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Journal Articles

Clinical and Molecular Insights into the Classification Dilemma: Are MDS/AML Cases Distinct from Secondary AML?

Tariq Kewan, Arda Durmaz, Waled Bahaj, Carmelo Gurnari, Olisaemeka Ogbue, Ahmad Kiwan, Hussein Awada, Hetty E. Carraway, Suresh Kumar Balasubramanian, Taha Bat, Yazan F Madanat, Valeria Visconte, Jaroslaw Maciejewski

Blood (2024) 144 (Supplement 1): 850.

https://doi.org/10.1182/blood-2024-207770

Published: 2024

Journal Articles

Genetic Determinants of Hypercoagulability in Complement and Hemostatic Systems Shape the Thrombotic Risk of Paroxysmal Nocturnal Hemoglobinuria

Carlos Bravo-Perez, Carmelo Gurnari, Arda Durmaz, Stephan Hutter, Zachary Brady, Hussein Awada, Aashray Mandala, Luca Guarnera, Matteo D'Addona, Kartik Lakhotiya, Praveena Thiagarajan, Alan Eli Lichtin, Torsten Haferlach, Valeria Visconte, Jaroslaw Maciejewski

Blood (2024) 144 (Supplement 1): 31.

https://doi.org/10.1182/blood-2024-208885

Published: 2024

Journal Articles

First Results of High Throughput Pipeline for Serotypic and TCR Clonotypic Specificities in Aplastic Anemia and Large Granular Lymphocyte Leukemia Uncovering Antigenic Peptides Relevant to Disease Etiology

Kartik Lakhotiya, Carmelo Gurnari, Carlos Bravo-Perez, Aashray Mandala, Matteo D'Addona, Christopher Haddad, Mark Orland, Zachary Brady, Luca Guarnera, Praveena Thiagarajan, Ishani Nautiyal, Simona Pagliuca, Hari Krishnamurthy, Karthik Krishna, Vasanth Jayaraman, Valeria Visconte, Jaroslaw Maciejewski, Arda Durmaz

Blood (2024) 144 (Supplement 1): 35.

https://doi.org/10.1182/blood-2024-210990

Published: 2024

Journal Articles

Prediction of Post-Transplant Relapse of the Myelodysplastic Syndromes Via Evaluation of Stem Cells

Benjamin Kroger, Roni Tamari, Carmelo Gurnari, Julio Alvarenga Thiebaud, Alejandro Marinos Velarde, Yazan F Madanat, Robert H. Collins, Clayton Jackson, Vivian Irizarry Gatell, Valeria Visconte, Jaroslaw Maciejewski, David Sallman, Stephen Chung

Blood (2024) 144 (Supplement 1): 777.

https://doi.org/10.1182/blood-2024-212380

Published: 2024

Journal Articles

Bi-Allelic DDX41 Mutations Exert Stage Specific Effects on Hematopoiesis to Promote Disease

Benjamin Kroger, Yuanyuan Ji, Toby Thomas, Yazan F Madanat, Robert H. Collins, Valeria Visconte, Carmelo Gurnari, Jaroslaw Maciejewski, Stephen Chung

Blood (2024) 144 (Supplement 1): 347.

https://doi.org/10.1182/blood-2024-209425

Published: 2024

Journal Articles

Predictive Modeling of Hematopoietic Stem Cell Transplant Outcomes: Discovering the Role of Immunogenetic Features through Machine Learning Models

Simona Pagliuca, Carmelo Gurnari, Arda Durmaz, Ashwin Kishtagari, Zain Virk, Lukasz P. Gondek, Matthew Guo, Maria Bettinotti, Mark B Juckett, Qing Cao, Suresh Kumar Balasubramanian, Vikram Dhillon, Ben K. Tomlinson, Koen van Besien, Alice Aarnink, Marie Thérèse Rubio, Valeria Visconte, Jaroslaw Maciejewski

Blood (2024) 144 (Supplement 1): 927.

https://doi.org/10.1182/blood-2024-210565

Published: 2024

Journal Articles

Could Somatic Gene Rescue Explain Frequency of Compound Heterozygous and Concurrent Receptor Tyrosine Kinase Mutations in Hematological Diseases?

Serhan Unlu, Christopher Haddad, Tariq Kewan, Olisaemeka Ogbue, Arda Durmaz, Waled Bahaj, Arooj Ahmed, Carlos Bravo-Perez, Luca Guarnera, Hetty E. Carraway, Yasuo Kubota, Carmelo Gurnari, Torsten Haferlach, Valeria Visconte, Jaroslaw Maciejewski

Blood (2024) 144 (Supplement 1): 3199.

https://doi.org/10.1182/blood-2024-205865

Published: 2024

Journal Articles

Clinically Driven Algorithms Identify Patients with Large Granular Lymphocytic Leukemia at Risk of Significant Cytopenia Requiring Treatment

