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Journal Articles

Optimal dosing of vobramitamab duocarmazine, a CD276 (B7-H3) antibody-drug conjugate, leads to durable eradication of Acute Myeloid Leukemia in preclinical xenograft models

Free
Danielle Kirkey, Melia Blankenfeld, Deryk Loo, Isabel Lira, Grace Hawkins, Nika Panahi, Bruce Liu, Rhonda Ries, Jack H. Peplinski, Ezio Bonvini, Stephen Eck, Soheil Meshinchi
Journal: Blood
Blood (2025) 146 (Supplement 1): 5064.
https://doi.org/10.1182/blood-2025-5064
Published: 2025
Journal Articles

Impact of MDS-associated mutations and age on outcomes in NPM1-mutated AML

Free
Vivian Liu, Megan Othus, Rhonda Ries, Jasmine Naru, Era Pogosova-Agadjanyan, Frederick Appelbaum, Lan Beppu, Thomas Chauncey, Harry Erba, John Godwin, Matthew Fitzgibbon, Min Fang, Stanley Lee, Anna Moseley, Jerald Radich, Cheryl Willman, Feinan Wu, Soheil Meshinchi, Derek Stirewalt
Journal: Blood
Blood (2025) 146 (Supplement 1): 6999.
https://doi.org/10.1182/blood-2025-6999
Published: 2025
Journal Articles

NUP98::NSD1 fusion is associated with poor outcomes in Acute Myeloid Leukemia regardless of co-occurring mutations and treatment regimen

Free
Katherine Tarlock, Danielle Kirkey, Rhonda Ries, Jack H. Peplinski, Todd Alonzo, Robert Gerbing, Jim Wang, Todd Cooper, Alan Gamis, Richard Aplenc, Martina Pigazzi, Franco Locatelli, Jessica Pollard, Soheil Meshinchi
Journal: Blood
Blood (2025) 146 (Supplement 1): 1702.
https://doi.org/10.1182/blood-2025-1702
Published: 2025
Journal Articles

Clinical and molecular characterization of pure erythroid leukemias and sarcomas driven by nfia::CBFA2T3

Free
Benjamin Huang, Alexandra McLean Stevens, Aishwarya Ballapuram, Jolene Won, Colin Smith, Julia Kim, Huy Tran, Robia Pautler, Andrew Doan, Ashley Gray, Alexandra Kovach, Alexis Boulter, Katelyn Oranges, Marilyn Li, Xiaotu Ma, Rhonda Ries, Soheil Meshinchi, Richard Aplenc, Gordana Raca, Michele Redell
Journal: Blood
Blood (2025) 146 (Supplement 1): 3510.
https://doi.org/10.1182/blood-2025-3510
Published: 2025
Journal Articles

Novel AML specific splice junction evaluation identifies ubc and DMBT1 as top proteins of clinical and therapeutic relevance in pediatric Acute Myeloid Leukemia

Free
Ryanne Mulligan, Alyssa Obermayer, Xiaotu Ma, Paulo Rodriguez, Stanley Pounds, Rhonda Ries, Soheil Meshinchi, Timothy Shaw, Jatinder Lamba
Journal: Blood
Blood (2025) 146 (Supplement 1): 3497.
https://doi.org/10.1182/blood-2025-3497
Published: 2025
Journal Articles

HMGA1 chromatin regulators drive transcriptional networks governing cell cycle progression, immune escape, and menin-inhibitor resistance in KMT2A-r Acute Myeloid Leukemia

Free
Bailey West, Li Luo, Zanshe Thompson, Yuze Du, Leslie Cope, Joseph Kim, Audrey-Ann Supreme, Faiza Shaik, Isha Maloo, Kathryn Mi, Alison Park, Soheil Meshinchi, Rhonda Ries, Jung-Hyun Kim, Linda Resar
Journal: Blood
Blood (2025) 146 (Supplement 1): 5027.
https://doi.org/10.1182/blood-2025-5027
Published: 2025
Journal Articles

CLEC2A, a validated cancer-specific antigen, is an ideal candidate for immunotherapeutic targeting in KMT2A-rearranged AML

Free
Danielle Kirkey, Corinne Summers, Katherine Tarlock, Benjamin Huang, Grace Hawkins, Nika Panahi, Melia Blankenfeld, Isabel Lira, Bruce Liu, Seungmin Shin, Rhonda Ries, Jack H. Peplinski, Simona Manni, Pamela De Falco, Biagio De Angelis, Concetta Quintarelli, Franco Locatelli, Wei Li, Soheil Meshinchi
Journal: Blood
Blood (2025) 146 (Supplement 1): 4123.
https://doi.org/10.1182/blood-2025-4123
Published: 2025
Journal Articles

TP53 inactivation confers resistance to the menin inhibitor revumenib in Acute Myeloid Leukemia

Free
Jeevitha D'Souza, Camille Leung, Aishwarya Ballapuram, Abigail S. Lin, Alexa Rane Batingana, Adam Lamble, Rhonda Ries, Carolina Morales, Charisa Cottonham, Pranav Gona, Li Fan, Xiaotu Ma, Kevin Shannon, Soheil Meshinchi, Benjamin Braun, Benjamin Huang
Journal: Blood
Blood (2025) 146 (Supplement 1): 3470.
https://doi.org/10.1182/blood-2025-3470
Published: 2025
Journal Articles

Phase I study of FH FOLR1 CAR T for pediatric patients with FOLR1+/CBFA2T3::GLIS2+ relapsed or refractory Acute Myeloid Leukemia

