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Ian Hitchcock
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Journal Articles

Platelets Sequester Extracellular DNA, Capturing Tumour-Derived and Free Fetal DNA

Lauren Murphy, Jeanne Inchauspe, Nikolaos Sousos, Natalie Jooss, Hayley L Belnoue-Davis, Pamela Holland, Rong Li, Giampiero Valenzano, Fenella Roseman, Sujata Biswas, Sally-Ann Clark, Jennifer O'Sullivan, Michael Rimmer, Abdullah O Khan, Christina Simoglou Karali, Eric ONeill, Nadia Nasreddin, Ian Hitchcock, Milka Koupenova, Manu Vatish, Paul Rees, Simon Leedham, Adam J Mead, Benjamin Schuster-Boeckler, Christopher Gregory, Bethan Psaila
Journal: Blood
Blood (2023) 142 (Supplement 1): 277.
https://doi.org/10.1182/blood-2023-182697
Published: 2023
Journal Articles

Preclinical Evaluation of INCB160058 - a Novel and Potentially Disease-Modifying Therapy for JAK2V617F Mutant Myeloproliferative Neoplasms

Matthew C. Stubbs, Hamza Celik, Yanran Ai, Xin He, Hong Chang, Angela Lei, Mark Rupar, Brittney Wass, Melody Diamond, Xiaoming Wen, Jun Li, Nina Zolotarjova, Alex Margulis, Gaurang Trivedi, Angelo B.A. Laranjeira, Cooper A. Taylor, Jennifer Rocha, Christoph Pollmann, Jacob Piehler, Bianca L. Ferreira, Ian Hitchcock, Ricardo Macarrón, Eddy W. Yue, Sunkyu Kim
Journal: Blood
Blood (2023) 142 (Supplement 1): 860.
https://doi.org/10.1182/blood-2023-179369
Published: 2023
Journal Articles

Discovery of INCA033989, a Monoclonal Antibody That Selectively Antagonizes Mutant Calreticulin Oncogenic Function in Myeloproliferative Neoplasms (MPNs)

Edimara Reis, Rebecca Buonpane, Hamza Celik, Caroline Marty, Angela Lei, Fatoumata Jobe, Mark Rupar, Yue Zhang, Darlise DiMatteo, Rahel Awdew, William Vainchenker, Jing Zhou, Ian Hitchcock, Isabelle Plo, Horacio Nastri, Patrick Mayes
Journal: Blood
Blood (2022) 140 (Supplement 1): 14–15.
https://doi.org/10.1182/blood-2022-159435
Published: 2022
Journal Articles

An Adapting Bone Marrow Niche Creates a Nurturing Environment for Hematopoiesis during Immune Thrombocytopenia Progression

Oliver Herd, BSc, Maria Abril Arredondo Garcia, BSc, James Hewitson, PhD, Karen Hogg, PhD, Saleni Pravin Kumar, BSc, Katiuska Pulgar Prieto, BSc, Andrew Stone, BSc, Paul Genever, PhD, Ian Hitchcock, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 222.
https://doi.org/10.1182/blood-2019-129795
Published: 2019
Journal Articles

New Paradigms for the Mechanisms of Thrombopoietin Receptor Activation and Dysregulation By the JAK2 V617F Mutation

Stephan Wilmes, PhD, Maximillian Hafer, BSc, Tess A Stanly, Ignacio Moraga, PhD, Joni Vuorio, PhD, Chetan Poojari, PhD, Vivek Sharma, PhD, Sara Löchte, PhD, Katiuska Pulgar Prieto, BSc, Julie A Tucker, PhD, Stevan R Hubbard, PhD, K.Christopher Garcia, PhD, Ilpo Vattulainen, PhD, Ian Hitchcock, PhD, Jacob Piehler, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2962.
https://doi.org/10.1182/blood-2019-129234
Published: 2019
Journal Articles

Understanding the Mechanisms Underlying Thrombocytopenia in Visceral Leishmaniasis

Gulab Fatima Rani, MBBS, Olivier Preham, PhD, Ian Hitchcock, PhD, Paul Kaye, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2378.
https://doi.org/10.1182/blood-2019-128133
Published: 2019
Journal Articles

Thrombopoietin-Mediated Ubiquitination and Degradation of C-Mpl

Sebastian J Saur, Amy Geddis, MD, PhD, Kenneth Kaushansky, MD, Ian Hitchcock, PhD
Journal: Blood
Blood (2008) 112 (11): 2889.
https://doi.org/10.1182/blood.V112.11.2889.2889
Published: 2008
Journal Articles

Erythropoietin Stimulates Thrombopoiesis in the Absence of C-Mpl Signaling

Norma E Fox, BSc, Rose Chen, BSc, Ian Hitchcock, PhD, Kenneth Kaushansky, MD, Amy Geddis, MD, PhD
Journal: Blood
Blood (2008) 112 (11): 2451.
https://doi.org/10.1182/blood.V112.11.2451.2451
Published: 2008