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Journal Articles

Targeting Mitochondrial Apoptotic Priming State to Personalize Therapy for Relapsed Acute Myeloid Leukemia

Blood (2023) 142 (Supplement 1): 48.

https://doi.org/10.1182/blood-2023-189156

Published: 2023

Journal Articles

Core-binding factor fusion downregulation of ADAR2 RNA editing contributes to AML leukemogenesis

Blood (2023) 141 (25): 3078–3090.

https://doi.org/10.1182/blood.2022015830

Published: 2023

Includes: Supplemental data

Journal Articles

HMGA2 Maintains Hematopoietic Stem Cell Via Pleiotropic Regulation of the Transcription in Stress Conditions

Sho Kubota, Yuqi Sun, Jie Bai, Takako Yokomizo-Nakano, Mariko Morii, Takako Ideue, Motomi Osato, Terumasa Umemoto, Kimi Araki, Goro Sashida

Blood (2021) 138 (Supplement 1): 3262.

https://doi.org/10.1182/blood-2021-152472

Published: 2021

Journal Articles

Hematopoietic stem cells acquire survival advantage by loss of RUNX1 methylation identified in familial leukemia

Takayoshi Matsumura, Ayako Nakamura-Ishizu, Siva Sai Naga Anurag Muddineni, Darren Qiancheng Tan, Chelsia Qiuxia Wang, Kenji Tokunaga, Roberto Tirado-Magallanes, Stephanie Sian, Touati Benoukraf, Tsukasa Okuda, Norio Asou, Masao Matsuoka, Motomi Osato, Toshio Suda

Blood (2020) 136 (17): 1919–1932.

https://doi.org/10.1182/blood.2019004292

Published: 2020

Includes: Supplemental data

Journal Articles

Lysine acetyltransferase Tip60 is required for hematopoietic stem cell maintenance

Blood (2020) 136 (15): 1735–1747.

https://doi.org/10.1182/blood.2019001279

Published: 2020

Includes: Supplemental data

Journal Articles

Lineage-Specific RUNX2 Super-Enhancer Activates MYC Via Translocation (6;8) to Promote the Development of Blastic Plasmacytoid Dendritic Cell Neoplasm

Sho Kubota, PhD, Kenji Tokunaga, MD, Tomohiro Umezu, PhD, Takako Yokomizo, PhD, Motohiko Oshima, PhD, Eisaku Iwanaga, MD PhD, Norio Asou, MDPhD, Atsushi Iwama, MD PhD, Kazuma Ohyashiki, MD PhD, Motomi Osato, MD, PhD, Goro Sashida, MD PhD

Blood (2018) 132 (Supplement 1): 761.

https://doi.org/10.1182/blood-2018-99-110333

Published: 2018

Journal Articles

ASLAN003, a Novel and Potent Dihydroorotate Dehydrogenase (DHODH) Inhibitor, Induces Differentiation of Acute Myeloid Leukemia

Jianbiao Zhou, MD,PhD, Jessie Yiying Quah, B.S., Jing Yuan Chooi, BSc, Sabrina Hui-Min Toh, B.S., Yvonne Ng, B.S., Baohong Lin, B.S., Motomi Osato, MD, PhD, Qihui Seet, B.S., PhD, A.G. Lisa Ooi, B.S., PhD, Bertil Lindmark, MD PhD, Mark McHale, B.S., PhD, Wee Joo Chng, MB ChB, PhD FRCP(UK), FRCPath, FAMS

Blood (2018) 132 (Supplement 1): 4047.

https://doi.org/10.1182/blood-2018-99-114392

Published: 2018

Journal Articles

RUNX3 Promotes the Development of MDS/MPN Overlap Syndrome Via Enhancing Expression of Myc in the Absence of Tet2

Takako Yokomizo, PhD, Daiki Tanaka, Sho Kubota, PhD, Motohiko Oshima, PhD, Yuka Harada, MD PhD, Akinori Kanai, PhD, Atsushi Iwama, MD PhD, Hironori Harada, Motomi Osato, MD PhD, Goro Sashida, MD PhD

Blood (2017) 130 (Supplement 1): 2494.

