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Journal Articles

A novel intercontinental external quality assessment program for flow cytometric measurable residual disease assessment in pediatric AML

Blood (2025) 146 (Supplement 1): 3514.

https://doi.org/10.1182/blood-2025-3514

Published: 2025

Journal Articles

Post-transplant maintenance with sorafenib is safe and effective in pediatric patients with har FLT3/ITD AML: A report from the Children's oncology group protocol AAML1031

Caitlin Elgarten, Todd Alonzo, Robert Gerbing, John Choi, Brian Fisher, Betsy Hirsch, Samir Kahwash, John Levine, Lisa Brodersen, Michael Loken, Susana Raimondi, Katherine Tarlock, Andrew Wood, Lillian Sung, Todd Cooper, Alan Gamis, Soheil Meshinchi, Richard Aplenc, Jessica Pollard

Blood (2025) 146 (Supplement 1): 1644.

https://doi.org/10.1182/blood-2025-1644

Published: 2025

Journal Articles

Optimized treatment for pediatric patients with low-risk Acute Myeloid Leukemia: A report from the Children's oncology group study AAML1831

Reena Pabari, Chana Glasser, Todd Alonzo, Jim Wang, Richard Aplenc, Alan Gamis, Betsy Hirsch, Gordana Raca, Soheil Meshinchi, Kasey Leger, Kelly Getz, Anders Kolb, Jessica Pollard, Sarah Tasian, Matthew Kutny, Todd Cooper

Blood (2025) 146 (Supplement 1): 878.

https://doi.org/10.1182/blood-2025-878

Published: 2025

Journal Articles

Identifying barriers to clinical trial enrollment for children with relapsed or refractory hematologic malignancies

Blood (2025) 146 (Supplement 1): 4404.

https://doi.org/10.1182/blood-2025-4404

Published: 2025

Journal Articles

Etoposide can be safely removed from induction chemotherapy without impacting survival for pediatric acute myeloid leukemia – a report from the Children's oncology group study AAML1831

Jenna Rossoff, Jing Chen, Todd Alonzo, Jim Wang, Richard Aplenc, Alan Gamis, Betsy Hirsch, Gordana Raca, Soheil Meshinchi, Anders Kolb, Sarah Tasian, Jessica Pollard, Matthew Kutny, Todd Cooper

Blood (2025) 146 (Supplement 1): 877.

https://doi.org/10.1182/blood-2025-877

Published: 2025

Journal Articles

Central nervous system disease status significantly impacts survival in pediatric acute myeloid leukemia: A report from Children's Oncology Group study AAML1831

Zachary Graff, Todd Alonzo, Robert Gerbing, Jim Wang, Jessica Pollard, Soheil Meshinchi, Alan Gamis, Richard Aplenc, Betsy Hirsch, Gordana Raca, Todd Cooper, Matthew Kutny

Blood (2025) 146 (Supplement 1): 872.

https://doi.org/10.1182/blood-2025-872

Published: 2025

Journal Articles

NUP98::NSD1 fusion is associated with poor outcomes in Acute Myeloid Leukemia regardless of co-occurring mutations and treatment regimen

Katherine Tarlock, Danielle Kirkey, Rhonda Ries, Jack H. Peplinski, Todd Alonzo, Robert Gerbing, Jim Wang, Todd Cooper, Alan Gamis, Richard Aplenc, Martina Pigazzi, Franco Locatelli, Jessica Pollard, Soheil Meshinchi

Blood (2025) 146 (Supplement 1): 1702.

https://doi.org/10.1182/blood-2025-1702

Published: 2025

Journal Articles

ITCC-101/APAL2020D: A randomized Phase 3 trial of fludarabine/cytarabine/gemtuzumab ozogamycin with or without venetoclax in children with relapsed Acute Myeloid Leukemia

Blood (2025) 146 (Supplement 1): 1656.

https://doi.org/10.1182/blood-2025-1656

Published: 2025

Journal Articles

Feasibility and utility of unmatched whole-genome sequencing (uWGS) for pediatric acute leukemias: An analysis of leukemia precision-based therapy (LEAP) study samples

Blood (2025) 146 (Supplement 1): 2561.

https://doi.org/10.1182/blood-2025-2561

Published: 2025

Journal Articles

FLT3 (CD135) expression in pediatric AML is associated with specific disease characteristics and worse outcome in the setting of sorafenib theraphy: A report from the Children's Oncology Group AAML1031 protocol.

