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Journal Articles

Comparative evaluation of ipss-m and cpss-mol in CMML: Impact of molecular markers on prognosis

Alexander Streuer, Yotaro Ochi, Yasuhito Nannya, Laurenz Steiner, Vladimir Riabov, Mohammed Abba, Eva Altrock, Felicitas Rapp, Verena Nowak, Georgia Metzgeroth, Seishi Ogawa, Wolf-Karsten Hofmann, Nanni Schmitt

Blood (2025) 146 (Supplement 1): 3860.

https://doi.org/10.1182/blood-2025-3860

Published: 2025

Journal Articles

Functional classification of monoallelic TP53 mutations refines prognostic stratification in myelodysplastic neoplasms

Alexander Streuer, Vladimir Riabov, Yotaro Ochi, Yasuhito Nannya, Laurenz Steiner, Mohammed Abba, Georgia Metzgeroth, Eva Altrock, Felicitas Rapp, Verena Nowak, Daniel Nowak, Seishi Ogawa, Wolf-Karsten Hofmann, Nanni Schmitt

Blood (2025) 146 (Supplement 1): 3835.

https://doi.org/10.1182/blood-2025-3835

Published: 2025

Journal Articles

Single-cell multiomic profiling of gene mutation, chromatin accessibility, and gene expression in TET2-mutant clonal hematopoiesis

Masanori Motomura, Yotaro Ochi, Yasuhito Nannya, Nobuyuki Kakiuchi, Nobuo Sezaki, Senji Kasahara, Tomoe Nakagawa, Lanying Zhao, Shuichi Matsuda, Masahiro Nakagawa, Seishi Ogawa

Blood (2025) 146 (Supplement 1): 3164.

https://doi.org/10.1182/blood-2025-3164

Published: 2025

Journal Articles

Repertoire of driver events in coding and non-coding regions identified by whole-genome sequencing of myeloid neoplasms

Blood (2025) 146 (Supplement 1): 1450.

https://doi.org/10.1182/blood-2025-1450

Published: 2025

Journal Articles

Bone marrow environmental alterations underlie proliferative clonal expansion in clonal hematopoiesis

Masahiro Nakagawa, Ryosaku Inagaki, Yasuhito Nannya, Masanori Motomura, Ryunosuke Saiki, Yotaro Ochi, Ayana Kon, Lanying Zhao, Koji Okazaki, Xingxing Qi, Akinori Yoda, Nobuyuki Kakiuchi, Shuichi Matsuda, Seishi Ogawa

Blood (2025) 146 (Supplement 1): 632.

https://doi.org/10.1182/blood-2025-632

Published: 2025

Journal Articles

Single-cell multi-omics uncovers differentiation-dependent transcriptional programs shaping epigenetic subgroups in AML

Blood (2025) 146 (Supplement 1): 5005.

https://doi.org/10.1182/blood-2025-5005

Published: 2025

Journal Articles

SLF2 and SMC5 are novel causative genes for inherited bone marrow failure syndromes, driving HSC aging and predisposing to MDS

Sho Shibata, Kazuhisa Chonabayashi, Hirofumi Nakamura, Akitsu Hotta, Yuri Uchiyama, Yukiko Oh, Naomichi Matsumoto, Yotaro Ochi, Seishi Ogawa, Akifumi Takaori-Kondo, Yoshinori Yoshida

Blood (2025) 146 (Supplement 1): 4989.

https://doi.org/10.1182/blood-2025-4989

Published: 2025

Journal Articles

Molecular Taxonomy Classification for Transplant Decision Making of Myelodysplastic Syndromes

Rurika Okuda, Yotaro Ochi, Tetsuichi Yoshizato, Yasuhito Nannya, Yoshiko Atsuta, Yuichi Shiraishi, Yusuke Shiozawa, Hiroko Tanaka, Makoto Onizuka, Kenichi Chiba, Hidehiro Itonaga, Yoshinobu Kanda, Yasushi Miyazaki, Keizo Horibe, Satoru Miyano, Hideki Makishima, Seishi Ogawa

Blood (2024) 144 (Supplement 1): 3203.

https://doi.org/10.1182/blood-2024-206498

Published: 2024

Journal Articles

Deciphering the Heterogeneity of Acute Myeloid Leukemia through Chromatin Accessibility Profiling

Blood (2024) 144 (Supplement 1): 639.

https://doi.org/10.1182/blood-2024-200415

Published: 2024

Journal Articles

High-Throughput and Highly Sensitive Single Cell Genotyping with Simultaneous Chromatin Accessibility Measurement in Myeloid Precursor Conditions

Masanori Motomura, Yotaro Ochi, Masahiro M Nakagawa, Yasuhito Nannya, Nobuyuki Kakiuchi, Yutaka Kuroda, Nobuo Sezaki, Tomoe Nakagawa, Lanying Zhao, Satoru Miyano, Shuichi Matsuda, Seishi Ogawa

