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Journal Articles

Clonal landscape and clinical outcomes of telomere biology disorders: somatic rescuing and cancer mutations

Blood blood.2024025023.

https://doi.org/10.1182/blood.2024025023

Published: 2024

Includes: Supplemental data

Journal Articles

T-cell dysfunctions in myelodysplastic syndromes

Juan Jose Rodriguez-Sevilla, Simona Colla

Blood (2024) 143 (14): 1329–1343.

https://doi.org/10.1182/blood.2023023166

Published: 2024

Includes: Supplemental data

Journal Articles

A road map of relapse in MDS after allo-HSCT

Juan Jose Rodriguez-Sevilla, Simona Colla

Blood (2024) 143 (11): 941–943.

https://doi.org/10.1182/blood.2023023533

Published: 2024

Journal Articles

Mutant Natural Killer Cell Dysfunction Enables the Immune Escape of Premalignant MDS Cell Clones

Blood (2023) 142 (Supplement 1): 514.

https://doi.org/10.1182/blood-2023-184349

Published: 2023

Journal Articles

Oral Decitabine/Cedazuridine with Venetoclax in High-Risk Myelodysplastic Syndrome or Chronic Myelomonocytic Leukemia: Analysis By Different Response Criteria

Blood (2023) 142 (Supplement 1): 3228.

https://doi.org/10.1182/blood-2023-189203

Published: 2023

Journal Articles

Blood Count Recovery and Telomere Elongation in a TINF2 Patient Under Treatment with a Gonadotropin-Releasing Hormone (GnRH) Agonist

Fernanda Gutierrez-Rodrigues, Natthakan Thongon, Christopher L Williams, Simona Colla, Neal S. Young, Alison A. Bertuch

Blood (2023) 142 (Supplement 1): 2735.

https://doi.org/10.1182/blood-2023-190210

Published: 2023

Journal Articles

Myelodysplastic Syndrome Hematopoietic Stem Cells Can Undergo Differentiation Trajectory Rewiring to Escape Venetoclax Vulnerability

Juan Jose Rodriguez Sevilla, Irene Ganan-Gomez, Feiyang Ma, Kelly S. Chien, Guillermo Montalban-Bravo, Rashmi Kanagal-Shamanna, Sanam Loghavi, Vera Adema, Natthakan Thongon, Alexandre Bazinet, Guillermo Garcia-Manero, Simona Colla

Blood (2023) 142 (Supplement 1): 584.

https://doi.org/10.1182/blood-2023-180447

Published: 2023

Journal Articles

STAT3 Protects Hematopoietic Stem and Progenitor Cell Function in Non-Inflamed Conditions

Bhakti Patel, Yifan Zhou, Rachel L Babcock, Feiyang Ma, Yusra B Medik, Laura M Kahn, Josue E Pineda, Elizabeth Park, Karen Clise-Dwyer, Simona Colla, Stephanie S Watowich

Blood (2022) 140 (Supplement 1): 2864–2865.

https://doi.org/10.1182/blood-2022-170250

Published: 2022

Journal Articles

Genomic Evolution of Patients with Myelodysplastic Syndrome after Hypomethylating Agent Failure

Blood (2022) 140 (Supplement 1): 9773–9775.

https://doi.org/10.1182/blood-2022-169213

Published: 2022

Journal Articles

Dual BCL-XL/2 Protac 753B Not Only Potently Induces Apoptosis in Venetoclax-Resistant Primary AML Cells but Also Effectively Eliminates Chemotherapy-Induced Senescent AML Cells

Yannan Jia, Lina Han, Cassandra L Ramage, Connie C. Weng, Lei Yang, Simona Colla, Helen Ma, Weiguo Zhang, Michael Andreeff, Naval Daver, Nitin Jain, Naveen Pemmaraju, Kapil N. Bhalla, Satu Mustjoki, Peiyi Zhang, Guangrong Zheng, Daohong Zhou, Qi Zhang, Marina Konopleva

Blood (2022) 140 (Supplement 1): 3347–3349.

https://doi.org/10.1182/blood-2022-164541

Published: 2022

Journal Articles

Clinical and Biological Effects of Canakinumab in Lower-Risk Myelodysplastic Syndromes (MDS): Results from a Phase 2 Clinical Trial

Guillermo Garcia-Manero, Vera Adema, Samuel Urrutia, Feiyang Ma, Hui Yang, Irene Ganan-Gomez, Gautam Borthakur, Koichi Takahashi, Nicholas Short, Ghayas C. Issa, Kelly S. Chien, Guillermo Montalban-Bravo, Joby Joseph, Simona Colla

