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Jose-Mario Capo-Chichi
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Journal Articles

FLT3 is genetically essential for ITD-mutated leukemic stem cells but dispensable for human hematopoietic stem cells

Open Access
Joana L. Araújo, Elvin Wagenblast, Veronique Voisin, Jessica McLeod, Olga I. Gan, Suraj Bansal, Liqing Jin, Amanda Mitchell, Blaise Gratton, Sarah Cutting, Andrea Arruda, Monica Doedens, Anthea Travas, Dennis Kim, Jose-Mario Capo-Chichi, Sagi Abelson, Mark D. Minden, Jean C. Y. Wang, Manuel A. Sobrinho-Simões, Perpétua Pinto-do-Ó, Eric Lechman, John E. Dick
Journal: Blood
Blood (2025) 145 (20): 2361–2373.
https://doi.org/10.1182/blood.2024025886
Published: 2025
Includes: Supplemental data
Journal Articles

Multiparameter Flow Cytometry-Based Measurable Residual Disease Assessment in the Patients with CCAAT Enhancer-Binding Protein a Gene (CEBPA) Mutated Acute Myeloid Leukemia

Free
Swe Mar Linn, Nihar Desai, Steven M. Chan, Andre C. Schuh, Aniket Banker, Marta Beata Davidson, Guillaume Richard-Carpentier, Aron Shimmer, Dawn C. Maze, Karen Yee, Mark D. Minden, Vikas Gupta, Tracy Stockley, Hassan Sibai, Jose-Mario Capo-Chichi, Anne Maria Tierens, Dennis Dong Hwan Kim
Journal: Blood
Blood (2024) 144 (Supplement 1): 1570.
https://doi.org/10.1182/blood-2024-211434
Published: 2024
Journal Articles

Clinical Relevance of NPM1 Quantitative PCR As Standard of Care with Different Cut-Off Values on Treatment Outcomes in NPM1-Mutated Acute Myeloid Leukemia Patients

Free
Donna Zhe Sian Eng, Andre C. Schuh, Aniket Bankar, Marta Beata Davidson, Guillaume Richard-Carpentier, Hassan Sibai, Dawn C. Maze, Karen Yee, Aaron D Schimmer, Vikas Gupta, Tracy Stockley, Jose-Mario Capo-Chichi, Chen Steven, Dennis Dong Hwan Kim
Journal: Blood
Blood (2024) 144 (Supplement 1): 6172.
https://doi.org/10.1182/blood-2024-211783
Published: 2024
Journal Articles

Retrospective Evaluation of BCR::ABL Kinase Domain Mutation Profiles and Treatment Outcomes in Patients with Chronic Myeloid Leukemia to Confirm Clinical Relevance of in Vitro Sensitivity-Based Treatment Switch: Real-World Experience

Free
Maria Agustina Perusini, Eleanore Louise Musick, Filza Gul, May Chiu, Mohammad Alwadi, Noora Obaidallah, Jaeyoon John Kim, Danielle Pyne, Jose-Mario Capo-Chichi, Dennis Dong Hwan Kim
Journal: Blood
Blood (2024) 144 (Supplement 1): 3810.
https://doi.org/10.1182/blood-2024-210449
Published: 2024
Journal Articles

Prognostic Role of Multiparameter Flow Cytometry-Based Measurable Residual Disease Assessment in Acute Myeloid Leukemia Patients with FMS3-like Tyrosine Kinase-3 Internal Tandem Duplication (FLT3-ITD)

Free
Josephine Anne Lucero, Aniket Bankar, Marta Beata Davidson, Guillaume Richard-Carpentier, Aaron D. Schimmer, Andre C. Schuh, Dawn C. Maze, Karen Yee, Mark D. Minden, Steven M. Chan, Jonas Mattsson, Rajat Kumar, Vikas Gupta, Jose-Mario Capo-Chichi, Tracy Stockley, Hassan Sibai, Anne Maria Tierens, Dennis Dong Hwan Kim
Journal: Blood
Blood (2023) 142 (Supplement 1): 1595.
https://doi.org/10.1182/blood-2023-190694
Published: 2023
Journal Articles

Real World Experience of FLT3-Inhibitor Post-Transplant Maintenance with Sorafenib Demonstrating Superior Overall- and Relapse Free Survival Following Allogeneic Hematopoietic Stem Cell Transplantation in FLT3-ITD Mutated Acute Myeloid Leukemia

Free
Yomna Eissa, Eshrak Al-Shaibani, Igor Novitzky-Basso, Ivan Pasic, Wilson Lam, Jose-Mario Capo-chichi, Arjun D. Law, Fotios Michelis, Auro Viswabandya, Armin Gerbitz, Rajat Kumar, Jonas Mattsson, Dennis D. H. Kim
Journal: Blood
Blood (2023) 142 (Supplement 1): 3589.
https://doi.org/10.1182/blood-2023-185951
Published: 2023
Journal Articles

Multiparameter Flow Cytometry-Based Residual Disease Analysis Identifies Intermediate-Risk AML Patients Who May Benefit from Allogeneic Hematopoietic Stem Cell Transplantation

