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Journal Articles

Selective targeting of mutated calreticulin by the monoclonal antibody INCA033989 inhibits oncogenic function of MPN

Blood blood.2024024373.

https://doi.org/10.1182/blood.2024024373

Published: 2024

Includes: Supplemental data

Journal Articles

TREM2 acts as a receptor for IL-34 to suppress acute myeloid leukemia in mice

Blood (2023) 141 (26): 3184–3198.

https://doi.org/10.1182/blood.2022018619

Published: 2023

Includes: Supplemental data

Journal Articles

Discovery of INCA033989, a Monoclonal Antibody That Selectively Antagonizes Mutant Calreticulin Oncogenic Function in Myeloproliferative Neoplasms (MPNs)

Edimara Reis, Rebecca Buonpane, Hamza Celik, Caroline Marty, Angela Lei, Fatoumata Jobe, Mark Rupar, Yue Zhang, Darlise DiMatteo, Rahel Awdew, William Vainchenker, Jing Zhou, Ian Hitchcock, Isabelle Plo, Horacio Nastri, Patrick Mayes

Blood (2022) 140 (Supplement 1): 14–15.

https://doi.org/10.1182/blood-2022-159435

Published: 2022

Journal Articles

CAR-T Cell Therapy of Solid Tumors Invokes an Expanded Set of Myeloid Cells in an Orthotopic Tumor Model for Rhabdomyosarcoma

Peter Sullivan, Yue Zhang, Virginia Hoglund, Sophie Jamet, Isela J Garcia, Rimas J Orentas

Blood (2022) 140 (Supplement 1): 10277–10278.

https://doi.org/10.1182/blood-2022-164779

Published: 2022

Journal Articles

CD22 CAR-T Induces Both CD19 and CD22 Surface Down-Modulation: Defining a Mechanism of Generalized Immune Evasion and the Effects of Epigenetic Modifiers

Lingyan Wang, PhDDVM, Yue Zhang, MS, Eden Anderson, BS, Rajesh Kumar, PhD, Adam J. Lamble, MD, Rimas J Orentas, PhD

Blood (2020) 136 (Supplement 1): 22–23.

https://doi.org/10.1182/blood-2020-134930

Published: 2020

Journal Articles

Myc Regulates the Development and Anti-Tumor Immunity of Natural Killer Cells

Yuting Tang, MD PhD, Xiaomei Yan, MD PhD, Di Zhan, PhD, Lijun Wen, MS, Rui Huang, MD PhD, Yue Zhang, MD PhD, Yoshihiro Hayashi, MD PhD, Qianfei Wang, PhD, Jianfeng Zhou, MD PhD, Gang Huang, PhD

Blood (2018) 132 (Supplement 1): 1113.

https://doi.org/10.1182/blood-2018-99-114180

Published: 2018

Journal Articles

HIF1A Is a Critical Downstream Mediator for Hemophagocytic Lymphohistiocytosis

Blood (2017) 130 (Supplement 1): 3565.

https://doi.org/10.1182/blood.V130.Suppl_1.3565.3565

Published: 2017

Journal Articles

Clinical Features and Biological Implications of U2AF1 Mutations in Myelodysplastic Syndromes

Bing Li, Jinqin Liu, Yujiao Jia, MD, Tiejun Qin, Zefeng Xu, MD, Yue Zhang, MD PhD, Gang Huang, PhD, Zhijian Xiao

Blood (2017) 130 (Supplement 1): 586.

https://doi.org/10.1182/blood.V130.Suppl_1.586.586

Published: 2017

Journal Articles

Essential Role of c-MYC for Natural Killer Cell Development, Proliferation and Anti-Tumor Activity

Yuting Tang, MD, Xiaomei Yan, Rui Huang, MD PhD, Yoshihiro Hayashi, MD PhD, Yue Zhang, Wang Qianfei, PhD, Jianfeng Zhou, MD PhD, Gang Huang, PhD

Blood (2017) 130 (Supplement 1): 786.

https://doi.org/10.1182/blood.V130.Suppl_1.786.786

Published: 2017

Journal Articles

Monotcytes/Macrophages Are Involved in Erythrocytosis Caused By Both EPO-Dependent and -Independent Activation of EPOR

Asumi Yokota, PhD, Yoshihiro Hayashi, MD PhD, Jieyu Wang, MD PhD, Rui Huang, MD PhD, Xiaomei Yan, Yue Zhang, MD PhD, Gang Huang, PhD

Blood (2017) 130 (Supplement 1): 449.

