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Journal Articles

Utility of Peripheral Blood Testing for Detection and Surveillance of Clonal Hematopoiesis in Predisposed Individuals (CH-IPI)

Blood blood.2024028042.

https://doi.org/10.1182/blood.2024028042

Published: 2025

Includes: Supplemental data

Journal Articles

Heme-regulated eIF2α (HRI) is required during iron restriction to alleviate ß-thalassemia via mTORC1 inhibition, autophagy activation, and suppression of protein synthesis, contributing to clearance of toxic free α-globin

Alfonso Fernandez, Georgios Christakopoulos, Michael Dudley, Yu Yao, Jingjing Zhang, Xiaohui Qiu, Harsha Garadi Suresh, Sukhmanjit Kaur, Guolian Kang, Jane-Jane Chen, Vania Manolova, Elizabeta Nemeth, Tomas Ganz, Mitchell Weiss

Blood (2025) 146 (Supplement 1): 728.

https://doi.org/10.1182/blood-2025-728

Published: 2025

Journal Articles

Novel trajectory-informed mendelian randomization demonstrates consistent causal protective effect of fetal hemoglobin on clinical outcomes in children with sickle cell disease

Chengzhou Wu, Clifford Takemoto, Kumar Srivastava, Tomi Mori, Guolian Kang

Blood (2025) 146 (Supplement 1): 2934.

https://doi.org/10.1182/blood-2025-2934

Published: 2025

Journal Articles

Hydroxyurea use does not worsen age-related decline in blood counts in sickle cell disease

Parul Rai, Guolian Kang, Matthew Wogksch, Kenneth Ataga

Blood (2025) 146 (Supplement 1): 6229.

https://doi.org/10.1182/blood-2025-6229

Published: 2025

Journal Articles

The impact of duffy-null phenotype on neutrophil counts in patients with HbSC/ HbSβ+-thalassemia treated with hydroxyurea

Yan Zheng, Jeffrey Gossett, Matthew Wogksch, Guolian Kang, Clifford Takemoto

Blood (2025) 146 (Supplement 1): 1182.

https://doi.org/10.1182/blood-2025-1182

Published: 2025

Journal Articles

Avascular necrosis of the femoral head in children and adolescents with sickle cell disease presenting with HIP PAIN

Khalid Elbashir, Parul Rai, Yogindra Persaud, Tomas Bryndziar, Ragha Srinivasan, Guolian Kang, Oyebimpe Adesina, Clifford Takemoto

Blood (2025) 146 (Supplement 1): 4736.

https://doi.org/10.1182/blood-2025-4736

Published: 2025

Journal Articles

Sickle Cell Disease-Related Worry and Associations with Healthcare Utilization in Youth with Sickle Cell Disease

Alex Pizzo, Guolian Kang, Victoria Okhomina, Jerlym Porter, Jason Hodges, Parul Rai, Clifford M. Takemoto, Jane S Hankins, Nicole M. Alberts

Blood (2024) 144 (Supplement 1): 1065.

https://doi.org/10.1182/blood-2024-202603

Published: 2024

Journal Articles

Low Bone Density Associates with Severe Outcomes in Young Adults with Sickle Cell Disease

Jahnavi Gollamudi, Guolian Kang, Michael Sexton Lamonica, Lindsey Hornung, Pei-Lin Chen, Babette S Zemel, Oyebimpe Adesina

Blood (2024) 144 (Supplement 1): 3900.

https://doi.org/10.1182/blood-2024-210160

Published: 2024

Journal Articles

The Natural History of Glomerular Hyperfiltration in Sickle Cell Disease

Rima Zahr, Shuyan Chen, Parul Rai, Jane S Hankins, Winfred C. Wang, Jeffrey D Lebensburger, Guolian Kang, Kenneth I. Ataga

Blood (2024) 144 (Supplement 1): 3886.