Andrew Menssen, Amenech Ashango, Todd Alonzo, Robert Gerbing, Maria Pardo, Fan-Chi Hsu, Loren Lott, Fangyan Dai, Todd Cooper, Jessica Pollard, Katherine Tarlock, Richard Aplenc, Soheil Meshinchi, Lisa Brodersen, Michael Loken, Chad Hudson

Blood (2025) 146 (Supplement 1): 5256.

https://doi.org/10.1182/blood-2025-5256

Published: 2025

Journal Articles

Clinical, cytogenetic and molecular characteriszation of Mecom- rearranged pediatric de novo Acute Myeloid Leukemia (AML): A retrospective cohort study of the international-berlin-frankfurt-Münster (I-BFM) AML-study group

Blood (2025) 146 (Supplement 1): 1608.

https://doi.org/10.1182/blood-2025-1608

Published: 2025

Journal Articles

Analysis of 3346 patients from the combined Children's Oncology Group AML studies further characterizes RAM immunophenotype AML and reveals other associated phenotypes and genetic drivers.

Andrew Menssen, Jacqueline Cook, Todd Alonzo, Robert Gerbing, Maria Pardo, Fan-Chi Hsu, Loren Lott, Fangyan Dai, Amenech Ashango, Thanh Thanh Dinh, Todd Cooper, Jessica Pollard, Katherine Tarlock, Lisa Brodersen, Michael Loken, Soheil Meshinchi, Chad Hudson

Blood (2025) 146 (Supplement 1): 337.

https://doi.org/10.1182/blood-2025-337

Published: 2025

Journal Articles

Post Hematopoietic Cell Transplantation Maintenance Therapy with Low-Dose Azacitidine in a Pediatric Population with High-Risk Myeloid Neoplasms

Katherine Tarlock, Emily C Merkel, Todd Cooper, Corinne Summers, Monica Thakar, Paul A Carpenter, Aleksandra Petrovic, Ross Goshorn, Robert Irwin, Ted Gooley, Marie Bleakley, Ann Dahlberg

Blood (2023) 142 (Supplement 1): 4956.

https://doi.org/10.1182/blood-2023-181256

Published: 2023

Journal Articles

Leveraging Custom CRISPR/Cas9 Screens to Identify AraC-Daunorubicin-Etoposide (ADE), Gemtuzumab Ozogamicin (GO), and Bortezomib Response Modulators Association with Clinical Outcomes in Pediatric AML

Nam Nguyen, Phani Krishna Parcha, Abderrahmane Tagmount, Bailey Gregory, Jeffrey E. Rubnitz, Raul C. Ribeiro, Xueyuan Cao, Todd A. Alonzo, Richard Aplenc, Alan S Gamis, Todd Cooper, E. Anders Kolb, Soheil Meshinchi, Stanley Pounds, Christopher Vulpe, Jatinder K. Lamba

Blood (2023) 142 (Supplement 1): 1558.

https://doi.org/10.1182/blood-2023-178832

Published: 2023

Journal Articles

Europeanpediatric Acute Leukemia (EuPAL) Registry

Katarzyna Majstrowicz, Katharina Waack, Evangelia Antoniou, Naghmeh Niktoreh, Gwen Nichols, Laura Di Laurenzio, Michele S. Redell, Todd Cooper, E. Anders Kolb, Sarah K. Tasian, Franco Locatelli, C. Michel Zwaan, Dirk Reinhardt

Blood (2023) 142 (Supplement 1): 1496.

https://doi.org/10.1182/blood-2023-189684

Published: 2023

Journal Articles

Establishing Real-World Data-Driven Response Criteria in Pediatric Acute Myeloid Leukemia

Richard Aplenc, Yimei Li, Julianne Ani, Caitlin W. Elgarten, Lisa D'Errico, Todd Cooper, E. Anders Kolb, Maria Monica Gramatges, Meret Henry, Tamara P. Miller, Rajen Mody, Elaine Morgan, Regina M. Myers, Jessica A. Pollard, Alix Seif, Brian T. Fisher, Kelly D. Getz

Blood (2023) 142 (Supplement 1): 726.

https://doi.org/10.1182/blood-2023-185647

Published: 2023

Journal Articles

APAL2020SC Pediatric Acute Leukemia (PedAL) Screening Trial - Developing New Therapies for Relapsed Leukemias

Michele S. Redell, Todd A. Alonzo, Robert Gerbing, Jim Wang, Maureen M. O'Brien, Gwen Nichols, Laura Di Laurenzio, Sarah K. Tasian, C. Michel Zwaan, Dirk Reinhardt, E. Anders Kolb, Todd Cooper

Blood (2023) 142 (Supplement 1): 1492.

https://doi.org/10.1182/blood-2023-190947

Published: 2023

Journal Articles

ACS10- Cytarabine Pharmacogenomics Score Impacts Survival in Pediatric AML Patients Treated on AAML1031 Trial and Associates with Outcome Differences in Black AML Patients

Richard J Marrero, Vivek M. Shastri, Richard Aplenc, Todd Cooper, Todd A. Alonzo, Alan S Gamis, Jim Wang, Soheil Meshinchi, E. Anders Kolb, Jatinder K. Lamba

