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Karen W.L. Yee
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Journal Articles

Analysis of hematologic improvement (HI) by time to response in Relapsed/Refractory Acute Myeloid Leukemia (AML) patients treated with olutasidenib

Free
Shira Dinner, Brian Jonas, Antonio Curti, Stephane De Botton, Pau Montesinos, Karen W.L. Yee, Gail Roboz, William Blum, Gary Schiller, Jorge Cortes, Justin Watts, Andrew Wei, Aaron Sheppard, Hua Tian, Eunice Wang
Journal: Blood
Blood (2025) 146 (Supplement 1): 3439.
https://doi.org/10.1182/blood-2025-3439
Published: 2025
Journal Articles

Comparable remission rates in therapy-related and myelodysplasia-related Acute Myeloid Leukemia (AML) versus de novo AML treated with azacitidine and venetoclax: A contemporary real-world study.

Free
Zahra AlHaj Issa, Cristiano Machado De Freitas, Aarya Murali, Akhil Rajendra, Dawn Maze, Aniket Banker, Steven Chan, Marta Davidson, Aaron Schimmer, Andre Schuh, Hassan Sibai, Karen W.L. Yee, Mark Minden, Vikas Gupta, Maria Perusini, Guillaume Richard-Carpentier
Journal: Blood
Blood (2025) 146 (Supplement 1): 3390.
https://doi.org/10.1182/blood-2025-3390
Published: 2025
Journal Articles

Extramedullary disease in AML: A high-risk feature beyond ELN 2022 classification

Free
Yael Morgenstern, Claire Andrews, Eshetu Atenafu, Steven Chan, Vikas Gupta, Mark Minden, Dawn Maze, Aaron Schimmer, Andre Schuh, Karen W.L. Yee, Hassan Sibai
Journal: Blood
Blood (2025) 146 (Supplement 1): 3388.
https://doi.org/10.1182/blood-2025-3388
Published: 2025
Journal Articles

Morphologic leukemia-free state (MLFS) is associated with inferior outcomes in patients with Acute Myeloid Leukemia (AML) treated with front-line azacitidine plus venetoclax

Free
Aarya Murali, Zahra AlHaj Issa, Cristiano Machado De Freitas, Akhil Rajendra, Marta Davidson, Aniket Bankar, Hassan Sibai, Maria Perusini, Steven Chan, Aaron Schimmer, Mark Minden, Karen W.L. Yee, Andre Schuh, Vikas Gupta, Dawn Maze, Guillaume Richard-Carpentier
Journal: Blood
Blood (2025) 146 (Supplement 1): 3508.
https://doi.org/10.1182/blood-2025-3508
Published: 2025
Journal Articles

Prognostic relevance of multiparameter flow cytometry-based MRD assessment in patients with FLT3-ITD mutated AML considering concomitant mutations including DNMT3A/NPM1/WT1 mutation

Free
Josephine Anne Lucero, Maria Perusini, Aniket Bankar, Marta Davidson, Guillaume Richard-Carpentier, Aaron Schimmer, Andre Schuh, Dawn Maze, Karen W.L. Yee, Mark Minden, Steven Chan, Jose-Mario Capo-Chichi, Vikas Gupta, Hassan Sibai, Anne Tierens, Dennis Kim
Journal: Blood
Blood (2025) 146 (Supplement 1): 7051.
https://doi.org/10.1182/blood-2025-7051
Published: 2025
Journal Articles

A comparison of overall survival and quality of life in MDS patients treated with azacytidine vs decitabine: A propensity matched registry Study

Free
James England, Liying Zhang, Michelle Geddes, Mitchell Sabloff, Grace Christou, Eve St-Hilaire, Nicholas Finn, Nancy Zhu, Brian Leber, Alejandro Garcia-Horton, Amy Trottier, April Shamy, Heather Leitch, Brett Houston, Ivan Landego, Karen W.L. Yee, Thomas Nevill, John Storring, Mohamed Elemary, Robert Delage, Laura Anne Habib, Lisa Chodirker, Signy Chow, Matthew Cheung, Lee Mozessohn, James Kennedy, Rena Buckstein
Journal: Blood
Blood (2025) 146 (Supplement 1): 3862.
https://doi.org/10.1182/blood-2025-3862
Published: 2025
Journal Articles

