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Journal Articles

Risk prediction for clonal cytopenia: multicenter real-world evidence

Clinical Trials & Observations
Zhuoer Xie, Rami Komrokji, Najla Al Ali, Alexandra Regelson, Susan Geyer, Anand Patel, Caner Saygin, Amer M. Zeidan, Jan Philipp Bewersdorf, Lourdes Mendez, Ashwin Kishtagari, Joshua F. Zeidner, Catherine C. Coombs, Yazan F. Madanat, Stephen Chung, Talha Badar, James Foran, Pinkal Desai, Charlton Tsai, Elizabeth A. Griffiths, Monzr M. Al Malki, Idoroenyi Amanam, Catherine Lai, H. Joachim Deeg, Lionel Ades, Cecilia Arana Yi, Afaf E. G. Osman, Shira Dinner, Yasmin Abaza, Justin Taylor, Namrata Chandhok, Deborah Soong, Andrew M. Brunner, Hetty E. Carraway, Abhay Singh, Chiara Elena, Jacqueline Ferrari, Anna Gallì, Sara Pozzi, Eric Padron, Mrinal M. Patnaik, Luca Malcovati, Michael R. Savona, Aref Al-Kali
Journal: Blood
Blood (2024) 144 (19): 2033–2044.
https://doi.org/10.1182/blood.2024024756
Published: 2024
Includes: Supplemental data
Journal Articles

Follow-up from the A041202 study shows continued efficacy of ibrutinib regimens for older adults with CLL

CME Clinical Trials & Observations
Jennifer A. Woyach, Gabriela Perez Burbano, Amy S. Ruppert, Cecelia Miller, Nyla A. Heerema, Weiqiang Zhao, Anna Wall, Wei Ding, Nancy L. Bartlett, Danielle M. Brander, Paul M. Barr, Kerry A. Rogers, Sameer A. Parikh, Deborah M. Stephens, Jennifer R. Brown, Gerard Lozanski, James Blachly, Sreenivasa Nattam, Richard A. Larson, Harry Erba, Mark Litzow, Selina Luger, Carolyn Owen, Charles Kuzma, Jeremy S. Abramson, Richard F. Little, Shira Dinner, Richard M. Stone, Geoffrey Uy, Wendy Stock, Sumithra J. Mandrekar, John C. Byrd
Journal: Blood
Blood (2024) 143 (16): 1616–1627.
https://doi.org/10.1182/blood.2023021959
Published: 2024
Includes: Supplemental data
Journal Articles

Consolidation Therapy with Blinatumomab Improves Overall Survival in Newly Diagnosed Adult Patients with B-Lineage Acute Lymphoblastic Leukemia in Measurable Residual Disease Negative Remission: Results from the ECOG-ACRIN E1910 Randomized Phase III National Cooperative Clinical Trials Network Trial

Mark R. Litzow, Zhuoxin Sun, Elisabeth Paietta, Ryan J. Mattison, Hillard M Lazarus, Jacob M. Rowe, Daniel A. Arber, Charles G. Mullighan, Cheryl L Willman, Yanming Zhang, Matthew Wieduwilt, Michaela Liedtke, Julie Bergeron, Keith W. Pratz, Shira Dinner, Noelle V. Frey, Steven D. Gore, Bhavana Bhatnagar, Ehab L. Atallah, Geoffrey L. Uy, Deepa Jeyakumar, Tara L. Lin, Richard F. Little, Selina M. Luger, Martin S. Tallman
Journal: Blood
Blood (2022) 140 (Supplement 2): LBA-1.
https://doi.org/10.1182/blood-2022-171751
Published: 2022
Journal Articles

Predictors of Long-Term Outcome in TP53 -Mutated Acute Myeloid Leukemia Patients Receiving Allogeneic Stem Cell Transplant after First- or Second-Line Therapy: Results from the Consortium on Myeloid Malignancies and Neoplastic Diseases (COMMAND)

Talha Badar, Ehab L. Atallah, Rory Michael Shallis, Antoine N. Saliba, Maximilian F. Stahl, Jan Philipp Bewersdorf, Justin Grenet, Anand Ashwin Patel, Yasmin Abaza, Guru Subramanian Guru Murthy, Adam S Duvall, Madelyn Burkart, Neil Palmisiano, Michal Jakub Kubiak, Vamsi K. Kota, Shira Dinner, Aaron D Goldberg, Mark R. Litzow
Journal: Blood
Blood (2022) 140 (Supplement 1): 1435–1437.
https://doi.org/10.1182/blood-2022-167731
Published: 2022
Journal Articles

