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Journal Articles

TYK2 Is Essential for IFNα-Induced Resolution of MPN Features in a Murine Jak2 V617F PMF Model

Yuki Tahira, Kotaro Shide, Takuro Kameda, Ayako Kamiunten, Keiichi Akizuki, Masayoshi Karasawa, Ryoma Ikeda, Kengo Matsumoto, Yoko Kubuki, Kazuya Shimoda

Blood (2023) 142 (Supplement 1): 864.

https://doi.org/10.1182/blood-2023-181335

Published: 2023

Journal Articles

The Association between Blood Cell Counts and Thrombotic Events in Japanese Patients with Polycythemia Vera: A Retrospective Database Study

Kazuya Shimoda, Hideo Yasunaga, Yuka Sugimoto, Hidetoshi Uenaka, Takeo Dochi, Gyungjin Jun

Blood (2023) 142 (Supplement 1): 3191.

https://doi.org/10.1182/blood-2023-182706

Published: 2023

Journal Articles

Phase 1/2 Study of TP-3654, a Selective PIM1 Kinase Inhibitor: Preliminary Data Showed Clinical Activity and Cytokine Reductions in Relapsed/Refractory Myelofibrosis Patients

Blood (2023) 142 (Supplement 1): 626.

https://doi.org/10.1182/blood-2023-180164

Published: 2023

Journal Articles

Thrombotic and Bleeding Events in Japanese Adolescent and Young Adult PV and ET: Results from Japanese Multicenter Retrospective Study

Blood (2023) 142 (Supplement 1): 1831.

https://doi.org/10.1182/blood-2023-180561

Published: 2023

Journal Articles

Preliminary Data from the Phase I/II Study of TP-3654, a Selective Oral PIM1 Kinase Inhibitor, in Patients with Myelofibrosis Previously Treated with or Ineligible for JAK Inhibitor Therapy

Firas El Chaer, James McCloskey, Lindsay A.M. Rein, Randy A. Brown, Steven D. Green, Jeffrey J. Pu, Shuichi Shirane, Kazuya Shimoda, Michiko Ichii, Junichiro Yuda, Joseph Scandura, Sujan Kabir, Jason M Foulks, Jian Mei, Huyuan Yang, Mark Wade, Carl Stapinski, Claudia Lebedinsky, Raajit K Rampal

Blood (2022) 140 (Supplement 1): 594–595.

https://doi.org/10.1182/blood-2022-159086

Published: 2022

Journal Articles

Preclinical Translational Research Suggests a Clinical Trial Strategy for a Novel MALT1 Inhibitor ONO-7018/CTX-177 Against Malignant Lymphomas

Daisuke Morishita, Akio Mizutani, Hiroko Yamakawa, Yasuyoshi Arikawa, Hirokazu Tozaki, Takuro Kameda, Ayako Kamiunten, Keisuke Kataoka, Akinori Yoda, Yotaro Ochi, Kotaro Shide, Koji Izutsu, Yosuke Minami, Kazuya Shimoda, Seishi Ogawa

Blood (2022) 140 (Supplement 1): 8874–8875.

https://doi.org/10.1182/blood-2022-171019

Published: 2022

Journal Articles

Whole-genome landscape of adult T-cell leukemia/lymphoma

Blood (2022) 139 (7): 967–982.

https://doi.org/10.1182/blood.2021013568

Published: 2022

Includes: Supplemental data

Journal Articles

Dissecting Multicellular Ecosystems of HTLV-1 Infection and ATL By Multi-Omics Single Cell Analysis

Junji Koya, MD, Yuki Saito, MD, Takuro Kameda, MD, PhD, Yasunori Kogure, MD PhD, Marni B McClure, MD PhD, Sumito Shingaki, PhD MD, Mariko Tabata, MD, Ayako Kamiunten, MD, Kotaro Shide, MD PhD, Kazuya Shimoda, MD PhD, Keisuke Kataoka, MD PhD

Blood (2020) 136 (Supplement 1): 18.

https://doi.org/10.1182/blood-2020-141755

Published: 2020

Journal Articles

CARD11 Mutation Induces Oligoclonal Expansion of T-Cells, and Accelerates ATL Development in Combination with HBZ

Takuro Kameda, MD PhD, Kotaro Shide, MD PhD, Ayako Kamiunten, MD, Tahira Yuki, Masaaki Sekine, MD, Keiichi Akizuki, MD, Tomonori Hidaka, MD, Yoko Kubuki, MD PhD, Midori Sugiyama, Daisuke Morishita, PhD, Kazuya Shimoda, MD PhD

Blood (2020) 136 (Supplement 1): 17–18.

https://doi.org/10.1182/blood-2020-142242

Published: 2020

Journal Articles

Preclinical Evaluation of a Novel MALT1 Inhibitor CTX-177 for Relapse/Refractory Lymphomas