Real-world evidence evaluation of the safety and efficacy of intensive chemotherapy with or without gemtuzumab ozogamicin (GO) in patients with newly diagnosed Acute Myeloid Leukemia (AML) and favorable or intermediate risk cytogenetics

Free
Elizabeth Herrity, Dawn Maze, Marta Davidson, Aniket Bankar, Maria Perusini, Hassan Sibai, Steven Chan, Aaron Schimmer, Mark Minden, Karen W.L. Yee, Andre Schuh, Vikas Gupta, Guillaume Richard-Carpentier
Journal: Blood
Blood (2025) 146 (Supplement 1): 5240.
https://doi.org/10.1182/blood-2025-5240
Published: 2025
Journal Articles

Prognostic impact of molecular genetic and cytogenetic alterations in newly diagnosed acute myeloid leukemia treated with azacitidine and venetoclax: A real-world cohort study

Free
Cristiano Machado De Freitas, Aarya Murali, Zahra AlHaj Issa, Aniket Bankar, Hassan Sibai, Maria Perusini, Aaron Schimmer, Mark Minden, Steven Chan, Karen W.L. Yee, Andre Schuh, Vikas Gupta, Dawn Maze, Marta Davidson, Guillaume Richard-Carpentier
Journal: Blood
Blood (2025) 146 (Supplement 1): 4776.
https://doi.org/10.1182/blood-2025-4776
Published: 2025
Journal Articles

Mixed phenotype acute leukemia: Clinical characteristics and real-world outcomes

Free
Ana Patiño, Hong Chang, Mark Turingan, Aniket Bankar, Jonathan Wei, Marta Davidson, Guillaume Richard-Carpentier, Mark Minden, Andre Schuh, Karen W.L. Yee, Vikas Gupta, Dawn Maze, Steven Chan, Aaron Schimmer, Claire Andrews, Hassan Sibai, Maria Perusini
Journal: Blood
Blood (2025) 146 (Supplement 1): 3330.
https://doi.org/10.1182/blood-2025-3330
Published: 2025
Journal Articles

FLT3 inhibition with midostaurin offsets poor prognosis in NPM1/FLT3/DNMT3a triple-mutated AML

Free
Akhil Rajendra, Dawn Maze, Aniket Bankar, Steven Chan, Marta Davidson, Vikas Gupta, Mark Minden, Maria Perusini, Guillaume Richard-Carpentier, Aaron Schimmer, Andre Schuh, Elliot Smith, Karen W.L. Yee, Hassan Sibai
Journal: Blood
Blood (2025) 146 (Supplement 1): 1672.
https://doi.org/10.1182/blood-2025-1672
Published: 2025
Journal Articles

Grip strength predicts overall survival of patients with myelodysplastic syndrome in a multivariable model

Free
Nicholas Chornenki, Lisa Chodirker, Lee Mozessohn, Signy Chow, James Kennedy, James England, Jennifer Teichman, Matthew Cheung, Michelle Geddes, Mitchell Sabloff, Grace Christou, Eve St-Hilaire, Nicholas Finn, Nancy Zhu, Brian Leber, Alejandro Garcia-Horton, Amy Trottier, April Shamy, Heather Leitch, Brett Houston, Ivan Landego, Karen W.L. Yee, Thomas Nevill, John Storring, Mohamed Elemary, Laura Anne Habib, Robert Delage, Mohammed Siddiqui, Liying Zhang, Rena Buckstein
Journal: Blood
Blood (2025) 146 (Supplement 1): 964.
https://doi.org/10.1182/blood-2025-964
Published: 2025
Journal Articles

Reclassification of Ascertain (ASTX727-02) Myelodysplastic Syndrome (MDS) Patients: Outcomes Including Clinical Response, Overall Survival (OS), and Leukemia Free Survival (LFS) Based on IPSS-R and IPSS-M Scoring Systems

Free
Guillermo Garcia-Manero, James McCloskey, Elizabeth A. Griffiths, Amer M. Zeidan, Karen W.L. Yee, Aref Al-Kali, H. Joachim Deeg, Prapti A. Patel, Mitchell Sabloff, Mary-Margaret Keating, Nancy Zhu, Nashat Y. Gabrail, Salman Fazal, Joseph J. Maly, Olatoyosi Odenike, Hagop M. Kantarjian, Amy E. DeZern, Casey L. O'Connell, Gail J. Roboz, Lambert Busque, Rena Buckstein, Harsh Amin, Jasleen K. Randhawa, Brian Leber, Shannon Lee, Winny Chan, Sonia Souza, Yuri Sano, Harold N. Keer, Michael R. Savona
Journal: Blood
Blood (2023) 142 (Supplement 1): 4619.
https://doi.org/10.1182/blood-2023-188258
Published: 2023
Journal Articles