Venetoclax (VEN) Plus Intensive Chemotherapy (IC) with FLAG-IDA in Patients (Pts) with Newly Diagnosed (ND) and Relapsed/Refractory (R/R) Acute Myeloid Leukemia (AML)

Yasmin Abaza, Talha Khan, Shira Dinner, Olga Frankfurt, Jessica K. Altman
Journal: Blood
Blood (2022) 140 (Supplement 1): 9036–9038.
https://doi.org/10.1182/blood-2022-168437
Published: 2022
Journal Articles

Clinical Outcomes of Patients with TP53 -Mutated AML after First Relapse or with Primary Refractory Disease: Results from Consortium on Myeloid Malignancies and Neoplastic Diseases (COMMAND)

Talha Badar, Ehab L. Atallah, Antoine N. Saliba, Rory Michael Shallis, Maximilian F. Stahl, Jan Philipp Bewersdorf, Guillerhme Sacchi De Camargo Correia, Anand Ashwin Patel, Yasmin Abaza, Guru Subramanian Guru Murthy, Adam S Duvall, Madelyn Burkart, Neil Palmisiano, Danielle Bradshaw, Vamsi K. Kota, Shira Dinner, Aaron D Goldberg, Mark R. Litzow
Journal: Blood
Blood (2022) 140 (Supplement 1): 6058–6060.
https://doi.org/10.1182/blood-2022-163795
Published: 2022
Journal Articles

Ameli-01: A Phase I Trial of UCART123v1.2, an Anti-CD123 Allogeneic CAR-T Cell Product, in Adult Patients with Relapsed or Refractory (R/R) CD123+ Acute Myeloid Leukemia (AML)

David A. Sallman, Daniel J. DeAngelo, Naveen Pemmaraju, Shira Dinner, Saar Gill, Rebecca L. Olin, Eunice S. Wang, Marina Konopleva, Eileen Stark, Ana Korngold, Asifa Haider, Kate Backhouse, Carolyn Figliola, Daniel J. Lee, Mark G. Frattini, Carrie Brownstein, Gail J. Roboz
Journal: Blood
Blood (2022) 140 (Supplement 1): 2371–2373.
https://doi.org/10.1182/blood-2022-169928
Published: 2022
Journal Articles

The Characteristics and Prognosis of Patients with Clonal Cytopenias of Undetermined Significance, Including Cancer and Therapy-Related Clonal Cytopenias

Zhuoer Xie, Alexandra Smith, Rami S. Komrokji, Najla Al Ali, Anand Ashwin Patel, Caner Saygin, Amer M. Zeidan, Jan Philipp Bewersdorf, Ashwin Kishtagari, Joshua F. Zeidner, Catherine C. Coombs, Yazan F. Madanat, James M. Foran, Talha Badar, Pinkal Desai, Charlton Tsai, Elizabeth A. Griffiths, Monzr M. Al Malki, Idoroenyi Amanam, Catherine Lai, Joachim Deeg, Lionel Ades, Cecilia Arana Yi, Afaf Osman, Shira Dinner, Yasmin Abaza, Namrata Chandhok, Deborah Soong, Justin Taylor, Andrew M. Brunner, Hetty E. Carraway, Abhay Singh Singh, Susan M. Geyer, Eric Padron, Mrinal M.M. Patnaik, Michael R. Savona, Aref Al-Kali
Journal: Blood
Blood (2022) 140 (Supplement 1): 2887–2890.
https://doi.org/10.1182/blood-2022-162367
Published: 2022
Journal Articles

A Phase II Study of Lenalidomide, Ixazomib, Dexamethasone, and Daratumumab in Transplant-Ineligible Patients with Newly Diagnosed Multiple Myeloma (AFT-41)

Elizabeth K. O'Donnell, Vera Jean Suman, Susan M. Geyer, Omar Nadeem, Shira Dinner, Andrew J. Yee, Jacob P. Laubach, Clifton C. Mo, Sascha A. Tuchman, Kristen Donadio, Sarah Sinclair, Noopur S. Raje, Paul G. Richardson
Journal: Blood
Blood (2021) 138 (Supplement 1): 4776.
https://doi.org/10.1182/blood-2021-146274
Published: 2021
Journal Articles

Comparing Outcomes between Liposomal Daunorubicin/Cytarabine (CPX-351) and HMA+Venetoclax As Frontline Therapy in Acute Myeloid Leukemia

