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Journal Articles

Clonal evolution of pediatric Acute Myeloid Leukemia

Masayuki Umeda, Pandurang Kolekar, Anna Huskey, Shruthi Suryaprakash, Hanxia Li, Tamara Westover, Jing Ma, Mike Walsh, Guangchun Song, Yanling Liu, Quang Tran, Seth Karol, Hiroto Inaba, Jeffrey Rubnitz, Raul Ribeiro, Xiaotu Ma, Jeffery Klco

Blood (2025) 146 (Supplement 1): 1721.

https://doi.org/10.1182/blood-2025-1721

Published: 2025

Journal Articles

Impact of noncoding tandem repeat sequence on TPMT function and thiopurine metabolism in children with ALL

Jason Xu, Wenjian Yang, Kristine Crews, Alejandro Molinelli, Sima Jeha, Ching-Hon Pui, Seth Karol, Hiroto Inaba, Jun J. Yang

Blood (2025) 146 (Supplement 1): 332.

https://doi.org/10.1182/blood-2025-332

Published: 2025

Journal Articles

Clinical characteristics and outcomes of children with T-cell acute lymphoblastic leukemia harboring ABL-class fusions: A report from the ponte di legno consortium

Blood (2025) 146 (Supplement 1): 761.

https://doi.org/10.1182/blood-2025-761

Published: 2025

Journal Articles

Epigenetic priming improves survival for pediatric Acute Myeloid Leukemia: Results from the multicenter randomized AML16 trial

Blood (2025) 146 (Supplement 1): 3446.

https://doi.org/10.1182/blood-2025-3446

Published: 2025

Journal Articles

A prospective, single site, single-arm pilot study of CPX-351 (Vyxeos) in individuals <22 years with secondary myeloid neoplasms

Alyssa Kennedy, Yonghui Ni, Stanley Pounds, Jatinder Lamba, Hiroto Inaba, Matthew Rees, Amr Qudeimat, Emily Montgomery, Raul Ribeiro, Marcin Wlodarski

Blood (2025) 146 (Supplement 1): 2097.

https://doi.org/10.1182/blood-2025-2097

Published: 2025

Journal Articles

Clinical, cytogenetic and molecular characteriszation of Mecom- rearranged pediatric de novo Acute Myeloid Leukemia (AML): A retrospective cohort study of the international-berlin-frankfurt-Münster (I-BFM) AML-study group

Blood (2025) 146 (Supplement 1): 1608.

https://doi.org/10.1182/blood-2025-1608

Published: 2025

Journal Articles

Relapsed acute lymphoblastic leukemia treated with venetoclax and navitoclax: Results of the raven study in children and young adults with relapsed/ refractory ALL

Seth Karol, Maria Luisa Sulis, Yinmei Zhou, Satoshi Yoshimura, Wenjian Yang, Qingsong Gao, Matthew Rees, Hiroto Inaba, Raul Ribeiro, Cheng Cheng, Charles Mullighan, Jun J. Yang, Ching-Hon Pui

Blood (2025) 146 (Supplement 1): 5126.

https://doi.org/10.1182/blood-2025-5126

Published: 2025

Journal Articles

Tallforest: Multi-omic classifier for T-lineage acute lymphoblastic leukemia

Petri Polonen, Yiping Fan, Shaohua Lei, Qingsong Gao, Yiming Wu, Ti-Cheng Chang, Haley Newman, Lahari Uppuluri, Niroshan Nadarajah, Torsten Haferlach, Marketa Zaliova, Jan Trka, Lu Wang, Hiroto Inaba, Stanley Pounds, Gang Wu, David Teachey, Charles Mullighan

Blood (2025) 146 (Supplement 1): 336.

https://doi.org/10.1182/blood-2025-336

Published: 2025

Journal Articles

Fusion oncoproteins and cooperating mutations define disease phenotypes in NUP98 -rearranged leukemia

Blood (2025) 146 (17): 2102–2118.

https://doi.org/10.1182/blood.2025028993

Published: 2025

Includes: Supplemental data

Journal Articles

Differentiation-dependent EBF1 activity determines CD22 transcription and leukemia sensitivity to inotuzumab ozogamicin

Blood (2025) 146 (4): 471–481.

https://doi.org/10.1182/blood.2024028215

Published: 2025

Includes: Supplemental data

Journal Articles

DNTT-mediated DNA damage response drives inotuzumab ozogamicin resistance in B-cell acute lymphoblastic leukemia

Blood (2025) 145 (11): 1182–1194.

https://doi.org/10.1182/blood.2024026085

Published: 2025

Includes: Supplemental data

Journal Articles

Outcomes in patients with ETV6 :: RUNX1 or high-hyperdiploid B-ALL treated in the St. Jude Total Therapy XV/XVI studies