Blood (2022) 140 (Supplement 1): 2078–2080.

https://doi.org/10.1182/blood-2022-167703

Published: 2022

Journal Articles

Cancer Chemotherapy Accelerates the Loss of Clonal Diversity in Hematopoietic Stem Cells and Promotes the Convergent Evolution of Therapy-Related Clonal Hematopoiesis

Blood (2022) 140 (Supplement 1): 2232–2233.

https://doi.org/10.1182/blood-2022-160294

Published: 2022

Journal Articles

Orthogonal Proteogenomic Approaches Identify the Druggable PA2G4-MYC Axis in 3q26 AML

Matteo Marchesini, Andrea Gherli, Elisa Simoncini, Anna Montanaro, Natthakan Thongon, Luca Pagliaro, Federica Vento, Lucas Moron Dalla Tor, Chiara Liverani, Raffaella Zamponi, Elena Follini, Benedetta Cambò, Bruno Lorusso, Roberta La Starza, Antonio Cuneo, Cristina Mecucci, Simona Colla, Federico Quaini, Giovanni Roti

Blood (2022) 140 (Supplement 1): 673–674.

https://doi.org/10.1182/blood-2022-158990

Published: 2022

Journal Articles

Single-Cell RNA Sequencing Analysis Reveals Mechanisms of Initiation and Progression in Chronic Myelomonocytic Leukemia

Guillermo Montalban-Bravo, Feiyang Ma, Irene Ganan-Gomez, Rashmi Kanagal-Shamanna, Vera Adema, Yue Wei, Kelly S. Chien, Natthakan Thongon, Hui Yang, Carlos E. Bueso-Ramos, Hagop Kantarjian, Guillermo Garcia-Manero, Simona Colla

Blood (2021) 138 (Supplement 1): 2588.

https://doi.org/10.1182/blood-2021-151340

Published: 2021

Journal Articles

The Transcriptional and Epigenetic Reprogramming of Aged Hematopoietic Stem Cells Drives Myeloid Rewiring in Clonal Hematopoiesis-Associated Cytopenias

Irene Ganan-Gomez, Kelly S. Chien, Feiyang Ma, Hui Yang, Lin Tan, Philip Lorenzi, Guillermo Garcia-Manero, Simona Colla

Blood (2021) 138 (Supplement 1): 3273.

https://doi.org/10.1182/blood-2021-150663

Published: 2021

Journal Articles

U2AF1 and Other Splicing Factor Gene Mutations in Telomere Biology Disorders Are Associated with Hematologic Neoplasia and Worse Overall Survival

Emma M. Groarke, Fernanda Gutierrez-Rodrigues, Xiaoyang Ma, Bhavisha A. Patel, Nina Spitofsky, Paul V. Browne, Kelly S. Chien, Colin O. Wu, Courtney D. DiNardo, Simona Colla, Rodrigo T. Calado, Neal S. Young

Blood (2021) 138 (Supplement 1): 862.

https://doi.org/10.1182/blood-2021-146946

Published: 2021

Journal Articles

Inhibition of MDM2 Improves the Therapeutic Effect of Hypomethylating Agents in Myelodysplastic Syndromes (MDS) and Chronic Myelomonocytic Leukemia (CMML)

Yue Wei, Hong Zheng, Pamela Lockyer, Naran Bao, Faezeh Darbaniyan, Ziyi Li, Rashmi Kanagal-Shamanna, Kelly A. Soltysiak, Hui Yang, Irene Ganan-Gomez, Kim-Anh Do, Simona Colla, Kelly S. Chien, Guillermo Montalban-Bravo, Naval Daver, Guillermo Garcia-Manero

Blood (2021) 138 (Supplement 1): 3664.

https://doi.org/10.1182/blood-2021-150811

Published: 2021

Journal Articles

Clonal Hematopoiesis in Telomere Biology Disorders Associates with the Underlying Germline Defect and Somatic Mutations in POT1 , PPM1D, and TERT promoter

Fernanda Gutierrez-Rodrigues, Emma M Groarke, Diego V Clé, Bhavisha A. Patel, Flávia S Donaires, Nina Spitofsky, Lemlem Alemu, Bárbara A Santana, Sachiko Kajigaya, Simona Colla, Michel Michels De Oliveira, Carmem M. S. Bonfim, Rodrigo T. Calado, Neal S. Young

