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Gregory A. Newby
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Journal Articles

Efficient and Stable Makassar Base Editing in Nonhuman Primates

Stefan Radtke, Emily Fields, Gregory A. Newby, Jonathan S Yen, Mitchell Weiss, Olivier Humbert, Dnyanada Pande, Mark Enstrom, David Liu, Hans-Peter Kiem
Journal: Blood
Blood (2023) 142 (Supplement 1): 484.
https://doi.org/10.1182/blood-2023-178732
Published: 2023
Journal Articles

In vivo HSC prime editing rescues sickle cell disease in a mouse model

Chang Li, Aphrodite Georgakopoulou, Gregory A. Newby, Peter J. Chen, Kelcee A. Everette, Kiriaki Paschoudi, Efthymia Vlachaki, Sucheol Gil, Anna K. Anderson, Theodore Koob, Lishan Huang, Hongjie Wang, Hans-Peter Kiem, David R. Liu, Evangelia Yannaki, André Lieber
Journal: Blood
Blood (2023) 141 (17): 2085–2099.
https://doi.org/10.1182/blood.2022018252
Published: 2023
Includes: Supplemental data
Journal Articles

Comparing the Impact of NHEJ-CRISPR/Cas9 and Base Gene Editing on Rhesus Macaque Hematopoietic Stem Cell Clonal Behavior and Integrity

Diana M. Abraham, Yifan Zhou, Richard Lozano, Gregory A. Newby, David R. Liu, Chuanfeng Wu, Cynthia E. Dunbar
Journal: Blood
Blood (2022) 140 (Supplement 1): 4926–4927.
https://doi.org/10.1182/blood-2022-167373
Published: 2022
Journal Articles

Base Editing of Hematopoietic Stem Cells Rescues T-Cell Development for CD3d Severe Combined Immunodeficiency

Grace McAuley, Gloria Yiu, Gregory A. Newby, Beatriz Campo Fernandez, Xiaomeng Wu, Patrick Chang, Kelcee Everette, Zulema Romero Garcia, David R. Liu, Gay M. Crooks, Donald B. Kohn
Journal: Blood
Blood (2022) 140 (Supplement 1): 1641–1642.
https://doi.org/10.1182/blood-2022-170634
Published: 2022
Journal Articles

Increased Potency and Uniformity of Fetal Hemoglobin Induction from Base Editing Compared to Cas9 Nuclease

Thiyagaraj Mayuranathan, Gregory A. Newby, Ruopeng Feng, Yu Yao, Kalin Mayberry, Guolian Kang, Cicera Lazzarotto, Yichao Li, Rachel Levine, Erin Dempsey, Shaina N. Porter, Phillip A Doerfler, Jingjing Zhang, Yoonjeong Jang, Senthil Bhoopalan, Nikitha Nimmagadda, Akshay Sharma, John Tisdale, Shondra Miller, Yong Cheng, Shengdar Tsai, Mitchell J. Weiss, David R. Liu, Jonathan S Yen
Journal: Blood
Blood (2022) 140 (Supplement 1): 7784–7785.
https://doi.org/10.1182/blood-2022-162639
Published: 2022
Journal Articles

Adenosine Base Editing of γ-Globin Promoters Induces Fetal Hemoglobin and Inhibit Erythroid Sickling

Thiyagaraj Mayuranathan, Jonathan S. Yen, PhD, Gregory A. Newby, PhD, Yu Yao, MD, Shaina N. Porter, PhD, Kaitly J. Woodard, BS, Jingjing Zhang, MS, Kalin Mayberry, BS, Akshay Sharma, MBBS, Shondra M. preutt-Miller, PhD, John F. Tisdale, MD, Shengdar Q. Tsai, PhD, David R. Liu, PhD, Mitchell J. Weiss, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 21–22.
https://doi.org/10.1182/blood-2020-141498
Published: 2020
Journal Articles

Base Editing Eliminates the Sickle Cell Mutation and Pathology in Hematopoietic Stem Cells Derived Erythroid Cells

Jonathan S Yen, PhD, Gregory A. Newby, PhD, Thiyagaraj Mayuranathan, Shaina N. Porter, PhD, Yu Yao, MD, Kaitly J. Woodard, BS, Kalin Mayberry, BS, Kelcee Everette, Jingjing Zhang, MS, Jordana M Henderson, MS, Anton P Mccaffrey, Jonathan Yen, John F. Tisdale, MD, Shengdar Q. Tsai, PhD, David R. Liu, PhD, Mitchell J. Weiss, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 13–14.
https://doi.org/10.1182/blood-2020-139016
Published: 2020