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Journal Articles

Can Emergency Hematopoiesis Due to Sepsis Lead to Clonal Hematopoiesis? Implications for Understanding the Pathogenesis of Clonal Evolution

Olisaemeka Ogbue, Tariq Kewan, Omar Mehkri, Francois Fadell, Ishani Nautiyal, Megan Reynold, Arda Durmaz, Jennifer VanOudenhove, Hussein Awada, Serhan Unlu, Abhay Singh, Valeria Visconte, Lourdes Mendez, David S. Bosler, Abhijit Duggal, Stephanie Halene, Jaroslaw P. Maciejewski, Mohammed J Al-Jaghbeer, Carmelo Gurnari

Blood (2023) 142 (Supplement 1): 2691.

https://doi.org/10.1182/blood-2023-187424

Published: 2023

Journal Articles

Insights into Large Granular Lymphocytic Leukemia-Associated Hemolytic Anemia: Clinical Associations, Therapeutic Responses, and Optimal Management Strategies from a Large Institutional Study

Olisaemeka Ogbue, Serhan Unlu, Danai Dima, Carlos Bravo-Perez, Nakisha D Williams, Arooj Ahmed, Sindhusha Veeraballi, Arda Durmaz, Fauzia Ullah, Carmelo Gurnari, Valeria Visconte, Jaroslaw P. Maciejewski

Blood (2023) 142 (Supplement 1): 5167.

https://doi.org/10.1182/blood-2023-186071

Published: 2023

Journal Articles

Compound Heterozygosity Involving Other Dead ( DDX ) and Deah ( DHX ) Box Helicases Explains Seemingly Monoallelic Somatic and Germline DDX41 Mutations

Valeria Visconte, Carlos Bravo-Perez, Arda Durmaz, Luca Guarnera, Ishani Nautiyal, Megan Reynold, Nakisha D Williams, Yasuo Kubota, Naomi Kawashima, Benjamin Kroger, Stephen S. Chung, David S. Bosler, Carmelo Gurnari, Jaroslaw P. Maciejewski

Blood (2023) 142 (Supplement 1): 947.

https://doi.org/10.1182/blood-2023-187195

Published: 2023

Journal Articles

Molecular Landscape of c-CBL Mutation in Adults' Myeloid Malignancies

Luca Guarnera, Carmelo Gurnari, Carlos Bravo-Perez, Arda Durmaz, Nakisha D Williams, Hussein Awada, Naomi Kawashima, Arooj Ahmed, Serhan Unlu, Christopher Haddad, Aashray Mandala, Yasuo Kubota, Jaroslaw P. Maciejewski, Valeria Visconte

Blood (2023) 142 (Supplement 1): 4336.

https://doi.org/10.1182/blood-2023-184962

Published: 2023

Journal Articles

RUNX1 Germline Mutations of Autosomal-Dominant Familial Platelet Disorder Are More Common Than Expected in Adult Myeloid Leukemias Indicating Highly Variable Penetrance

Christopher Haddad, Yasuo Kubota, Carlos Bravo-Perez, Carmelo Gurnari, Luca Guarnera, Olisaemeka Ogbue, Arda Durmaz, Ishani Nautiyal, Aashray Mandala, David S. Bosler, Hetty E. Carraway, Yogen Saunthararajah, Valeria Visconte, Jaroslaw P. Maciejewski

Blood (2023) 142 (Supplement 1): 2736.

https://doi.org/10.1182/blood-2023-189420

Published: 2023

Journal Articles

Biallelic Landscape of DNMT3A Mutant Myeloid Neoplasia

Naomi Kawashima, Yasuo Kubota, Carmelo Gurnari, Carlos Bravo-Perez, Luca Guarnera, Nakisha D Williams, Arda Durmaz, Megan Reynold, Arooj Ahmed, Jaroslaw P. Maciejewski, Valeria Visconte

Blood (2023) 142 (Supplement 1): 1469.

https://doi.org/10.1182/blood-2023-181793

Published: 2023

Journal Articles

Bone Marrow Failure and Inborn Errors of Immunity: An Immunogenomic Crossroad

Carlos Bravo-Perez, Carmelo Gurnari, Luca Guarnera, Naomi Kawashima, Serhan Unlu, Aashray Mandala, Nakisha D Williams, Arooj Ahmed, Yasuo Kubota, Arda Durmaz, Valeria Visconte, Jaroslaw P. Maciejewski

Blood (2023) 142 (Supplement 1): 707.

https://doi.org/10.1182/blood-2023-183000

Published: 2023

Journal Articles

Unveiling the Spectrum of Inborn Errors of Immunity: Lessons from T-Cell LGL Clonal Expansions

Carlos Bravo-Perez, Carmelo Gurnari, Luca Guarnera, Naomi Kawashima, Serhan Unlu, Aashray Mandala, Mark Orland, Olisaemeka Ogbue, Nakisha D Williams, Arooj Ahmed, Yasuo Kubota, Arda Durmaz, Valeria Visconte, Jaroslaw P. Maciejewski

Blood (2023) 142 (Supplement 1): 154.

