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Journal Articles

Novel approaches to identify cellular vulnerabilities in TET2-dependent MDS

Blood (2025) 146 (Supplement 1): 3838.

https://doi.org/10.1182/blood-2025-3838

Published: 2025

Journal Articles

Serum erythropoietin level as a selective pressure in clonal hematopoiesis: Insights into the mutational landscape of myeloid neoplasias

Zachary Brady, Charlotte Zurowski, Felipe de Almeida Sartori, Tariq Kewan, Olivia Hunyadi, Mark Orland, Aashray Mandala, Christopher Haddad, Hetty Carraway, Abhay Singh, Serhan Unlu, Atsushi Marumo, Kartik Lakhotiya, Carmelo Gurnari, Arda Durmaz, Valeria Visconte, Jaroslaw Maciejewski

Blood (2025) 146 (Supplement 1): 3174.

https://doi.org/10.1182/blood-2025-3174

Published: 2025

Journal Articles

Epidemiologic clues, current management and diagnostic trends in idiopathic budd-chiari syndrome: Implications of PNH and diagnostic testing

Aashray Mandala, Arda Durmaz, Mark Orland, Carlos Bravo-Perez, Zachary Brady, Matteo D'Addona, Kartik Lakhotiya, Christopher Haddad, Praveena Thiagarajan, Serhan Unlu, Felipe de Almeida Sartori, Selin Ilaslan, Valeria Visconte, Carmelo Gurnari, Jaroslaw Maciejewski

Blood (2025) 146 (Supplement 1): 1432.

https://doi.org/10.1182/blood-2025-1432

Published: 2025

Journal Articles

Global immunopeptidome remodeling favors piga mutant clones in bone marrow failure

Kartik Lakhotiya, Xiaorong Gu, Arda Durmaz, Aashray Mandala, Matteo D'Addona, Carlos Bravo-Perez, Mark Orland, Zachary Brady, Serhan Unlu, Atsushi Marumo, Praveena Thiagarajan, Christopher Haddad, Felipe de Almeida Sartori, ERSAN UNLU, Valeria Visconte, Carmelo Gurnari, Jaroslaw Maciejewski

Blood (2025) 146 (Supplement 1): 3207.

https://doi.org/10.1182/blood-2025-3207

Published: 2025

Journal Articles

TP53 mutational spectrum and fitness landscape in myeloid neoplasia

ERSAN UNLU, Waled Bahaj, Tariq Kewan, Carlos Bravo-Perez, Serhan Unlu, Zachary Brady, Asfand Yar Cheema, Olivia Hunyadi, Charlotte Zurowski, Atsushi Marumo, Kartik Lakhotiya, Felipe de Almeida Sartori, Aashray Mandala, Mark Orland, Luca Guarnera, Carmelo Gurnari, Jaroslaw Maciejewski, Valeria Visconte, Arda Durmaz

Blood (2025) 146 (Supplement 1): 4360.

https://doi.org/10.1182/blood-2025-4360

Published: 2025

Journal Articles

Machine learning-derived, comprehensive “Geno-Immunome” of bone marrow failure syndromes reveals complex immunogenetic interactions with clinical implications

Aashray Mandala, Carlos Bravo-Perez, Mark Orland, Zachary Brady, Serhan Unlu, Atsushi Marumo, Kartik Lakhotiya, Christopher Haddad, Felipe de Almeida Sartori, Asfand Yar Cheema, Simona Pagliuca, Carmelo Gurnari, Valeria Visconte, Arda Durmaz, Jaroslaw Maciejewski

Blood (2025) 146 (Supplement 1): 2583.

https://doi.org/10.1182/blood-2025-2583

Published: 2025

Journal Articles

Exploring the spectrum of non-malignant complications in germline DDX41-associated hematologic disorders

Valeria Visconte, Serhan Unlu, Mark Orland, Praveena Thiagarajan, Aashray Mandala, Matteo D'Addona, Olivia Hunyadi, Zachary Brady, Kartik Lakhotiya, Felipe de Almeida Sartori, Carmelo Gurnari, Arda Durmaz, Carlos Bravo-Perez, Jaroslaw Maciejewski

Blood (2025) 146 (Supplement 1): 1445.

https://doi.org/10.1182/blood-2025-1445

Published: 2025

Journal Articles

Unsupervised clustering of DDX41 mutants informs on the somatic landscape of single germline hits

