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Journal Articles

Genomic determinants of response and resistance to inotuzumab ozogamicin in B-cell ALL

Blood (2024) 144 (1): 61–73.

https://doi.org/10.1182/blood.2024023930

Published: 2024

Includes: Supplemental data

Journal Articles

Gene Expression Machine Learning Models Classify Pediatric AML Subtypes with High Performance

Krish Shah, Jing Ma, Mohamed Djekidel, Guangchun Song, Masayuki Umeda, Yiping Fan, Gang Wu, Jeffery Klco

Blood (2023) 142 (Supplement 1): 1570.

https://doi.org/10.1182/blood-2023-189450

Published: 2023

Journal Articles

The genomic landscape of acute lymphoblastic leukemia with intrachromosomal amplification of chromosome 21

Blood (2023) 142 (8): 711–723.

https://doi.org/10.1182/blood.2022019094

Published: 2023

Includes: Supplemental data

Journal Articles

Genetic and Epigenetic Cis -Regulatory Disruptions Impacting the Canonical Wnt Signaling Repressor TLE1 Gene Promote Glucocorticoid Resistance in Childhood Acute Lymphoblastic Leukemia

Brennan P. Bergeron, Jonathan D. Diedrich, Yang Zhang, Kelly R. Barnett, Qian Dong, Daniel Ferguson, Robert J Autry, Wenjian Yang, Baranda S Hansen, Colton A Smith, Kristine R. Crews, Yiping Fan, Ching-Hon Pui, Shondra Miller, Mary V. Relling, Jun J. Yang, Chunliang Li, William E. Evans, Daniel Savic

Blood (2022) 140 (Supplement 1): 8838–8839.

https://doi.org/10.1182/blood-2022-166973

Published: 2022

Journal Articles

Comprehensive Genome Characterization of Childhood T-ALL Links Oncogene Activation Mechanism and Subtypes to Prognosis

Blood (2022) 140 (Supplement 1): 1727–1729.

https://doi.org/10.1182/blood-2022-167157

Published: 2022

Journal Articles

CD19-CAR T Cells Develop Exhaustion Epigenetic Programs during a Clinical Response

Caitlin C. Zebley, Charmaine Brown, Tian Mi, Yiping Fan, Shanta Alli, Shannon Boi, Giovanni Galletti, Enrico Lugli, Deanna Langfitt, Jean-Yves Metais, Timothy Lockey, Michael M Meagher, Brandon M Triplett, Aimee C Talleur, Stephen Gottschalk, Benjamin Youngblood

Blood (2021) 138 (Supplement 1): 2782.

https://doi.org/10.1182/blood-2021-151177

Published: 2021

Journal Articles

Mapping the Glucocorticoid Gene Regulatory Network and Alterations That Contribute to Steroid Resistance in Childhood Acute Lymphoblastic Leukemia

Brennan P. Bergeron, Jonathan Diedrich, Yang Zhang, Qian Dong, Daniel Ferguson, Robert J Autry, Wenjian Yang, Baranda S Hansen, Kristine R. Crews, Ching-Hon Pui, Yiping Fan, Shondra M. Pruett-Miller, Mary V. Relling, Jun J. Yang, Chunliang Li, William E. Evans, Daniel Savic

Blood (2021) 138 (Supplement 1): 674.

https://doi.org/10.1182/blood-2021-153002

Published: 2021

Journal Articles

Regnase-1 suppresses TCF-1 + precursor exhausted T-cell formation to limit CAR–T-cell responses against ALL

Wenting Zheng, Jun Wei, Caitlin C. Zebley, Lindsay L. Jones, Yogesh Dhungana, Yong-Dong Wang, Jayadev Mavuluri, Lingyun Long, Yiping Fan, Ben Youngblood, Hongbo Chi, Terrence L. Geiger

Blood (2021) 138 (2): 122–135.

https://doi.org/10.1182/blood.2020009309

Published: 2021

Includes: Supplemental data

Journal Articles

FBXO11-mediated proteolysis of BAHD1 relieves PRC2-dependent transcriptional repression in erythropoiesis

Blood (2021) 137 (2): 155–167.

