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Journal Articles

Silencing of BCL11A by disrupting enhancer-dependent epigenetic insulation

Kaili Wang, Juan Wang, Ruopeng Feng, Kseniia Dudnyk, YoonJung Kim, Jun Yi Stanley Lim, Michael Lee, Yuannyu Zhang, Xiaofei Gao, Yong Cheng, Stuart Orkin, Jian Zhou, Mitchell Weiss, Feng Yue, Jian Xu

Blood (2025) 146 (Supplement 1): 732.

https://doi.org/10.1182/blood-2025-732

Published: 2025

Journal Articles

Heme-regulated eIF2α (HRI) is required during iron restriction to alleviate ß-thalassemia via mTORC1 inhibition, autophagy activation, and suppression of protein synthesis, contributing to clearance of toxic free α-globin

Alfonso Fernandez, Georgios Christakopoulos, Michael Dudley, Yu Yao, Jingjing Zhang, Xiaohui Qiu, Harsha Garadi Suresh, Sukhmanjit Kaur, Guolian Kang, Jane-Jane Chen, Vania Manolova, Elizabeta Nemeth, Tomas Ganz, Mitchell Weiss

Blood (2025) 146 (Supplement 1): 728.

https://doi.org/10.1182/blood-2025-728

Published: 2025

Journal Articles

Single-cell analysis reveals distinct γ-globin expression profiles in sickle cell disease with pancellular fetal hemoglobin

Phillip Doerfler, Yichao Li, Yu Yao, Ruopeng Feng, Thiyagaraj Mayuranathan, Jingjing Zhang, Emilia Kooienga, David Cullins, Rohith Jesudas, Dillon Williams, David Wood, Jane Hankins, Yong Cheng, Mitchell Weiss

Blood (2025) 146 (Supplement 1): 1149.

https://doi.org/10.1182/blood-2025-1149

Published: 2025

Journal Articles

Ubiquitin Ligase SCF-FBXO11 Controls a Network of RNA-Binding Proteins and Splicing in MDS

Madeline Niederkorn, Lavanya Bezavada, Anitria Cotton, Lance Palmer, Trent Hall, Michael Schieber, Peng Xu, Mitchell Weiss, Raajit K. Rampal, John D. Crispino

Blood (2023) 142 (Supplement 1): 712.

https://doi.org/10.1182/blood-2023-187094

Published: 2023

Journal Articles

Optimization of RH Genotyping from Whole Exon Sequencing Data By Machine Learning

Ti-Cheng Chang, Jing Yu, Zhaoming Wang, Jane S Hankins, Mitchell Weiss, Gang Wu, Connie M. Westhoff, Sunitha Vege, Stella Chou, Yan Zheng

Blood (2023) 142 (Supplement 1): 4034.

https://doi.org/10.1182/blood-2023-182089

Published: 2023

Journal Articles

Efficient and Stable Makassar Base Editing in Nonhuman Primates

Stefan Radtke, Emily Fields, Gregory A. Newby, Jonathan S Yen, Mitchell Weiss, Olivier Humbert, Dnyanada Pande, Mark Enstrom, David Liu, Hans-Peter Kiem

Blood (2023) 142 (Supplement 1): 484.

https://doi.org/10.1182/blood-2023-178732

Published: 2023

Journal Articles

Development of a Genetic Risk Score for Albuminuria in Pediatric Patients with Sickle Cell Anemia

Rima Zahr, Guolian Kang, Sara Rashkin, Yutaka Yasui, Csaba Kovesdy, Clifford M Takemoto, Jeffrey D. Lebensburger, Mitchell Weiss, Santosh L. Saraf, Kenneth I. Ataga

Blood (2023) 142 (Supplement 1): 1141.

https://doi.org/10.1182/blood-2023-185213

Published: 2023

Journal Articles

Development of a Mouse Model of DS Megakaryoblastic Leukemia and Identification of the Hsa21 Gene DYRK1A as a Prominent Contributor to DS-AMKL

Sebastien Malinge, PhD, Gina Kirsammer, PhD, Meghan Bliss-Moreau, Timothy M Chlon, Lauren Diebold, Stella T Chou, MD, Mitchell Weiss, MD, Sandeep Gurbuxani, MBBS, PhD, John Crispino, PhD

Blood (2010) 116 (21): 469.

https://doi.org/10.1182/blood.V116.21.469.469

Published: 2010

Journal Articles

A global role for EKLF in definitive and primitive erythropoiesis

Denise Hodge, Elise Coghill, Janelle Keys, Tina Maguire, Belinda Hartmann, Alasdair McDowall, Mitchell Weiss, Sean Grimmond, Andrew Perkins

Blood (2006) 107 (8): 3359–3370.

https://doi.org/10.1182/blood-2005-07-2888

Published: 2006

Journal Articles

A Global Role for EKLF in Definitive and Primitive Erythropoiesis.

Andrew C. Perkins, MBBS, PhD, Elise Coghill, PhD, Tina Maguire, PhD, Belinda Hartmann, BSc, Alasdair McDowall, PhD, Mitchell Weiss, MD, PhD, Sean Grimmond, PhD, Janelle Keys, PhD, Denise Hodge, PhD

Blood (2005) 106 (11): 1745.

https://doi.org/10.1182/blood.V106.11.1745.1745

Published: 2005

Journal Articles

Chromatin Remodeling of the Mouse AHSP Gene Requires EKLF.

Andre M. Pilon, BA, Clara Wong, MS, Lisa J. Garrett-Beal, MS, Mitchell Weiss, MD, PhD, Patrick G. Gallagher, MD, David M. Bodine, PhD

Blood (2004) 104 (11): 375.

https://doi.org/10.1182/blood.V104.11.375.375

Published: 2004

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Silencing of BCL11A by disrupting enhancer-dependent epigenetic insulation

Heme-regulated eIF2α (HRI) is required during iron restriction to alleviate ß-thalassemia via mTORC1 inhibition, autophagy activation, and suppression of protein synthesis, contributing to clearance of toxic free α-globin

Single-cell analysis reveals distinct γ-globin expression profiles in sickle cell disease with pancellular fetal hemoglobin

Ubiquitin Ligase SCF-FBXO11 Controls a Network of RNA-Binding Proteins and Splicing in MDS

Optimization of RH Genotyping from Whole Exon Sequencing Data By Machine Learning

Efficient and Stable Makassar Base Editing in Nonhuman Primates

Development of a Genetic Risk Score for Albuminuria in Pediatric Patients with Sickle Cell Anemia

Development of a Mouse Model of DS Megakaryoblastic Leukemia and Identification of the Hsa21 Gene DYRK1A as a Prominent Contributor to DS-AMKL

A global role for EKLF in definitive and primitive erythropoiesis

A Global Role for EKLF in Definitive and Primitive Erythropoiesis.

Chromatin Remodeling of the Mouse AHSP Gene Requires EKLF.

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American Society of Hematology

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