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Journal Articles

Enhanced FLI1 accessibility mediates STAG2-mutant leukemogenesis

Free
Jane J Xu, Viviana Scoca, Yi Chen, Yingqian Zhang, Alexander Fischer, Eno-obong Udoh, Sebastian Fernando, Besmira Alija, John Pantazi, Varun Sudunagunta, Edna Stewart, Anabella Maria D, Michael Williams, Govind Bhagat, Claudia Gebhard, Valeria Visconte, Sarah Ondrejka, Ruud Delwel, Ming Hu, Richard Koche, Aaron Viny
Journal: Blood
Blood (2025) 146 (Supplement 1): 1467.
https://doi.org/10.1182/blood-2025-1467
Published: 2025
Journal Articles

Stag2 dependent chromatin remodeling enforces the erythroid-specific Gata1 cistrome

Free
Varun Sudunagunta, Edna Stewart, Yi Chen, Hongxia Yan, Sebastian Fernando, Viviana Scoca, Jane J Xu, Mohandas Narla, Aaron Viny
Journal: Blood
Blood (2025) 146 (Supplement 1): 968.
https://doi.org/10.1182/blood-2025-968
Published: 2025
Journal Articles

STAG2 mutation preserves a stem cell phenotype in FLT3-ITD-mediated MDS to leukemia transformation

Free
Jane J Xu, Yi Chen, John Pantazi, Sebastian Fernando, Besmira Alija, Varun Sudunagunta, Robert Bowman, Aaron Viny
Journal: Blood
Blood (2025) 146 (Supplement 1): 3242.
https://doi.org/10.1182/blood-2025-3242
Published: 2025
Journal Articles

Erythroid Dysplasia in Stag2 Deficient Murine Models Reveals Novel Erythropoietic Function for Stag2 Cohesin

Free
Varun S. Sudunagunta, Yi Chen, Russell Kunes, Edna M. Stewart, Viviana Scoca, John Pantazi, Hongxia Yan, Jane J. Xu, Mohandas Narla, Aaron D. Viny
Journal: Blood
Blood (2024) 144 (Supplement 1): 1070.
https://doi.org/10.1182/blood-2024-208693
Published: 2024
Journal Articles

Stag2 Loss Drives Abnormal Chromatin Remodeling with Fli1 Hyperactivity in Npm1c Leukemia

Free
Jane J. Xu, Viviana Scoca, Yi Chen, John Pantazi, Sebastian Fernando, Besmira Alija, Varun S. Sudunagunta, Aaron D. Viny
Journal: Blood
Blood (2024) 144 (Supplement 1): 2720.
https://doi.org/10.1182/blood-2024-211064
Published: 2024
Journal Articles

Synergy of Stag2-Cohesin Loss Results in Expansion of Npm1c-Mutant Hematopoietic Stem and Progenitor Cells

Free
Jane J Xu, Yi Chen, John Pantazi, Sebastian Fernando, Besmira Alija, Varun Sudunagunta, Govind Bhagat, Aaron D. Viny
Journal: Blood
Blood (2023) 142 (Supplement 1): 954.
https://doi.org/10.1182/blood-2023-190627
Published: 2023
Journal Articles

Stag2-Cohesin Loss Attenuates Flt3 ITD Myeloid Blast Expansion Yet Preserves Mutant HSC

Free
Jane J Xu, Yi Chen, John Pantazi, Sebastian Fernando, Besmira Alija, Varun Sudunagunta, Govind Bhagat, Robert L. Bowman, Aaron D. Viny
Journal: Blood
Blood (2023) 142 (Supplement 1): 2756.
https://doi.org/10.1182/blood-2023-190702
Published: 2023
Journal Articles

Cohesin Dependency in Npm1 c/+ and Flt3 -ITD Mutant Hematopoietic Stem and Progenitor Cells

Free
Jane J Xu, Besmira Alija, Stephanie Braunstein, John Pantazi, Varun S Sudunagunta, Robert L. Bowman, Aaron D Viny
Journal: Blood
Blood (2022) 140 (Supplement 1): 8690–8691.
https://doi.org/10.1182/blood-2022-169728
Published: 2022
Journal Articles

High Throughput Epigenomic Mapping of Hematopoietic Stem and Progenitor Cells Using Low Cell Input Acoustic Enhanced Immunoprecipitation

Free
Besmira Alija, Varun S Sudunagunta, Laura E Mittleman, John Pantazi, Stephanie Braunstein, Jane J Xu, Tom O'Hare, Angela Garding, Aaron D Viny
Journal: Blood
Blood (2022) 140 (Supplement 1): 10718–10719.
https://doi.org/10.1182/blood-2022-162740
Published: 2022
Journal Articles

Dysplastic Erythropoiesis in Stag2 Loss Exhibits Defective Nuclear Condensation and Hemophagocytosis

Free
Varun S Sudunagunta, Yi Chen, Jane J Xu, Laura E Mittelman, Hongxia Yan, John Pantazi, Stephanie Braunstein, Besmira Alija, Mohandas Narla, Aaron D Viny
Journal: Blood
Blood (2022) 140 (Supplement 1): 698–699.
https://doi.org/10.1182/blood-2022-162521
Published: 2022