https://doi.org/10.1182/blood.2020007809

Published: 2021

Includes: Supplemental data

Journal Articles

The Genomic Landscape of Childhood Acute Lymphoblastic Leukemia

Kathryn G. Roberts, PhD, Samuel W. Brady, PhD, Zhaohui Gu, PhD, Lei Shi, PhD, Stanley Pounds, PhD, Deqing Pei, MS, Cheng Cheng, PhD, Yunfeng Dai, PhD, Meenakshi Devidas, PhD, Chunxu Qu, PhD, Ashley Hill, BS, Xiaotu Ma, Lei Wei, PhD, Sasi Arunachalam, PhD, Kohei Hagiwara, MD, Yangling Liu, Diane Flasch, Yu Liu, PhD, Matthew Parker, PhD, Xiaolong Chen, PhD, Yongjin Li, PhD, Yiping Fan, PhD, Robert Michael, PhD, Michael Rusch, BS, Mark Wilkinson, Scott Foy, PhD, Dale Hedges, PhD, Scott Newman, PhD, Xin Zhou, PhD, Jian Wang, Shalini C. Reshmi, PhD, Julie M. Gastier-Foster, PhD, Patee Gesuwan, Malcolm A Smith, MD PhD, Daniela S. Gerhard, PhD, Naomi Winick, MD, Andrew J. Carroll, PhD, Nyla A. Heerema, PhD, Richard C. Harvey, PhD, Cheryl L. Willman, MD, Eric Larsen, MD, Elizabeth A. Raetz, MD, Michael J. Borowitz, MD PhD, Brent L Wood, MD PhD, William L. Carroll, MD, Patrick A. Zweidler-McKay, MD PhD, Karen R. Rabin, MD PhD, Leonard A. Mattano, MD, Kelly Maloney, MD, Stuart S. Winter, MD, Michael J. Burke, MD, Wanda L. Salzer, MD, Kimberly P. Dunsmore, Anne Angiolillo, MD, Kristine R Crews, PharmD, James R. Downing, MD, Sima Jeha, MD, William E. Evans, PharmD, Ching-Hon Pui, MD, Jun J. Yang, PhD, Mary V. Relling, PharmD, Stephen P. Hunger, MD, Mignon L. Loh, MD, Jinghui Zhang, PhD, Charles G. Mullighan, MBBS, MD

Blood (2019) 134 (Supplement_1): 649.

https://doi.org/10.1182/blood-2019-124881

Published: 2019

Journal Articles

Engineering Naturally Occurring CD7 Negative Cells for the Immunotherapy of CD7 Positive Leukemia

Abdullah Freiwan, MSc, Abishek Vaidya, MS, Caitlin Zebley, MD, Yiping Fan, PhD, Deanna Langfitt, PhD, Benjamin Youngblood, PhD, Maksim Mamonkin, PhD, Stephen Gottschalk, MD, Mireya Paulina Velasquez, MD

Blood (2019) 134 (Supplement_1): 868.

https://doi.org/10.1182/blood-2019-124903

Published: 2019

Journal Articles

Relapse-Initiating Clones Preexisting at Diagnosis in B- Cell Acute Lymphoblastic Leukemia Help Predict Molecular Pathways of Relapse

Blood (2018) 132 (Supplement 1): 915.

https://doi.org/10.1182/blood-2018-99-118998

Published: 2018

Journal Articles

CREBBP Histone Acetyltransferase Domain Mutations Result in Dexamethasone Resistance in B-Progenitor Acute Lymphoblastic Leukemia

Yunchao Chang, PhD, David W. Woessner, PhD MS, Wenwei Lin, PhD, Taosheng Chen, PhD, Beisi Xu, PhD, Yiping Fan, PhD, Haiyan Tan, PhD, Junmin Peng, PhD, Lawryn Kasper, PhD, Michelle L. Churchman, PhD, Mignon L. Loh, MD, Stephen P. Hunger, MD, Aman Seth, PhD, Karen Gascoigne, PhD, Paul K Brindle, PhD, Charles G. Mullighan, MBBS, MD

Blood (2017) 130 (Supplement 1): 560.

https://doi.org/10.1182/blood.V130.Suppl_1.560.560

Published: 2017

Journal Articles

Linking Subclonal Genetic Diversity with Functional Heterogeneity Identifies Diagnosis Subclones Destined to Relapse

Blood (2016) 128 (22): 605.

https://doi.org/10.1182/blood.V128.22.605.605

Published: 2016

Journal Articles

Outcome of children with hypodiploid ALL treated with risk-directed therapy based on MRD levels

Blood (2015) 126 (26): 2896–2899.

https://doi.org/10.1182/blood-2015-09-671131

Published: 2015

Journal Articles

Genomic Landscape of Relapsed Acute Lymphoblastic Leukemia

Blood (2015) 126 (23): 692.

https://doi.org/10.1182/blood.V126.23.692.692

Published: 2015

Journal Articles

Inherited GATA3 genetic Variants Are Associated With Childhood BCR-ABL1 -Like Acute Lymphoblastic Leukemia and Increased Risk Of Relapse