Katelyn Purvis, Yinmei Zhou, Seth E. Karol, Jeffrey E. Rubnitz, Raul C. Ribeiro, Shawn Lee, Jun J. Yang, W. Paul Bowman, Lu Wang, Stephanie B. Dixon, Kathryn G. Roberts, Qingsong Gao, Cheng Cheng, Charles G. Mullighan, Sima Jeha, Ching-Hon Pui, Hiroto Inaba

Blood (2025) 145 (2): 190–201.

https://doi.org/10.1182/blood.2024024936

Published: 2025

Includes: Supplemental data

Journal Articles

Safety and Feasibility of Blinatumomab As Frontline Therapy for Pediatric Patients with B-Acute Lymphoblastic Leukemia and Lymphoma: St. Jude Total Therapy Study XVII

Caitlyn Duffy, Elizabeth Dang, Zhou Yinmei, Jessica Bell, Nickhill Bhakta, Meret Henry, Kenneth Matthew Heym, Sima Jeha, Norman J. Lacayo, Seth E. Karol, Seong Lin Khaw, Raul C. Ribeiro, Deborah E. Schiff, Charles G. Mullighan, Jun J. Yang, Cheng Cheng, Ching-Hon Pui, Hiroto Inaba

Blood (2024) 144 (Supplement 1): 4208.

https://doi.org/10.1182/blood-2024-209284

Published: 2024

Journal Articles

A Retrospective Study of First and Recurrent Venous Thromboembolism in Patients with Acute Lymphoblastic Leukemia Treated on Total XV and Total Xvi Protocols

Rohith Jesudas, Justin Kirkham, Tomas Bryndziar, Hiroto Inaba, Timothy Jacobs, Sima Jeha, Victoria Okhomina, Guolian Kang, Cheng Cheng, Clifford M. Takemoto, Ching-Hon Pui, Seth E. Karol

Blood (2024) 144 (Supplement 1): 7707.

https://doi.org/10.1182/blood-2024-210355

Published: 2024

Journal Articles

EBF1 Activity Controls Leukemia Sensitivity to Inotuzumab Ozogamicin

Carolin S. Escherich, Zhenhua Li, Kelly R. Barnett, Yizhen Li, Megan Walker, Wenjian Yang, Xin Huang, Jiyang Yu, Wendy Stock, Elisabeth Paietta, Marina Konopleva, Steven M. Kornblau, Mark R. Litzow, Hiroto Inaba, Ching-Hon Pui, Mignon L. Loh, Daniel Savic, Jun J. Yang

Blood (2024) 144 (Supplement 1): 830.

https://doi.org/10.1182/blood-2024-198800

Published: 2024

Journal Articles

Germ line genetic NBN variation and predisposition to B-cell acute lymphoblastic leukemia in children

Carolin S. Escherich, Wenan Chen, Yizhen Li, Wenjian Yang, Rina Nishii, Zhenhua Li, Elizabeth A. Raetz, Meenakshi Devidas, Gang Wu, Kim E. Nichols, Hiroto Inaba, Ching-Hon Pui, Sima Jeha, Bruce M. Camitta, Eric Larsen, Stephen P. Hunger, Mignon L. Loh, Jun J. Yang

Blood (2024) 143 (22): 2270–2283.

https://doi.org/10.1182/blood.2023023336

Published: 2024

Includes: Supplemental data

Journal Articles

The Impact of Age and Genomics on Drug Sensitivity in 1,076 Children and Adults with B-Cell Acute Lymphoblastic Leukemia

Blood (2023) 142 (Supplement 1): 596.

https://doi.org/10.1182/blood-2023-181788

Published: 2023

Journal Articles

Intensification of Therapy and Pharmacogenetic Personalization Mitigate Racial Disparities in Pediatric Acute Myeloid Leukemia Outcomes

Jatinder K. Lamba, Richard J Marrero, Huiyun Wu, Xueyuan Cao, Phani Krishna Parcha, Seth E. Karol, Hiroto Inaba, Dennis John Kuo, Barbara Degar, Kenneth Matthew Heym, Jeffrey Taub, Norman J. Lacayo, Ching-Hon Pui, Raul C. Ribeiro, Stanley Pounds, Jeffrey E. Rubnitz

Blood (2023) 142 (Supplement 1): 386.

https://doi.org/10.1182/blood-2023-173617

Published: 2023

Journal Articles

Evaluating Blinatumomab Treatment Adoption in Varied Resource Settings Using the RE-AIM Framework

Caitlyn Duffy, Zehra Fadoo, Niharendu Ghara, Victor Santana, Hiroto Inaba, Sima Jeha, Yichen Chen, Linh Pham, Hyun Jy Chung, Meenakshi Devidas, Nickhill Bhakta, Heather Brandt

Blood (2023) 142 (Supplement 1): 3713.