Justin Grenet, Akriti G Jain, Madelyn Burkart, Julian Waksal, Christopher Famulare, Yazan Numan, Maximilian Stahl, Zoe Mckinnell, Brian Ball, Xiaoyue Ma, Paul J Christos, Ellen Ritchie, Michael B. Samuel, Justin D. Kaner, Sangmin Lee, Aaron D Goldberg, Shira Dinner, Kendra Sweet, Gail J. Roboz, Pinkal Desai
Journal: Blood
Blood (2021) 138 (Supplement 1): 32.
https://doi.org/10.1182/blood-2021-145947
Published: 2021
Journal Articles

Maximal Tolerated Dose Determined for Venetoclax in Combination with Liposomal Vincristine in Patients with Relapsed or Refractory Ph-Negative T-Cell or B-Cell Acute Lymphoblastic Leukemia: Results of Phase 1 Portion of ECOG-ACRIN EA9152

Neil Palmisiano, Ju-Whei Lee, David F. Claxton, Elisabeth Paietta, Hassan B. Alkhateeb, Jae H Park, Nikolai Podoltsev, Ehab L. Atallah, Dale G Schaar, Shira Dinner, Jonathan Webster, Selina M. Luger, Mark R. Litzow
Journal: Blood
Blood (2021) 138 (Supplement 1): 3407.
https://doi.org/10.1182/blood-2021-153621
Published: 2021
Journal Articles

Myeloid Sarcoma Reveals a Unique Tumor Micro-Environment and Differential Prognosis Based on Transplant Status and Type of Treatment Received

Yazan Numan, Hamza Tariq, Jie Fan, Ping Xie, Madelyn Burkart, Yasmin Abaza, Yi-Hua Chen, Shira Dinner, Olga Frankfurt, Jayesh Mehta, Hui Zhang, Jessica K. Altman, Bin Zhang
Journal: Blood
Blood (2021) 138 (Supplement 1): 3432.
https://doi.org/10.1182/blood-2021-149173
Published: 2021
Journal Articles

Structural and Social Barriers to Survival in Adolescent and Young Adult (AYA) Patients with Acute Myeloid Leukemia (AML)

Madelyn Burkart, Ivy Abraham, Garth Rauscher, Nepheli Raptis, Maryam Zia, Anand Ashwin Patel, Ami Dave, Stephanie Berg, Wendy Stock, Melissa L. Larson, William B Pearse, Jessica K. Altman, Irum Khan, Shira Dinner
Journal: Blood
Blood (2021) 138 (Supplement 1): 844.
https://doi.org/10.1182/blood-2021-151677
Published: 2021
Journal Articles

Outcomes and Predictors of Relapse with Use of Hypomethylating Agents in Combination with Venetoclax Prior to Allogeneic Transplant in Acute Myeloid Leukemia

Imran Nizamuddin, Timothy Seijung Oh, Yazan Numan, Max Farber Kelsten, Madelyn Burkart, Olga Frankfurt, Carlos E. Vigil, Yasmin Abaza, Jessica K. Altman, Shira Dinner
Journal: Blood
Blood (2021) 138 (Supplement 1): 2327.
https://doi.org/10.1182/blood-2021-150815
Published: 2021
Journal Articles

Outcomes in Patients with Hematologic Malignancies Infected with Sars-Cov-2: The Northwestern University Experience

Carlos Galvez, MD, Imran Nizamuddin, MD, Emily Tuchman, MD, Peter Doukas, MD, Neha Reddy, MD, Jessica K. Altman, MD, Jane N. Winter, MD, Leo I. Gordon, MD, Dylan Barth, PharmD, BCPS, Nicole Hodgins, Barbara Pro, MD, Shuo Ma, MD PhD, Shira Dinner, MD, Olga Frankfurt, MD, Jayesh Mehta, MD, Seema Singhal, MD, Kehinde Adekola, MBBS,MS, Jonathan Moreira, MD, Sajal D Tanna, MD MPH, Firas Wehbe, MD PhD, Reem Karmali, MDMSc
Journal: Blood
Blood (2020) 136 (Supplement 1): 14–16.
https://doi.org/10.1182/blood-2020-139495
Published: 2020
Journal Articles

Gilteritinib Remains Clinically Active in Relapsed/Refractory FLT3 Mutated AML Previously Treated with FLT3 inhibitors

Yazan Numan, MD, Zaid Abdel Rahman, MD, Justin Grenet, MD, Stephanie Boisclair, MD, Jan Philipp Bewersdorf, MD, Dylan Barth, PharmD, BCPS, Amer M. Zeidan, MBBS, MHS, Musa Yilmaz, MD, Shira Dinner, MD, Yehuda E. Deutsch, MD, Olga Frankfurt, MD, Mark Litzow, MD, Aref Al-Kali, MD, James M. Foran, MD, Lisa Z. Sproat, MD, Borko Jovanovic, PhD, Naval Daver, MD, Alexander E. Perl, MD, Jessica K. Altman, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 5–7.
https://doi.org/10.1182/blood-2020-137251
Published: 2020
Journal Articles