https://doi.org/10.1182/blood-2023-182344

Published: 2023

Journal Articles

Unraveling the Impact of 2022 Classifications on Secondary Acute Myeloid Leukemia: Assessing the True Qualification Power of Diagnostic Qualifiers

Enrico Attardi, Arianna Savi, Beatrice Borsellino, Marta Cipriani, Alfonso Piciocchi, Flavia Mallegni, Giorgia Silvestrini, Hussein Awada, Arda Durmaz, Valeria Visconte, Matteo Giovanni Della Porta, Adriano Venditti, Jaroslaw P. Maciejewski, Carmelo Gurnari, Maria Teresa Voso

Blood (2023) 142 (Supplement 1): 819.

https://doi.org/10.1182/blood-2023-185709

Published: 2023

Journal Articles

Geno-Multiomics Strategy Informs Drug Response Profiles in High-Risk Myeloid Neoplasia

Arda Durmaz, Sean Yetter, Tariq Kewan, Waled Bahaj, Carlos Bravo-Perez, Luca Guarnera, Naomi Kawashima, Hussein Awada, Carmelo Gurnari, Yasuo Kubota, Jacob Scott, Jaroslaw P. Maciejewski, Valeria Visconte

Blood (2023) 142 (Supplement 1): 5016.

https://doi.org/10.1182/blood-2023-190059

Published: 2023

Journal Articles

Association Vs Causation: Epidemiologic Clues As to the Autoimmune Pathogenesis of MDS

Nakisha D Williams, Arda Durmaz, Carlos Bravo-Perez, Yasuo Kubota, Megan Reynold, Michaela Witt, Luca Guarnera, Morgan Ferrel, Aashray Mandala, Naomi Kawashima, Carmelo Gurnari, Valeria Visconte, Jaroslaw P. Maciejewski

Blood (2023) 142 (Supplement 1): 4066.

https://doi.org/10.1182/blood-2023-181916

Published: 2023

Journal Articles

Differential Isoforms Signature of Splicing Factor Mutant Myeloid Neoplasia

Arda Durmaz, Carmelo Gurnari, Carlos Bravo-Perez, Luca Guarnera, Yasuo Kubota, Naomi Kawashima, Ishani Nautiyal, Sean Yetter, Nakisha D Williams, Serhan Unlu, Sindhusha Veeraballi, Arooj Ahmed, Chao-Yie Yang, John Barnard, Jacob Scott, Jaroslaw P. Maciejewski, Valeria Visconte

Blood (2023) 142 (Supplement 1): 5701.

https://doi.org/10.1182/blood-2023-184752

Published: 2023

Journal Articles

The Impact of KIR-HLA Interplay in T-LGL Leukemia

Aashray Mandala, Carlos Bravo-Perez, Nakisha D Williams, Christopher Haddad, Luca Guarnera, Simona Pagliuca, Serhan Unlu, Yasuo Kubota, Naomi Kawashima, Carmelo Gurnari, Valeria Visconte, Arda Durmaz, Jaroslaw P. Maciejewski

Blood (2023) 142 (Supplement 1): 1637.

https://doi.org/10.1182/blood-2023-189268

Published: 2023

Journal Articles

Outcome Prediction in DDX41 -Mutant Myelodysplastic Syndromes Is Not Possible with General Disease Schemes and Requires a Dedicated Risk Scoring System

Carmelo Gurnari, Hideki Makishima, Arda Durmaz, Ryunosuke Saiki, Guilherme Mendes Sapinho, Alex Bataller, Lukasz P. Gondek, Yasuhito Nannya, Steve Best, Pramila Krishnamurthy, Hussein Awada, Enrico Attardi, Valeria Visconte, Maria Teresa Voso, Amy E. DeZern, Guillermo Garcia-Manero, Austin Kulasekararaj, Jaroslaw P. Maciejewski, Seishi Ogawa

Blood (2023) 142 (Supplement 1): 316.

https://doi.org/10.1182/blood-2023-178116

Published: 2023

Journal Articles

Reverse Engineering of Antigenic Peptides in LGL to Decipher Disease Triggers

Arda Durmaz, Carmelo Gurnari, Simona Pagliuca, Colin Hercus, Carlos Bravo-Perez, Luca Guarnera, Nakisha D Williams, Danai Dima, Ishani Nautiyal, Yasuo Kubota, Naomi Kawashima, Jacob Scott, Valeria Visconte, Jaroslaw P. Maciejewski

Blood (2023) 142 (Supplement 1): 246.

https://doi.org/10.1182/blood-2023-190381

Published: 2023

Journal Articles

Somatic and Germline HLA Determinants of Immune Surveillance and Escape in Myelodysplastic Syndromes

Carmelo Gurnari, Arda Durmaz, Benjamin Kroger, Hussein Awada, Jacky Chen, Colin Hercus, Sébastien Hergalant, Carlos Bravo-Perez, Maria Teresa Voso, Jacob Scott, Valeria Visconte, Stephen S. Chung, Jaroslaw P. Maciejewski, Simona Pagliuca

Blood (2023) 142 (Supplement 1): 3220.

