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Journal Articles

Infection risk factors and burden in patients treated with T-cell engaging bispecific antibodies for relapsed B-cell lymphoma and multiple myeloma

Blood (2025) 146 (Supplement 1): 2814.

https://doi.org/10.1182/blood-2025-2814

Published: 2025

Journal Articles

Ferroptosis activates NK and CAR T cell-mediated anti-tumor immunity in Acute Myeloid Leukemia

Saurabh Kumar Gupta, Kazuharu Kamachi, Liang Zhang, Ran Zhao, Babita Kaundal, Jiangxing LV, Li Li, Venkata Lokesh Battula, Xufeng Chen, Hussein Abbas, Michael Andreeff, Jo Ishizawa

Blood (2025) 146 (Supplement 1): 1496.

https://doi.org/10.1182/blood-2025-1496

Published: 2025

Journal Articles

A genome-wide CRISPR screen identifies conventional and novel ferroptosis regulators in Acute Myeloid Leukemia

Liang Zhang, Ran Zhao, Kazuharu Kamachi, Saurabh Kumar Gupta, Hiroki Akiyama, Michael Andreeff, Jo Ishizawa

Blood (2025) 146 (Supplement 1): 5057.

https://doi.org/10.1182/blood-2025-5057

Published: 2025

Journal Articles

Unidirectional synergy between ferroptosis and apoptosis reveals a novel therapeutic strategy for refractory AML

Blood (2025) 146 (Supplement 1): 5050.

https://doi.org/10.1182/blood-2025-5050

Published: 2025

Journal Articles

Modeling discordant cardiac and renal recovery trajectories in AL amyloidosis using interpretable machine learning

John Hanna, Ran Zhao, Diana Basali, Shahzad Raza, Jack Khouri, Sandra Mazzoni, Christy Samaras, Beth Faiman, Ali Mehdi, Mazen Hanna, Faiz Anwer, Jason Valent, Louis Williams

Blood (2025) 146 (Supplement 1): 5743.

https://doi.org/10.1182/blood-2025-5743

Published: 2025

Journal Articles

Severe neutropenia after treatment with T-cell engaging bispecific antibodies is associated with higher rates of CRS and disease response

Blood (2025) 146 (Supplement 1): 6350.

https://doi.org/10.1182/blood-2025-6350

Published: 2025

Journal Articles

Selinexor enhances the effect of venetoclax on Acute Myeloid Leukemia stem and progenitor cells by disrupting lysosomal function

Ran Zhao, Hongwei Peng, Jiaqi Wan, Yulan Zhou, Fancong Kong, Fei Li

Blood (2025) 146 (Supplement 1): 3290.

https://doi.org/10.1182/blood-2025-3290

Published: 2025

Journal Articles

Isolation of Lipid Droplets from Acute Myeloid Leukemia Cells for Lipidomic Analysis

Ran Zhao, Liang Zhang, Kazuharu Kamachi, Saurabh Kumar Gupta, Hiroki Akiyama, Jalen Nguyen, Michael Andreeff, Jo Ishizawa, Alessia Lodi

Blood (2024) 144 (Supplement 1): 7502.

https://doi.org/10.1182/blood-2024-201676

Published: 2024

Journal Articles

Molecular Interactions between Mitochondrial Ferroptosis and Apoptosis Pathways in Acute Myeloid Leukemia

Kazuharu Kamachi, Hiroki Akiyama, Ran Zhao, Liang Zhang, Saurabh Kumar Gupta, Lauren B. Ostermann, Yuji Otsuki, Osamu Nagano, Hideyuki Saya, Ayumu Taguchi, Michael Andreeff, Jo Ishizawa

Blood (2024) 144 (Supplement 1): 2765.

https://doi.org/10.1182/blood-2024-201661

Published: 2024

Journal Articles

Targeting Lipid Droplet Biogenesis to Enhance Ferroptosis in Acute Myeloid Leukemia

Liang Zhang, Ran Zhao, Hiroki Akiyama, Jalen Nguyen, Kazuharu Kamachi, Saurabh Kumar Gupta, Valeria Impedovo, G. Lavender Hackman, Michael Andreeff, Alessia Lodi, Jo Ishizawa

Blood (2024) 144 (Supplement 1): 1400.

https://doi.org/10.1182/blood-2024-208616

Published: 2024

Journal Articles

Novel p53 Mutant Mouse Model Recapitulates the Biology of Human Therapy-Related Myeloid Neoplasms

