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Journal Articles

Disruption of cotranscriptional splicing suggests that RBM39 is a therapeutic target in acute lymphoblastic leukemia

Blood blood.2024024281.

https://doi.org/10.1182/blood.2024024281

Published: 2024

Includes: Supplemental data

Journal Articles

Malignant progression of preleukemic disorders

Trent Hall, Sandeep Gurbuxani, John D. Crispino

Blood (2024) 143 (22): 2245–2255.

https://doi.org/10.1182/blood.2023020817

Published: 2024

Journal Articles

Upregulation of Platelet Transcripts As Biomarkers of Fibrotic Progression in Myeloproliferative Neoplasms

Anitria Cotton, Ryan Collinson, Lynne Wilson, Zi Yun Ng, Hun S Chuah, Michael F. Leahy, Rebecca Howman, Carolyn Grove, Hasib Sidiqi, Malcolm Webb, Darren Boey, Olivia Ruhen, Michael Phillips, Matthew Linden, Kathy Fuller, Wendy N. Erber, Ronald Hoffman, John D. Crispino, Belinda Guo

Blood (2023) 142 (Supplement 1): 4520.

https://doi.org/10.1182/blood-2023-182140

Published: 2023

Journal Articles

Rps19 and Rpl5 Play Distinct Roles in hematopoietic Stem Cell maintenance and Erythroid Differentiation

Yuefeng Tang, Te Ling, Mushran Khan, Riaz Rao, Vincent P Schulz, Julien Papoin, Anupama Narla, Jeffrey Michael Lipton, James Palis, Laurie A. Steiner, Patrick G Gallagher, Mohandas Narla, John D. Crispino, Lionel Blanc

Blood (2023) 142 (Supplement 1): 144.

https://doi.org/10.1182/blood-2023-189146

Published: 2023

Journal Articles

Chromothripsis Orchestrates Leukemic Transformation in Blast Phase MPN through Targetable Amplification of DYRK1A

Blood (2023) 142 (Supplement 1): 993.

https://doi.org/10.1182/blood-2023-178556

Published: 2023

Journal Articles

Ubiquitin Ligase SCF-FBXO11 Controls a Network of RNA-Binding Proteins and Splicing in MDS

Madeline Niederkorn, Lavanya Bezavada, Anitria Cotton, Lance Palmer, Trent Hall, Michael Schieber, Peng Xu, Mitchell Weiss, Raajit K. Rampal, John D. Crispino

Blood (2023) 142 (Supplement 1): 712.

https://doi.org/10.1182/blood-2023-187094

Published: 2023

Journal Articles

Regulation of Alternative Splicing in B-Cell ALL By DYRK1A

Qi Jin, Ethan Harris, Jacquelyn A. Myers, Anitria Cotton, Jeremy Wen, Johanna Melo-Cardenas, Akihide Yoshimi, Omar Abdel-Wahab, Esther A. Obeng, John D. Crispino

Blood (2023) 142 (Supplement 1): 39.

https://doi.org/10.1182/blood-2023-174923

Published: 2023

Journal Articles

Introduction to a review series on hematopoietic stem cells

John D. Crispino

Blood (2023) 142 (6): 497.

https://doi.org/10.1182/blood.2023020909

Published: 2023

Journal Articles

CALR goes rogue

Johanna Melo-Cardenas, John D. Crispino

Blood (2023) 141 (8): 818–820.

https://doi.org/10.1182/blood.2022018788

Published: 2023

Journal Articles

IL-13/IL-4 signaling contributes to fibrotic progression of the myeloproliferative neoplasms

Johanna Melo-Cardenas, Lavanya Bezavada, Jeremy Chase Crawford, Sandeep Gurbuxani, Anitria Cotton, Guolian Kang, Jeffrey Gossett, Christian Marinaccio, Rona Weinberg, Ronald Hoffman, Anna Rita Migliaccio, Yan Zheng, Marta Derecka, Ciro R. Rinaldi, John D. Crispino

