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Journal Articles

Landscape of driver mutations and their clinical effects on Down syndrome–related myeloid neoplasms

Tomohiko Sato, Kenichi Yoshida, Tsutomu Toki, Rika Kanezaki, Kiminori Terui, Ryunosuke Saiki, Masami Ojima, Yotaro Ochi, Seiya Mizuno, Masaharu Yoshihara, Tamayo Uechi, Naoya Kenmochi, Shiro Tanaka, Jun Matsubayashi, Kenta Kisai, Ko Kudo, Kentaro Yuzawa, Yuka Takahashi, Tatsuhiko Tanaka, Yohei Yamamoto, Akie Kobayashi, Takuya Kamio, Shinya Sasaki, Yuichi Shiraishi, Kenichi Chiba, Hiroko Tanaka, Hideki Muramatsu, Asahito Hama, Daisuke Hasegawa, Atsushi Sato, Katsuyoshi Koh, Shuhei Karakawa, Masao Kobayashi, Junichi Hara, Yuichi Taneyama, Chihaya Imai, Daiichiro Hasegawa, Naoto Fujita, Masahiro Yoshitomi, Shotaro Iwamoto, Genki Yamato, Satoshi Saida, Nobutaka Kiyokawa, Takao Deguchi, Masafumi Ito, Hidemasa Matsuo, Souichi Adachi, Yasuhide Hayashi, Takashi Taga, Akiko M. Saito, Keizo Horibe, Kenichiro Watanabe, Daisuke Tomizawa, Satoru Miyano, Satoru Takahashi, Seishi Ogawa, Etsuro Ito

Blood (2024) 143 (25): 2627–2643.

https://doi.org/10.1182/blood.2023022247

Published: 2024

Includes: Supplemental data

Journal Articles

Clonal germinal center B cells function as a niche for T-cell lymphoma

Blood (2022) 140 (18): 1937–1950.

https://doi.org/10.1182/blood.2022015451

Published: 2022

Includes: Supplemental data

Journal Articles

Germinal Center B Cells Derived from TET2 -Mutated Clonal Hematopoiesis Provide a Microenviromental Niche for Tumor Cells in Angioimmunoblastic T-Cell Lymphoma

Manabu Fujisawa, Tran B. Nguyen, Yoshiaki Abe, Yasuhito Suehara, Kota Fukumoto, Sakurako Suma, Kensuke Usuki, Kentaro Narita, Kosei Matsue, Naoya Nakamura, Shumpei Ishikawa, Fumihito Miura, Takashi Ito, Ayako Suzuki, Yutaka Suzuki, Satoru Takahashi, Shigeru Chiba, Mamiko Sakata-Yanagimoto

Blood (2021) 138 (Supplement 1): 445.

https://doi.org/10.1182/blood-2021-149983

Published: 2021

Journal Articles

FGF-23 from erythroblasts promotes hematopoietic progenitor mobilization

Shinichi Ishii, Tomohide Suzuki, Kanako Wakahashi, Noboru Asada, Yuko Kawano, Hiroki Kawano, Akiko Sada, Kentaro Minagawa, Yukio Nakamura, Seiya Mizuno, Satoru Takahashi, Toshimitsu Matsui, Yoshio Katayama

Blood (2021) 137 (11): 1457–1467.

https://doi.org/10.1182/blood.2020007172

Published: 2021

Includes: Supplemental data

Journal Articles

The chromatin-binding protein Phf6 restricts the self-renewal of hematopoietic stem cells

Satoru Miyagi, Patrycja Sroczynska, Yuko Kato, Yaeko Nakajima-Takagi, Motohiko Oshima, Ola Rizq, Naoya Takayama, Atsunori Saraya, Seiya Mizuno, Fumihiro Sugiyama, Satoru Takahashi, Yumi Matsuzaki, Jesper Christensen, Kristian Helin, Atsushi Iwama

Blood (2019) 133 (23): 2495–2506.

https://doi.org/10.1182/blood.2019000468

Published: 2019

Includes: Supplemental data

Journal Articles

Notch Signaling in Bone Marrow Nestin-Expressing Cells Controls Balance of Erythropoiesis at the Bone Marrow and Spleen

Tatsuhiro Sakamoto, MD, Naoshi Obara, MDPhD, Takayasu Kato, MD PhD, Luan Cao Sy, Hidekazu Nishikii, MD PhD, Mamiko Sakata-Yanagimoto, MD PhD, Satoru Takahashi, MDPhD, Shigeru Chiba, MD, PhD

Blood (2016) 128 (22): 432.

https://doi.org/10.1182/blood.V128.22.432.432

Published: 2016

Journal Articles

T-cell–restricted T-bet overexpression induces aberrant hematopoiesis of myeloid cells and impairs function of macrophages in the lung