Real World Outcomes of Adult B-Cell Acute Lymphocytic Leukemia Patients Treated with Inotuzumab Ozogamicin

Talha Badar, MD, Aniko Szabo, PhD, Martha Wadleigh, MD, Michaela Liedtke, MD, Shukaib Arslan, MD, Caitlin Siebenaller, PharmD, Ibrahim Aldoss, MD, Elizabeth Schultz, Mehrdad Hefazi, MD, Mark Litzow, MD, Eric Kuo, Amy Wang, MD MPH, Emily K Curran, MD, Rory M Shallis, MD, Nikolai A. Podoltsev, MD PhD, Suresh Kumar Balasubramanian, MD, Jay Yang, MD, Ryan J. Mattison, MD, Madelyn Burkart, MD, Shira Dinner, Anjali S. Advani, MD, Ehab L. Atallah, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1302.
https://doi.org/10.1182/blood-2019-124882
Published: 2019
Journal Articles

Olutasidenib (FT-2102) Induces Rapid Remissions in Patients with IDH1-Mutant Myelodysplastic Syndrome: Results of Phase 1/2 Single Agent Treatment and Combination with Azacitidine

Jorge E. Cortes, MD, Eunice S. Wang, MD, Justin M. Watts, MD, Sangmin Lee, MD, Maria R. Baer, MD, Kim-Hien Dao, DO, PhD, Shira Dinner, MD, Jay Yang, MD, William B. Donnellan, MD, Anthony P Schwarer, MD MBBS (Hons), FRACP, FRCPA, Christian Recher, MD PhD, Patrick Kelly, MD, Jennifer Sweeney, Julie Brevard, Patrick Henrick, Sanjeev Forsyth, Sylvie Guichard, Hesham Mohamed, MD, Andrew H. Wei, PhD FRACP, FRCPA, MBBS
Journal: Blood
Blood (2019) 134 (Supplement_1): 674.
https://doi.org/10.1182/blood-2019-124360
Published: 2019
Journal Articles

Olutasidenib (FT-2102), an IDH1m Inhibitor As a Single Agent or in Combination with Azacitidine, Induces Deep Clinical Responses with Mutation Clearance in Patients with Acute Myeloid Leukemia Treated in a Phase 1 Dose Escalation and Expansion Study

Justin M. Watts, MD, Maria R. Baer, MD, Jay Yang, MD, Thomas Prebet, MD PhD, Sangmin Lee, MD, Gary J. Schiller, MD, Shira Dinner, MD, Arnaud Pigneux, Pau Montesinos, MD PhD, Eunice S. Wang, MD, Karen Seiter, MD, Andrew H. Wei, PhD FRACP, FRCPA, MBBS, Stephane De Botton, Montserrat Arnan Sangerman, William B. Donnellan, MD, Brian A Jonas, MD PhD, Paul Brent Ferrell, Jr., MD, Kim-Hien Dao, DO, PhD, Patrick Kelly, MD, Jennifer Sweeney, Sanjeev Forsyth, Sylvie Guichard, Julie Brevard, Patrick Henrick, Hesham Mohamed, MD, Jorge E. Cortes, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 231.
https://doi.org/10.1182/blood-2019-123920
Published: 2019
Journal Articles

Real World Outcomes of Adult B-Cell Acute Lymphocytic Leukemia Patients Treated with Blinatumomab

Talha Badar, MD, Aniko Szabo, PhD, Anjali S. Advani, MD, Martha Wadleigh, MD, Shukaib Arslan, MD, Muhammad Khan, Ibrahim Aldoss, MD, Caitlin Siebenaller, PharmD, Elizabeth Schultz, Mehrdad Hefazi, MD, Rory M Shallis, MD, Ilana Yurkiewicz, MD BS, Nikolai A. Podoltsev, MD PhD, Anand Ashwin Patel, MD, Emily K Curran, MD, Suresh Kumar Balasubramanian, MD, Jay Yang, MD, Ryan J. Mattison, MD, Madelyn Burkart, MD, Shira Dinner, Michaela Liedtke, MD, Mark Litzow, MD, Ehab L. Atallah, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3809.
https://doi.org/10.1182/blood-2019-125466
Published: 2019