Arda Durmaz, Carlos Bravo-Perez, Olivia Hunyadi, Zachary Brady, Luca Guarnera, Mark Orland, Serhan Unlu, Praveena Thiagarajan, Asfand Yar Cheema, Kartik Lakhotiya, Aashray Mandala, Felipe de Almeida Sartori, Matteo D'Addona, Jacob Scott, Carmelo Gurnari, Jaroslaw Maciejewski, Valeria Visconte

Blood (2025) 146 (Supplement 1): 1443.

https://doi.org/10.1182/blood-2025-1443

Published: 2025

Journal Articles

Investigating suspected germline STAG2 variants in myeloid neoplasms

Eno-obong Udoh, Yi Chen, Matteo D'Addona, Felipe de Almeida Sartori, Serhan Unlu, Zachary Brady, Jaroslaw Maciejewski, Valeria Visconte, Aaron Viny

Blood (2025) 146 (Supplement 1): 5609.

https://doi.org/10.1182/blood-2025-5609

Published: 2025

Journal Articles

Invariant patterns of global mutational signatures allow new fundamental insights in etiopathogenesis of bone marrow failure including aplastic anemia and myelodysplasia

Felipe de Almeida Sartori, Arda Durmaz, Carlos Bravo-Perez, Zachary Brady, Mark Orland, Aashray Mandala, Atsushi Marumo, Olivia Hunyadi, Eno-obong Udoh, Kartik Lakhotiya, Charlotte Zurowski, Paulo Campregher, Carmelo Gurnari, Thomas Laframboise, Valeria Visconte, Jaroslaw Maciejewski

Blood (2025) 146 (Supplement 1): 4985.

https://doi.org/10.1182/blood-2025-4985

Published: 2025

Journal Articles

Concurrent clonality of multiple hematopoietic lineages: Implications for pathogenesis and management of cytopenia

Carlos Bravo-Perez, Carmelo Gurnari, Aashray Mandala, Naomi Kawashima, Atsushi Marumo, Zachary Brady, Mark Orland, Serhan Unlu, Luca Guarnera, Matteo D'Addona, Praveena Thiagarajan, Felipe de Almeida Sartori, Kartik Lakhotiya, Megan Nakashima, Heesun Rogers, Arda Durmaz, Valeria Visconte, Jaroslaw Maciejewski

Blood (2025) 146 (Supplement 1): 1391.

https://doi.org/10.1182/blood-2025-1391

Published: 2025

Journal Articles

GLP‑1 receptor agonists and clonal hematopoiesis: Early human signals of anti‑inflammatory clone mitigation and lower MDS‑to‑AML progression

Mark Orland, Asfand Yar Cheema, Zachary Brady, Aashray Mandala, Felipe de Almeida Sartori, Luca Guarnera, Christopher Haddad, Kartik Lakhotiya, Carlos Bravo-Perez, Carmelo Gurnari, Valeria Visconte, Jaroslaw Maciejewski

Blood (2025) 146 (Supplement 1): 1385.

https://doi.org/10.1182/blood-2025-1385

Published: 2025

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Novel approaches to identify cellular vulnerabilities in TET2-dependent MDS

Serum erythropoietin level as a selective pressure in clonal hematopoiesis: Insights into the mutational landscape of myeloid neoplasias

Epidemiologic clues, current management and diagnostic trends in idiopathic budd-chiari syndrome: Implications of PNH and diagnostic testing

Global immunopeptidome remodeling favors piga mutant clones in bone marrow failure

TP53 mutational spectrum and fitness landscape in myeloid neoplasia

Machine learning-derived, comprehensive “Geno-Immunome” of bone marrow failure syndromes reveals complex immunogenetic interactions with clinical implications

Exploring the spectrum of non-malignant complications in germline DDX41-associated hematologic disorders

Unsupervised clustering of DDX41 mutants informs on the somatic landscape of single germline hits

Investigating suspected germline STAG2 variants in myeloid neoplasms

Invariant patterns of global mutational signatures allow new fundamental insights in etiopathogenesis of bone marrow failure including aplastic anemia and myelodysplasia

Concurrent clonality of multiple hematopoietic lineages: Implications for pathogenesis and management of cytopenia

GLP‑1 receptor agonists and clonal hematopoiesis: Early human signals of anti‑inflammatory clone mitigation and lower MDS‑to‑AML progression

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American Society of Hematology

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