Ahmad Kiwan, Tariq Kewan, Carlos Bravo-Perez, Valeria Visconte, Carmelo Gurnari, Arda Durmaz, Alexa Siddon, Stephanie Halene, Tarsheen Sethi, Jaroslaw Maciejewski, Francine M. Foss

Blood (2024) 144 (Supplement 1): 4436.

https://doi.org/10.1182/blood-2024-209344

Published: 2024

Journal Articles

Genetic and Molecular Dynamics of DDX41- variants: Insights on the Variant Effect Prediction

Valeria Visconte, Carlos Bravo-Perez, Arda Durmaz, Zachary Brady, Luca Guarnera, Matteo D'Addona, Carmelo Gurnari, Chao-Yie Yang, Jaroslaw Maciejewski

Blood (2024) 144 (Supplement 1): 4096.

https://doi.org/10.1182/blood-2024-208366

Published: 2024

Journal Articles

Telomere Content Diversity in Myeloid Neoplasia Could Inform on Differential Sensitivity to Telomerase Inhibitors

Blood (2024) 144 (Supplement 1): 4104.

https://doi.org/10.1182/blood-2024-209923

Published: 2024

Journal Articles

Dysregulation of the Ubiquitination Pathway: Insights on Autoinflammatory Conditions and Inborn Errors of Immunity in Bone Marrow Failure Disorders

Zachary Brady, Nakisha D Williams, Arda Durmaz, Luca Guarnera, Matteo D'Addona, Aashray Mandala, Heesun J. Rogers, Carmelo Gurnari, Jaroslaw Maciejewski, Carlos Bravo-Perez, Valeria Visconte

Blood (2024) 144 (Supplement 1): 2675.

https://doi.org/10.1182/blood-2024-208405

Published: 2024

Journal Articles

Counterpoising Immune Pressure and Privilege: Paroxysmal Nocturnal Hemoglobinuria Evolutionary Dynamics

Hussein Awada, Arda Durmaz, Luca Guarnera, Tyler Birkholz, Olisaemeka Ogbue, Mark Orland, Olga Lytvynova, Matteo D'Addona, Praveena Thiagarajan, Arooj Ahmed, Zachary Brady, Carlos Bravo-Perez, Valeria Visconte, Jaroslaw Maciejewski, Carmelo Gurnari

Blood (2024) 144 (Supplement 1): 4085.

https://doi.org/10.1182/blood-2024-211518

Published: 2024

Journal Articles

An Immunogenetic Perspective on Bone Marrow Failure Syndromes: The KIR-HLA System

Aashray Mandala, Carlos Bravo-Perez, Matteo D'Addona, Zachary Brady, Mark Orland, Luca Guarnera, Kartik Lakhotiya, Christopher Haddad, Praveena Thiagarajan, Arooj Ahmed, Simona Pagliuca, Carmelo Gurnari, Valeria Visconte, Arda Durmaz, Jaroslaw Maciejewski

Blood (2024) 144 (Supplement 1): 4084.

https://doi.org/10.1182/blood-2024-210304

Published: 2024

Journal Articles

Oncogenic Nexus of TET2 with Thpok in Myeloid Neoplasia

Ejike Ujoatu, Sohini Mukhopadhyay, Carmelo Gurnari, Valeria Visconte, Jaroslaw Maciejewski, Jayati Basu, Babal K. Jha, H. Leighton Grimes, Stephen Sykes, Dietmar Kappes

Blood (2024) 144 (Supplement 1): 2716.

https://doi.org/10.1182/blood-2024-207759

Published: 2024

Journal Articles

Molecular Landscape of Multiple STAG2 Mutant Myeloid Malignancies

Matteo D'Addona, Eno-Obong B. Udoh, Luca Guarnera, Carlos Bravo-Perez, Serhan Unlu, Zachary Brady, Kartik Lakhotiya, Hussein Awada, Christopher Haddad, Aashray Mandala, Mark Orland, Arda Durmaz, Carmelo Gurnari, Aaron D. Viny, Jaroslaw Maciejewski, Valeria Visconte

Blood (2024) 144 (Supplement 1): 6696.

https://doi.org/10.1182/blood-2024-207614

Published: 2024

Journal Articles

Identification of Tumor Suppressors and Synthetic Lethal Targets in -7/del7q Myeloid Neoplasms By Iterative Computational Analysis Coupled with Experimental Validation

Daniel J Vail, Valeria Visconte, Babal K. Jha, Jill Durkin, Jaroslaw Maciejewski, Thomas Laframboise

Blood (2024) 144 (Supplement 1): 4303.

https://doi.org/10.1182/blood-2024-210881

Published: 2024

Journal Articles

Loss of TET2 Increases MHC Class I Expression in Acute Myeloid Leukemia

Xiaorong Gu, Songa Bae, Yahan Zhang, Nakisha D Williams, Dongxu Jiang, Simon Schlanger, Valeria Visconte, Jaroslaw Maciejewski, Babal K. Jha

