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Journal Articles

Acute myeloid leukemias with UBTF tandem duplications are sensitive to menin inhibitors

Juan M. Barajas, Milad Rasouli, Masayuki Umeda, Ryan Hiltenbrand, Sherif Abdelhamed, Rebecca Mohnani, Bright Arthur, Tamara Westover, Melvin E. Thomas, III, Minoo Ashtiani, Laura J. Janke, Beisi Xu, Ti-Cheng Chang, Wojciech Rosikiewicz, Emily Xiong, Chandra Rolle, Jonathan Low, Reethu Krishan, Guangchun Song, Michael P. Walsh, Jing Ma, Jeffrey E. Rubnitz, Ilaria Iacobucci, Taosheng Chen, Anja Krippner-Heidenreich, Christian M. Zwaan, Olaf Heidenreich, Jeffery M. Klco
Journal: Blood
Blood (2024) 143 (7): 619–630.
https://doi.org/10.1182/blood.2023021359
Published: 2024
Includes: Supplemental data
Journal Articles

Non-Canonical Transcription Activator Activity of RNA-Binding Protein MBNL1 Uniquely Controls FLT3 expression in MLL-Rearranged Leukemias

Siqi Yi, Shaela Wright, Meixia Che, Judith Hyle, Shelby Mryncza, Beisi Xu, Yong Cheng, Yajun Jiang, Chunliang Li
Journal: Blood
Blood (2023) 142 (Supplement 1): 2760.
https://doi.org/10.1182/blood-2023-185123
Published: 2023
Journal Articles

RNA-Binding Protein RBM5 Plays an Essential Role in Acute Myeloid Leukemia By Activating the Oncogenic Protein HOXA9

Mengli Zhang, Shaela Wright, Xiaowen Chen, Ye Xin, Yingcai Jin, Jianxiang Zhang, Xue Yang, Xinfeng Chen, Judith Hyle, Wojciech Rosikiewicz, Beisi Xu, Liusheng He, Feiqiu Wen, Chunliang Li, Peng Xu
Journal: Blood
Blood (2023) 142 (Supplement 1): 4130.
https://doi.org/10.1182/blood-2023-182595
Published: 2023
Journal Articles

Systematically Interrogating Downstream Regulation Mechanisms of HOXA9 in MLL-r Leukemia Via Functional Noncoding CRISPR Screens

Chunliang Li, Shaela Wright, Xuijie Zhao, Shelby Mryncza, Beisi Xu
Journal: Blood
Blood (2022) 140 (Supplement 1): 1269–1270.
https://doi.org/10.1182/blood-2022-159186
Published: 2022
Journal Articles

FBXO11-mediated proteolysis of BAHD1 relieves PRC2-dependent transcriptional repression in erythropoiesis

Peng Xu, Daniel C. Scott, Beisi Xu, Yu Yao, Ruopeng Feng, Li Cheng, Kalin Mayberry, Yong-Dong Wang, Wenjian Bi, Lance E. Palmer, Moeko T. King, Hong Wang, Yuxin Li, Yiping Fan, Arno F. Alpi, Chunliang Li, Junmin Peng, James Papizan, Shondra M. Pruett-Miller, Ria Spallek, Florian Bassermann, Yong Cheng, Brenda A. Schulman, Mitchell J. Weiss
Journal: Blood
Blood (2021) 137 (2): 155–167.
https://doi.org/10.1182/blood.2020007809
Published: 2021
Includes: Supplemental data
Journal Articles

Enhancer Hijacking of BCL11B Defines a Subtype of Lineage Ambiguous Acute Leukemia

Lindsey Montefiori, PhD, Sonja Seliger, MS, Zhaohui Gu, PhD, Xiaotu Ma, PhD, Beisi Xu, PhD, Xiaolong Chen, PhD, Kirsten Dickerson, BS, Tamara Westover, BS, Anna Stengel, PhD, Ilaria Iacobucci, PhD, Shunsuke Kimura, MD PhD, Chunxu Qu, PhD, Jing Ma, PhD, Marc Valentine, BA, Wolfgang Kern, MD, Torsten Haferlach, MD, Gang Wu, PhD, Jeffery M. Klco, MD PhD, Claudia Haferlach, MD, Charles G Mullighan, MBBS, MD
Journal: Blood
Blood (2020) 136 (Supplement_2): LBA-3.
https://doi.org/10.1182/blood-2020-143881
Published: 2020
Journal Articles

CREBBP Histone Acetyltransferase Domain Mutations Result in Dexamethasone Resistance in B-Progenitor Acute Lymphoblastic Leukemia

Yunchao Chang, PhD, David W. Woessner, PhD MS, Wenwei Lin, PhD, Taosheng Chen, PhD, Beisi Xu, PhD, Yiping Fan, PhD, Haiyan Tan, PhD, Junmin Peng, PhD, Lawryn Kasper, PhD, Michelle L. Churchman, PhD, Mignon L. Loh, MD, Stephen P. Hunger, MD, Aman Seth, PhD, Karen Gascoigne, PhD, Paul K Brindle, PhD, Charles G. Mullighan, MBBS, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 560.
https://doi.org/10.1182/blood.V130.Suppl_1.560.560
Published: 2017