Free
Katherine Tarlock, Corinne Summers, Danielle Kirkey, Rhonda Ries, Maria Pardo, Andrew Menssen, Chad Hudson, Folashade Otegbeye, Lara Kropp, Christy Greene, Stefanie Schmuck, Armenuhi Avanesyan, Concetta Quintarelli, Michael Loken, Franco Locatelli, Soheil Meshinchi
Journal: Blood
Blood (2025) 146 (Supplement 1): 4176.
https://doi.org/10.1182/blood-2025-4176
Published: 2025
Journal Articles

Multi-omic single cell sequencing reveals discordant MRD and mechanisms of relapse in pediatric AML

Free
Cheryl Peretz, Natalia Murad, Rula Gladden, Anushka Walia, Andrew Koh, Elaine Tran, Vanessa Kennedy, Shruti Bhise, Everett Fan, Rhonda Ries, Benjamin Huang, Soheil Meshinchi, Adam Olshen, Scott Furlan, Catherine Smith
Journal: Blood
Blood (2025) 146 (Supplement 1): 348.
https://doi.org/10.1182/blood-2025-348
Published: 2025
Journal Articles

Prevalence, clinical implications and impact of stem cell transplantation in UBTF-TD positive AML

Free
Valeria Ceolin, Rhonda Ries, Jack H. Peplinski, Danielle Kirkey, Manuela Spadea, Vincenzo Apolito, Katherine Tarlock, Grace Hawkins, Melia Blankenfeld, Isabel Lira, Nika Panahi, Bruce Liu, Christian Thiede, Franco Locatelli, Francesco Saglio, Franca Fagioli, Soheil Meshinchi
Journal: Blood
Blood (2025) 146 (Supplement 1): 221.
https://doi.org/10.1182/blood-2025-221
Published: 2025
Journal Articles

TET2 Mutations Are Highly Associated with RUNX1-RUNX1T1 Translocations and NPMc+ in Childhood AML: a Report from Children's Oncology Group AAML03P1, AAML0531 and NCI/COG Target AML Initiative

Free
Matthew A. Kutny, MD, Todd A. Alonzo, PhD, Yi-Cheng Wang, MS, Rhonda Ries, MA, Jason E. Farrar, MD, Jaime M. Guidry Auvil, PhD, Malcolm A. Smith, MD PhD, Daniela S. Gerhard, PhD, Tanja M. Davidsen, PhD, Patee Gesuwan, Leandro C. Hermida, Marco A Marra, PhD, Andrew J. Mungall, PhD, Richard Moore, PhD, William Long, PhD, Yussanne Ma, PhD, Stuart Zong, E. Anders Kolb, MD, Alan S. Gamis, MD MPH, Soheil Meshinchi, MD PhD
Journal: Blood
Blood (2015) 126 (23): 1368.
https://doi.org/10.1182/blood.V126.23.1368.1368
Published: 2015
Journal Articles

Discovery and Functional Validation of Novel Pediatric Specific FLT3 Activating Mutations in Acute Myeloid Leukemia: Results from the COG/NCI Target Initiative

Free
Katherine Tarlock, MD, M. Eva Hansen, Tiffany Hylkema, Rhonda Ries, MA, Jason E. Farrar, MD, Jaime Guidry Auvil, Daniela S. Gerhard, PhD, Malcolm A. Smith, MD PhD, Tanja M. Davidsen, PhD, Patee Gesuwan, Leandro C. Hermida, Marco A Marra, PhD, Andrew J. Mungall, PhD, Karen Mungall, PhD, Yussanne Ma, Stuart Zong, William Long, PhD, Titus Boggon, PhD, Todd A. Alonzo, PhD, E. Anders Kolb, MD, Alan S. Gamis, MD MPH, Soheil Meshinchi, MD PhD
Journal: Blood
Blood (2015) 126 (23): 87.
https://doi.org/10.1182/blood.V126.23.87.87
Published: 2015
Journal Articles

CSF3R Mutations Represent a Novel Therapeutic Target in Pediatric AML with a High Degree of Overlap with CEBPA Mutations: a Report from COG AAML0531 and COG/NCI Target AML Initiative

Free
Julia Elizabeth Maxson, PhD, Rhonda Ries, MA, Yi-Cheng Wang, MS, Robert B. Gerbing, MA, E. Anders Kolb, MD, Sarah L Thompson, Jaime M. Guidry Auvil, PhD, Marco A Marra, PhD, Yussanne Ma, PhD, Stuart Zong, Andrew J. Mungall, PhD, Richard Moore, PhD, William Long, PhD, Patee Gesuwan, Tanja M. Davidsen, PhD, Leandro C. Hermida, Jason E. Farrar, MD, Jerald P. Radich, MD, Malcolm A. Smith, MD PhD, Daniela S. Gerhard, PhD, Alan S. Gamis, MD MPH, Todd A. Alonzo, PhD, Soheil Meshinchi, MD PhD
Journal: Blood
Blood (2015) 126 (23): 174.
https://doi.org/10.1182/blood.V126.23.174.174
Published: 2015
Journal Articles

Association of CD33 Expression Level with Disease Risk-Group Classification and Induction Response In Pediatric AML: A Report From the Children's Oncology Group

Free
Jessica A. Pollard, MD, Todd A. Alonzo, PhD, Robert B. Gerbing, MA, Phoenix A. Ho, MD, Rhonda Ries, MS, Rong Zeng, BS, Kristen L. Miller, BS, Julia Kuhn, BA, Susana C. Raimondi, PhD, Betsy A. Hirsch, PhD, Janet Franklin, MD, MPH, Alan S. Gamis, MD, MPH, Michael R. Loken, PhD, Soheil Meshinchi, MD, PhD
Journal: Blood
Blood (2010) 116 (21): 2732.
https://doi.org/10.1182/blood.V116.21.2732.2732
Published: 2010