https://doi.org/10.1182/blood.V130.Suppl_1.449.449

Published: 2017

Journal Articles

Global Crosstalk between Two Histone Modifications That Control Transcriptional Elongation in MLL Leukemia

Jiachen Bu, Aili Chen, PhD, Xiaomei Yan, Fuhong He, PhD, Yunzhu Dong, Yile Zhou, Jianlin He, Yoshihiro Hayashi, Di Zhan, Yanling Sun, Yue Zhang, Zhijian Xiao, Lee Grimes, Qianfei Wang, PhD, Gang Huang, PhD

Blood (2017) 130 (Supplement 1): 2495.

https://doi.org/10.1182/blood.V130.Suppl_1.2495.2495

Published: 2017

Journal Articles

Platelet Transcriptomic Signatures in Myeloproliferative Neoplasms

Anandi Krishnan, PhD, Yue Zhang, PhD, Cecelia Perkins, Jason Gotlib, MD, James L. Zehnder, MD

Blood (2017) 130 (Supplement 1): 5288.

https://doi.org/10.1182/blood.V130.Suppl_1.5288.5288

Published: 2017

Journal Articles

Non-Driver Mutations Profile Identified By a 206-Gene NGS Panel in Patients with Primary Myelofibrosis and Post-Polycythaemic/Essential Thromocythaemia Myelofibrosis in a Single Center from China

Bing Li, MD, Lei Zhang, MD, Jie Bai, MD PhD, Zefeng Xu, MD, Tiejun Qin, Yue Zhang, MD, Jinqin Liu, Gang Huang, PhD, Zhijian Xiao, MD

Blood (2016) 128 (22): 1942.

https://doi.org/10.1182/blood.V128.22.1942.1942

Published: 2016

Journal Articles

EPO Signaling Triggers Erythrocytosis By Expanding Erythrocytes and Also Subsets of Macrophages

Yoshihiro Hayashi, MD PhD, Jieyu Wang, MD, Zefeng Xu, MD, Xiaomei Yan, MD PhD, Yue Zhang, MD, Theodosia A Kalfa, MD PhD, Zhijian Xiao, MD, Gang Huang, PhD

Blood (2016) 128 (22): 542.

https://doi.org/10.1182/blood.V128.22.542.542

Published: 2016

Journal Articles

Usp18 Is Required for Normal Stem Cell Maintenance

Kei-ichiro Arimoto, PhD, Yue Zhang, Ming Yan, PhD, Sayuri Miyauchi, DDS, PhD, Stephanie Weng, PhD, Samuel A. Stoner, Takahiro Shima, MD PhD, Yukiko Komeno, MD PhD, Kentson Lam, MD PhD, Dong-Er Zhang, PhD

Blood (2016) 128 (22): 3863.

https://doi.org/10.1182/blood.V128.22.3863.3863

Published: 2016

Journal Articles

Colony-Forming Unit Cell (CFU-C) Assays in Myelodysplastic Syndrome

Bing Li, MD, Jinqin Liu, Shiqiang Qu, MD, Robert Peter Gale, MD PhD DSc, Ruixian Xing, Tiejun Qin, Yue Zhang, MD, Zefeng Xu, MD, Liwei Fang, Hongli Zhang, MD, Lijuan Pan, Naibo Hu, Gang Huang, PhD, Zhijian Xiao, MD

Blood (2015) 126 (23): 2874.

https://doi.org/10.1182/blood.V126.23.2874.2874

Published: 2015

Journal Articles

A Novel Erythroid Regulator MLF1IP Promotes Proliferation in Mice By Regulating Cell Cycle

Tianjiao Zhang, MD, Xiaotang Ma, PhD, Bing Li, MD, Gang Huang, PhD, Robert Peter Gale, MD PhD DSc, Yue Zhang, MD, Zefeng Xu, MD, Tiejun Qin, Josef T. Prchal, MD, Zhijian Xiao, MD

Blood (2015) 126 (23): 2835.

https://doi.org/10.1182/blood.V126.23.2835.2835

Published: 2015

Journal Articles

Impact of Megakaryocyte Morphology on Prognosis of Persons with Myelodysplastic Syndromes

Gege Feng, MD, Wen Cui, Wenyu Cai, Tiejun Qin, Yue Zhang, MD, Zefeng Xu, MD, Liwei Fang, Hongli Zhang, MD, Lijuan Pan, Naibo Hu, Bing Li, MD, Zhijian Xiao, MD

Blood (2015) 126 (23): 2876.

https://doi.org/10.1182/blood.V126.23.2876.2876

Published: 2015

Journal Articles

Symptom Burden Profile in Myelofibrosis Patients with Thrombocytopenia: Lessons and Unmet Needs