Blood (2021) 138 (Supplement 1): 1111.

https://doi.org/10.1182/blood-2021-151199

Published: 2021

Journal Articles

Targeting DNA2 Overcomes Myeloma Cells' Metabolic Reprogramming in Response to DNA Damage

Natthakan Thongon, Andrea Santoni, Jintan Liu, Natalia Baran, Feiyang Ma, Christopher Jackson, Pamela Lockyer, Irene Ganan-Gomez, Vera Adema, Ashley Rose, Matteo Marchesini, Yun Qing, Min Jin Ha, Caleb Class, Matteo Pellegrini, Lin Tan, Philip Lorenzi, Marina Konopleva, Simona Colla

Blood (2021) 138 (Supplement 1): 1573.

https://doi.org/10.1182/blood-2021-148992

Published: 2021

Journal Articles

Transcriptomic Signitures of Azacitidine (AZA) and Decitabine (DAC) Resistance in MDS and CMML

Faezeh Darbaniyan, Caleb Class, Guillermo Montalban-Bravo, Rashmi Kanagal-Shamanna, Marcos Estecio, Yue Lu, Kelly A. Soltysiak, Kelly S. Chien, Hui Yang, Koji Sasaki, Irene Ganan-Gomez, Simona Colla, Kim-Anh Do, Guillermo Garcia-Manero, Yue Wei

Blood (2021) 138 (Supplement 1): 4652.

https://doi.org/10.1182/blood-2021-153698

Published: 2021

NARROW

Clonal landscape and clinical outcomes of telomere biology disorders: somatic rescuing and cancer mutations

T-cell dysfunctions in myelodysplastic syndromes

A road map of relapse in MDS after allo-HSCT

Mutant Natural Killer Cell Dysfunction Enables the Immune Escape of Premalignant MDS Cell Clones

Oral Decitabine/Cedazuridine with Venetoclax in High-Risk Myelodysplastic Syndrome or Chronic Myelomonocytic Leukemia: Analysis By Different Response Criteria

Blood Count Recovery and Telomere Elongation in a TINF2 Patient Under Treatment with a Gonadotropin-Releasing Hormone (GnRH) Agonist

Myelodysplastic Syndrome Hematopoietic Stem Cells Can Undergo Differentiation Trajectory Rewiring to Escape Venetoclax Vulnerability

STAT3 Protects Hematopoietic Stem and Progenitor Cell Function in Non-Inflamed Conditions

Genomic Evolution of Patients with Myelodysplastic Syndrome after Hypomethylating Agent Failure

Dual BCL-XL/2 Protac 753B Not Only Potently Induces Apoptosis in Venetoclax-Resistant Primary AML Cells but Also Effectively Eliminates Chemotherapy-Induced Senescent AML Cells

Clinical and Biological Effects of Canakinumab in Lower-Risk Myelodysplastic Syndromes (MDS): Results from a Phase 2 Clinical Trial

Cancer Chemotherapy Accelerates the Loss of Clonal Diversity in Hematopoietic Stem Cells and Promotes the Convergent Evolution of Therapy-Related Clonal Hematopoiesis

Orthogonal Proteogenomic Approaches Identify the Druggable PA2G4-MYC Axis in 3q26 AML

Single-Cell RNA Sequencing Analysis Reveals Mechanisms of Initiation and Progression in Chronic Myelomonocytic Leukemia

The Transcriptional and Epigenetic Reprogramming of Aged Hematopoietic Stem Cells Drives Myeloid Rewiring in Clonal Hematopoiesis-Associated Cytopenias

U2AF1 and Other Splicing Factor Gene Mutations in Telomere Biology Disorders Are Associated with Hematologic Neoplasia and Worse Overall Survival

Inhibition of MDM2 Improves the Therapeutic Effect of Hypomethylating Agents in Myelodysplastic Syndromes (MDS) and Chronic Myelomonocytic Leukemia (CMML)

Clonal Hematopoiesis in Telomere Biology Disorders Associates with the Underlying Germline Defect and Somatic Mutations in POT1 , PPM1D, and TERT promoter

Targeting DNA2 Overcomes Myeloma Cells' Metabolic Reprogramming in Response to DNA Damage

Transcriptomic Signitures of Azacitidine (AZA) and Decitabine (DAC) Resistance in MDS and CMML

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American Society of Hematology

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ASH Publications

American Society of Hematology

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