https://doi.org/10.1182/blood-2024-199586

Published: 2024

Journal Articles

Health-Related Communication in Adolescents and Young Adults with Sickle Cell Disease

Tori Langmuir, Guolian Kang, Doralina Anghelescu, Jason Hodges, Jerlym Porter, Keesha Roach, Jane S Hankins, Parul Rai, Clifford M. Takemoto, Nicole M. Alberts

Blood (2024) 144 (Supplement 1): 3688.

https://doi.org/10.1182/blood-2024-202138

Published: 2024

Journal Articles

A Retrospective Study of First and Recurrent Venous Thromboembolism in Patients with Acute Lymphoblastic Leukemia Treated on Total XV and Total Xvi Protocols

Rohith Jesudas, Justin Kirkham, Tomas Bryndziar, Hiroto Inaba, Timothy Jacobs, Sima Jeha, Victoria Okhomina, Guolian Kang, Cheng Cheng, Clifford M. Takemoto, Ching-Hon Pui, Seth E. Karol

Blood (2024) 144 (Supplement 1): 7707.

https://doi.org/10.1182/blood-2024-210355

Published: 2024

Journal Articles

Impact of Duffy-Null Phenotype on Neutrophil Counts and Clinical Outcomes in Patients with Sickle Cell Disease and without Hydroxyurea

Yan Zheng, Jeffery Gossett, Guolian Kang, Pei-Lin Chen, Clifford M. Takemoto

Blood (2024) 144 (Supplement 1): 1129.

https://doi.org/10.1182/blood-2024-198232

Published: 2024

Journal Articles

Vaso-Occlusive Crisis in Patients with Sickle Cell Anemia with Elevated Fetal Hemoglobin

Parul Rai, Rohith Jesudas, Guolian Kang, Clifford M. Takemoto, Yunusa Olufadi, Pei-Lin Chen, Phillip A Doerfler

Blood (2024) 144 (Supplement 1): 5063.

https://doi.org/10.1182/blood-2024-208481

Published: 2024

Journal Articles

Sickle Cell Genotype and Biomarkers of Endothelial Dysfunction Predict Early Kidney Disease in Patients with APOL1 High Risk Variants

Jeffrey D Lebensburger, Guolian Kang, Sara Rashkin, Rima Zahr, Malgorzata Kasztan

Blood (2024) 144 (Supplement 1): 803.

https://doi.org/10.1182/blood-2024-203474

Published: 2024

Journal Articles

Development of a Genetic Risk Score for Albuminuria in Pediatric Patients with Sickle Cell Anemia

Rima Zahr, Guolian Kang, Sara Rashkin, Yutaka Yasui, Csaba Kovesdy, Clifford M Takemoto, Jeffrey D. Lebensburger, Mitchell Weiss, Santosh L. Saraf, Kenneth I. Ataga

Blood (2023) 142 (Supplement 1): 1141.

https://doi.org/10.1182/blood-2023-185213

Published: 2023

Journal Articles

Stable Therapeutic Transgenic FIX Levels for More Than 10 Years in Subjects with Severe Hemophilia B Who Received scAAV2/8-LP1-Hfixco Adeno-Associated Virus Gene Therapy

Blood (2023) 142 (Supplement 1): 1056.

https://doi.org/10.1182/blood-2023-186891

Published: 2023

Journal Articles

Sleep Fragmentation and Obstructive Sleep Apnea Are Associated with High Primary Stroke Risk in Children with Sickle Cell Disease

Zachary Abramson, La'Ron Browne, Ayobami Olanrewaju, Guolian Kang, Yunus Olufadi, Andrew M Heitzer, Ahsan Bashir, Kevin R. Krull, Jane S Hankins

Blood (2023) 142 (Supplement 1): 795.

https://doi.org/10.1182/blood-2023-185094

Published: 2023

Journal Articles

The Impact of Socio-Economic Determinants of Health on PedsQL and Pain Outcomes Among Individuals with Sickle Cell Disease

