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Hongjian Jin
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Journal Articles

Venetoclax plus gilteritinib is effective in preclinical models of FLT3 -mutant BCL11B-a lineage-ambiguous leukemia

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Brief Report
Lindsey E. Montefiori, Ilaria Iacobucci, Qingsong Gao, Jamila Moore, William C. Wright, Huimei Wei, Pradyumna Baviskar, Surbhi Sona, Hongjian Jin, Amit Budhraja, Josi Lott, Qi Zhang Tatarata, Zhongshan Cheng, Tanya Khan, Emily A. Backhaus Wagner, Melissa Johnson, Cyrus M. Mehr, Burgess Freeman, Laura Janke, Torsten Haferlach, Paul Geeleher, Paul E. Mead, Marina Konopleva, Joseph T. Opferman, Charles G. Mullighan
Journal: Blood
Blood (2025) 146 (19): 2350–2356.
https://doi.org/10.1182/blood.2025028985
Published: 2025
Includes: Supplemental data
Journal Articles

Single-cell transcriptomic studies reveal altered heterogeneity in CD41 enriched megakaryocytes after targeted therapy in myeloproliferative neoplasm

Free
Man Mohan, Amber Broadhurst, Rashid Mehmood, Lei Li, Hongjian Jin, Anitria Cotton, Andrew Schild, Qi Jin, Jeremy Wen, John Crispino
Journal: Blood
Blood (2025) 146 (Supplement 1): 3764.
https://doi.org/10.1182/blood-2025-3764
Published: 2025
Journal Articles

Neomorphic chromatin engagement and epigenetic reprogramming by the IKZF1 N159Y tandem duplication mutant in b-acute lymphoblastic leukemia

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Ruth Wang'ondu, Devanand Bondage, Qiong Zhang, Yiming Wu, Baranda Hansen, Prady Baviskar, Emily Backhaus, Ilaria Iacobucci, Surbhi Sona, Huiyun Wu, Qingsong Gao, Wojciech Rosikiewicz, Beisi Xu, Hongjian Jin, Ti-Cheng Chang, Gang Wu, Stanley Pounds, Kristine Crews, Jun J. Yang, Shondra Pruett-Miller, Charles Mullighan
Journal: Blood
Blood (2025) 146 (Supplement 1): 1480.
https://doi.org/10.1182/blood-2025-1480
Published: 2025
Journal Articles

Hematopoietic Stem Cell Function and Differentiation Is Regulated By DCAF7 through Polycomb Repressive Complex 1 (PRC1) Modulation

Free
Johanna Melo-Cardenas, Lavanya Bezavada, Te Ling, Amber Broadhurst, Anitria Cotton, Jeremy Chase Crawford, Amanda Nourse, Vishwajeeth Pagala, Qiong Zhang, Wojciech Rosikiewicz, Hongjian Jin, Dirk Loeffler, John D. Crispino
Journal: Blood
Blood (2024) 144 (Supplement 1): 1272.
https://doi.org/10.1182/blood-2024-210287
Published: 2024
Journal Articles

Using Drug-Induced RNA Sequencing and David Analysis to Identify Targeted Therapies for Use in Combination with Duocarmycin SA for the Treatment of Acute Myeloid Leukemia

Free
William A Chen, Valeri Filippov, Jie Fang, Pedro Ochoa, Carlos A Casiano, Hongjian Jin, Sinisa Dovat, Jun J. Yang, Kristopher E Boyle, Olivia Francis
Journal: Blood
Blood (2024) 144 (Supplement 1): 7498.
https://doi.org/10.1182/blood-2024-212174
Published: 2024