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Laura Janke
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Journal Articles

Zoledronic Acid Reduces Osteonecrosis and Anti-Leukemic Efficacy in Murine Models of Acute Lymphoblastic Leukemia Therapy

Laura Janke, DVM, PhD, Jieun Kim, PhD, David Jenkins, BS, Monique A Payton, BS, Mary V Relling, PharmD, Seth E Karol, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4029.
https://doi.org/10.1182/blood-2018-99-112941
Published: 2018
Journal Articles

Multiplex CRISPR/Cas9-Based Genome Editing of Mouse Hematopoietic Stem Cells Recapitulates Acute Erythroid Leukemia and Identifies Therapeutic Targets

Ilaria Iacobucci, PhD, Elena Varotto, MD, Chunxu Qu, PhD, Laura Janke, DVM, PhD, Aman Seth, PhD, Anang Shelat, PhD, Burgess Freeman, PhD, James Kennedy, Adam S Sperling, MD PhD, R. Coleman Lindsley, MD PhD, Kirsten Dickerson, BS, Debbie Payne-Turner, Sarah M Morris, Nina Ghosn, Benjamin L. Ebert, MDPhD, Charles G. Mullighan, MBBS, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 5.
https://doi.org/10.1182/blood-2018-99-118817
Published: 2018
Journal Articles

Expression of TCF3-ZNF384 in Human Hematopoietic Cells Induces Lineage Disruption in Vitro and Acute Leukemia in Vivo

Kirsten Dickerson, BS, Hiroki Yoshihara, MDPhD, Laura Janke, DVM, PhD, Charles G. Mullighan, MBBS, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 550.
https://doi.org/10.1182/blood-2018-99-118855
Published: 2018
Journal Articles

Evaluation of Nudt15 -Guided Thiopurine Dose Individualization In Vivo Using CRISPR/Cas9-Edited Mouse Model

Takaya Moriyama, MDPhD, Rina Nishii, Laura Janke, DVM, PhD, Lie Li, Chen Ru, Scott A Brown, PhD, Ting-Nien Lin, Chase Suiter, Kentaro Kihira, MD, Hidemi Toyoda, MD PhD, Motohiro Kato, MD PhD, Atushi Manabe, MD PhD, Katsuyoshi Koh, MD, Masatoshi Takagi, MD PhD, Hiroki Hori, MD PhD, Jun J. Yang, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3879.
https://doi.org/10.1182/blood.V130.Suppl_1.3879.3879
Published: 2017
Journal Articles

PAX5 is a tumor suppressor in mouse mutagenesis models of acute lymphoblastic leukemia

Jinjun Dang, Lei Wei, Jeroen de Ridder, Xiaoping Su, Alistair G. Rust, Kathryn G. Roberts, Debbie Payne-Turner, Jinjun Cheng, Jing Ma, Chunxu Qu, Gang Wu, Guangchun Song, Robert G. Huether, Brenda Schulman, Laura Janke, Jinghui Zhang, James R. Downing, Louise van der Weyden, David J. Adams, Charles G. Mullighan
Journal: Blood
Blood (2015) 125 (23): 3609–3617.
https://doi.org/10.1182/blood-2015-02-626127
Published: 2015
Includes: Supplemental data
Journal Articles

Antileukemic Efficacy of Continuous Vs Discontinuous Dexamethasone in Murine Xenografts of Acute Lymphoblastic Leukemia

Laura B. Ramsey, PhD, Laura Janke, DVM, PhD, Monique A. Payton, B.S., Xiangjun Cai, PhD, Sima Jeha, MD, Ching-Hon Pui, MD, William E. Evans, PharmD, Mary V. Relling, PharmD
Journal: Blood
Blood (2014) 124 (21): 3701.
https://doi.org/10.1182/blood.V124.21.3701.3701
Published: 2014
Journal Articles

High Content Screening Identifies Synthetic Lethality Of Retinoid Receptor Agonists In IKZF1 -Mutated BCR-ABL1 positive Acute Lymphoblastic Leukemia

Michelle Churchman, Ph.D., Jonathan Low, Ph.D., Debbie Payne-Turner, Shann-Ching Chen, PhD, Jing Ma, PhD, Mark J. Althoff, Faiyaz Notta, PhD, John E. Dick, PhD, Laura Janke, DVM, PhD, Rodney Kiplin Guy, Ph.D, Taosheng Chen, Ph.D., Charles G. Mullighan, MBBS, MSc, MD, FRACP, FRCPA
Journal: Blood
Blood (2013) 122 (21): 172.
https://doi.org/10.1182/blood.V122.21.172.172
Published: 2013
Journal Articles

Host Thiopurine Methyltransferase Status Affects Mercaptopurine Antileukemic Effectiveness

Laura B. Ramsey, PhD, Laura Janke, DVM, PhD, Mathew Edick, PhD, Cheng Cheng, PhD, Richard T Williams, MBBS, PhD, Charles J. Sherr, MD, PhD, William E. Evans, PharmD, Mary V. Relling, PharmD
Journal: Blood
Blood (2012) 120 (21): 3560.
https://doi.org/10.1182/blood.V120.21.3560.3560
Published: 2012