Shoichi Iriguchi, Norihiro Kikuchi, Shin Kaneko, Emiko Noguchi, Yuko Morishima, Masashi Matsuyama, Keigyou Yoh, Satoru Takahashi, Hiromitsu Nakauchi, Yukio Ishii

Blood (2015) 125 (2): 370–382.

https://doi.org/10.1182/blood-2014-05-575225

Published: 2015

Includes: Supplemental data

Journal Articles

C1galt1-deficient mice exhibit thrombocytopenia due to abnormal terminal differentiation of megakaryocytes

Takashi Kudo, Takashi Sato, Kozue Hagiwara, Yukinori Kozuma, Takashi Yamaguchi, Yuzuru Ikehara, Michito Hamada, Ken Matsumoto, Masatsugu Ema, Soichiro Murata, Nobuhiro Ohkohchi, Hisashi Narimatsu, Satoru Takahashi

Blood (2013) 122 (9): 1649–1657.

https://doi.org/10.1182/blood-2012-12-471102

Published: 2013

Journal Articles

Genome-wide identification of endothelial cell–enriched genes in the mouse embryo

Haruka Takase, Ken Matsumoto, Rie Yamadera, Yoshiaki Kubota, Ayaka Otsu, Rumiko Suzuki, Hiroyuki Ishitobi, Hiromi Mochizuki, Takahiro Kojima, Shingo Takano, Kazuhiko Uchida, Satoru Takahashi, Masatsugu Ema

Blood (2012) 120 (4): 914–923.

https://doi.org/10.1182/blood-2011-12-398156

Published: 2012

Includes: Supplemental data

Journal Articles

c-Maf plays a crucial role for the definitive erythropoiesis that accompanies erythroblastic island formation in the fetal liver

Manabu Kusakabe, Kazuteru Hasegawa, Michito Hamada, Megumi Nakamura, Takayuki Ohsumi, Hirona Suzuki, Tran Thi Nhu Mai, Takashi Kudo, Kazuhiko Uchida, Haruhiko Ninomiya, Shigeru Chiba, Satoru Takahashi

Blood (2011) 118 (5): 1374–1385.

https://doi.org/10.1182/blood-2010-08-300400

Published: 2011

Includes: Supplemental data

Journal Articles

Functional Analysis of Transcription Factor c-Maf in Embryonic Hematopoiesis.

Manabu Kusakabe, MD, Michito Hamada, PhD, Megumi Nakamura, Takashi Kudo, PhD, Haruhiko Ninomiya, MD, PhD, Satoru Takahashi, MD, PhD

Blood (2009) 114 (22): 3646.

https://doi.org/10.1182/blood.V114.22.3646.3646

Published: 2009

Journal Articles

Loss of the Gata1 Gene IE Exon Leads to Variant Transcript Expression and the Production of GATA1 Protein Lacking the N-Terminal Domain.

Eri Kobayashi, Ritsuko Shimizu, Yuko Kikuchi, Satoru Takahashi, Masayuki Yamamoto, MD, PhD

Blood (2009) 114 (22): 3648.

https://doi.org/10.1182/blood.V114.22.3648.3648

Published: 2009

Journal Articles

Gene expression profile of the third pharyngeal pouch reveals role of mesenchymal MafB in embryonic thymus development

Dil Afroz Sultana, Shuhei Tomita, Michito Hamada, Yasuyuki Iwanaga, Yuki Kitahama, Nguyen Van Khang, Shuichi Hirai, Izumi Ohigashi, Sachiko Nitta, Takashi Amagai, Satoru Takahashi, Yousuke Takahama

Blood (2009) 113 (13): 2976–2987.

https://doi.org/10.1182/blood-2008-06-164921

Published: 2009

Includes: Supplemental data

Journal Articles

Runx1 is involved in primitive erythropoiesis in the mouse

Tomomasa Yokomizo, Kazuteru Hasegawa, Hiroyuki Ishitobi, Motomi Osato, Masatsugu Ema, Yoshiaki Ito, Masayuki Yamamoto, Satoru Takahashi

Blood (2008) 111 (8): 4075–4080.

https://doi.org/10.1182/blood-2007-05-091637

Published: 2008

Journal Articles

Primitive erythropoiesis from mesodermal precursors expressing VE-cadherin, PECAM-1, Tie2, endoglin, and CD34 in the mouse embryo

Masatsugu Ema, Tomomasa Yokomizo, Asami Wakamatsu, Tsumoru Terunuma, Masayuki Yamamoto, Satoru Takahashi

Blood (2006) 108 (13): 4018–4024.

https://doi.org/10.1182/blood-2006-03-012872

Published: 2006

Includes: Supplemental data

Journal Articles

Deletion of the selection cassette, but not cis -acting elements, in targeted Flk1-lacZ allele reveals Flk1 expression in multipotent mesodermal progenitors

Masatsugu Ema, Satoru Takahashi, Janet Rossant

Blood (2006) 107 (1): 111–117.

https://doi.org/10.1182/blood-2005-05-1970

Published: 2006

Journal Articles

mafB Deficient Mouse Results in Impaired Macrophage Differentiation.

