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B. Hilda Ye
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Journal Articles

North American Adult T-Cell Leukemia/Lymphoma Has Frequent Mutations in CCR4 and Responds in Vitro to a Small Molecule CCR4 Antagonist, CCR4-351

B. Hilda Ye, Eric Liu, Kith Pradhan, Erik Guillen, Urvi A Shah, Aditi Shastri, Gregoire Lauvau, Murali Janakiram, Alejandro Sica, Paul D. Kassner, Amit Verma
Journal: Blood
Blood (2023) 142 (Supplement 1): 6108.
https://doi.org/10.1182/blood-2023-191045
Published: 2023
Journal Articles

Acetyl Transferase EP300 Deficiency Leads to Chronic Replication Stress in Adult T-Cell Leukemia/Lymphoma

Mrunmai Niljikar, Aastha Juwarwala, Julia Gagliardi, Ranran Zhang, B. Hilda Ye, Advaitha Madireddy
Journal: Blood
Blood (2023) 142 (Supplement 1): 1404.
https://doi.org/10.1182/blood-2023-187061
Published: 2023
Journal Articles

Adult T-Cell Leukemia/Lymphoma Diagnosed in North American Is Characterized By a Requirement for BCL6 and a Cell Cycle Program Associated with DNA Replication Stress

B. Hilda Ye, Elaine Chung, Xiaoxin Ren, Kith Pradhan, Yanhua Wang, Advaitha Madireddy, Xingxing Zang, Murali Janakiram, R. Alejandro Sica, Amit Verma
Journal: Blood
Blood (2022) 140 (Supplement 1): 8764–8765.
https://doi.org/10.1182/blood-2022-170425
Published: 2022
Journal Articles

The Cause and Consequence of Replication Stress in Adult T-Cell Leukemia

Angelica Barreto-Galvez, Advaitha Madireddy, B. Hilda Ye, Julia Gagliardi, Aastha Juwarwala, Archana Pradeep, Mrunmai Niljikar
Journal: Blood
Blood (2022) 140 (Supplement 1): 11512.
https://doi.org/10.1182/blood-2022-167475
Published: 2022
Journal Articles

Allogeneic but Not Autologous Stem Cell Transplantation Improves Outcome in HTLV-1-Associated North American Adult T-Cell Leukemia/Lymphoma

Abdul-Hamid Bazarbachi, Daniel K. Reef, Hiba Narvel, Riya Patel, Rama Al Hamed, Astha Thakkar, Shafia Rahman, Urvi A Shah, Diego Adrianzen Herrera, Ryann Quinn, Sumaira Zareef, Emma Rabinovich, Alyssa De Castro, Felisha Joseph, Kailyn Gillick, Jennat Mustafa, Fariha Khatun, Amanda Lombardo, Latoya Townsend Nugent, Michelly Abreu, Nicole Chambers, Richard Elkind, Yang Shi, Yanhua Wang, Olga Derman, Kira Gritsman, Ulrich Steidl, Mendel Goldfinger, Noah Kornblum, Aditi Shastri, Ioannis Mantzaris, Lizamarie Bachier Rodriguez, Nishi Shah, Dennis Cooper, Ira Braunschweig, Amit Verma, B. Hilda Ye, Murali Janakiram, R. Alejandro Sica
Journal: Blood
Blood (2022) 140 (Supplement 1): 662–664.
https://doi.org/10.1182/blood-2022-170332
Published: 2022
Journal Articles

Whole-genome landscape of adult T-cell leukemia/lymphoma

Yasunori Kogure, Takuro Kameda, Junji Koya, Makoto Yoshimitsu, Kisato Nosaka, Jun-ichirou Yasunaga, Yoshitaka Imaizumi, Mizuki Watanabe, Yuki Saito, Yuta Ito, Marni B. McClure, Mariko Tabata, Sumito Shingaki, Kota Yoshifuji, Kenichi Chiba, Ai Okada, Nobuyuki Kakiuchi, Yasuhito Nannya, Ayako Kamiunten, Yuki Tahira, Keiichi Akizuki, Masaaki Sekine, Kotaro Shide, Tomonori Hidaka, Yoko Kubuki, Akira Kitanaka, Michihiro Hidaka, Nobuaki Nakano, Atae Utsunomiya, R. Alejandro Sica, Ana Acuna-Villaorduna, Murali Janakiram, Urvi Shah, Juan Carlos Ramos, Tatsuhiro Shibata, Kengo Takeuchi, Akifumi Takaori-Kondo, Yasushi Miyazaki, Masao Matsuoka, Kenji Ishitsuka, Yuichi Shiraishi, Satoru Miyano, Seishi Ogawa, B. Hilda Ye, Kazuya Shimoda, Keisuke Kataoka
Journal: Blood
Blood (2022) 139 (7): 967–982.
https://doi.org/10.1182/blood.2021013568
Published: 2022
Includes: Supplemental data
Journal Articles

