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Journal Articles

Outcomes in patients with ETV6::RUNX1 or high-hyperdiploid B-ALL treated in the St. Jude Total Therapy XV/XVI studies

Katelyn Purvis, Yinmei Zhou, Seth E. Karol, Jeffrey E. Rubnitz, Raul C. Ribeiro, Shawn HR Lee, Jun J. Yang, W. Paul Bowman, Lu Wang, Stephanie B Dixon, Kathryn G Roberts, Qingsong Gao, Cheng Cheng, Charles G. Mullighan, Sima Jeha, Ching-Hon Pui, Hiroto Inaba

Blood blood.2024024936.

https://doi.org/10.1182/blood.2024024936

Published: 2024

Includes: Supplemental data

Journal Articles

Germ line genetic NBN variation and predisposition to B-cell acute lymphoblastic leukemia in children

Carolin S. Escherich, Wenan Chen, Yizhen Li, Wenjian Yang, Rina Nishii, Zhenhua Li, Elizabeth A. Raetz, Meenakshi Devidas, Gang Wu, Kim E. Nichols, Hiroto Inaba, Ching-Hon Pui, Sima Jeha, Bruce M. Camitta, Eric Larsen, Stephen P. Hunger, Mignon L. Loh, Jun J. Yang

Blood (2024) 143 (22): 2270–2283.

https://doi.org/10.1182/blood.2023023336

Published: 2024

Includes: Supplemental data

Journal Articles

STAG2/LMO2 Gamma-Delta (γδ) T-ALL: Identification and Characterization of an Extremely High Risk Group of T-ALL in the Very Young

Shunsuke Kimura, Petri Pölönen, Lindsey Montefiori, Kenneth Caldwell, Ilaria Iacobucci, Chelsey Chen, Anthony Brown, Katie Han, Yen-Chun Liu, Yunchao Chang, Zhongshan Cheng, Zhou Yinmei, Chun Shik Park, Sharnise Mitchell, Noemi Reyes, Allen Yeoh, Andishe Attarbaschi, Andrew Moore, Atsushi Manabe, Barbara Buldini, Kean Hui Chiew, Chi Kong Li, Ching-Hon Pui, Chunxu Qu, Daisuke Tomizawa, Elisabeth Paietta, Franco Locatelli, Gabriele Escherich, Gao Qingsong, Hannah Elisa Muhle, Hanne Vibeke Marquart, Hester A. de Groot-Kruseman, Jacob M. Rowe, Jan Stary, Jan Trka, John Kim Choi, Jules P.P. Meijerink, Junko Takita, Katarzyna Pawinska-Wasikowska, Kjeld Schmiegelow, Mariko Eguchi, Martin Schrappe, Martin Zimmermann, Masatoshi Takagi, Melissa Maybury, Michael Svaton, Michaela Reiterova, Michal Kicinski, Motohiro Kato, Orietta Spinelli, Pauline Mazilier, Paul G. Thomas, Riccardo Masetti, Rishi Sury Kotecha, Rob Pieters, Sarah Elitzur, Selina M Luger, Shuhong Shen, Sima Jeha, Steven M. Kornblau, Szymon Skoczen, Takako Miyamura, Tiffaney Vincent, Toshihiko Imamura, Valentino Conter, Yanjing Tang, Zhaohui Gu, Kathryn G. Roberts, David T. Teachey, Kristine R Crews, Cheng Cheng, Jun J. Yang, Hiroto Inaba, Charles G. Mullighan

Blood (2023) 142 (Supplement 1): 845.

https://doi.org/10.1182/blood-2023-178688

Published: 2023

Journal Articles

Zegocractin to Reduce the Severity of Asparaginase Associated Pancreatitis in Children with Acute Lymphoblastic Leukemia: Results of the Phase 1 Portion of the Crspa Study

Seth E. Karol, Haitao Pan, Zhou Yinmei, Jeffrey E. Rubnitz, Nickhill Bhakta, Sima Jeha, Mary V. Relling, Kristine R Crews, John C Panetta, Cara Morin, Cheng Cheng, Ching-Hon Pui, Hiroto Inaba, M Beth McCarville

Blood (2023) 142 (Supplement 1): 2837.

https://doi.org/10.1182/blood-2023-188357

Published: 2023

Journal Articles

The Impact of Age and Genomics on Drug Sensitivity in 1,076 Children and Adults with B-Cell Acute Lymphoblastic Leukemia

Blood (2023) 142 (Supplement 1): 596.

https://doi.org/10.1182/blood-2023-181788

Published: 2023

Journal Articles

Intensification of Therapy and Pharmacogenetic Personalization Mitigate Racial Disparities in Pediatric Acute Myeloid Leukemia Outcomes

Jatinder K. Lamba, Richard J Marrero, Huiyun Wu, Xueyuan Cao, Phani Krishna Parcha, Seth E. Karol, Hiroto Inaba, Dennis John Kuo, Barbara Degar, Kenneth Matthew Heym, Jeffrey Taub, Norman J. Lacayo, Ching-Hon Pui, Raul C. Ribeiro, Stanley Pounds, Jeffrey E. Rubnitz