Michito Hamada, Takashi Moriguchi, Naoki Morito, Chuan Zhang, Kazuteru Hasegawa, Keigyou Yoh, Etsushi Kuroda, Tomomasa Yokomizo, James D. Engel, Masayuki Yamamoto, Satoru Takahashi

Blood (2005) 106 (11): 2222.

https://doi.org/10.1182/blood.V106.11.2222.2222

Published: 2005

Journal Articles

Oral administration of K-11706 inhibits GATA binding activity, enhances hypoxia-inducible factor 1 binding activity, and restores indicators in an in vivo mouse model of anemia of chronic disease

Yoko Nakano, Shigehiko Imagawa, Ken Matsumoto, Christian Stockmann, Naoshi Obara, Norio Suzuki, Takeshi Doi, Tatsuhiko Kodama, Satoru Takahashi, Toshiro Nagasawa, Masayuki Yamamoto

Blood (2004) 104 (13): 4300–4307.

https://doi.org/10.1182/blood-2004-04-1631

Published: 2004

Journal Articles

Expression and domain-specific function of GATA-2 during differentiation of the hematopoietic precursor cells in midgestation mouse embryos

Naoko Minegishi, Norio Suzuki, Tomomasa Yokomizo, Xiaoqing Pan, Tetsuhiro Fujimoto, Satoru Takahashi, Takahiko Hara, Atsushi Miyajima, Shin-ichi Nishikawa, Masayuki Yamamoto

Blood (2003) 102 (3): 896–905.

https://doi.org/10.1182/blood-2002-12-3809

Published: 2003

Journal Articles

Erythroid-specific expression of the erythropoietin receptor rescued its null mutant mice from lethality

Norio Suzuki, Osamu Ohneda, Satoru Takahashi, Masato Higuchi, Harumi Y. Mukai, Tatsutoshi Nakahata, Shigehiko Imagawa, Masayuki Yamamoto

Blood (2002) 100 (7): 2279–2288.

https://doi.org/10.1182/blood-2002-01-0124

Published: 2002

NARROW

Landscape of driver mutations and their clinical effects on Down syndrome–related myeloid neoplasms

Clonal germinal center B cells function as a niche for T-cell lymphoma

Germinal Center B Cells Derived from TET2 -Mutated Clonal Hematopoiesis Provide a Microenviromental Niche for Tumor Cells in Angioimmunoblastic T-Cell Lymphoma

FGF-23 from erythroblasts promotes hematopoietic progenitor mobilization

The chromatin-binding protein Phf6 restricts the self-renewal of hematopoietic stem cells

Notch Signaling in Bone Marrow Nestin-Expressing Cells Controls Balance of Erythropoiesis at the Bone Marrow and Spleen

T-cell–restricted T-bet overexpression induces aberrant hematopoiesis of myeloid cells and impairs function of macrophages in the lung

C1galt1-deficient mice exhibit thrombocytopenia due to abnormal terminal differentiation of megakaryocytes

Genome-wide identification of endothelial cell–enriched genes in the mouse embryo

c-Maf plays a crucial role for the definitive erythropoiesis that accompanies erythroblastic island formation in the fetal liver

Functional Analysis of Transcription Factor c-Maf in Embryonic Hematopoiesis.

Loss of the Gata1 Gene IE Exon Leads to Variant Transcript Expression and the Production of GATA1 Protein Lacking the N-Terminal Domain.

Gene expression profile of the third pharyngeal pouch reveals role of mesenchymal MafB in embryonic thymus development

Runx1 is involved in primitive erythropoiesis in the mouse

Primitive erythropoiesis from mesodermal precursors expressing VE-cadherin, PECAM-1, Tie2, endoglin, and CD34 in the mouse embryo

Deletion of the selection cassette, but not cis -acting elements, in targeted Flk1-lacZ allele reveals Flk1 expression in multipotent mesodermal progenitors

mafB Deficient Mouse Results in Impaired Macrophage Differentiation.

Oral administration of K-11706 inhibits GATA binding activity, enhances hypoxia-inducible factor 1 binding activity, and restores indicators in an in vivo mouse model of anemia of chronic disease

Expression and domain-specific function of GATA-2 during differentiation of the hematopoietic precursor cells in midgestation mouse embryos

Erythroid-specific expression of the erythropoietin receptor rescued its null mutant mice from lethality

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American Society of Hematology

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American Society of Hematology

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