Holly Geyer, MD, Robyn M Scherber, MD MPH, Heidi Kosiorek, Amylou C. Dueck, PhD, Jean-Jacques Kiladjian, MD PhD, Zhijian Xiao, MD, Stefanie Slot, Sonja Zweegman, MD PhD, Federico Sackmann, Ana Kerguelen Fuentes, Dolores Hernandez-Maraver, PhD, Konstanze Dohner, MD, Claire N. Harrison, Deepti Radia, Pablo J. Muxi, MD, Carlos Besses, Francisco Cervantes, Peter L. Johansson, MD PhD, Bjorn Andreasson, MDPhD, Alessandro Rambaldi, MD, Tiziano Barbui, MD, Karin Bonatz, Andreas Reiter, MD, Francoise Boyer, MD, Gabriel Etienne, MD PhD, Jean-Christophe Ianotto, MD, Dana Ranta, Lydia Roy, MD, Jean-Yves Cahn, Norman I Maldonado, MD, Giovanni Barosi, Maria Ferrari, Robert Peter Gale, MD PhD DSc, Gunnar Birgegard, MD PhD, Zefeng Xu, MD, Yue Zhang, MD, Xiujuan Sun, MD, Junqing Xu, Peihong Zhang, Peter te Boekhorst, Suzan Commandeur, Harry C. Schouten, MD PhD, Heike L Pahl, PhD, Martin Griesshammer, MD, Frank Stegelmann, MD, Thomas Lehmann, Alessandro M. Vannucchi, Francesco Passamonti, MD, Jan Samuelsson, MD PhD, Ruben A. Mesa, MD

Blood (2015) 126 (23): 4080.

https://doi.org/10.1182/blood.V126.23.4080.4080

Published: 2015

Journal Articles

HIF-1a Pathway, As a Signal Funnel for Genetic, Epigenetic, and Metabolic Aberrations, Is Sufficient and Essential for MDS Development

Blood (2015) 126 (23): 303.

https://doi.org/10.1182/blood.V126.23.303.303

Published: 2015

NARROW

Selective targeting of mutated calreticulin by the monoclonal antibody INCA033989 inhibits oncogenic function of MPN

TREM2 acts as a receptor for IL-34 to suppress acute myeloid leukemia in mice

Discovery of INCA033989, a Monoclonal Antibody That Selectively Antagonizes Mutant Calreticulin Oncogenic Function in Myeloproliferative Neoplasms (MPNs)

CAR-T Cell Therapy of Solid Tumors Invokes an Expanded Set of Myeloid Cells in an Orthotopic Tumor Model for Rhabdomyosarcoma

CD22 CAR-T Induces Both CD19 and CD22 Surface Down-Modulation: Defining a Mechanism of Generalized Immune Evasion and the Effects of Epigenetic Modifiers

Myc Regulates the Development and Anti-Tumor Immunity of Natural Killer Cells

HIF1A Is a Critical Downstream Mediator for Hemophagocytic Lymphohistiocytosis

Clinical Features and Biological Implications of U2AF1 Mutations in Myelodysplastic Syndromes

Essential Role of c-MYC for Natural Killer Cell Development, Proliferation and Anti-Tumor Activity

Monotcytes/Macrophages Are Involved in Erythrocytosis Caused By Both EPO-Dependent and -Independent Activation of EPOR

Global Crosstalk between Two Histone Modifications That Control Transcriptional Elongation in MLL Leukemia

Platelet Transcriptomic Signatures in Myeloproliferative Neoplasms

Non-Driver Mutations Profile Identified By a 206-Gene NGS Panel in Patients with Primary Myelofibrosis and Post-Polycythaemic/Essential Thromocythaemia Myelofibrosis in a Single Center from China

EPO Signaling Triggers Erythrocytosis By Expanding Erythrocytes and Also Subsets of Macrophages

Usp18 Is Required for Normal Stem Cell Maintenance

Colony-Forming Unit Cell (CFU-C) Assays in Myelodysplastic Syndrome

A Novel Erythroid Regulator MLF1IP Promotes Proliferation in Mice By Regulating Cell Cycle

Impact of Megakaryocyte Morphology on Prognosis of Persons with Myelodysplastic Syndromes

Symptom Burden Profile in Myelofibrosis Patients with Thrombocytopenia: Lessons and Unmet Needs

HIF-1a Pathway, As a Signal Funnel for Genetic, Epigenetic, and Metabolic Aberrations, Is Sufficient and Essential for MDS Development

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American Society of Hematology

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ASH Publications

American Society of Hematology

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