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Angela Lei
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Journal Articles

Selective targeting of mutated calreticulin by the monoclonal antibody INCA033989 inhibits oncogenic function of MPN

Edimara Reis, Rebecca Buonpane, Hamza Celik, Caroline Marty, Angela Lei, Fatoumata Jobe, Mark Rupar, Yue Zhang, Darlise DiMatteo, Rahel Awdew, Bianca L Ferreira, Lynn Leffet, Lu Lu, Elodie Rosa, Maxime Evrard, Gaurang Trivedi, Brittney Wass, April Horsey, Xin He, Maryanne B Covington, Alla Volgina, Florence Pasquier, Laurence Legros, Guillemette Fouquet, William Vainchenker, Yan-ou Yang, Breann Barker, Jing Zhou, Shaun Stewart, Ian S Hitchcock, Dashyant Dhanak, Ricardo Macarron, Isabelle Plo, Horacio G Nastri, Patrick A Mayes
Journal: Blood
Blood blood.2024024373.
https://doi.org/10.1182/blood.2024024373
Published: 2024
Includes: Supplemental data
Journal Articles

Preclinical Evaluation of INCB160058 - a Novel and Potentially Disease-Modifying Therapy for JAK2V617F Mutant Myeloproliferative Neoplasms

Matthew C. Stubbs, Hamza Celik, Yanran Ai, Xin He, Hong Chang, Angela Lei, Mark Rupar, Brittney Wass, Melody Diamond, Xiaoming Wen, Jun Li, Nina Zolotarjova, Alex Margulis, Gaurang Trivedi, Angelo B.A. Laranjeira, Cooper A. Taylor, Jennifer Rocha, Christoph Pollmann, Jacob Piehler, Bianca L. Ferreira, Ian Hitchcock, Ricardo Macarrón, Eddy W. Yue, Sunkyu Kim
Journal: Blood
Blood (2023) 142 (Supplement 1): 860.
https://doi.org/10.1182/blood-2023-179369
Published: 2023
Journal Articles

Discovery of INCA033989, a Monoclonal Antibody That Selectively Antagonizes Mutant Calreticulin Oncogenic Function in Myeloproliferative Neoplasms (MPNs)

Edimara Reis, Rebecca Buonpane, Hamza Celik, Caroline Marty, Angela Lei, Fatoumata Jobe, Mark Rupar, Yue Zhang, Darlise DiMatteo, Rahel Awdew, William Vainchenker, Jing Zhou, Ian Hitchcock, Isabelle Plo, Horacio Nastri, Patrick Mayes
Journal: Blood
Blood (2022) 140 (Supplement 1): 14–15.
https://doi.org/10.1182/blood-2022-159435
Published: 2022