Predictors of Central Nervous System (CNS) Involvement in North American Adult T-Cell Leukemia Lymphoma (ATLL) and Their Survival Pattern

Riya Patel, Shafia Rahman, Nishi Shah, Astha Thakkar, Ana Acuna-Villaorduna, Urvi A Shah, Diego Adrianzen Herrera, Alyssa De Castro, Jennat Mustafa, Fariha Khatun, Amanda Lombardo, Latoya Townsend Nugent, Yanhua Wang, Olga Derman, Shira Slasky, Kira Gritsman, Ulrich G. Steidl, Mendel Goldfinger, Noah Kornblum, Aditi Shastri, Ioannis Mantzaris, Lizamarie Bachier-Rodriguez, Ira Braunschweig, Amit Verma, Katharine McNeill, B. Hilda Ye, Murali Janakiram, R. Alejandro Sica
Journal: Blood
Blood (2021) 138 (Supplement 1): 1400.
https://doi.org/10.1182/blood-2021-151447
Published: 2021
Journal Articles

Allogeneic Stem Cell Transplantation in a Large Urban Cohort of North-American Adult T-Cell Leukemia/Lymphoma

Astha Thakkar, MBBS, Diego Adrianzen Herrera, MD, Shafia Rahman, MD, Zhu Cui, MD, Angelica D'Aiello, Amanda Lombardo, PA-C, BS, MS, Fariha Khatun, PA-C, Jennat Mustafa, PA-C, Kailyn Gillick, PA-C, Felisha Joseph, PA-C, Anjali Naik, PA-C, Latoya Townsend Nugent, NP, Nicole Chambers, ANP/FNP, Rosmi Mathew, FNP-BC, Michelly Abreu, ANP,MSN, Richard Elkind, PA-C, MS, Henrietta Noicely, RN, MSN, FNP, CNL, Ruby Yusay, BSN, RN, Carlo Palesi, Randin Nelson, MD, Donika Binakaj, BBA, Ulrich G. Steidl, MDPhD, Olga Derman, MD, Kira Gritsman, MDPhD, Noah Kornblum, MD, Ioannis Mantzaris, MD MS, Aditi Shastri, MD, Mendel Goldfinger, MD, Lizamarie Bachier-Rodriguez, MD, B. Hilda Ye, PhD, Amit Verma, MBBS, Ira Braunschweig, MD, Murali Janakiram, R. Alejandro Sica, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 21–22.
https://doi.org/10.1182/blood-2020-140812
Published: 2020
Journal Articles

Whole-Genome Analysis of Adult T-Cell Leukemia/Lymphoma

Yasunori Kogure, MD PhD, Takuro Kameda, MD PhD, Junji Koya, PhD MD, Ayako Kamiunten, MD, Kotaro Shide, MD PhD, Tomonori Hidaka, MD, Yoko Kubuki, MD PhD, Makoto Yoshimitsu, MD PhD, Kisato Nosaka, MD PhD, Yoshitaka Imaizumi, MD PhD, Mizuki Watanabe, MD, Yuki Saito, MD, Marni B McClure, MD PhD, Mariko Tabata, MD, Sumito Shingaki, PhD MD, Kota Yoshifuji, MD, Yuichi Shiraishi, PhD, Michihiro Hidaka, MD PhD, Atae Utsunomiya, MD, Urvi A. Shah, MD, Ana Acuna-Villaorduna, MD, Aditi Shastri, MD, R. Alejandro Sica, MD, Murali Janakiram, MD, Juan Carlos Ramos, MD BS, Tatsuhiro Shibata, MD PhD, Akifumi Takaori-Kondo, MD PhD, Yasushi Miyazaki, MD PhD, Masao Matsuoka, MDPhD, Kenji Ishitsuka, MD PhD, Seishi Ogawa, MD PhD, B. Hilda Ye, PhD, Kazuya Shimoda, MD PhD, Keisuke Kataoka, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 29–30.
https://doi.org/10.1182/blood-2020-134360
Published: 2020
Journal Articles