Daisuke Morishita, PhD, Akio Mizutani, PhD, Hirokazu Tozaki, PhD, Yasuyoshi Arikawa, PhD, Takuro Kameda, MD PhD, Ayako Kamiunten, MD, Keisuke Kataoka, MD PhD, Akinori Yoda, PhD, Yotaro Ochi, MD, Kotaro Shide, MD PhD, Koji Izutsu, MD PhD, Yosuke Minami, MDPhD, Kazuya Shimoda, MD PhD, Hiroshi Miyake, PhD, Seishi Ogawa, MD PhD

Blood (2020) 136 (Supplement 1): 3–4.

https://doi.org/10.1182/blood-2020-141824

Published: 2020

Journal Articles

The Rationale, Design, and Baseline Characteristics of a Phase 2 Study to Evaluate the Safety and Efficacy of Ropeginterferon Alfa-2b (P1101) in Japanese Patients with Polycythemia Vera for Whom the Current Standard of Care Is Difficult to Apply

Keita Kirito, MD, Kazuya Shimoda, MD PhD, Katsuto Takenaka, MD PhD, Albert Qin, MD PhD, Oleh Zagrijtschuk, MD, Toshiaki Sato, MD PhD, Narihisa Miyachi, Hiroaki Kawase, Katsuya Yonezu, Norio Komatsu, MD PhD

Blood (2020) 136 (Supplement 1): 24–25.

https://doi.org/10.1182/blood-2020-142504

Published: 2020

Journal Articles

Impact of COVID19 Pandemic on an International MPN Patient Population: Survey Results from 1560 MPN Patients

Blood (2020) 136 (Supplement 1): 1–3.

https://doi.org/10.1182/blood-2020-138953

Published: 2020

Journal Articles

Whole-Genome Analysis of Adult T-Cell Leukemia/Lymphoma

Blood (2020) 136 (Supplement 1): 29–30.

https://doi.org/10.1182/blood-2020-134360

Published: 2020

Journal Articles

Human erythroleukemia genetics and transcriptomes identify master transcription factors as functional disease drivers

Blood (2020) 136 (6): 698–714.

https://doi.org/10.1182/blood.2019003062

Published: 2020

Includes: Supplemental data

Journal Articles

Calreticulin haploinsufficiency augments stem cell activity and is required for onset of myeloproliferative neoplasms in mice

Kotaro Shide, Takuro Kameda, Ayako Kamiunten, Yoshinori Ozono, Yuki Tahira, Takako Yokomizo-Nakano, Sho Kubota, Masaya Ono, Kazuhiko Ikeda, Masaaki Sekine, Keiichi Akizuki, Kenichi Nakamura, Tomonori Hidaka, Yoko Kubuki, Hisayoshi Iwakiri, Satoru Hasuike, Kenji Nagata, Goro Sashida, Kazuya Shimoda

Blood (2020) 136 (1): 106–118.

https://doi.org/10.1182/blood.2019003358

Published: 2020

Includes: Supplemental data

Journal Articles

Dynamic and Time-to-Event Analyses Demonstrate Marked Reduction in Transfusion Requirements for Janus Kinase Inhibitor-Naïve Myelofibrosis Patients Treated with Momelotinib Compared Head to Head with Ruxolitinib

Ruben A Mesa, MD, John Catalano, MBBS, FRACP, FRCPA, Francisco Cervantes, MD, Timothy Devos, MD PhD, Jason Gotlib, MD MS, Jean-Jacques Kiladjian, MD PhD, Donal P. McLornan, MB, BCh (Hons), MRCP, PhD FRCPath, Kazuya Shimoda, MD PhD, Elisabeth Coart, PhD, Koenraad D'Hollander, MD MSC, Rafe Donahue, PhD, Mark M Kowalski, MD PhD

Blood (2019) 134 (Supplement_1): 1663.

https://doi.org/10.1182/blood-2019-122506

Published: 2019

Journal Articles

The Role of Calreticulin in Normal Hematopoiesis and Neoplastic Hematopoiesis of Myeloproliferative Neoplasms

Kotaro Shide, MD PhD, Takuro Kameda, MD PhD, Ayako Kamiunten, MD, Yoshinori Ozono, MD, Yuki Tahira, MD, Masaaki Sekine, MD, Masaya Ono, MD PhD, Takako Yokomizo, PhD, Sho Kubota, Keiichi Akizuki, MD, Yoko Kubuki, MD PhD, Tomonori Hidaka, MD, Goro Sashida, MD PhD, Kazuya Shimoda, MD PhD

Blood (2019) 134 (Supplement_1): 309.

https://doi.org/10.1182/blood-2019-130034

Published: 2019

Journal Articles

Depletion of Neoplastic CD11b Positive Cells in Jak2 V617F Mutant Mice Reduced Fibrocytes in Bone Marrow and Improved Myelofibrosis

Yoshinori Ozono, MD, Kotaro Shide, MD PhD, Takuro Kameda, MD PhD, Ayako Kamiunten, MD, Yuki Tahira, MD, Masaaki Sekine, MD, Keiichi Akizuki, MD, Kenichi Nakamura, MD, Hisayoshi Iwakiri, MD, Tomonori Hidaka, MD, Yoko Kubuki, MD PhD, Satoru Hasuike, MD PhD, Fumiyo Toyoshima, MD PhD, Akira Sawaguchi, MD PhD, Kenji Nagata, MD PhD, Kazuya Shimoda, MD PhD