Blood (2024) 144 (Supplement 1): 5635.

https://doi.org/10.1182/blood-2024-206815

Published: 2024

Journal Articles

Distinct Pathogenesis of Clonal Hematopoiesis Revealed By Single-Cell Multi-Omics Sequencing

Masahiro M Nakagawa, Ryosaku Inagaki, Yutaka Kuroda, Yasuhito Nannya, Ayana Kon, Masanori Motomura, Yotaro Ochi, Lanying Zhao, Koji Okazaki, June Takeda, Xingxing Qi, Akinori Yoda, Nobuyuki Kakiuchi, Hideki Makishima, Shuichi Matsuda, Seishi Ogawa

Blood (2024) 144 (Supplement 1): 5630.

https://doi.org/10.1182/blood-2024-210050

Published: 2024

Journal Articles

Landscape of driver mutations and their clinical effects on Down syndrome–related myeloid neoplasms

Tomohiko Sato, Kenichi Yoshida, Tsutomu Toki, Rika Kanezaki, Kiminori Terui, Ryunosuke Saiki, Masami Ojima, Yotaro Ochi, Seiya Mizuno, Masaharu Yoshihara, Tamayo Uechi, Naoya Kenmochi, Shiro Tanaka, Jun Matsubayashi, Kenta Kisai, Ko Kudo, Kentaro Yuzawa, Yuka Takahashi, Tatsuhiko Tanaka, Yohei Yamamoto, Akie Kobayashi, Takuya Kamio, Shinya Sasaki, Yuichi Shiraishi, Kenichi Chiba, Hiroko Tanaka, Hideki Muramatsu, Asahito Hama, Daisuke Hasegawa, Atsushi Sato, Katsuyoshi Koh, Shuhei Karakawa, Masao Kobayashi, Junichi Hara, Yuichi Taneyama, Chihaya Imai, Daiichiro Hasegawa, Naoto Fujita, Masahiro Yoshitomi, Shotaro Iwamoto, Genki Yamato, Satoshi Saida, Nobutaka Kiyokawa, Takao Deguchi, Masafumi Ito, Hidemasa Matsuo, Souichi Adachi, Yasuhide Hayashi, Takashi Taga, Akiko M. Saito, Keizo Horibe, Kenichiro Watanabe, Daisuke Tomizawa, Satoru Miyano, Satoru Takahashi, Seishi Ogawa, Etsuro Ito

Blood (2024) 143 (25): 2627–2643.

https://doi.org/10.1182/blood.2023022247

Published: 2024

Includes: Supplemental data

Journal Articles

Canonical BAF complex regulates the oncogenic program in human T-cell acute lymphoblastic leukemia

Kazunari Aoki, Mizuki Hyuga, Yusuke Tarumoto, Gohei Nishibuchi, Atsushi Ueda, Yotaro Ochi, Seiichi Sugino, Takashi Mikami, Hirokazu Kobushi, Itaru Kato, Koshi Akahane, Takeshi Inukai, Akifumi Takaori-Kondo, Junko Takita, Seishi Ogawa, Kosuke Yusa

Blood (2024) 143 (7): 604–618.

https://doi.org/10.1182/blood.2023020857

Published: 2024

Includes: Supplemental data

Journal Articles

Epigenetic Classification of Acute Myeloid Leukemia Revealed By Genome-Wide Chromatin Profiling

Blood (2023) 142 (Supplement 1): 836.

https://doi.org/10.1182/blood-2023-180336

Published: 2023

Journal Articles

Clonal Evolution of Der(1;7)(q10;p10) Myeloid Neoplasms

Blood (2023) 142 (Supplement 1): 1000.

https://doi.org/10.1182/blood-2023-185857

Published: 2023

Journal Articles

Germ line DDX41 mutations define a unique subtype of myeloid neoplasms

Hideki Makishima, Ryunosuke Saiki, Yasuhito Nannya, Sophia Korotev, Carmelo Gurnari, June Takeda, Yukihide Momozawa, Steve Best, Pramila Krishnamurthy, Tetsuichi Yoshizato, Yoshiko Atsuta, Yusuke Shiozawa, Yuka Iijima-Yamashita, Kenichi Yoshida, Yuichi Shiraishi, Yasunobu Nagata, Nobuyuki Kakiuchi, Makoto Onizuka, Kenichi Chiba, Hiroko Tanaka, Ayana Kon, Yotaro Ochi, Masahiro M. Nakagawa, Rurika Okuda, Takuto Mori, Akinori Yoda, Hidehiro Itonaga, Yasushi Miyazaki, Masashi Sanada, Takayuki Ishikawa, Shigeru Chiba, Hisashi Tsurumi, Senji Kasahara, Carsten Müller-Tidow, Akifumi Takaori-Kondo, Kazuma Ohyashiki, Toru Kiguchi, Fumihiko Matsuda, Joop H. Jansen, Chantana Polprasert, Piers Blombery, Yoichiro Kamatani, Satoru Miyano, Luca Malcovati, Torsten Haferlach, Michiaki Kubo, Mario Cazzola, Austin G. Kulasekararaj, Lucy A. Godley, Jaroslaw P. Maciejewski, Seishi Ogawa

