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Alex Murison
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Journal Articles

A Novel Role for PLK1 in Leukemia Stem Cell Function in Acute Myeloid Leukemia

Qiang Liu, Alex Murison, Andy G.X. Zeng, Changjiang Xu, Veronique Voisin, Faith Yeung, Amit Subedi, Steven M. Chan, Brian Raught, Gary D Bader, John E. Dick, Jean C.Y. Wang
Journal: Blood
Blood (2022) 140 (Supplement 1): 5920–5921.
https://doi.org/10.1182/blood-2022-169732
Published: 2022
Journal Articles

KDM6 Demethylases Integrate DNA Repair Gene Regulation: Loss of KDM6A Sensitizes AML to PARP Inhibition and Potentiates with BCL2 Blockade

Liberalis Debraj Boila, Liqing Jin, Alex Murison, Subham K. Bandyopadhyay, Subhadeep Ghosh, Siva Sai Naga Anurag Muddineni, Andy G.X. Zeng, Sayantani Sinha, Shankha Subhra Chatterjee, Mayukh Biswas, Nathan Mbong, Olga I. Gan, Andrea Arruda, Wasim Shaikh, Anwesha Bose, Satyaki Bhowmik, Sayan Chakraborty, James A. Kennedy, Amanda Mitchell, Eric R. Lechman, Debasis Banerjee, Michael Milyavsky, Mark D. Minden, John E. Dick, Amitava Sengupta
Journal: Blood
Blood (2021) 138 (Supplement 1): 25.
https://doi.org/10.1182/blood-2021-145491
Published: 2021
Journal Articles

A Human Model of Down Syndrome Associated Leukemia Reveals Different Cell of Origins for Initiation and Progression

Elvin Wagenblast, PhD, Joana Araújo, MD, Olga I. Gan, PhD, Sarah K Cutting, Alex Murison, Jessica L. McLeod, Gabriela Krivdova, BSc, Maria Azkanaz, Sabrina A Smith, Johann K Hitzler, MD, John E. Dick, PhD FRS, Eric R Lechman, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 11–12.
https://doi.org/10.1182/blood-2020-135867
Published: 2020
Journal Articles

Dichotomous Regulation of Lysosomes By MYC and Tfeb Controls Hematopoietic Stem Cell Fate

Laura Garcia Prat, PhD BSc, MSc, Kerstin B Kaufmann, PhD, Florin Schneiter, Veronique Voisin, PhD, Alex Murison, Michelle Chan-Seng-Yue, Olga I. Gan, PhD, Jessica L. McLeod, Michelle Shoong, Kristele Pan, Kinam Gupta, Shin-Ichiro Takayanagi, PhD, Elvin Wagenblast, PhD, Weijia Wang, Timm Schroeder, PhD, Stephanie Zhi-Juan Xie, PhD, John E. Dick, PhD FRS
Journal: Blood
Blood (2020) 136 (Supplement 1): 34.
https://doi.org/10.1182/blood-2020-142671
Published: 2020
Journal Articles

Identification of Gene Regulatory Networks Governing Stemness Properties of Human HSC and LSC

Stanley W.K. Ng, Stephanie Zhi-Juan Xie, PhD, Elvin Wagenblast, PhD, Naoya Takayama, MD PhD, Liqing Jin, MD, Nathan Mbong, Alex Murison, Schoof E Erwin, Amanda Mitchell, PhD, Peter Van Galen, PhD, Mathieu Lupien, PhD, Mark D. Minden, MD PhD, Jean C.Y. Wang, MD PhD, Peter W. Zandstra, PhD, John E. Dick
Journal: Blood
Blood (2018) 132 (Supplement 1): 3832.
https://doi.org/10.1182/blood-2018-99-114314
Published: 2018
Journal Articles

Isolation of CD34 − and CD34 + Leukemia Stem Cells from Acute Myeloid Leukemia Blasts Using CD200

Jenny M. Ho, MD, Stephanie M. Dobson, PhD, Jessica McLeod, BSc, Veronique Voisin, PhD, Alex Murison, James Kennedy, MD PhD, Sasan Zandi, MD PhD, Kolja Eppert, MSc, PhD, Mark D. Minden, MD PhD, Mathieu Lupien, John E. Dick, PhD, Jean C.Y. Wang, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2790.
https://doi.org/10.1182/blood-2018-99-119318
Published: 2018
Journal Articles

Relapse-Initiating Clones Preexisting at Diagnosis in B- Cell Acute Lymphoblastic Leukemia Help Predict Molecular Pathways of Relapse

Laura Garcia Prat, Stephanie M. Dobson, PhD, Michelle Chan-Seng-Yue, Robert Vanner, MD PhD, Alex Murison, Jeffery Wintersinger, Esme Waanders, PhD, Olga I. Gan, PhD, Jessica McLeod, BSc, Debbie Payne-Turner, Michael Edmonson, Zhaohui Gu, PhD, Xiaotu Ma, Yiping Fan, Pankaj Gupta, Michael Rusch, BS, Ying Shao, John Easton, PhD, Jinghui Zhang, Mark D. Minden, MD PhD, Quaid Morris, Mathieu Lupien, Charles G. Mullighan, MBBS, MD, John E. Dick, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 915.
https://doi.org/10.1182/blood-2018-99-118998
Published: 2018
Journal Articles