Rasoul Pourebrahim, Dexin Yang, Priyanka Khanna, Muharrem Muftuoglu, Lauren B. Ostermann, Shayaun Khazaei, Ran Zhao, Mihai Gagea, Simona Colla, Guillermo Garcia-Manero, Ruoyan Li, Michael Andreeff, Koichi Takahashi

Blood (2024) 144 (Supplement 1): 882.

https://doi.org/10.1182/blood-2024-207582

Published: 2024

Journal Articles

Mitigating Therapy-Related Myeloid Neoplasia in p53-Mutant Clones through Targeted DNA Repair Pathway Inhibition with PARP Inhibitors

Rasoul Pourebrahim, Priyanka Khanna, Dexin Yang, Muharrem Muftuoglu, Lauren B. Ostermann, Shayaun Khazaei, Ran Zhao, Amma Asare, Richard A. Hajek, Sanghoon Lee, Sara Corvingo, Mihai Gagea, Anil Sood, Ruoyan Li, Koichi Takahashi, Michael Andreeff

Blood (2024) 144 (Supplement 1): 726.

https://doi.org/10.1182/blood-2024-208373

Published: 2024

Journal Articles

Calibrated Release IL15 Bivalent CD33 and/or FLT3 and NOT Emcn Logic Gated Gene Circuit CAR-NK Cell Therapy (SENTI-202) in Venetoclax Resistant Patient Derived Xenograft Acute Myeloid Leukemia Models

Muharrem Muftuoglu, Mahesh Basyal, Li Li, Jiangxing Lv, Lauren B. Ostermann, Ran Zhao, Baozhen Ke, Hiroki Akiyama, Po Yee Mak, Bing Z. Carter, Han Deng, Yongshuai Li, Brian S. Garrison, Kanya L. Rajangam, Michael Andreeff

Blood (2023) 142 (Supplement 1): 4831.

https://doi.org/10.1182/blood-2023-191127

Published: 2023

Journal Articles

Race and Gender Representation in Myelodysplastic Syndrome Clinical Trials in the US: A Cohort Study

Sindhusha Veeraballi, Ran Zhao, Megha Sai Konka, Hetty E. Carraway, Moaath K. Mustafa Ali, Aaron T. Gerds, Arooj Ahmed, Anjali S. Advani, John C Molina, Sophia Balderman, Abhay Singh, Sudipto Mukherjee

Blood (2023) 142 (Supplement 1): 1855.

https://doi.org/10.1182/blood-2023-189959

Published: 2023

Journal Articles

Mitophagy As a Novel Cell-Protective Mechanism Against Mitochondrial Ferroptosis in Acute Myeloid Leukemia

Hiroki Akiyama, Matthew Tcheng, Priyanka Sharma, Ran Zhao, Lauren B. Ostermann, Samar Yazdani, Arman Moayed, Zdzislaw Szulc, Natalia Oleinik, Po Yee Mak, Vivian Ruvolo, Bing Z. Carter, Besim Ogretmen, Gautam Borthakur, Aaron D. Schimmer, Michael Andreeff, Jo Ishizawa

Blood (2023) 142 (Supplement 1): 2804.

https://doi.org/10.1182/blood-2023-181410

Published: 2023

Journal Articles

Age-Specific Induction of Mutant p53 Drives Clonal Hematopoiesis in Adult Mice Leading to Acute Myeloid Leukemia

Rasoul Pourebrahim, Shayaun Khazaei, Lauren B. Ostermann, Ran Zhao, Muharrem Muftuoglu, Michael Andreeff

Blood (2023) 142 (Supplement 1): 1382.

https://doi.org/10.1182/blood-2023-186454

Published: 2023

Journal Articles

Mitochondrial Regulation of Ferroptosis in Acute Myeloid Leukemia

Hiroki Akiyama, Ran Zhao, Yuki Nishida, Natalia Baran, Ziyi Li, Lauren B Ostermann, Po Yee Mak, Edward Ayoub, Sujan Piya, Bing Z Carter, Michael Andreeff, Jo Ishizawa

Blood (2022) 140 (Supplement 1): 8785–8786.

https://doi.org/10.1182/blood-2022-162354

Published: 2022

Journal Articles

Assessment of Major Adverse Cardiac Events (MACE) and Arrhythmias in Patients with Large B-Cell Lymphoma Undergoing Anti-CD19 Chimeric Antigen Receptor T-Cell (CAR-T) Therapy: Impact of Baseline Cardiac Biomarkers

