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Journal Articles

Risk prediction for clonal cytopenia: multicenter real-world evidence

Clinical Trials & Observations
Zhuoer Xie, Rami Komrokji, Najla Al Ali, Alexandra Regelson, Susan Geyer, Anand Patel, Caner Saygin, Amer M. Zeidan, Jan Philipp Bewersdorf, Lourdes Mendez, Ashwin Kishtagari, Joshua F. Zeidner, Catherine C. Coombs, Yazan F. Madanat, Stephen Chung, Talha Badar, James Foran, Pinkal Desai, Charlton Tsai, Elizabeth A. Griffiths, Monzr M. Al Malki, Idoroenyi Amanam, Catherine Lai, H. Joachim Deeg, Lionel Ades, Cecilia Arana Yi, Afaf E. G. Osman, Shira Dinner, Yasmin Abaza, Justin Taylor, Namrata Chandhok, Deborah Soong, Andrew M. Brunner, Hetty E. Carraway, Abhay Singh, Chiara Elena, Jacqueline Ferrari, Anna Gallì, Sara Pozzi, Eric Padron, Mrinal M. Patnaik, Luca Malcovati, Michael R. Savona, Aref Al-Kali
Journal: Blood
Blood (2024) 144 (19): 2033–2044.
https://doi.org/10.1182/blood.2024024756
Published: 2024
Includes: Supplemental data
Journal Articles

Evaluation of the Molecular International Prognostic Scoring System (IPSS-M) in Patients (Pts) with Myelodysplastic Syndromes/Neoplasms (MDS) with Missing Molecular Data

Tariq Kewan, Jan Philipp Bewersdorf, Ondrej Blaha, Maximilian Stahl, Najla H Al Ali, Amy E. DeZern, Mikkael A. Sekeres, Hetty E. Carraway, Pinkal Desai, Elizabeth A. Griffiths, Eytan M. Stein, Andrew M. Brunner, Maria L Amaya, Joshua F. Zeidner, Michael R. Savona, Jessica M. Stempel, Namrata Sonia Chandhok, Constantine Logothetis, Hunter Cochran, Abhay Singh, Gail J. Roboz, Benjamin Rolles, Eunice S. Wang, Amyah C. Harris, Rory M. Shallis, Zhuoer Xie, Eric Padron, David A Sallman, Jaroslaw P. Maciejewski, Matteo Giovanni Della Porta, Rami S. Komrokji, Amer M. Zeidan
Journal: Blood
Blood (2023) 142 (Supplement 1): 4607.
https://doi.org/10.1182/blood-2023-187053
Published: 2023
Journal Articles

Race and Gender Representation in Myelodysplastic Syndrome Clinical Trials in the US: A Cohort Study

Sindhusha Veeraballi, Ran Zhao, Megha Sai Konka, Hetty E. Carraway, Moaath K. Mustafa Ali, Aaron T. Gerds, Arooj Ahmed, Anjali S. Advani, John C Molina, Sophia Balderman, Abhay Singh, Sudipto Mukherjee
Journal: Blood
Blood (2023) 142 (Supplement 1): 1855.
https://doi.org/10.1182/blood-2023-189959
Published: 2023
Journal Articles

Significance of the Apoptotic Regulators BAX, BCL2, BCL- XL and MCL1 in Newly Diagnosed AML

Sarah J Philip, Valeria Visconte, Hetty E. Carraway, Aaron T. Gerds, Abhay Singh, Sophia Balderman, John C Molina, Moaath K. Mustafa-Ali, Sudipto Mukherjee, Jaroslaw P. Maciejewski, Anjali S. Advani
Journal: Blood
Blood (2023) 142 (Supplement 1): 5995.
https://doi.org/10.1182/blood-2023-185081
Published: 2023
Journal Articles

Can Emergency Hematopoiesis Due to Sepsis Lead to Clonal Hematopoiesis? Implications for Understanding the Pathogenesis of Clonal Evolution