Blood (2023) 142 (Supplement 1): 4314.

https://doi.org/10.1182/blood-2023-187515

Published: 2023

Journal Articles

Impact of Molecular Risk on Efficacy of Blood and Marrow Transplantation for Pediatric Acute Myeloid Leukemia: A Report from the Children's Oncology Group

Benjamin J Huang, Lauren K. Meyer, Adam Lamble, Jim Wang, Rhonda E Ries, Alan S Gamis, Richard Aplenc, Katherine Tarlock, Todd Cooper, E. Anders Kolb, Todd A. Alonzo, Soheil Meshinchi, Joseph Chewning, William G. Woods, John T. Horan

Blood (2023) 142 (Supplement 1): 655.

https://doi.org/10.1182/blood-2023-186955

Published: 2023

Journal Articles

A Phase 1 Study of Azacitidine (AZA) in Combination with Fludarabine and Cytarabine in Relapse/Refractory Childhood Leukemia: A Therapeutic Advances in Childhood Leukemia & Lymphoma (TACL) Study

Weili Sun, MDPhD, Paul S Gaynon, MD, Richard Sposto, PhD, Henrique Bittencourt, MD, Andrew E. Place, MDPhD, Yoav H Messinger, MD, Chris Fraser, MD, Luciano Dalla-Pozza, MD, Jeannette van der Giessen, BA, CCRP, Elena Eckroth, CCRC, Xiaojing Yang, PhD, Gangning Liang, PhD, Peter A. Jones, PhD DSc, Alan S. Wayne, MD, Todd Cooper, DO

Blood (2014) 124 (21): 3764.

https://doi.org/10.1182/blood.V124.21.3764.3764

Published: 2014

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A novel intercontinental external quality assessment program for flow cytometric measurable residual disease assessment in pediatric AML

Post-transplant maintenance with sorafenib is safe and effective in pediatric patients with har FLT3/ITD AML: A report from the Children's oncology group protocol AAML1031

Optimized treatment for pediatric patients with low-risk Acute Myeloid Leukemia: A report from the Children's oncology group study AAML1831

Identifying barriers to clinical trial enrollment for children with relapsed or refractory hematologic malignancies

Etoposide can be safely removed from induction chemotherapy without impacting survival for pediatric acute myeloid leukemia – a report from the Children's oncology group study AAML1831

Central nervous system disease status significantly impacts survival in pediatric acute myeloid leukemia: A report from Children's Oncology Group study AAML1831

NUP98::NSD1 fusion is associated with poor outcomes in Acute Myeloid Leukemia regardless of co-occurring mutations and treatment regimen

ITCC-101/APAL2020D: A randomized Phase 3 trial of fludarabine/cytarabine/gemtuzumab ozogamycin with or without venetoclax in children with relapsed Acute Myeloid Leukemia

Feasibility and utility of unmatched whole-genome sequencing (uWGS) for pediatric acute leukemias: An analysis of leukemia precision-based therapy (LEAP) study samples

FLT3 (CD135) expression in pediatric AML is associated with specific disease characteristics and worse outcome in the setting of sorafenib theraphy: A report from the Children's Oncology Group AAML1031 protocol.

Clinical, cytogenetic and molecular characteriszation of Mecom- rearranged pediatric de novo Acute Myeloid Leukemia (AML): A retrospective cohort study of the international-berlin-frankfurt-Münster (I-BFM) AML-study group

Analysis of 3346 patients from the combined Children's Oncology Group AML studies further characterizes RAM immunophenotype AML and reveals other associated phenotypes and genetic drivers.

Post Hematopoietic Cell Transplantation Maintenance Therapy with Low-Dose Azacitidine in a Pediatric Population with High-Risk Myeloid Neoplasms

Leveraging Custom CRISPR/Cas9 Screens to Identify AraC-Daunorubicin-Etoposide (ADE), Gemtuzumab Ozogamicin (GO), and Bortezomib Response Modulators Association with Clinical Outcomes in Pediatric AML

Europeanpediatric Acute Leukemia (EuPAL) Registry

Establishing Real-World Data-Driven Response Criteria in Pediatric Acute Myeloid Leukemia

APAL2020SC Pediatric Acute Leukemia (PedAL) Screening Trial - Developing New Therapies for Relapsed Leukemias

ACS10- Cytarabine Pharmacogenomics Score Impacts Survival in Pediatric AML Patients Treated on AAML1031 Trial and Associates with Outcome Differences in Black AML Patients

Impact of Molecular Risk on Efficacy of Blood and Marrow Transplantation for Pediatric Acute Myeloid Leukemia: A Report from the Children's Oncology Group

A Phase 1 Study of Azacitidine (AZA) in Combination with Fludarabine and Cytarabine in Relapse/Refractory Childhood Leukemia: A Therapeutic Advances in Childhood Leukemia & Lymphoma (TACL) Study

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