https://doi.org/10.1182/blood.V130.Suppl_1.2494.2494

Published: 2017

Journal Articles

A Runx1 Interactome Identifies Novel Hematopoietic Enhancers

Judith Marsman, PhD, Amarni L Thomas, MSc, Motomi Osato, MD PhD, Justin M O'Sullivan, PhD, Julia A Horsfield, PhD

Blood (2016) 128 (22): 726.

https://doi.org/10.1182/blood.V128.22.726.726

Published: 2016

Journal Articles

An unsung runt 6e isoform for HSC expansion

Motomi Osato

Blood (2014) 123 (24): 3684–3686.

https://doi.org/10.1182/blood-2014-05-572891

Published: 2014

Journal Articles

Runx3 deficiency results in myeloproliferative disorder in aged mice

Chelsia Qiuxia Wang, Lena Motoda, Masanobu Satake, Yoshiaki Ito, Ichiro Taniuchi, Vinay Tergaonkar, Motomi Osato

Blood (2013) 122 (4): 562–566.

https://doi.org/10.1182/blood-2012-10-460618

Published: 2013

Includes: Supplemental data

Journal Articles

The ability of MLL to bind RUNX1 and methylate H3K4 at PU.1 regulatory regions is impaired by MDS/AML-associated RUNX1/AML1 mutations

Gang Huang, Xinghui Zhao, Lan Wang, Shannon Elf, Hao Xu, Xinyang Zhao, Goro Sashida, Yue Zhang, Yan Liu, Jennifer Lee, Silvia Menendez, Youyang Yang, Xiaomei Yan, Pu Zhang, Daniel G. Tenen, Motomi Osato, James J.-D. Hsieh, Stephen D. Nimer

Blood (2011) 118 (25): 6544–6552.

https://doi.org/10.1182/blood-2010-11-317909

Published: 2011

Includes: Supplemental data

Journal Articles

Three-dimensional imaging of whole midgestation murine embryos shows an intravascular localization for all hematopoietic clusters

Tomomasa Yokomizo, Cherry Ee Lin Ng, Motomi Osato, Elaine Dzierzak

Blood (2011) 117 (23): 6132–6134.

https://doi.org/10.1182/blood-2011-02-334037

Published: 2011

Includes: Multimedia, Supplemental data

Journal Articles

Stem cell exhaustion due to Runx1 deficiency is prevented by Evi5 activation in leukemogenesis

Bindya Jacob, Motomi Osato, Namiko Yamashita, Chelsia Qiuxia Wang, Ichiro Taniuchi, Dan R. Littman, Norio Asou, Yoshiaki Ito

Blood (2010) 115 (8): 1610–1620.

https://doi.org/10.1182/blood-2009-07-232249

Published: 2010

Includes: Supplemental data

Journal Articles

Expression profiling of a hemopoietic cell survival transcriptome implicates osteopontin as a functional prognostic factor in AML

Blood (2009) 114 (23): 4859–4870.

https://doi.org/10.1182/blood-2009-02-204818

Published: 2009

Includes: Supplemental data

Journal Articles

Expression Profiling of a Hemopoietic Cell Survival Transcriptome Identifies a Functional Prognostic Gene Signature in Normal Karyotype AML.

Mark Guthridge, Daniel Thomas, MD, Emma F Barry, Kok H Chung, Barbara J McClure, L. Bik To, MD, Greg Goodall, Terry P Speed, Motomi Osato, David Haylock, Susie Nilsson, MD, Richard D'Andrea, PhD, Angel Lopez, Jason A Powell, PhD

Blood (2009) 114 (22): 1618.

https://doi.org/10.1182/blood.V114.22.1618.1618

Published: 2009

Journal Articles

Runx1 is involved in primitive erythropoiesis in the mouse

Tomomasa Yokomizo, Kazuteru Hasegawa, Hiroyuki Ishitobi, Motomi Osato, Masatsugu Ema, Yoshiaki Ito, Masayuki Yamamoto, Satoru Takahashi

Blood (2008) 111 (8): 4075–4080.

https://doi.org/10.1182/blood-2007-05-091637

Published: 2008

Journal Articles

The zebrafish udu gene encodes a novel nuclear factor and is essential for primitive erythroid cell development