Olisaemeka Ogbue, Tariq Kewan, Omar Mehkri, Francois Fadell, Ishani Nautiyal, Megan Reynold, Arda Durmaz, Jennifer VanOudenhove, Hussein Awada, Serhan Unlu, Abhay Singh, Valeria Visconte, Lourdes Mendez, David S. Bosler, Abhijit Duggal, Stephanie Halene, Jaroslaw P. Maciejewski, Mohammed J Al-Jaghbeer, Carmelo Gurnari
Journal: Blood
Blood (2023) 142 (Supplement 1): 2691.
https://doi.org/10.1182/blood-2023-187424
Published: 2023
Journal Articles

Risk of Myelodysplastic Syndromes (MDS) in Adolescents and Young Adults with Cancers Treated with Chemotherapy with or without Radiotherapy

Rahul Mishra, Xuefei Jia, Debolina Pramanik, Abhay Singh, Sindhusha Veeraballi, Sophia Balderman, John C Molina, Anjali S. Advani, Moaath K. Mustafa-Ali, Hetty E. Carraway, Aaron T. Gerds, Nargiz F Muganlinskaya, Sudipto Mukherjee
Journal: Blood
Blood (2023) 142 (Supplement 1): 2351.
https://doi.org/10.1182/blood-2023-190692
Published: 2023
Journal Articles

A Phase 2 Study of Fedratinib in Patients with MDS/MPN and Chronic Neutrophilic Leukemia

Andrew T. Kuykendall, Kristen Marie Pettit, Abhay Singh, Tania Jain, David A Sallman, Qianxing Mo, Quan Lovette, Ling Zhang, Onyee Chan, Alison R. Walker, Zhuoer Xie, Jeffrey Lancet, Maria Balasis, Seongseok Yun, Eric Padron, Rami S. Komrokji
Journal: Blood
Blood (2023) 142 (Supplement 1): 73.
https://doi.org/10.1182/blood-2023-182879
Published: 2023
Journal Articles

Risk of Therapy-Related Acute Myeloid Leukemia (t-AML) in Adolescent and Young Adults Cancer Patients Treated with Chemotherapy with or without Radiotherapy: A National Population-Based Cohort Study Using SEER Registry

Rahul Mishra, Abhay Singh, Sindhusha Veeraballi, Sophia Balderman, John C Molina, Anjali S. Advani, Moaath K. Mustafa-Ali, Hetty E. Carraway, Aaron T. Gerds, Nargiz F Muganlinskaya, Sudipto Mukherjee
Journal: Blood
Blood (2023) 142 (Supplement 1): 377.
https://doi.org/10.1182/blood-2023-190353
Published: 2023
Journal Articles

Clinical Implications of TP53 Mutations/Allelic State in Patients (Pts) with Myelodysplastic Syndromes/Neoplasms (MDS) Treated with Hypomethylating Agents (HMA)- a Multicenter, Retrospective Analysis from the Validate Database

Tariq Kewan, Jan Philipp Bewersdorf, Ondrej Blaha, Maximilian Stahl, Najla H Al Ali, Amy E. DeZern, Mikkael A. Sekeres, Hetty E. Carraway, Pinkal Desai, Elizabeth A. Griffiths, Eytan M. Stein, Andrew M. Brunner, Maria L Amaya, Joshua F. Zeidner, Michael R. Savona, Jessica M. Stempel, Namrata Sonia Chandhok, Hunter Cochran, Rahul Ramaswamy, Abhay Singh, Gail J. Roboz, Benjamin Rolles, Eunice S. Wang, Amyah C. Harris, Rory M. Shallis, Zhuoer Xie, Eric Padron, Jaroslaw P. Maciejewski, Matteo Giovanni Della Porta, Rami S. Komrokji, David A Sallman, Amer M. Zeidan
Journal: Blood
Blood (2023) 142 (Supplement 1): 1002.
https://doi.org/10.1182/blood-2023-186875
Published: 2023
Journal Articles