Blood (2023) 142 (Supplement 1): 386.

https://doi.org/10.1182/blood-2023-173617

Published: 2023

Journal Articles

Evaluating Blinatumomab Treatment Adoption in Varied Resource Settings Using the RE-AIM Framework

Caitlyn Duffy, Zehra Fadoo, Niharendu Ghara, Victor Santana, Hiroto Inaba, Sima Jeha, Yichen Chen, Linh Pham, Hyun Jy Chung, Meenakshi Devidas, Nickhill Bhakta, Heather Brandt

Blood (2023) 142 (Supplement 1): 3713.

https://doi.org/10.1182/blood-2023-190228

Published: 2023

Journal Articles

EBV-driven lymphoid neoplasms associated with pediatric ALL maintenance therapy

Blood (2023) 141 (7): 743–755.

https://doi.org/10.1182/blood.2022016975

Published: 2023

Includes: Supplemental data

Journal Articles

Engineering naturally occurring CD7 − T cells for the immunotherapy of hematological malignancies

Blood (2022) 140 (25): 2684–2696.

https://doi.org/10.1182/blood.2021015020

Published: 2022

Includes: Supplemental data

Journal Articles

Chromatin Accessibility Landscapes of B-Cell Acute Lymphoblastic Leukemia Identify Extensive Epigenomic Reprogramming and Heterogeneity Among Subtypes

Kelly R. Barnett, Jonathan D. Diedrich, Brennan P. Bergeron, Wenjian Yang, Kristine R. Crews, Wendy Stock, Elisabeth Paietta, Steven M. Kornblau, Hiroto Inaba, Sima Jeha, Ching-Hon Pui, Mary V. Relling, William E. Evans, Jun J.J. Yang, Daniel Savic

Blood (2022) 140 (Supplement 1): 5907–5908.

https://doi.org/10.1182/blood-2022-166528

Published: 2022

Journal Articles

Genome-Wide Association Study Identifies Variants Associated with Clinical Outcomes in Pediatric Patients with Newly Diagnosed Acute Myeloid Leukemia

Richard J Marrero, Xueyuan Cao, Huiyun Wu, Hiroto Inaba, Susana C. Raimondi, Ching-Hon Pui, Raul C. Ribeiro, Jeffrey E. Rubnitz, Stanley B. Pounds, Jatinder K. Lamba

Blood (2022) 140 (Supplement 1): 6295–6296.

https://doi.org/10.1182/blood-2022-159534

Published: 2022

Journal Articles

Epigenetic Fine Mapping and Functional Dissection of Inherited Non-Coding Variation Impacting the Pharmacogenomics of Acute Lymphoblastic Leukemia Treatment

Kashi Raj Bhattarai, Kelly R. Barnett, Robert J. Mobley, Daniel C. Ferguson, Jonathan D. Diedrich, Brennan P. Bergeron, Wenjian Yang, Kristine R. Crews, Wendy Stock, Elisabeth Paietta, Steven M. Kornblau, Hiroto Inaba, Sima Jeha, Ching-Hon Pui, Cheng Cheng, Mary V. Relling, William E. Evans, Jun J.J. Yang, Daniel Savic

Blood (2022) 140 (Supplement 1): 3027–3028.

https://doi.org/10.1182/blood-2022-167419

Published: 2022

Journal Articles

Proteomic Analysis Identifies Epigenetic Modifiers and Potential Negative Regulators of Leukemogenesis KMD6A and SETDB1 to be Induced Post In Vivo Decitabine Exposure in Pediatric AML

Jatinder K. Lamba, Xueyuan Cao, Huiyun Wu, Hiroto Inaba, Raul C. Ribeiro, Junmin Peng, Tanja A. Gruber, Jeffrey E. Rubnitz, Stanley B. Pounds

Blood (2022) 140 (Supplement 1): 6086–6087.

https://doi.org/10.1182/blood-2022-166671

Published: 2022

Journal Articles

Pharmacotypes across the Genomic Landscape of Pediatric Acute Lymphoblastic Leukemia and Impact on Treatment Response

Blood (2022) 140 (Supplement 1): 1730–1731.

https://doi.org/10.1182/blood-2022-156699

Published: 2022

Journal Articles

IKZF1 plus Confers a Strong Adverse Prognostic Effect in Total Therapy Studies (XV/XVI)

Ruth Wangondu, Emily Ashcraft, Kathryn G Roberts, Cheng Cheng, Hiroto Inaba, Charles G. Mullighan

Blood (2022) 140 (Supplement 1): 118–120.

https://doi.org/10.1182/blood-2022-158319

Published: 2022

Journal Articles

PAX5 Epigenetically Orchestrates CD58 Transcription and Modulates Blinatumomab Response in Acute Lymphoblastic Leukemia

Yizhen Li, Takaya Moriyama, Satoshi Yoshimura, Xuijie Zhao, Zhenhua LI, Xu Yang, Jacob A Steele, Shondra Miller, Elisabeth Paietta, Marina Konopleva, Jiyang Yu, Hiroto Inaba, Raul C Ribeiro, Ching-Hon Pui, Jun J. Yang