Haikoo Shah, Danielle O'Conke, Ran Zhao, Akansha Jalota, Manishkumar S. Patel, Allison Winter, Louis S. Williams, Jack Khouri, Deepa Jagadeesh, Faiz Anwer, Robert M. Dean, Betty K. Hamilton, Ronald M. Sobecks, Brad Pohlman, Paolo F. Caimi, Craig S. Sauter, Neetu Gupta, Brian T. Hill

Blood (2022) 140 (Supplement 1): 4673–4675.

https://doi.org/10.1182/blood-2022-169412

Published: 2022

Journal Articles

Therapeutic Targeting of Ferroptosis Pathway in Combination with Mitochondrial Oxidative Stress Induction in Acute Myeloid Leukemia

Hiroki Akiyama, Ran Zhao, Adam Rahhal, Yuki Nishida, Edward Ayoub, Lauren B Ostermann, Michael Andreeff, Jo Ishizawa

Blood (2021) 138 (Supplement 1): 1162.

https://doi.org/10.1182/blood-2021-148248

Published: 2021

Journal Articles

Genomic Data Improves Prognostic Stratification in Adult T-Cell Acute Lymphoblastic Leukemia Patients Enrolled in Measurable Residual Disease-Oriented Trials

Blood (2021) 138 (Supplement 1): 3486.

https://doi.org/10.1182/blood-2021-148263

Published: 2021

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Infection risk factors and burden in patients treated with T-cell engaging bispecific antibodies for relapsed B-cell lymphoma and multiple myeloma

Ferroptosis activates NK and CAR T cell-mediated anti-tumor immunity in Acute Myeloid Leukemia

A genome-wide CRISPR screen identifies conventional and novel ferroptosis regulators in Acute Myeloid Leukemia

Unidirectional synergy between ferroptosis and apoptosis reveals a novel therapeutic strategy for refractory AML

Modeling discordant cardiac and renal recovery trajectories in AL amyloidosis using interpretable machine learning

Severe neutropenia after treatment with T-cell engaging bispecific antibodies is associated with higher rates of CRS and disease response

Selinexor enhances the effect of venetoclax on Acute Myeloid Leukemia stem and progenitor cells by disrupting lysosomal function

Isolation of Lipid Droplets from Acute Myeloid Leukemia Cells for Lipidomic Analysis

Molecular Interactions between Mitochondrial Ferroptosis and Apoptosis Pathways in Acute Myeloid Leukemia

Targeting Lipid Droplet Biogenesis to Enhance Ferroptosis in Acute Myeloid Leukemia

Novel p53 Mutant Mouse Model Recapitulates the Biology of Human Therapy-Related Myeloid Neoplasms

Mitigating Therapy-Related Myeloid Neoplasia in p53-Mutant Clones through Targeted DNA Repair Pathway Inhibition with PARP Inhibitors

Calibrated Release IL15 Bivalent CD33 and/or FLT3 and NOT Emcn Logic Gated Gene Circuit CAR-NK Cell Therapy (SENTI-202) in Venetoclax Resistant Patient Derived Xenograft Acute Myeloid Leukemia Models

Race and Gender Representation in Myelodysplastic Syndrome Clinical Trials in the US: A Cohort Study

Mitophagy As a Novel Cell-Protective Mechanism Against Mitochondrial Ferroptosis in Acute Myeloid Leukemia

Age-Specific Induction of Mutant p53 Drives Clonal Hematopoiesis in Adult Mice Leading to Acute Myeloid Leukemia

Mitochondrial Regulation of Ferroptosis in Acute Myeloid Leukemia

Assessment of Major Adverse Cardiac Events (MACE) and Arrhythmias in Patients with Large B-Cell Lymphoma Undergoing Anti-CD19 Chimeric Antigen Receptor T-Cell (CAR-T) Therapy: Impact of Baseline Cardiac Biomarkers

Therapeutic Targeting of Ferroptosis Pathway in Combination with Mitochondrial Oxidative Stress Induction in Acute Myeloid Leukemia

Genomic Data Improves Prognostic Stratification in Adult T-Cell Acute Lymphoblastic Leukemia Patients Enrolled in Measurable Residual Disease-Oriented Trials

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