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Jessica McLeod
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Journal Articles

Adaptation to ex vivo culture reduces human hematopoietic stem cell activity independently of the cell cycle

Carys S. Johnson, Matthew Williams, Kendig Sham, Serena Belluschi, Wenjuan Ma, Xiaonan Wang, Winnie W. Y. Lau, Kerstin B. Kaufmann, Gabriela Krivdova, Emily F. Calderbank, Nicole Mende, Jessica McLeod, Giovanna Mantica, Juan Li, Charlotte Grey-Wilson, Michael Drakopoulos, Shaaezmeen Basheer, Shubhankar Sinha, Evangelia Diamanti, Christina Basford, Nicola K. Wilson, Steven J. Howe, John E. Dick, Berthold Göttgens, Anthony R. Green, Natalie Francis, Elisa Laurenti
Journal: Blood
Blood (2024) 144 (7): 729–741.
https://doi.org/10.1182/blood.2023021426
Published: 2024
Includes: Supplemental data
Journal Articles

Uncovering Distinct Metabolic Properties of Relapse and Relapse-Fated Clones in B-Cell Acute Lymphoblastic Leukemia

Sabrina A Smith, Laura Garcia Prat, Mohsen Hosseini, Liqing Jin, Nathan Mbong, Monica Doedens, Jessica McLeod, Julie A. Reisz, Rebecca Wilkerson, Angelo D'Alessandro, Steven M. Chan, Courtney L Jones, John E. Dick
Journal: Blood
Blood (2022) 140 (Supplement 1): 5905–5906.
https://doi.org/10.1182/blood-2022-162652
Published: 2022
Journal Articles

Sirpαfc Treatment Targets Human Acute Myeloid Leukemia Stem Cells

Oleksandr Galkin, PhD, Jessica McLeod, BSc, James A Kennedy, MD PhD, Liqing Jin, MD, Nathan Mbong, Mark Wong, PhD, Bob Uger, PhD, Mark D. Minden, MD PhD, Jayne S Danska, PhD, Jean C.Y. Wang, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3906.
https://doi.org/10.1182/blood-2019-131018
Published: 2019
Journal Articles

Genetic Analysis of B-Cell Acute Lymphoblastic Leukemia Dissemination to the Central Nervous System Identifies Clonal Selection and Therapeutic Vulnerability

Robert Vanner, MD PhD, Stephanie M. Dobson, PhD, Ildiko Grandal, MSc, Olga I. Gan, PhD, Jessica McLeod, BSc, James Kennedy, MD PhD, Veronique Voisin, PhD, Cynthia Guidos, PhD, Jayne S. Danska, PhD, Esme Waanders, PhD, Mark D. Minden, MD PhD, Charles G. Mullighan, MBBS, MD, John E. Dick, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1542.
https://doi.org/10.1182/blood-2018-99-115191
Published: 2018
Journal Articles

Relapse-Initiating Clones Preexisting at Diagnosis in B- Cell Acute Lymphoblastic Leukemia Help Predict Molecular Pathways of Relapse

Laura Garcia Prat, Stephanie M. Dobson, PhD, Michelle Chan-Seng-Yue, Robert Vanner, MD PhD, Alex Murison, Jeffery Wintersinger, Esme Waanders, PhD, Olga I. Gan, PhD, Jessica McLeod, BSc, Debbie Payne-Turner, Michael Edmonson, Zhaohui Gu, PhD, Xiaotu Ma, Yiping Fan, Pankaj Gupta, Michael Rusch, BS, Ying Shao, John Easton, PhD, Jinghui Zhang, Mark D. Minden, MD PhD, Quaid Morris, Mathieu Lupien, Charles G. Mullighan, MBBS, MD, John E. Dick, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 915.
https://doi.org/10.1182/blood-2018-99-118998
Published: 2018
Journal Articles

Isolation of CD34 − and CD34 + Leukemia Stem Cells from Acute Myeloid Leukemia Blasts Using CD200

Jenny M. Ho, MD, Stephanie M. Dobson, PhD, Jessica McLeod, BSc, Veronique Voisin, PhD, Alex Murison, James Kennedy, MD PhD, Sasan Zandi, MD PhD, Kolja Eppert, MSc, PhD, Mark D. Minden, MD PhD, Mathieu Lupien, John E. Dick, PhD, Jean C.Y. Wang, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2790.
https://doi.org/10.1182/blood-2018-99-119318
Published: 2018
Journal Articles

A Stemness Screen Reveals C3ORF54/INKA1 As a Gate-Keeper of Human Stem Cell Latency

Kerstin B. Kaufmann, PhD, Laura Garcia Prat, Shin-Ichiro Takayanagi, PhD, Jessica McLeod, BSc, Olga I. Gan, Kristele Pan, Stephanie Zhi-Juan Xie, PhD, John E. Dick, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 325.
https://doi.org/10.1182/blood-2018-99-115065
Published: 2018
Journal Articles