Blood (2022) 140 (Supplement 1): 1041–1042.

https://doi.org/10.1182/blood-2022-156746

Published: 2022

Journal Articles

Personalization of Induction Therapy for Pediatric AML to Ara-C+Dauno+ Etoposide (ADE) or Clofarabine+Ara-C According to a Polygenic Ara-C SNP Score- ACS10

Jatinder K. Lamba, Richard J Marrero, Abdelrahman H Elsayed, Xueyuan Cao, Huiyun Wu, Hiroto Inaba, Susana C. Raimondi, Ching-Hon Pui, Raul C. Ribeiro, Jeffrey E. Rubnitz, Stanley B. Pounds

Blood (2022) 140 (Supplement 1): 1039–1040.

https://doi.org/10.1182/blood-2022-159657

Published: 2022

Journal Articles

Association of unbalanced translocation der(1;7) with germline GATA2 mutations

Blood (2021) 138 (23): 2441–2445.

https://doi.org/10.1182/blood.2021012781

Published: 2021

Includes: Supplemental data

Journal Articles

Integrated Genomic Analysis Identifies UBTF Tandem Duplications As a Subtype-Defining Lesion in Pediatric Acute Myeloid Leukemia

Blood (2021) 138 (Supplement 2): LBA-4.

https://doi.org/10.1182/blood-2021-155134

Published: 2021

Journal Articles

Clofarabine-Based Chemotherapy for KMT2A r Infantile Acute Lymphoblastic Leukemia

Tanja Andrea Gruber, Deqing Pei, John Kim Choi, Cheng Cheng, Elaine Coustan-Smith, Dario Campana, Hope Swanson, Jennifer L Pauley, Hiroto Inaba, Monika Metzger, Jeffrey E. Rubnitz, Raul C Ribeiro, Susana C. Raimondi, William E. Evans, Mary V. Relling, Ching-Hon Pui, Sima Jeha

Blood (2021) 138 (Supplement 1): 3406.

https://doi.org/10.1182/blood-2021-148936

Published: 2021

NARROW

Outcomes in patients with ETV6::RUNX1 or high-hyperdiploid B-ALL treated in the St. Jude Total Therapy XV/XVI studies

Germ line genetic NBN variation and predisposition to B-cell acute lymphoblastic leukemia in children

STAG2/LMO2 Gamma-Delta (γδ) T-ALL: Identification and Characterization of an Extremely High Risk Group of T-ALL in the Very Young

Zegocractin to Reduce the Severity of Asparaginase Associated Pancreatitis in Children with Acute Lymphoblastic Leukemia: Results of the Phase 1 Portion of the Crspa Study

The Impact of Age and Genomics on Drug Sensitivity in 1,076 Children and Adults with B-Cell Acute Lymphoblastic Leukemia

Intensification of Therapy and Pharmacogenetic Personalization Mitigate Racial Disparities in Pediatric Acute Myeloid Leukemia Outcomes

Evaluating Blinatumomab Treatment Adoption in Varied Resource Settings Using the RE-AIM Framework

EBV-driven lymphoid neoplasms associated with pediatric ALL maintenance therapy

Engineering naturally occurring CD7 − T cells for the immunotherapy of hematological malignancies

Chromatin Accessibility Landscapes of B-Cell Acute Lymphoblastic Leukemia Identify Extensive Epigenomic Reprogramming and Heterogeneity Among Subtypes

Genome-Wide Association Study Identifies Variants Associated with Clinical Outcomes in Pediatric Patients with Newly Diagnosed Acute Myeloid Leukemia

Epigenetic Fine Mapping and Functional Dissection of Inherited Non-Coding Variation Impacting the Pharmacogenomics of Acute Lymphoblastic Leukemia Treatment

Proteomic Analysis Identifies Epigenetic Modifiers and Potential Negative Regulators of Leukemogenesis KMD6A and SETDB1 to be Induced Post In Vivo Decitabine Exposure in Pediatric AML

Pharmacotypes across the Genomic Landscape of Pediatric Acute Lymphoblastic Leukemia and Impact on Treatment Response

IKZF1 plus Confers a Strong Adverse Prognostic Effect in Total Therapy Studies (XV/XVI)

PAX5 Epigenetically Orchestrates CD58 Transcription and Modulates Blinatumomab Response in Acute Lymphoblastic Leukemia

Personalization of Induction Therapy for Pediatric AML to Ara-C+Dauno+ Etoposide (ADE) or Clofarabine+Ara-C According to a Polygenic Ara-C SNP Score- ACS10

Association of unbalanced translocation der(1;7) with germline GATA2 mutations

Integrated Genomic Analysis Identifies UBTF Tandem Duplications As a Subtype-Defining Lesion in Pediatric Acute Myeloid Leukemia

Clofarabine-Based Chemotherapy for KMT2A r Infantile Acute Lymphoblastic Leukemia

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American Society of Hematology

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American Society of Hematology

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