Blood (2019) 134 (Supplement_1): 310.

https://doi.org/10.1182/blood-2019-130042

Published: 2019

Journal Articles

Vitamin D receptor–mediated skewed differentiation of macrophages initiates myelofibrosis and subsequent osteosclerosis

Kanako Wakahashi, Kentaro Minagawa, Yuko Kawano, Hiroki Kawano, Tomohide Suzuki, Shinichi Ishii, Akiko Sada, Noboru Asada, Mari Sato, Shigeaki Kato, Kotaro Shide, Kazuya Shimoda, Toshimitsu Matsui, Yoshio Katayama

Blood (2019) 133 (15): 1619–1629.

https://doi.org/10.1182/blood-2018-09-876615

Published: 2019

Includes: Supplemental data

Journal Articles

Haploinsufficiency of CALR Confers Hematopoietic Stem Cells (HSCs) with a Clonal Advantage over Wild-Type Cells, and, in Setting of Myeloproliferative Neoplasms, Compensates for the Functions of HSCs Impaired By the Calr Mutation

Kotaro Shide, MD PhD, Takuro Kameda, MD, Ayako Kamiunten, MD, Masaaki Sekine, MD, Yoshinori Ozono, MD, Takako Yokomizo, PhD, Keiichi Akizuki, MD, Yuki Tahira, MD, Yoko Kubuki, MD PhD, Tomonori Hidaka, MD, Goro Sashida, MD PhD, Kazuya Shimoda, MD PhD

Blood (2018) 132 (Supplement 1): 97.

https://doi.org/10.1182/blood-2018-99-114304

Published: 2018

NARROW

TYK2 Is Essential for IFNα-Induced Resolution of MPN Features in a Murine Jak2 V617F PMF Model

The Association between Blood Cell Counts and Thrombotic Events in Japanese Patients with Polycythemia Vera: A Retrospective Database Study

Phase 1/2 Study of TP-3654, a Selective PIM1 Kinase Inhibitor: Preliminary Data Showed Clinical Activity and Cytokine Reductions in Relapsed/Refractory Myelofibrosis Patients

Thrombotic and Bleeding Events in Japanese Adolescent and Young Adult PV and ET: Results from Japanese Multicenter Retrospective Study

Preliminary Data from the Phase I/II Study of TP-3654, a Selective Oral PIM1 Kinase Inhibitor, in Patients with Myelofibrosis Previously Treated with or Ineligible for JAK Inhibitor Therapy

Preclinical Translational Research Suggests a Clinical Trial Strategy for a Novel MALT1 Inhibitor ONO-7018/CTX-177 Against Malignant Lymphomas

Whole-genome landscape of adult T-cell leukemia/lymphoma

Dissecting Multicellular Ecosystems of HTLV-1 Infection and ATL By Multi-Omics Single Cell Analysis

CARD11 Mutation Induces Oligoclonal Expansion of T-Cells, and Accelerates ATL Development in Combination with HBZ

Preclinical Evaluation of a Novel MALT1 Inhibitor CTX-177 for Relapse/Refractory Lymphomas

The Rationale, Design, and Baseline Characteristics of a Phase 2 Study to Evaluate the Safety and Efficacy of Ropeginterferon Alfa-2b (P1101) in Japanese Patients with Polycythemia Vera for Whom the Current Standard of Care Is Difficult to Apply

Impact of COVID19 Pandemic on an International MPN Patient Population: Survey Results from 1560 MPN Patients

Whole-Genome Analysis of Adult T-Cell Leukemia/Lymphoma

Human erythroleukemia genetics and transcriptomes identify master transcription factors as functional disease drivers

Calreticulin haploinsufficiency augments stem cell activity and is required for onset of myeloproliferative neoplasms in mice

Dynamic and Time-to-Event Analyses Demonstrate Marked Reduction in Transfusion Requirements for Janus Kinase Inhibitor-Naïve Myelofibrosis Patients Treated with Momelotinib Compared Head to Head with Ruxolitinib

The Role of Calreticulin in Normal Hematopoiesis and Neoplastic Hematopoiesis of Myeloproliferative Neoplasms

Depletion of Neoplastic CD11b Positive Cells in Jak2 V617F Mutant Mice Reduced Fibrocytes in Bone Marrow and Improved Myelofibrosis

Vitamin D receptor–mediated skewed differentiation of macrophages initiates myelofibrosis and subsequent osteosclerosis

Haploinsufficiency of CALR Confers Hematopoietic Stem Cells (HSCs) with a Clonal Advantage over Wild-Type Cells, and, in Setting of Myeloproliferative Neoplasms, Compensates for the Functions of HSCs Impaired By the Calr Mutation

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American Society of Hematology

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ASH Publications

American Society of Hematology

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