira Braunschweig, Katharine McNeill, Mark Milstein, R. Alejandro Sica
Journal: Blood
Blood (2024) 144 (Supplement 1): 7201.
https://doi.org/10.1182/blood-2024-201715
Published: 2024
Journal Articles

A Phase 1 Study Investigating the Safety and Efficacy of Danvatirsen As Monotherapy Followed By Combination with Venetoclax in Patients with Relapsed/Refractory MDS and AML

Free
Aditi Shastri, Mendel Goldfinger, Ioannis Mantzaris, Guillermo Garcia-Manero, Tapan M. Kadia, Jing Ning, Balda Tirone, Rikin Gandhi, Farhad Ravandi, Naveen Pemmaraju, Guillermo Montalban-Bravo, Annemarie Munoz, Michelle Golez, Lianchun Xiao, Kith Pradhan, Karen Fehn, Lamisha Shah, Hui Zhang, Samarpana Chakraborty, Eric J. Feldman, Nicholas J. Short, Jayastu Senapati, Dennis L Cooper, Alejandro Sica, Noah Kornblum, Lauren Shapiro, Nishi Shah, Susan MacIntyre, Ulrich Steidl, Amit Verma, Kira Gritsman, Andrew Denker, Marina Konopleva, Naval Daver
Journal: Blood
Blood (2024) 144 (Supplement 1): 4265.5.
https://doi.org/10.1182/blood-2024-208998
Published: 2024