CPX351 Has Short Remission Duration but Is an Effective Bridge to Allogeneic Transplant in High Risk AML: Results from Canadian Real-World Multi-Centre Study

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Claire Andrews, Taylor Young, Eshetu G Atenafu, M.Sc., P.Stat, Sarit E Assouline, MD MSc, Joseph M Brandwein, MD, Steven M Chan, MD PhD, Signy Chow, MD FRCP(C), Dina Khalaf, BSc, MSc, MD, Vikas Gupta, MD FRCP, FRCPath, Dennis Dong Hwan Kim, MD, Dawn Maze, MDFRCPC,MSc, Mark D. Minden, Caroline J McNamara, MBBS, Tracy Murphy, MDFRCP,FRCPath, David Sanford, MD, Aaron D Schimmer, MD PhD, Andre C. Schuh, Karen W.L. Yee, MD, Hassan Sibai, MBBS
Journal: Blood
Blood (2020) 136 (Supplement 1): 6–7.
https://doi.org/10.1182/blood-2020-142990
Published: 2020
Journal Articles

Inferior Outcomes with a High LSC17 Score Can be Improved with Flag-IDA

Free
Tracy Murphy, MDFRCP,FRCPath, Stanley W.K. Ng, PhD, Ian King, PhD, Tong Zhang, Andrea Arruda, MSc, Narmin Ibrahimova, Jaime O. Claudio, PhD, Fiona Ferrera, Kristele Pan, Chantal Rockwell, Zhibin Lu, Natalie Stickle, Carl Virtanen, MSc, Vikas Gupta, MD FRCP, FRCPath, Dawn Maze, MDFRCPC,MSc, Caroline J McNamara, MBBS, Aaron D Schimmer, MD PhD, Andre C. Schuh, Hassan Sibai, MBBS, Karen W.L. Yee, MD, Dina Khalaf, BSc, MSc, MD, Brian Leber, MD, Mitchell Sabloff, MSc,MDFRCPC, Anne Tierens, MD PhD, Mark D. Minden, Tracy L. Stockley, PhD FCCMG, FACMG, Steven M Chan, MD PhD, Jean C.Y. Wang, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 35–36.
https://doi.org/10.1182/blood-2020-138943
Published: 2020
Journal Articles

High Transfusion Dependence and Serum Ferritin but Not Transferrin Saturation Predict Inferior Clinical Outcomes in Patients with MDS

Free
Jennifer Teichman, MD, Michelle Geddes, MD, Nancy Zhu, MD, Mary-Margaret Keating, MD FRCPC, Mitchell Sabloff, MSc,MDFRCPC, Grace Christou, MD, Brian Leber, MD, Dina Khalaf, BSc, MSc, MD, Eve St-Hilaire, MD, Nicholas Finn, MD, April Shamy, MD, Karen W.L. Yee, MD, John M. Storring, MD, Thomas J. Nevill, MD, Robert Delage, MD, Mohamed Elemary, MD, Versha Banerji, MD, Lee Mozessohn, MD, Lisa Chodirker, MD, Liying Zhang, PhD, Mohammed Siddiqui, Anne Parmentier, BA, Heather A. Leitch, MD, Rena J. Buckstein, MD FRCPC
Journal: Blood
Blood (2020) 136 (Supplement 1): 47–48.
https://doi.org/10.1182/blood-2020-140065
Published: 2020
Journal Articles

Prognostic Role of Multiparameter Flow Cytometry-Based Measurable Residual Disease Assessment in Patients with Acute Myeloid Leukemia Harboring DNMT3A/TET2/ASXL1 Mutation

Free
Muhned Alhumaid, MD, Georgina S. Daher-Reyes, MD, Aaron D Schimmer, MD PhD, Andre C. Schuh, Anne Tierens, MD PhD, Caroline J McNamara, MBBS, Dawn Maze, MDFRCPC,MSc, Igor Nicolas Novitzky-Basso, MDPhDMRCP,FRCPath, Karen W.L. Yee, MD, Mark D. Minden, Steven M Chan, MD PhD, Tracy Murphy, MDFRCP,FRCPath, Vikas Gupta, MD FRCP, FRCPath, Dennis Dong Hwan Kim, MD, Hassan Sibai, MBBS
Journal: Blood
Blood (2020) 136 (Supplement 1): 8–9.
https://doi.org/10.1182/blood-2020-138862
Published: 2020
Journal Articles