Blood (2023) 141 (5): 534–549.

https://doi.org/10.1182/blood.2022018221

Published: 2023

Includes: Supplemental data

Journal Articles

Distinct Pathogenesis of Clonal Hematopoiesis Revealed By Single Cell RNA Sequencing Integrated with Highly Sensitive Genotyping Method

Masahiro Marshall Nakagawa, Ryosaku Inagaki, Yutaka Kuroda, Yasuhito Nannya, Lanying Zhao, Yotaro Ochi, June Takeda, Qi Xingxing, Akinori Yoda, Ayana Kon, Nobuyuki Kakiuchi, Hideki Makishima, Shuichi Matsuda, Seishi Ogawa

Blood (2022) 140 (Supplement 1): 2881–2882.

https://doi.org/10.1182/blood-2022-168149

Published: 2022

Journal Articles

Preclinical Translational Research Suggests a Clinical Trial Strategy for a Novel MALT1 Inhibitor ONO-7018/CTX-177 Against Malignant Lymphomas

Daisuke Morishita, Akio Mizutani, Hiroko Yamakawa, Yasuyoshi Arikawa, Hirokazu Tozaki, Takuro Kameda, Ayako Kamiunten, Keisuke Kataoka, Akinori Yoda, Yotaro Ochi, Kotaro Shide, Koji Izutsu, Yosuke Minami, Kazuya Shimoda, Seishi Ogawa

Blood (2022) 140 (Supplement 1): 8874–8875.

https://doi.org/10.1182/blood-2022-171019

Published: 2022

Journal Articles

Molecular Landscape of Myeloid Neoplasms with Der(1;7)(q10;p10)

Blood (2022) 140 (Supplement 1): 6902–6904.

https://doi.org/10.1182/blood-2022-168213

Published: 2022

Journal Articles

Cooperative Effects of SRSF2 and STAG2 mutations on Development of Myelodysplastic Syndrome and Its Related Disorders

Blood (2022) 140 (Supplement 1): 4022–4023.

https://doi.org/10.1182/blood-2022-158748

Published: 2022

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Comparative evaluation of ipss-m and cpss-mol in CMML: Impact of molecular markers on prognosis

Functional classification of monoallelic TP53 mutations refines prognostic stratification in myelodysplastic neoplasms

Single-cell multiomic profiling of gene mutation, chromatin accessibility, and gene expression in TET2-mutant clonal hematopoiesis

Repertoire of driver events in coding and non-coding regions identified by whole-genome sequencing of myeloid neoplasms

Bone marrow environmental alterations underlie proliferative clonal expansion in clonal hematopoiesis

Single-cell multi-omics uncovers differentiation-dependent transcriptional programs shaping epigenetic subgroups in AML

SLF2 and SMC5 are novel causative genes for inherited bone marrow failure syndromes, driving HSC aging and predisposing to MDS

Molecular Taxonomy Classification for Transplant Decision Making of Myelodysplastic Syndromes

Deciphering the Heterogeneity of Acute Myeloid Leukemia through Chromatin Accessibility Profiling

High-Throughput and Highly Sensitive Single Cell Genotyping with Simultaneous Chromatin Accessibility Measurement in Myeloid Precursor Conditions

Distinct Pathogenesis of Clonal Hematopoiesis Revealed By Single-Cell Multi-Omics Sequencing

Landscape of driver mutations and their clinical effects on Down syndrome–related myeloid neoplasms

Canonical BAF complex regulates the oncogenic program in human T-cell acute lymphoblastic leukemia

Epigenetic Classification of Acute Myeloid Leukemia Revealed By Genome-Wide Chromatin Profiling

Clonal Evolution of Der(1;7)(q10;p10) Myeloid Neoplasms

Germ line DDX41 mutations define a unique subtype of myeloid neoplasms

Distinct Pathogenesis of Clonal Hematopoiesis Revealed By Single Cell RNA Sequencing Integrated with Highly Sensitive Genotyping Method

Preclinical Translational Research Suggests a Clinical Trial Strategy for a Novel MALT1 Inhibitor ONO-7018/CTX-177 Against Malignant Lymphomas

Molecular Landscape of Myeloid Neoplasms with Der(1;7)(q10;p10)

Cooperative Effects of SRSF2 and STAG2 mutations on Development of Myelodysplastic Syndrome and Its Related Disorders

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American Society of Hematology

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American Society of Hematology

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