Free
Josephine Anne Lucero, Anne Tierens, Muhned Alhumaid, Jose-Mario Capo-Chichi, Tracy L. Stockley, Vikas Gupta, Steven M. Chan, Andre C. Schuh, Mark D. Minden, Jonas Mattsson, Rajat Kumar, Hassan Sibai, Dennis Dong Hwan Kim
Journal: Blood
Blood (2022) 140 (Supplement 1): 11797–11798.
https://doi.org/10.1182/blood-2022-168260
Published: 2022
Journal Articles

Single-Cell Proteogenomic Sequencing Allows Early Detection of Relapse Clone with CN-LOH at FLT3 -ITD Locus from Initial Diagnosis in AML

Free
Taehyung Kim, Hyewon Lee, Jose-Mario Capo-Chichi, Myung Hee Chang, Young Seok Yoo, Gurbaksh Basi, Troy Ketela, Adam C. Smith, Anne Tierens, Mark D. Minden, Zhaolei Zhang, Dennis Dong Hwan Kim
Journal: Blood
Blood (2021) 138 (Supplement 1): 3428.
https://doi.org/10.1182/blood-2021-146572
Published: 2021
Journal Articles

Clinical Features and Long-Term Outcomes in a Molecularly-Annotated Cohort of Adolescents and Young Adults with Myeloproliferative Neoplasms

Free
James T. England, Rouslan Kotchetkov, Hubert Tsui, Jose-Mario Capo-Chichi, Andrea Arruda, Sarah Malik, Verna Cheung, Taylor Nye, Hassan Sibai, Vikas Gupta, Dawn Maze
Journal: Blood
Blood (2021) 138 (Supplement 1): 3648.
https://doi.org/10.1182/blood-2021-148706
Published: 2021
Journal Articles

Clinical Significance of Emergent Leukocytosis in Patients with Myelofibrosis Receiving JAK Inhibitor Therapy

Free
Radovan Vasic, MD MHS, Yuliang Shi, Andrea Arruda, MSc, Sarah Malik, Jaime Claudio, PhD, Jose-Mario Capo-Chichi, PhD, Aniket Bankar, MBBS, MD DM, Hassan Sibai, MBBS, Dawn Maze, MDFRCPC,MSc, James A. Kennedy, MDPhD, Wei Xu, PhD, Vikas Gupta, MD FRCP, FRCPath
Journal: Blood
Blood (2020) 136 (Supplement 1): 22.
https://doi.org/10.1182/blood-2020-139936
Published: 2020
Journal Articles

Prognostic Impact of a Composite Genetic Profile Defined By Cytogenetics and Next Generation Sequencing at Diagnosis on Treatment Outcomes Following Allogeneic Hematopoietic Stem Cell Transplantation in Acute Myeloid Leukemia

Free
Georgina S. Daher-Reyes, MD, TaeHyung Kim, MSc, Kyoung Ha Kim, MD PhD, Jae-Sook Ahn, MD PhD, Tracy L. Stockley, PhD FCCMG, FACMG, Jose Mario Capo-Chichi, PhD FACMG, Zeyad Al-Shaibani, MD, Arjun Law, MDDM, Wilson Lam, MD, Fotios V. Michelis, MD PhD, Auro Viswabandya, MDDM, Jeffrey H. Lipton, MD PhD, Rajat Kumar, MD, Jonas Mattsson, MD, Aaron D Schimmer, MD PhD, Caroline J McNamara, MBBS, Tracy Murphy, MDFRCP,FRCPath, Dawn Maze, MDFRCPC,MSc, Vikas Gupta, MD FRCP, FRCPath, Hassan Sibai, MBBS, Steven M Chan, MD PhD, Karen W.L. Yee, MD, Mark D. Minden, MD PhD, Zhaolei Zhang, PhD, Andre C. Schuh, MD, Dennis Dong Hwan Kim, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3317.
https://doi.org/10.1182/blood-2019-125780
Published: 2019
Journal Articles

Impact of Genetic Profile on Clinical Outcomes in Adults ≥60 with AML: The Princess Margaret Cancer Centre Experience

Free
Georgina S Daher-Reyes, MD, Caroline J McNamara, MBBS, Manjula Maganti, MSc, Tracy L. Stockley, PhD FCCMG, FACMG, Jose Mario Capo-Chichi, PhD FACMG, Reem Abdulrahman Alkharras, Andrea Arruda, Jaime Claudio, Steven M Chan, MD PhD, Aaron D Schimmer, MD PhD, Mark D. Minden, MD PhD, Hassan Sibai, MBBS, Karen W.L. Yee, MD, Vikas Gupta, MD FRCP, FRCPath, Suzanne Kamel-Reid, BA, MA, PhD FACMG, Dawn Maze, MD FRCPC, MSc, Andre Schuh
Journal: Blood
Blood (2018) 132 (Supplement 1): 2666.
https://doi.org/10.1182/blood-2018-99-118938
Published: 2018