Blood (2024) 144 (Supplement 1): 4159.

https://doi.org/10.1182/blood-2024-208348

Published: 2024

Journal Articles

Low-Count T-/NK-Large Granular Lymphocytic Leukemia: A Nosologically Distinct Disease Subtype at the Crossroads between Lymphoproliferation, Autoimmunity and Immunodeficiency

Carlos Bravo-Perez, Carmelo Gurnari, Arooj Ahmed, Naomi Kawashima, Zachary Brady, Matteo D'Addona, Luca Guarnera, Aashray Mandala, Kartik Lakhotiya, Christopher Haddad, Serhan Unlu, Mark Orland, Praveena Thiagarajan, Arda Durmaz, Valeria Visconte, Jaroslaw Maciejewski

Blood (2024) 144 (Supplement 1): 1688.

https://doi.org/10.1182/blood-2024-209437

Published: 2024

Journal Articles

Geno-Transcriptomic Topography of Clonal Drivers in Trisomy 8 Myeloid Malignancies

Hussein Awada, Carmelo Gurnari, Yasuo Kubota, Carlos Bravo-Perez, Luca Guarnera, Matteo D'Addona, Zachary Brady, Mark Orland, Serhan Unlu, Arda Durmaz, Hetty E. Carraway, Hassan Awada, Jaroslaw Maciejewski, Valeria Visconte

Blood (2024) 144 (Supplement 1): 2943.

https://doi.org/10.1182/blood-2024-209374

Published: 2024

Journal Articles

Unraveling Immunogenomic Features Germane to Pathobiology of Myelodysplastic Syndromes

Arda Durmaz, Zachary Brady, Kartik Lakhotiya, Benjamin Kroger, Hussein Awada, Yasuo Kubota, Jacky Chen, Colin Hercus, Sébastien Hergalant, Carlos Bravo-Perez, Maria Teresa Voso, Li Lily Wang, Jacob G. Scott, Hetty E. Carraway, Valeria Visconte, Stephen Chung, Simona Pagliuca, Jaroslaw Maciejewski, Carmelo Gurnari

Blood (2024) 144 (Supplement 1): 2224.

https://doi.org/10.1182/blood-2024-198530

Published: 2024

NARROW

Clinical and Molecular Insights into the Classification Dilemma: Are MDS/AML Cases Distinct from Secondary AML?

Genetic Determinants of Hypercoagulability in Complement and Hemostatic Systems Shape the Thrombotic Risk of Paroxysmal Nocturnal Hemoglobinuria

First Results of High Throughput Pipeline for Serotypic and TCR Clonotypic Specificities in Aplastic Anemia and Large Granular Lymphocyte Leukemia Uncovering Antigenic Peptides Relevant to Disease Etiology

Prediction of Post-Transplant Relapse of the Myelodysplastic Syndromes Via Evaluation of Stem Cells

Bi-Allelic DDX41 Mutations Exert Stage Specific Effects on Hematopoiesis to Promote Disease

Predictive Modeling of Hematopoietic Stem Cell Transplant Outcomes: Discovering the Role of Immunogenetic Features through Machine Learning Models

Could Somatic Gene Rescue Explain Frequency of Compound Heterozygous and Concurrent Receptor Tyrosine Kinase Mutations in Hematological Diseases?

Clinically Driven Algorithms Identify Patients with Large Granular Lymphocytic Leukemia at Risk of Significant Cytopenia Requiring Treatment

Genetic and Molecular Dynamics of DDX41- variants: Insights on the Variant Effect Prediction

Telomere Content Diversity in Myeloid Neoplasia Could Inform on Differential Sensitivity to Telomerase Inhibitors

Dysregulation of the Ubiquitination Pathway: Insights on Autoinflammatory Conditions and Inborn Errors of Immunity in Bone Marrow Failure Disorders

Counterpoising Immune Pressure and Privilege: Paroxysmal Nocturnal Hemoglobinuria Evolutionary Dynamics

An Immunogenetic Perspective on Bone Marrow Failure Syndromes: The KIR-HLA System

Oncogenic Nexus of TET2 with Thpok in Myeloid Neoplasia

Molecular Landscape of Multiple STAG2 Mutant Myeloid Malignancies

Identification of Tumor Suppressors and Synthetic Lethal Targets in -7/del7q Myeloid Neoplasms By Iterative Computational Analysis Coupled with Experimental Validation

Loss of TET2 Increases MHC Class I Expression in Acute Myeloid Leukemia

Low-Count T-/NK-Large Granular Lymphocytic Leukemia: A Nosologically Distinct Disease Subtype at the Crossroads between Lymphoproliferation, Autoimmunity and Immunodeficiency

Geno-Transcriptomic Topography of Clonal Drivers in Trisomy 8 Myeloid Malignancies

Unraveling Immunogenomic Features Germane to Pathobiology of Myelodysplastic Syndromes

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American Society of Hematology

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American Society of Hematology

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