https://doi.org/10.1182/blood-2023-190228

Published: 2023

Journal Articles

STAG2/LMO2 Gamma-Delta (γδ) T-ALL: Identification and Characterization of an Extremely High Risk Group of T-ALL in the Very Young

Shunsuke Kimura, Petri Pölönen, Lindsey Montefiori, Kenneth Caldwell, Ilaria Iacobucci, Chelsey Chen, Anthony Brown, Katie Han, Yen-Chun Liu, Yunchao Chang, Zhongshan Cheng, Zhou Yinmei, Chun Shik Park, Sharnise Mitchell, Noemi Reyes, Allen Yeoh, Andishe Attarbaschi, Andrew Moore, Atsushi Manabe, Barbara Buldini, Kean Hui Chiew, Chi Kong Li, Ching-Hon Pui, Chunxu Qu, Daisuke Tomizawa, Elisabeth Paietta, Franco Locatelli, Gabriele Escherich, Gao Qingsong, Hannah Elisa Muhle, Hanne Vibeke Marquart, Hester A. de Groot-Kruseman, Jacob M. Rowe, Jan Stary, Jan Trka, John Kim Choi, Jules P.P. Meijerink, Junko Takita, Katarzyna Pawinska-Wasikowska, Kjeld Schmiegelow, Mariko Eguchi, Martin Schrappe, Martin Zimmermann, Masatoshi Takagi, Melissa Maybury, Michael Svaton, Michaela Reiterova, Michal Kicinski, Motohiro Kato, Orietta Spinelli, Pauline Mazilier, Paul G. Thomas, Riccardo Masetti, Rishi Sury Kotecha, Rob Pieters, Sarah Elitzur, Selina M Luger, Shuhong Shen, Sima Jeha, Steven M. Kornblau, Szymon Skoczen, Takako Miyamura, Tiffaney Vincent, Toshihiko Imamura, Valentino Conter, Yanjing Tang, Zhaohui Gu, Kathryn G. Roberts, David T. Teachey, Kristine R Crews, Cheng Cheng, Jun J. Yang, Hiroto Inaba, Charles G. Mullighan

Blood (2023) 142 (Supplement 1): 845.

https://doi.org/10.1182/blood-2023-178688

Published: 2023

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Clonal evolution of pediatric Acute Myeloid Leukemia

Impact of noncoding tandem repeat sequence on TPMT function and thiopurine metabolism in children with ALL

Clinical characteristics and outcomes of children with T-cell acute lymphoblastic leukemia harboring ABL-class fusions: A report from the ponte di legno consortium

Epigenetic priming improves survival for pediatric Acute Myeloid Leukemia: Results from the multicenter randomized AML16 trial

A prospective, single site, single-arm pilot study of CPX-351 (Vyxeos) in individuals <22 years with secondary myeloid neoplasms

Clinical, cytogenetic and molecular characteriszation of Mecom- rearranged pediatric de novo Acute Myeloid Leukemia (AML): A retrospective cohort study of the international-berlin-frankfurt-Münster (I-BFM) AML-study group

Relapsed acute lymphoblastic leukemia treated with venetoclax and navitoclax: Results of the raven study in children and young adults with relapsed/ refractory ALL

Tallforest: Multi-omic classifier for T-lineage acute lymphoblastic leukemia

Fusion oncoproteins and cooperating mutations define disease phenotypes in NUP98 -rearranged leukemia

Differentiation-dependent EBF1 activity determines CD22 transcription and leukemia sensitivity to inotuzumab ozogamicin

DNTT-mediated DNA damage response drives inotuzumab ozogamicin resistance in B-cell acute lymphoblastic leukemia

Outcomes in patients with ETV6 :: RUNX1 or high-hyperdiploid B-ALL treated in the St. Jude Total Therapy XV/XVI studies

Safety and Feasibility of Blinatumomab As Frontline Therapy for Pediatric Patients with B-Acute Lymphoblastic Leukemia and Lymphoma: St. Jude Total Therapy Study XVII

A Retrospective Study of First and Recurrent Venous Thromboembolism in Patients with Acute Lymphoblastic Leukemia Treated on Total XV and Total Xvi Protocols

EBF1 Activity Controls Leukemia Sensitivity to Inotuzumab Ozogamicin

Germ line genetic NBN variation and predisposition to B-cell acute lymphoblastic leukemia in children

The Impact of Age and Genomics on Drug Sensitivity in 1,076 Children and Adults with B-Cell Acute Lymphoblastic Leukemia

Intensification of Therapy and Pharmacogenetic Personalization Mitigate Racial Disparities in Pediatric Acute Myeloid Leukemia Outcomes

Evaluating Blinatumomab Treatment Adoption in Varied Resource Settings Using the RE-AIM Framework

STAG2/LMO2 Gamma-Delta (γδ) T-ALL: Identification and Characterization of an Extremely High Risk Group of T-ALL in the Very Young

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