Prognostic Factors for North American Adult T Cell Leukemia Lymphoma: Defining Risk Groups Using a Four-Point Score Prognostic System

Shafia Rahman, MD, Alvaro Alvarez Soto, MD, Lindor Qunaj, MD, Kenny Ye, Kith Pradhan, PhD, Astha Thakkar, MBBS, Zhu Cui, MD, Michal Kasher Meron, Angelica D'Aiello, Amanda Lombardo, PA-C, BS, MS, Jennat Mustafa, PA-C, Fariha Khatun, PA-C, Kailyn Gillick, PA-C, Felisha Joseph, PA-C, Anjali Naik, PA-C, Alyssa De Castro, PharmD, Ulrich G. Steidl, MDPhD, Hao Wang, MS, Xiaoxin Ren, Xingxing Zang, PhD, Olga Derman, MD, Kira Gritsman, MDPhD, Noah Kornblum, MD, Aditi Shastri, MD, Ioannis Mantzaris, MD MS, Mendel Goldfinger, MD, Ira Braunschweig, MD, B. Hilda Ye, PhD, Amit Verma, MBBS, Murali Janakiram, MD, Urvi A Shah, MD, R. Alejandro Sica, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 38–39.
https://doi.org/10.1182/blood-2020-141428
Published: 2020
Journal Articles

Understanding the Mechanisms Driving Genomic Instability in Adult T-Cell Leukemia/Lymphoma

Advaitha Madireddy, PhD, Angelica Barreto-Galvez, B. Hilda Ye, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5042.
https://doi.org/10.1182/blood-2019-121565
Published: 2019
Journal Articles

S-Phase Progression of North American ATLL Cells Is Critically Regulated By the Proto-Oncogene BCL6 and Targetable By PARP Inhibition

B. Hilda Ye, PhD, Elaine Chung, PhD, Kith Pradhan, PhD, Ana Acuna-Villaorduna, MD, Yanhua Wang, MD PhD, Aditi Shastri, MD, Advaitha Madireddy, PhD, Amit Verma, MBBS, R.Alejandro Sica, MD, Murali Janakiram, MD MS
Journal: Blood
Blood (2019) 134 (Supplement_1): 3779.
https://doi.org/10.1182/blood-2019-131364
Published: 2019
Journal Articles

Conventional Chemotherapy Treatment Induces Unique Patterns of Clonal Evolution in a North American Adult T Cell Leukemia/Lymphoma Cohort

R. Alejandro Sica, MD, Nishi Shah, MBBS, MPH, Ana Acuna-Villaorduna, MD, Nivetha Vishnuvardan, MD, Urvi A Shah, MD, Diego Adrianzen Herrera, MD, Alyssa De Castro, PharmD, Jennat Mustafa, PA-C, Amanda Lombardo, PA-C, BS, MS, Fariha Khatun, PA-C, Latoya Townsend Nugent, NP, Yanhua Wang, MD PhD, Olga Derman, MD, Noah Kornblum, MD, Ioannis Mantzaris, MD MS, Lizamarie Bachier-Rodriguez, MD, Aditi Shastri, MD, Kira Gritsman, MD PhD, Ulrich G. Steidl, MD PhD, Ira Braunschweig, MD, Amit Verma, MBBS, Murali Janakiram, MD MS, B. Hilda Ye, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1551.
https://doi.org/10.1182/blood-2019-131107
Published: 2019
Journal Articles

Rapid progression of adult T-cell leukemia/lymphoma as tumor-infiltrating Tregs after PD-1 blockade

Daniel A. Rauch, Kevin C. Conlon, Murali Janakiram, Jonathan E. Brammer, John C. Harding, B. Hilda Ye, Xingxing Zang, Xiaoxin Ren, Sydney Olson, Xiaogang Cheng, Milos D. Miljkovic, Hemalatha Sundaramoorthi, Ancy Joseph, Zachary L. Skidmore, Obi Griffith, Malachi Griffith, Thomas A. Waldmann, Lee Ratner
Journal: Blood
Blood (2019) 134 (17): 1406–1414.
https://doi.org/10.1182/blood.2019002038
Published: 2019
Includes: Supplemental data
Journal Articles