Virginia Perez-Andreu, MD PhD, Kathryn G. Roberts, PhD, Richard C. Harvey, PhD, Wenjian Yang, PhD, Cheng Cheng, PhD, Deqing Pei, MS, Heng Xu, PhD, Julie Gastier-Fostier, PhD, Shuyu E, PhD, Joshua Yew-Suang Lim, I-Ming L. Chen, Yiping Fan, PhD, Meenakshi Devidas, PhD, Michael J. Borowitz, MD, PhD, Colton Smith, PhD, Geoffrey A. Neale, PhD, Esteban Gonzalez Burchard, MD, MPH, Dara G Torgerson, PhD, Federico Antillon, MD, Cesar Rolando, B.S., Naomi J. Winick, MD, Bruce Camitta, MD, Elizabeth A. Raetz, MD, Brent L. Wood, MD, PhD, Feng Yue, PhD, William L. Carroll, MD, Eric C. Larsen, MD, William Paul Bowman, MD, Mignon L. Loh, MD, Michael Dean, PhD, Deepa Bhojwani, MD, Ching-Hon Pui, MD, William E. Evans, PharmD, Mary V. Relling, PharmD, Stephen P. Hunger, MD, Cheryl L. Willman, MD, Charles G. Mullighan, MBBS, MSc, MD, FRACP, FRCPA, Jun J. Yang, PhD

Blood (2013) 122 (21): 617.

https://doi.org/10.1182/blood.V122.21.617.617

Published: 2013

Journal Articles

Genome-Wide Association Analyses Identify Susceptibility Loci For Vincristine-Induced Peripheral Neuropathy In Children With Acute Lymphoblastic Leukemia

Blood (2013) 122 (21): 618.

https://doi.org/10.1182/blood.V122.21.618.618

Published: 2013

Journal Articles

Genome-wide study of methotrexate clearance replicates SLCO1B1

Laura B. Ramsey, John C. Panetta, Colton Smith, Wenjian Yang, Yiping Fan, Naomi J. Winick, Paul L. Martin, Cheng Cheng, Meenakshi Devidas, Ching-Hon Pui, William E. Evans, Stephen P. Hunger, Mignon Loh, Mary V. Relling

Blood (2013) 121 (6): 898–904.

https://doi.org/10.1182/blood-2012-08-452839

Published: 2013

Includes: Supplemental data

Journal Articles

A Genome-Wide Analysis of Variants Influencing Methotrexate Clearance Replicates SLCO1B1 .

Laura B. Ramsey, PhD, John C Panetta, PhD, Colton Smith, PhD, Wenjian Yang, PhD, Yiping Fan, PhD, Naomi Winick, MD, Paul L. Martin, MD, PhD, Cheng Cheng, PhD, Meenakshi Devidas, PhD, Ching-Hon Pui, MD, William E. Evans, PharmD, Stephen P. Hunger, MD, Mignon L. Loh, MD, Mary V. Relling, PharmD

Blood (2012) 120 (21): 2466.

https://doi.org/10.1182/blood.V120.21.2466.2466

Published: 2012

NARROW

Genomic determinants of response and resistance to inotuzumab ozogamicin in B-cell ALL

Gene Expression Machine Learning Models Classify Pediatric AML Subtypes with High Performance

The genomic landscape of acute lymphoblastic leukemia with intrachromosomal amplification of chromosome 21

Genetic and Epigenetic Cis -Regulatory Disruptions Impacting the Canonical Wnt Signaling Repressor TLE1 Gene Promote Glucocorticoid Resistance in Childhood Acute Lymphoblastic Leukemia

Comprehensive Genome Characterization of Childhood T-ALL Links Oncogene Activation Mechanism and Subtypes to Prognosis

CD19-CAR T Cells Develop Exhaustion Epigenetic Programs during a Clinical Response

Mapping the Glucocorticoid Gene Regulatory Network and Alterations That Contribute to Steroid Resistance in Childhood Acute Lymphoblastic Leukemia

Regnase-1 suppresses TCF-1 + precursor exhausted T-cell formation to limit CAR–T-cell responses against ALL

FBXO11-mediated proteolysis of BAHD1 relieves PRC2-dependent transcriptional repression in erythropoiesis

The Genomic Landscape of Childhood Acute Lymphoblastic Leukemia

Engineering Naturally Occurring CD7 Negative Cells for the Immunotherapy of CD7 Positive Leukemia

Relapse-Initiating Clones Preexisting at Diagnosis in B- Cell Acute Lymphoblastic Leukemia Help Predict Molecular Pathways of Relapse

CREBBP Histone Acetyltransferase Domain Mutations Result in Dexamethasone Resistance in B-Progenitor Acute Lymphoblastic Leukemia

Linking Subclonal Genetic Diversity with Functional Heterogeneity Identifies Diagnosis Subclones Destined to Relapse

Outcome of children with hypodiploid ALL treated with risk-directed therapy based on MRD levels

Genomic Landscape of Relapsed Acute Lymphoblastic Leukemia

Inherited GATA3 genetic Variants Are Associated With Childhood BCR-ABL1 -Like Acute Lymphoblastic Leukemia and Increased Risk Of Relapse

Genome-Wide Association Analyses Identify Susceptibility Loci For Vincristine-Induced Peripheral Neuropathy In Children With Acute Lymphoblastic Leukemia

Genome-wide study of methotrexate clearance replicates SLCO1B1

A Genome-Wide Analysis of Variants Influencing Methotrexate Clearance Replicates SLCO1B1 .

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American Society of Hematology

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ASH Publications

American Society of Hematology

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