Microrna-130a Regulates Hematopoietic Stem Cell Self-Renewal By Repressing Chromatin Modifiers and Shaping the Accessible Chromatin Landscape

Gabriela Krivdova, BSc, MSc, Schoof E Erwin, Veronique Voisin, PhD, Alex Murison, Karin G. Hermans, Laura Garcia Prat, Olga I. Gan, Elvin Wagenblast, PhD, Aaron Trotman-Grant, Eric R. Lechman,, PhD MSC, Mark D. Minden, MD PhD, John E. Dick, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3824.
https://doi.org/10.1182/blood-2018-99-116866
Published: 2018
Journal Articles

Sphingolipid Perturbation Activates Proteostasis Programs to Govern Human Hematopoietic Stem Cell Self-Renewal

Stephanie Zhi-Juan Xie, PhD, Laura Garcia Prat, Veronique Voisin, PhD, Alex Murison, Olga I. Gan, Robin Ferrari, Naoya Takayama, MD PhD, Kerstin B. Kaufmann, PhD, Ishita Patel, Esther Lee, Gareth Holmes, Tiago Medina, PhD, Aditi Vedi, Chiara Luberto, PhD, Gary D Bader, Elisa Laurenti, PhD, Mathieu Lupien, John E. Dick, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 170.
https://doi.org/10.1182/blood-2018-170
Published: 2018
Journal Articles

A Cluster of Enhancer Modules Directs Differential Myc Expression Along the Normal and Leukemic Hematopoietic Stem Cell Hierarchies

Carsten Bahr, MSc, Lisa von Paleske, PhD, Veli Vural Uslu, PhD, Silvia Remeseiro, PhD, Naoya Takayama, MD PhD, Stanley W.K. Ng, Alex Murison, PhD, Katja Langenfeld, Massimo Petretich, PhD, Roberta Scognamiglio, PhD, Petra Zeisberger, Amelie Benk, PhD, Ido Amit, PhD, Peter W. Zandstra, PhD, John E. Dick, PhD, Mathieu Lupien, PhD, Andreas Trumpp, Prof, PhD, Francois Spitz, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1150.
https://doi.org/10.1182/blood.V130.Suppl_1.1150.1150
Published: 2017
Journal Articles

Chromatin Accessibility Identifies CTCF As a Gatekeeper of Stemness Functions in Human Hematopoietic Development

Naoya Takayama, MD PhD, Alex Murison, PhD, Shin-ichiro Takayanagi, PhD, Sasan Zandi, MD PhD, Nadia Penrod, PhD, Amanda Mitchel, James A. Kennedy, MD PhD, Stanley W.K. Ng, MSc, Stephanie Zhi-Juan Xie, PhD, Mark D. Minden, MD PhD, John E. Dick, PhD, Mathieu Lupien, PhD
Journal: Blood
Blood (2016) 128 (22): 3873.
https://doi.org/10.1182/blood.V128.22.3873.3873
Published: 2016
Journal Articles

Spatiotemporal Analysis of Intraclonal Heterogeneity in Multiple Myeloma: Unravelling the Impact of Treatment and the Propagating Capacity of Subclones Using Whole Exome Sequencing

Lorenzo Melchor, PhD, John R Jones, MD, Oleg Lenive, Erich Allen Peterson, PhD BS, MS, Annamaria Brioli, MD PhD, Alex Murison, PhD, Christopher P Wardell, PhD, Martin F Kaiser, Paula Proszek, Eileen Mary Boyle, MD PhD, Dil B Begum, Charlotte Pawlyn, MB BChir, David C Johnson, PhD, Inmaculada Rapado, David A Cairns, Walter M Gregory, Roger G Owen, Graham H Jackson, MD PhD, Mark T Drayson, MD PhD, Faith E Davies, MD, Joaquín Martínez-López, MD PhD, Richard S Houlston, MDPhDFRCP, Mel Greaves, FRS, Brian A Walker, PhD, Gareth J Morgan, MD PhD
Journal: Blood
Blood (2015) 126 (23): 371.
https://doi.org/10.1182/blood.V126.23.371.371
Published: 2015
Journal Articles

Coexistent hyperdiploidy does not abrogate poor prognosis in myeloma with adverse cytogenetics and may precede IGH translocations

Charlotte Pawlyn, Lorenzo Melchor, Alex Murison, Christopher P. Wardell, Annamaria Brioli, Eileen M. Boyle, Martin F. Kaiser, Brian A. Walker, Dil B. Begum, Nasrin B. Dahir, Paula Proszek, Walter M. Gregory, Mark T. Drayson, Graham H. Jackson, Fiona M. Ross, Faith E. Davies, Gareth J. Morgan
Journal: Blood
Blood (2015) 125 (5): 831–840.
https://doi.org/10.1182/blood-2014-07-584268
Published: 2015
Includes: Supplemental data