The Epidemiology of Cardiovascular Disease in African American Patients with Myeloid Neoplasms: A SEER Data Analysis

Sindhusha Veeraballi, Yanwen Chen, Hetty E. Carraway, Aaron T. Gerds, Moaath K. Mustafa Ali, Arooj Ahmed, Anjali S. Advani, John C Molina, Sophia Balderman, Jaroslaw P. Maciejewski, Sudipto Mukherjee, Abhay Singh
Journal: Blood
Blood (2023) 142 (Supplement 1): 5181.
https://doi.org/10.1182/blood-2023-189294
Published: 2023
Journal Articles

ANKRD26 Coding Variants in Myeloid Neoplasia

Teodora Kuzmanovic, Metis Hasipek, Samuel Li, Thomas Laframboise, Valeria Visconte, Sunisa Kongkiatkamon, Seth J. Corey, Sudipto Mukherjee, Anjali Advani, Aaron T. Gerds, Yogenthiran Saunthararajah, Sophia R. Balderman, Abhay Singh Singh, Hetty E. Carraway, Niroshan Nadarajah, Manja Meggendorfer, Jaroslaw P. Maciejewski, Bhumika J. Patel
Journal: Blood
Blood (2022) 140 (Supplement 1): 4013–4015.
https://doi.org/10.1182/blood-2022-170645
Published: 2022
Journal Articles

Validation of the Molecular International Prognostic Scoring System in Patients with Myelodysplastic Syndrome

Tariq Kewan, Waled Bahaj, Mai Aly, Arda Durmaz, Olisaemeka Ogbue, Hetty E. Carraway, Abhay Singh Singh, Suresh Kumar Balasubramanian, Mikkael A. Sekeres, Valeria Visconte, Carmelo Gurnari, Jaroslaw P. Maciejewski
Journal: Blood
Blood (2022) 140 (Supplement 1): 6942–6944.
https://doi.org/10.1182/blood-2022-163845
Published: 2022
Journal Articles

Risk of Therapy-Related Acute Myeloid Leukemia (t-AML) in Cancer Patients Treated with Chemotherapy with or without Radiotherapy: A National Population-Based Cohort Study Using SEER Registry

Julia H. Joo, Yanwen Chen, Aaron T. Gerds, Anjali Advani, Sophia R. Balderman, Hetty E. Carraway, Abhay Singh Singh, Sudipto Mukherjee
Journal: Blood
Blood (2022) 140 (Supplement 1): 687–689.
https://doi.org/10.1182/blood-2022-163565
Published: 2022
Journal Articles

Molecular and Clinical Spectra of Protein Phosphatase, Mg2+/Mn2+-Dependent 1D ( PPM1D )-Mutant Myeloid Neoplasms

Mai M M Aly, Valeria Visconte, Carmelo Gurnari, Reem Alagooz, Arda Durmaz, Suresh Kumar Balasubramanian, Abhay Singh Singh, Bhumika J. Patel, Tariq Kewan, Waled Bahaj, Jaroslaw P. Maciejewski
Journal: Blood
Blood (2022) 140 (Supplement 1): 12298–12300.
https://doi.org/10.1182/blood-2022-160332
Published: 2022
Journal Articles

Risk Factors Beyond Chemo-Radiotherapy Exposure for Therapy-Related Myelodysplastic Syndrome (tMDS) and Acute Myeloid Leukemia (tAML) Development in Breast Cancer Survivors: A 15-Year SEER-Medicare Analysis

Abhay Singh Singh, Megan M. Herr, Theresa E. Hahn, Swapna Thota
Journal: Blood
Blood (2022) 140 (Supplement 1): 934–935.
https://doi.org/10.1182/blood-2022-159973
Published: 2022
Journal Articles

The Characteristics and Prognosis of Patients with Clonal Cytopenias of Undetermined Significance, Including Cancer and Therapy-Related Clonal Cytopenias