Preliminary Results from a Phase 1 Study of Cfi-400495, a PLK4 Inhibitor, in Patients with Acute Myeloid Leukemia and High Risk MDS

Free
Tracy Murphy, MDFRCP,FRCPath, Brian Leber, MD, Mark R Bray, Steven M Chan, MD PhD, Vikas Gupta, MD FRCP, FRCPath, Dina Khalaf, BSc, MSc, MD, Dawn Maze, MDFRCPC,MSc, Caroline J McNamara, MBBS, Aaron D Schimmer, MD PhD, Andre C. Schuh, Hassan Sibai, MBBS, Graham Fletcher, Debbie Valiquette, Kylie Martin, BSc, RN, BSN, Mark D. Minden, Karen W.L. Yee, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 1–2.
https://doi.org/10.1182/blood-2020-138822
Published: 2020
Journal Articles

Fatigue, However Measured, Continues to Refine Prognosis in Higher Risk MDS: An MDS-CAN Study

Free
Irina Amitai, MD, Michelle Geddes, MD, Nancy Zhu, MD, Mary-Margaret Keating, MD FRCPC, Mitchell Sabloff, Grace Christou, MD, Brian Leber, MD, Dina Khalaf, BSc, MSc, MD, Heather A. Leitch, MD, Eve St-Hilaire, MD, Nicholas Finn, MD, April Shamy, MD, Karen W.L. Yee, MD, John M. Storring, MD, Thomas J. Nevill, MD, Robert Delage, MD, Mohamed Elemary, MD, Versha Banerji, MD, Lisa Chodirker, MD, Lee Mozessohn, MD, Anne Parmentier, BA, Mohammed Siddiqui, Alexandre Mamedov, Liying Zhang, PhD, Rena J. Buckstein, MD FRCPC
Journal: Blood
Blood (2020) 136 (Supplement 1): 41–43.
https://doi.org/10.1182/blood-2020-141635
Published: 2020
Journal Articles

Clinical Efficacy and Safety of Oral Decitabine/Cedazuridine in 133 Patients with Myelodysplastic Syndromes (MDS) and Chronic Myelomonocytic Leukemia (CMML)

Free
Michael R. Savona, MD, James K. McCloskey, MD, Elizabeth A. Griffiths, MD, Karen W.L. Yee, MD, Aref Al-Kali, MD, Amer M. Zeidan, MBBS, MHS, H. Joachim Deeg, MD, Prapti A. Patel, MD, Mitchell Sabloff, MSc,MDFRCPC, Mary-Margaret Keating, MD FRCPC, Kim-Hien Dao, DO, PhD, Nancy Zhu, MD, Nashat Gabrail, MD, Salman Fazal, MD, Joseph Maly, MD, Olatoyosi Odenike, MD, Hagop M. Kantarjian, MD, Amy E. DeZern, MD, Casey L. O'Connell, MD, Gail J. Roboz, MD, Lambert Busque, MD, Richard A. Wells, MD DPhil, Harshad Amin, MD, Jasleen K. Randhawa, MD, Brian Leber, MD, Yong Hao, MD PhD, Harold N. Keer, MDPhD, Mohammad Azab, MD, Guillermo Garcia-Manero, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 37–38.
https://doi.org/10.1182/blood-2020-133855
Published: 2020
Journal Articles

RBC-Enhance: A Randomized Pilot Feasibility Trial of Red Cell Transfusion Thresholds in Myelodysplastic Syndromes

Free
Rena J. Buckstein, MD FRCPC, Anca Prica, MD, Brian Leber, MD, Nancy Heddle, MSc, Karen W.L. Yee, MD, Simon J. Stanworth, MD, David Bowen, MD, Lisa Chodirker, MD, Jennifer Gallagher, Anne Parmentier, BA, Liying Zhang, PhD, Alexandre Mamedov, Yulia Lin, MD, Jeannie L Callum, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 3–4.
https://doi.org/10.1182/blood-2020-140165
Published: 2020