Blood (2022) 140 (26): 2805–2817.

https://doi.org/10.1182/blood.2022017326

Published: 2022

Includes: Supplemental data

Journal Articles

Pharmacologic Inhibition of DYRK1A Results in Hyperactivation and Hyperphosphorylation of MYC and ERK Rendering KMT2A-R ALL Cells Sensitive to BCL2 Inhibition

V. S. S. Abhinav Ayyadevara, Gerald Wertheim, John Chukinas, Joseph Patrick Loftus, Sung June Lee, Anil Kumar, Rahul S. Bhansali, Srividya Swaminathan, Thierry Besson, Junwei Shi, John D. Crispino, Sarah K Tasian, Martin P. Carroll, Christian Hurtz

Blood (2022) 140 (Supplement 1): 3486–3488.

https://doi.org/10.1182/blood-2022-162782

Published: 2022

Journal Articles

DDB1 and CUL4 Associated Factor 7 (DCAF7) Is Essential for Hematopoiesis

Johanna Melo-Cardenas, Lavanya Bezavada, Anitria Cotton, John D. Crispino

Blood (2022) 140 (Supplement 1): 8586–8587.

https://doi.org/10.1182/blood-2022-158098

Published: 2022

Journal Articles

Introduction to a review series on megakaryopoiesis and platelet production

John D. Crispino

Blood (2022) 139 (22): 3227.

https://doi.org/10.1182/blood.2022016023

Published: 2022

Journal Articles

Pharmacologic Inhibition of DYRK1A Results in Hyperactivation and Hyperphosphorylation of MYC and ERK Rendering KMT2A-R ALL Cells Sensitive to BCL2 Inhibition

Christian Hurtz, Gerald Wertheim, John Chukinas, Joseph Patrick Loftus, Sung June Lee, Anil Kumar, Rahul S. Bhansali, Srividya Swaminathan, Thierry Besson, Junwei Shi, John D. Crispino, Sarah K Tasian, Martin P. Carroll

Blood (2021) 138 (Supplement 1): 506.

https://doi.org/10.1182/blood-2021-144476

Published: 2021

Journal Articles

The CXCL1 Inhibitor Reparixin Rescues Myelofibrosis in the Gata1 low Model of the Disease

Paola Verachi, Fabrizio Martelli, Maria Zingariello, Francesca Gobbo, Giuseppe Sarli, John D. Crispino, Maria Teresa Massucci, Laura Brandolini, Cristina Giorgio, Marcello Allegretti, Anna Rita Migliaccio

Blood (2021) 138 (Supplement 1): 3579.

https://doi.org/10.1182/blood-2021-147261

Published: 2021

Journal Articles

IL13 Contributes to Fibrotic Progression of the Myeloproliferative Neoplasms

Johanna Melo-Cardenas, Lavanya Bezavada, Jeremy Chase Crawford, Sandeep Gurbuxani, Anitria Cotton, Christian Marinaccio, John D. Crispino

Blood (2021) 138 (Supplement 1): 60.

https://doi.org/10.1182/blood-2021-151492

Published: 2021

Journal Articles

Introduction to a review series on molecular mechanisms of hematologic malignancies

John D. Crispino

Blood (2021) 138 (8): 587.

https://doi.org/10.1182/blood.2021012680

Published: 2021

Journal Articles

Loss of LKB1/ STK11 Facilitates Leukemic Progression of the Myeloproliferative Neoplasms

Christian Marinaccio, MSc, Praveen K Suraneni, PhD, Hamza Celik, PhD, Andrew Volk, PhD, Jeremy Q. Wen, MD PhD, Te Ling, PhD, Terra Lasho, PhD, Richard P. Koche, PhD, Christopher Famulare, MS, Brady L. Stein, MD, Sandeep Gurbuxani, MBBS, PhD, Ronald Hoffman, MD, Naseema Gangat, MBBS, Navdeep Chandel, Ross L. Levine, MD, Raajit K. Rampal, MD PhD, Grant Challen, Ayalew Tefferi, MD, John D. Crispino, PhD