Linking Subclonal Genetic Diversity with Functional Heterogeneity Identifies Diagnosis Subclones Destined to Relapse

Stephanie M. Dobson, Esme Waanders, PhD, Robert Vanner, PhD, Olga I Gan, PhD, Jessica McLeod, Ildiko Grandal, MSc, Debbie Payne-Turner, BA, Michael Edmonson, PhD, Zhaohui Gu, PhD, Xiaotu Ma, PhD, Yiping Fan, Sagi Abelson, PhD, Pankaj Gupta, Michael Rusch, Ying Shao, Lei Shi, PhD, Stanley Pounds, PhD, Scott Olsen, Geoffrey A. Neale, PhD, John Easton, PhD, Cynthia J. Guidos, PhD, Jayne S. Danska, PhD, Jinghui Zhang, PhD, Mark D. Minden, MD PhD, Charles G. Mullighan, MBBS(Hons), MSc, MD, John E. Dick, PhD
Journal: Blood
Blood (2016) 128 (22): 605.
https://doi.org/10.1182/blood.V128.22.605.605
Published: 2016
Journal Articles

CD200 Is a Marker of LSC Activity in Acute Myeloid Leukemia

Jenny M. Ho, MD, Stephanie M. Dobson, Jessica McLeod, Liqing Jin, MD PhD, Stanley W.K. Ng, MSc, Amanda Mitchell, PhD, Liran I. Shlush, MD PhD, Sasan Zandi, MD PhD, Kolja Eppert, PhD, Mark D. Minden, MD PhD, John E. Dick, PhD, Jean C.Y. Wang, MD PhD
Journal: Blood
Blood (2016) 128 (22): 1705.
https://doi.org/10.1182/blood.V128.22.1705.1705
Published: 2016
Journal Articles

The Human Blood Hierarchy Is Shaped By Distinct Progenitor Lineages Across Development

Sasan Zandi, MDPhD, Faiyaz Notta, John E. Dick, PhD, Naoya Takayama, Stephanie M Dobson, MSc, Olga I Gan, PhD, Gavin Wilson, Kerstin Kaufmann, Jessica McLeod, Elisa Laurenti, PhD, Cyrille Dunant, Mcpherson John, Lincoln Stein, Yigal Dror, MD FRCP(C)
Journal: Blood
Blood (2015) 126 (23): 2360.
https://doi.org/10.1182/blood.V126.23.2360.2360
Published: 2015
Journal Articles

Engraftment Patterns in NOD. SCID Mice Predict Outcome in Human AML

James A. Kennedy, MDPhD, Amanda Mitchell, PhD, Weihsu Claire Chen, PhD, Liqing Jin, MD, Stanley Wai-Kwong Ng, BASc, Liran I. Shlush, MDPhD, Sasan Zandi, MDPhD, Jessica McLeod, BSc, Andreea C. Popescu, BSc, Nathan Mbong, BSc, Andrea Arruda, MSc, Mark D Minden, MDPhD, John E. Dick, PhD, Jean C.Y. Wang, MDPhD
Journal: Blood
Blood (2014) 124 (21): 16.
https://doi.org/10.1182/blood.V124.21.16.16
Published: 2014
Journal Articles

Functional and Phenotypic Characterization Of Acute Myeloid Leukemia By Analysis Of Diagnostic/Relapse Paired Samples

Jenny M. Ho, MD, Liran I. Shlush, MD, PhD, Amanda Mitchell, PhD, Rene Marke, Jessica McLeod, Mark D. Minden, MD PhD, John E. Dick, PhD, Jean C.Y. Wang, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 2595.
https://doi.org/10.1182/blood.V122.21.2595.2595
Published: 2013
Journal Articles

Defining Functional Heterogeneity In Acute Lymphoblastic Leukemia

Stephanie M. Dobson, BSc, Esmé Waanders, PhD, Jessica McLeod, Ildiko Grandal, Olga I. Gan, PhD, Faiyaz Notta, PhD, Jessica Loo-Young-Kee, Mark D. Minden, MD PhD, Cynthia J. Guidos, PhD, Jayne S. Danska, PhD, Charles G. Mullighan, MBBS, MSc, MD, FRACP, FRCPA, John E. Dick, PhD
Journal: Blood
Blood (2013) 122 (21): 1365.
https://doi.org/10.1182/blood.V122.21.1365.1365
Published: 2013
Journal Articles

Leukemic Engraftment In NOD. SCID Mice Is Correlated With Clinical Parameters and Predicts Outcome In Human AML

James A. Kennedy, MD PhD, Amanda Mitchell, PhD, Weihsu Claire Chen, PhD, Jessica McLeod, Andreea C. Popescu, BSc, Andrea Arruda, MSc, Mark D. Minden, MD PhD, John E. Dick, PhD, Jean C.Y. Wang, MD PhD
Journal: Blood
Blood (2013) 122 (21): 50.
https://doi.org/10.1182/blood.V122.21.50.50
Published: 2013