Yogindra Persaud, Victoria Okhomina, Andrew M Heitzer, Hamda Khan, Jason Robert Hodges, Parul Rai, Clifford M Takemoto, Deepika S. Darbari, Guolian Kang, Doralina Anghelescu

Blood (2023) 142 (Supplement 1): 250.

https://doi.org/10.1182/blood-2023-188145

Published: 2023

Journal Articles

GO-8: Stable Expression of Factor VIII over 5 Years Following Adeno-Associated Gene Transfer in Subjects with Hemophilia a Using a Novel Human Factor VIII Variant

Blood (2023) 142 (Supplement 1): 3624.

https://doi.org/10.1182/blood-2023-180803

Published: 2023

Journal Articles

Birth-Related Risk Factors Impact Cognitive and Academic Outcomes in Children with Sickle Cell Disease

Jennifer N Longoria, Andrew M Heitzer, Joshua Semko, Halle T McCracken, Erin MacArthur, Guolian Kang, Catherine R Hoyt, Jane S Hankins, Clifford M Takemoto

Blood (2023) 142 (Supplement 1): 5128.

https://doi.org/10.1182/blood-2023-186586

Published: 2023

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Utility of Peripheral Blood Testing for Detection and Surveillance of Clonal Hematopoiesis in Predisposed Individuals (CH-IPI)

Heme-regulated eIF2α (HRI) is required during iron restriction to alleviate ß-thalassemia via mTORC1 inhibition, autophagy activation, and suppression of protein synthesis, contributing to clearance of toxic free α-globin

Novel trajectory-informed mendelian randomization demonstrates consistent causal protective effect of fetal hemoglobin on clinical outcomes in children with sickle cell disease

Hydroxyurea use does not worsen age-related decline in blood counts in sickle cell disease

The impact of duffy-null phenotype on neutrophil counts in patients with HbSC/ HbSβ+-thalassemia treated with hydroxyurea

Avascular necrosis of the femoral head in children and adolescents with sickle cell disease presenting with HIP PAIN

Sickle Cell Disease-Related Worry and Associations with Healthcare Utilization in Youth with Sickle Cell Disease

Low Bone Density Associates with Severe Outcomes in Young Adults with Sickle Cell Disease

The Natural History of Glomerular Hyperfiltration in Sickle Cell Disease

Health-Related Communication in Adolescents and Young Adults with Sickle Cell Disease

A Retrospective Study of First and Recurrent Venous Thromboembolism in Patients with Acute Lymphoblastic Leukemia Treated on Total XV and Total Xvi Protocols

Impact of Duffy-Null Phenotype on Neutrophil Counts and Clinical Outcomes in Patients with Sickle Cell Disease and without Hydroxyurea

Vaso-Occlusive Crisis in Patients with Sickle Cell Anemia with Elevated Fetal Hemoglobin

Sickle Cell Genotype and Biomarkers of Endothelial Dysfunction Predict Early Kidney Disease in Patients with APOL1 High Risk Variants

Development of a Genetic Risk Score for Albuminuria in Pediatric Patients with Sickle Cell Anemia

Stable Therapeutic Transgenic FIX Levels for More Than 10 Years in Subjects with Severe Hemophilia B Who Received scAAV2/8-LP1-Hfixco Adeno-Associated Virus Gene Therapy

Sleep Fragmentation and Obstructive Sleep Apnea Are Associated with High Primary Stroke Risk in Children with Sickle Cell Disease

The Impact of Socio-Economic Determinants of Health on PedsQL and Pain Outcomes Among Individuals with Sickle Cell Disease

GO-8: Stable Expression of Factor VIII over 5 Years Following Adeno-Associated Gene Transfer in Subjects with Hemophilia a Using a Novel Human Factor VIII Variant

Birth-Related Risk Factors Impact Cognitive and Academic Outcomes in Children with Sickle Cell Disease

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