https://doi.org/10.1182/blood-2023-178890

Published: 2023

Journal Articles

LGL in MGUS or MGUS in LGL? Lessons of Nature and Their Clinical Implications

Carlos Bravo-Perez, Carmelo Gurnari, Naomi Kawashima, Danai Dima, Olisaemeka Ogbue, Luca Guarnera, Yasuo Kubota, Nakisha D Williams, Arooj Ahmed, Fauzia Ullah, Arda Durmaz, Megan Nakashima, Valeria Visconte, Jaroslaw P. Maciejewski

Blood (2023) 142 (Supplement 1): 4769.

https://doi.org/10.1182/blood-2023-181975

Published: 2023

Journal Articles

Maladaptive Somatic Rescue in FLT3 Mutations of Suspected Germline Nature

Arooj Ahmed, Luca Guarnera, Jaymeson Gordon, Carlos Bravo-Perez, Arda Durmaz, Yasuo Kubota, Naomi Kawashima, Mark Orland, Nakisha D Williams, Christopher Haddad, Serhan Unlu, Sean Yetter, Sindhusha Veeraballi, Aashray Mandala, Carmelo Gurnari, Valeria Visconte, Jaroslaw P. Maciejewski

Blood (2023) 142 (Supplement 1): 5666.

https://doi.org/10.1182/blood-2023-190837

Published: 2023

Journal Articles

Small-Molecule U2 Auxiliary Factor Homology Motif (UHM) Domain Inhibitors Cause Splicing Pattern Changes in U2AF1 Mutant Leukemia Cells and Induce Sub-G1 Cell Cycle Arrest

Chao-Yie Yang, Xinrui Yuan, Mona Kazemi Sabzvar, Arda Durmaz, Krishnapriya Chinnaswamy, Jeanne Stuckey, Seth J Corey, Jaroslaw P. Maciejewski, Valeria Visconte

Blood (2023) 142 (Supplement 1): 115.

https://doi.org/10.1182/blood-2023-190365

Published: 2023

Journal Articles

Genomic Analyses Unveil the Pathogenesis and Inform on Therapeutic Targeting in KMT2A -PTD AML

Yasuo Kubota, Megan Reynold, Nakisha D Williams, Naomi Kawashima, Carlos Bravo-Perez, Luca Guarnera, Christopher Haddad, Aashray Mandala, Carmelo Gurnari, Arda Durmaz, Valeria Visconte, Jaroslaw P. Maciejewski

Blood (2023) 142 (Supplement 1): 5696.

https://doi.org/10.1182/blood-2023-178875

Published: 2023

NARROW

Can Emergency Hematopoiesis Due to Sepsis Lead to Clonal Hematopoiesis? Implications for Understanding the Pathogenesis of Clonal Evolution

Insights into Large Granular Lymphocytic Leukemia-Associated Hemolytic Anemia: Clinical Associations, Therapeutic Responses, and Optimal Management Strategies from a Large Institutional Study

Compound Heterozygosity Involving Other Dead ( DDX ) and Deah ( DHX ) Box Helicases Explains Seemingly Monoallelic Somatic and Germline DDX41 Mutations

Molecular Landscape of c-CBL Mutation in Adults' Myeloid Malignancies

RUNX1 Germline Mutations of Autosomal-Dominant Familial Platelet Disorder Are More Common Than Expected in Adult Myeloid Leukemias Indicating Highly Variable Penetrance

Biallelic Landscape of DNMT3A Mutant Myeloid Neoplasia

Bone Marrow Failure and Inborn Errors of Immunity: An Immunogenomic Crossroad

Unveiling the Spectrum of Inborn Errors of Immunity: Lessons from T-Cell LGL Clonal Expansions

Unraveling the Impact of 2022 Classifications on Secondary Acute Myeloid Leukemia: Assessing the True Qualification Power of Diagnostic Qualifiers

Geno-Multiomics Strategy Informs Drug Response Profiles in High-Risk Myeloid Neoplasia

Association Vs Causation: Epidemiologic Clues As to the Autoimmune Pathogenesis of MDS

Differential Isoforms Signature of Splicing Factor Mutant Myeloid Neoplasia

The Impact of KIR-HLA Interplay in T-LGL Leukemia

Outcome Prediction in DDX41 -Mutant Myelodysplastic Syndromes Is Not Possible with General Disease Schemes and Requires a Dedicated Risk Scoring System

Reverse Engineering of Antigenic Peptides in LGL to Decipher Disease Triggers

Somatic and Germline HLA Determinants of Immune Surveillance and Escape in Myelodysplastic Syndromes

LGL in MGUS or MGUS in LGL? Lessons of Nature and Their Clinical Implications

Maladaptive Somatic Rescue in FLT3 Mutations of Suspected Germline Nature

Small-Molecule U2 Auxiliary Factor Homology Motif (UHM) Domain Inhibitors Cause Splicing Pattern Changes in U2AF1 Mutant Leukemia Cells and Induce Sub-G1 Cell Cycle Arrest

Genomic Analyses Unveil the Pathogenesis and Inform on Therapeutic Targeting in KMT2A -PTD AML

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American Society of Hematology

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American Society of Hematology

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