Differentiating Lung Involvement in Adult T-Cell Leukemia Lymphoma (ATLL) Versus HTLV Infection: Results from a Large Single-Center Cohort with Implications for Staging and Response Criteria

Ana Acuna-Villaorduna, MD, Jesus D Gonzalez-Lugo, B. Hilda Ye, PhD, Urvi A Shah, MD, Gurbakhash Kaur, MDMA,BS, Nishi Shah, MBBS, MPH, Ioannis Mantzaris, MD MS, Aditi Shastri, MD, Ira Braunschweig, MD, Noah Kornblum, MD, Olga Derman, MD, Amit Verma, MD, Benjamin Zalta, MD, Murali Janakiram, MD MS
Journal: Blood
Blood (2018) 132 (Supplement 1): 1630.
https://doi.org/10.1182/blood-2018-99-119294
Published: 2018
Journal Articles

The Rising Number of Adult T Cell Leukemia Lymphoma (ATLL) Cases in Non-Hispanic Blacks and Its Association with Poor Outcomes

Urvi A Shah, MD, Nishi Shah, MBBS, MPH, Baozhen Qiao, PhD, Ana Acuna Villaorduna, MD, Aditi Shastri, MD, Ioannis Mantzaris, MD MS, Olga Derman, MD, Noah Kornblum, MD, Ira Braunschweig, MD, B. Hilda Ye, PhD, Amit Verma, MD, Murali Janakiram, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1642.
https://doi.org/10.1182/blood-2018-99-111721
Published: 2018
Journal Articles

Ras-Driven B-Cell Transformation Targets Developmental Rewiring of Cytokine to Pre-B Cell Receptor Signaling

Lai N Chan, Christian Hurtz, PhD, Huimin Geng, PhD, Franziska Auer, PhD, Zhengshan Chen, MDPhD, Gang Xiao, PhD, Jae-Woong Lee, PhD, Kadriye Nehir Cosgun, PhD, B Hilda Ye, PhD, Markus Muschen, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1336.
https://doi.org/10.1182/blood-2018-99-115514
Published: 2018
Journal Articles

North American ATLL has a distinct mutational and transcriptional profile and responds to epigenetic therapies

Urvi A. Shah, Elaine Y. Chung, Orsi Giricz, Kith Pradhan, Keisuke Kataoka, Shanisha Gordon-Mitchell, Tushar D. Bhagat, Yun Mai, Yongqiang Wei, Elise Ishida, Gaurav S. Choudhary, Ancy Joseph, Ronald Rice, Nadege Gitego, Crystall Parrish, Matthias Bartenstein, Swati Goel, Ioannis Mantzaris, Aditi Shastri, Olga Derman, Adam Binder, Kira Gritsman, Noah Kornblum, Ira Braunschweig, Chirag Bhagat, Jeff Hall, Armin Graber, Lee Ratner, Yanhua Wang, Seishi Ogawa, Amit Verma, B. Hilda Ye, Murali Janakiram
Journal: Blood
Blood (2018) 132 (14): 1507–1518.
https://doi.org/10.1182/blood-2018-01-824607
Published: 2018
Includes: Supplemental data
Journal Articles

SOX11 augments BCR signaling to drive MCL-like tumor development

Pei-Yu Kuo, Shashidhar S. Jatiani, Adeeb H. Rahman, Donna Edwards, Zewei Jiang, Katya Ahr, Deepak Perumal, Violetta V. Leshchenko, Joshua Brody, Rita Shaknovich, B. Hilda Ye, Samir Parekh
Journal: Blood
Blood (2018) 131 (20): 2247–2255.
https://doi.org/10.1182/blood-2018-02-832535
Published: 2018
Includes: Supplemental data
Journal Articles

BCL6 Enables RAS-Driven Pre-B Cell Transformation in Acute Lymphoblastic Leukemia

Lai N Chan, Christian Hurtz, PhD, Rebecca Caesar, Seyedmehdi Shojaee, PhD, Gang Xiao, PhD, Huimin Geng, PhD, Mignon L. Loh, MD, B. Hilda Ye, PhD, Steven Kornblau, MD, Markus Muschen, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1211.
https://doi.org/10.1182/blood.V130.Suppl_1.1211.1211
Published: 2017