Zhuoer Xie, Alexandra Smith, Rami S. Komrokji, Najla Al Ali, Anand Ashwin Patel, Caner Saygin, Amer M. Zeidan, Jan Philipp Bewersdorf, Ashwin Kishtagari, Joshua F. Zeidner, Catherine C. Coombs, Yazan F. Madanat, James M. Foran, Talha Badar, Pinkal Desai, Charlton Tsai, Elizabeth A. Griffiths, Monzr M. Al Malki, Idoroenyi Amanam, Catherine Lai, Joachim Deeg, Lionel Ades, Cecilia Arana Yi, Afaf Osman, Shira Dinner, Yasmin Abaza, Namrata Chandhok, Deborah Soong, Justin Taylor, Andrew M. Brunner, Hetty E. Carraway, Abhay Singh Singh, Susan M. Geyer, Eric Padron, Mrinal M.M. Patnaik, Michael R. Savona, Aref Al-Kali
Journal: Blood
Blood (2022) 140 (Supplement 1): 2887–2890.
https://doi.org/10.1182/blood-2022-162367
Published: 2022
Journal Articles

DNMT3A and TET2 mutant Clonal Hematopoiesis May Drive a Proinflammatory State and Predict Enhanced Response to Immune Checkpoint Inhibitors

Abhay Singh Singh, Nuria Mencia-Trinchant, Elizabeth A. Griffiths, Mahesh Swaminathan, Matthew Gravina, Rutaba Tajammal, Mark G. Faber, Marc S. Ernstoff, LunBiao Yan, Eti Sinha, Megan M. Herr, Duane C Hassane, Monica L. Guzman, Amanda Przespolewski, Eunice S. Wang, Swapna Thota
Journal: Blood
Blood (2021) 138 (Supplement 1): 4295.
https://doi.org/10.1182/blood-2021-150347
Published: 2021
Journal Articles

Characteristics and Clinical Outcome of Patients with Clonal Cytopenias of Undetermined Significance: A Large Retrospective Multi-Center International Study

Zhuoer Xie, Meredith C. Hyun, Rami S. Komrokji, Amer M. Zeidan, Yazan F. Madanat, Joshua F. Zeidner, Catherine C. Coombs, Elizabeth A. Griffiths, Catherine Lai, Ashwin Kishtagari, James M. Foran, Talha Badar, Cecilia Arana Yi, Pinkal Desai, Lionel Ades, Afaf Osman, Justin Taylor, H. Joachim Deeg, Andrew M. Brunner, Hetty E. Carraway, Najla Al Ali, Jan Philipp Bewersdorf, Thomas Prebet, Abhay Singh, Charlton Tsai, Namrata Chandhok, Deborah Soong, Mrinal M. Patnaik, Michael R. Savona, Aref Al-Kali
Journal: Blood
Blood (2021) 138 (Supplement 1): 2158.
https://doi.org/10.1182/blood-2021-146254
Published: 2021
Journal Articles

Clonal Hematopoiesis in Patients with Neuroendocrine Tumors Receiving Peptide Receptor Radionuclide Therapy (PRRT)

Abhay Singh, MBBS,MPH, Matthew Gravina, MD, Rutaba Tajammal, MD, Annmarie Nowak, Renuka Iyer, MD, Mark G. Faber, DO, LunBiao Yan, PhD, Duane C. Hassane, PhD, Monica L. Guzman, PhD, Nuria Mencia-Trinchant, PhD, Eunice S. Wang, MD, Swapna Thota, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 35–36.
https://doi.org/10.1182/blood-2020-141570
Published: 2020
Journal Articles

Population Level Contribution of Clonal Hematopoiesis of Indeterminate Potential to Myeloid Neoplasm Development: Pooled Analysis and Population Attributable Risk Percent Determination from Case-Control and Cohort Studies

Abhay Singh, MBBS,MPH
Journal: Blood
Blood (2020) 136 (Supplement 1): 16–17.
https://doi.org/10.1182/blood-2020-143380
Published: 2020