Blood (2020) 136 (Supplement 1): 1.

https://doi.org/10.1182/blood-2020-140557

Published: 2020

Journal Articles

DYRK1A Is Required to Alleviate Replication Stress in KMT2A -Rearranged Acute Lymphoblastic Leukemia

Christian Hurtz, PhD, Martin P. Carroll, MD, Sarah K Tasian, MD, Gerald Wertheim, MD, PhD, Rahul S. Bhansali, MDPhD, Sung June Lee, BA, Anil Kumar, PhD, Anne Lehman, Joseph Patrick Loftus, BS, Grace Jeschke, PhD, John D. Crispino, PhD, Thierry Besson, PhD, Junwei Shi, PhD, Srividya Swaminathan, PhD

Blood (2020) 136 (Supplement 1): 39–40.

https://doi.org/10.1182/blood-2020-141258

Published: 2020

Journal Articles

DYRK1A Is Regulated By Oncogenic KMT2A and Required for Survival of KMT2A -Rearranged Acute Lymphoblastic Leukemia

Christian Hurtz, PhD, Gerald Wertheim, MD, PhD, Rahul S. Bhansali, Anne Lehman, Grace Jeschke, PhD, John D. Crispino, PhD MBA, Thierry Besson, PhD, Sarah K. Tasian, MD, Martin Carroll, MD

Blood (2019) 134 (Supplement_1): 2742.

https://doi.org/10.1182/blood-2019-123475

Published: 2019

NARROW

Disruption of cotranscriptional splicing suggests that RBM39 is a therapeutic target in acute lymphoblastic leukemia

Malignant progression of preleukemic disorders

Upregulation of Platelet Transcripts As Biomarkers of Fibrotic Progression in Myeloproliferative Neoplasms

Rps19 and Rpl5 Play Distinct Roles in hematopoietic Stem Cell maintenance and Erythroid Differentiation

Chromothripsis Orchestrates Leukemic Transformation in Blast Phase MPN through Targetable Amplification of DYRK1A

Ubiquitin Ligase SCF-FBXO11 Controls a Network of RNA-Binding Proteins and Splicing in MDS

Regulation of Alternative Splicing in B-Cell ALL By DYRK1A

Introduction to a review series on hematopoietic stem cells

CALR goes rogue

IL-13/IL-4 signaling contributes to fibrotic progression of the myeloproliferative neoplasms

Pharmacologic Inhibition of DYRK1A Results in Hyperactivation and Hyperphosphorylation of MYC and ERK Rendering KMT2A-R ALL Cells Sensitive to BCL2 Inhibition

DDB1 and CUL4 Associated Factor 7 (DCAF7) Is Essential for Hematopoiesis

Introduction to a review series on megakaryopoiesis and platelet production

Pharmacologic Inhibition of DYRK1A Results in Hyperactivation and Hyperphosphorylation of MYC and ERK Rendering KMT2A-R ALL Cells Sensitive to BCL2 Inhibition

The CXCL1 Inhibitor Reparixin Rescues Myelofibrosis in the Gata1 low Model of the Disease

IL13 Contributes to Fibrotic Progression of the Myeloproliferative Neoplasms

Introduction to a review series on molecular mechanisms of hematologic malignancies

Loss of LKB1/ STK11 Facilitates Leukemic Progression of the Myeloproliferative Neoplasms

DYRK1A Is Required to Alleviate Replication Stress in KMT2A -Rearranged Acute Lymphoblastic Leukemia

DYRK1A Is Regulated By Oncogenic KMT2A and Required for Survival of KMT2A -Rearranged Acute Lymphoblastic Leukemia

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American Society of Hematology

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ASH Publications

American Society of Hematology

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