Yanmei Liu, Linsen Du, Motomi Osato, Eng Hui Teo, Feng Qian, Hao Jin, Fenghua Zhen, Jin Xu, Lin Guo, Honghui Huang, Jun Chen, Robert Geisler, Yun-Jin Jiang, Jinrong Peng, Zilong Wen

Blood (2007) 110 (1): 99–106.

https://doi.org/10.1182/blood-2006-11-059204

Published: 2007

Includes: Supplemental data

Journal Articles

Concurrent transcriptional deregulation of AML1/RUNX1 and GATA factors by the AML1-TRPS1 chimeric gene in t(8;21)(q24;q22) acute myeloid leukemia

Norio Asou, Masatoshi Yanagida, Liqun Huang, Masayuki Yamamoto, Katsuya Shigesada, Hiroaki Mitsuya, Yoshiaki Ito, Motomi Osato

Blood (2007) 109 (9): 4023–4027.

https://doi.org/10.1182/blood-2006-01-031781

Published: 2007

Includes: Supplemental data

Journal Articles

Identification of Marker Genes That Discriminate between Different Myeloproliferative Disorders and Normal Individuals Including RUNX3 (AML2).

Claudia I. Muller, MD, Quang T. Luong, PhD, Letetia C. Jones, PhD, Julian C. Desmond, PhD, Norihiko Kawamata, MD, PhD, Tcherniantchouk Tcherniantchouk, MD, Lee-Yung Shih, MD, Yoshiaki Ito, MD, PhD, Kosei Ito, PhD, Qiang Liu, PhD, Motomi Osato, MD, PhD, Sven de Vos, MD, H. Phillip Koeffler, MD

Blood (2005) 106 (11): 3522.

https://doi.org/10.1182/blood.V106.11.3522.3522

Published: 2005

NARROW

Targeting Mitochondrial Apoptotic Priming State to Personalize Therapy for Relapsed Acute Myeloid Leukemia

Core-binding factor fusion downregulation of ADAR2 RNA editing contributes to AML leukemogenesis

HMGA2 Maintains Hematopoietic Stem Cell Via Pleiotropic Regulation of the Transcription in Stress Conditions

Hematopoietic stem cells acquire survival advantage by loss of RUNX1 methylation identified in familial leukemia

Lysine acetyltransferase Tip60 is required for hematopoietic stem cell maintenance

Lineage-Specific RUNX2 Super-Enhancer Activates MYC Via Translocation (6;8) to Promote the Development of Blastic Plasmacytoid Dendritic Cell Neoplasm

ASLAN003, a Novel and Potent Dihydroorotate Dehydrogenase (DHODH) Inhibitor, Induces Differentiation of Acute Myeloid Leukemia

RUNX3 Promotes the Development of MDS/MPN Overlap Syndrome Via Enhancing Expression of Myc in the Absence of Tet2

A Runx1 Interactome Identifies Novel Hematopoietic Enhancers

An unsung runt 6e isoform for HSC expansion

Runx3 deficiency results in myeloproliferative disorder in aged mice

The ability of MLL to bind RUNX1 and methylate H3K4 at PU.1 regulatory regions is impaired by MDS/AML-associated RUNX1/AML1 mutations

Three-dimensional imaging of whole midgestation murine embryos shows an intravascular localization for all hematopoietic clusters

Stem cell exhaustion due to Runx1 deficiency is prevented by Evi5 activation in leukemogenesis

Expression profiling of a hemopoietic cell survival transcriptome implicates osteopontin as a functional prognostic factor in AML

Expression Profiling of a Hemopoietic Cell Survival Transcriptome Identifies a Functional Prognostic Gene Signature in Normal Karyotype AML.

Runx1 is involved in primitive erythropoiesis in the mouse

The zebrafish udu gene encodes a novel nuclear factor and is essential for primitive erythroid cell development

Concurrent transcriptional deregulation of AML1/RUNX1 and GATA factors by the AML1-TRPS1 chimeric gene in t(8;21)(q24;q22) acute myeloid leukemia

Identification of Marker Genes That Discriminate between Different Myeloproliferative Disorders and Normal Individuals Including RUNX3 (AML2).

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American Society of Hematology

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ASH Publications

American Society of Hematology

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