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Journal Articles

DNMT3A Mutants Are Enriched in NPMc+ AML and Associated with Adverse Outcome in Childhood AML

Rhonda E Ries, Xiaotu Ma, Claudia Tregnago, Todd A. Alonzo, Jim Wang, Tiffany Hylkema, Benjamin J Huang, Alireza Torabi, Jack H Peplinski, Logan K Wallace, Richard Aplenc, Alan S Gamis, Katherine Tarlock, Franco Locatelli, Martina Pigazzi, Soheil Meshinchi

Blood (2023) 142 (Supplement 1): 4306.

https://doi.org/10.1182/blood-2023-181060

Published: 2023

Journal Articles

Post Hematopoietic Cell Transplantation Maintenance Therapy with Low-Dose Azacitidine in a Pediatric Population with High-Risk Myeloid Neoplasms

Katherine Tarlock, Emily C Merkel, Todd Cooper, Corinne Summers, Monica Thakar, Paul A Carpenter, Aleksandra Petrovic, Ross Goshorn, Robert Irwin, Ted Gooley, Marie Bleakley, Ann Dahlberg

Blood (2023) 142 (Supplement 1): 4956.

https://doi.org/10.1182/blood-2023-181256

Published: 2023

Journal Articles

CLEC2A Is a Novel AML-Restricted Immunotherapeutic Target Enriched in KMT2A-Rearranged Acute Myeloid Leukemia

Danielle C Kirkey, Leila Robinson, Derek Janssens, Margaret G Hines, Tiffany Hylkema, Makia K Manselle, Rhonda E Ries, Jack H Peplinski, Logan K Wallace, Dominik Otto, Katherine Tarlock, Steven Henikoff, Wei Li, Soheil Meshinchi

Blood (2023) 142 (Supplement 1): 290.

https://doi.org/10.1182/blood-2023-188439

Published: 2023

Journal Articles

Impact of Molecular Risk on Efficacy of Blood and Marrow Transplantation for Pediatric Acute Myeloid Leukemia: A Report from the Children's Oncology Group

Benjamin J Huang, Lauren K. Meyer, Adam Lamble, Jim Wang, Rhonda E Ries, Alan S Gamis, Richard Aplenc, Katherine Tarlock, Todd Cooper, E. Anders Kolb, Todd A. Alonzo, Soheil Meshinchi, Joseph Chewning, William G. Woods, John T. Horan

Blood (2023) 142 (Supplement 1): 655.

https://doi.org/10.1182/blood-2023-186955

Published: 2023

Journal Articles

CD33 CAR T-Cells (CD33CART) for Children and Young Adults with Relapsed/Refractory AML: Dose-Escalation Results from a Phase I/II Multicenter Trial

Blood (2023) 142 (Supplement 1): 771.

https://doi.org/10.1182/blood-2023-179667

Published: 2023

Journal Articles

Clinical and Functional Implications of MYC Variants As a New Class of Pathogenic Variants in AML

Danielle C. Kirkey, Xiaoying Wu, Rhonda E. Ries, Tiffany A. Hylkema, Yanling Liu, Pandurang Kolekar, Quang Tran, Alan S. Gamis, Richard Aplenc, Anders E. Kolb, Todd A. Alonzo, Katherine Tarlock, Robert Eisenman, Soheil Meshinchi

Blood (2022) 140 (Supplement 1): 3395–3396.

https://doi.org/10.1182/blood-2022-168469

Published: 2022

Journal Articles

Clinical Outcome and Treatment-Related Mortality in Patients with Acute Myeloid Leukemia Treated at the Uganda Cancer Institute

Clement Dove Okello, Soheil Meshinchi, Katherine Tarlock, Edus H. Warren, Andrea M.H. Towlerton, Henry Ddungu, Yusuf Mulumba, Fadhil Geriga, Jackson Orem, Joyce K. Balagadde

Blood (2022) 140 (Supplement 1): 8940–8941.

https://doi.org/10.1182/blood-2022-165982

Published: 2022

Journal Articles

Significant Improvements in Survival for Patients with t(6;9)(p23;q34)/ DEK-NUP214 in Contemporary Trials with Intensification of Therapy: A Report from the Children's Oncology Group

Katherine Tarlock, Todd A. Alonzo, Robert B. Gerbing, Yi-Cheng Wang, Rhonda E. Ries, Betsy A Hirsch, Beverly Lange, William G. Woods, Todd M. Cooper, Alan S. Gamis, Jessica A. Pollard, Richard Aplenc, Anders E. Kolb, Soheil Meshinchi

Blood (2021) 138 (Supplement 1): 519.

https://doi.org/10.1182/blood-2021-147576

Published: 2021

Journal Articles

Biology and Clinical Implications of Complex Landscape of Cooperating Events in FLT3 -ITD Acute Myeloid Leukemia

Katherine Tarlock, Leila Robinson, Todd A. Alonzo, Robert B. Gerbing, Yi-Cheng Wang, Rhonda E. Ries, Amanda R. Leonti, Jenny L. Smith, Tiffany A. Hylkema, Quy Le, Xiaotu Ma, E. Anders Kolb, Richard Aplenc, Jessica A. Pollard, Soheil Meshinchi

Blood (2021) 138 (Supplement 1): 3454.

https://doi.org/10.1182/blood-2021-153703

Published: 2021

Journal Articles

KMT2A Partial Tandem Duplications ( KMT2A -PTD) Is a Rare, but Recurrent Genomic Event in Childhood AML and Associated with High Rate of Co-Occurring FLT3 Mutations

Danielle C. Kirkey, Katherine Tarlock, Rhonda E. Ries, Yi-Cheng Wang, Amanda R. Leonti, Quy Le, Jenny L. Smith, Leila Robinson, Yanling Liu, Quang Tran, Richard Aplenc, Jessica A. Pollard, Anders E. Kolb, Todd A. Alonzo, Xiaotu Ma, Soheil Meshinchi

Blood (2021) 138 (Supplement 1): 609.

https://doi.org/10.1182/blood-2021-147565

Published: 2021

Journal Articles

CEBPA -bZip mutations are associated with favorable prognosis in de novo AML: a report from the Children’s Oncology Group

Katherine Tarlock, Adam J. Lamble, Yi-Cheng Wang, Robert B. Gerbing, Rhonda E. Ries, Michael R. Loken, Lisa Eidenschink Brodersen, Laura Pardo, Amanda Leonti, Jenny L. Smith, Tiffany A. Hylkema, William G. Woods, Todd M. Cooper, E. Anders Kolb, Alan S. Gamis, Richard Aplenc, Todd A. Alonzo, Soheil Meshinchi

Blood (2021) 138 (13): 1137–1147.

https://doi.org/10.1182/blood.2020009652

Published: 2021

Includes: Supplemental data

Journal Articles

Mesothelin Expression Is Associated with Extramedullary Disease and Promotes In Vivo Leukemic Growth in Acute Myeloid Leukemia

Katherine Tarlock, MD, Todd A. Alonzo, PhD, Robert B. Gerbing, MA, Quy Le, PhD, Thao T. Tang, Darcy Hamill, DO, Anilkumar Gopalakrishnapillai, PhD, Sonali Barwe, PhD MSc, Rhonda E. Ries, MA, Richard Aplenc, MD PhD, Andrew C. Wood, MD, E. Anders Kolb, MD, Soheil Meshinchi, MDPhD

Blood (2020) 136 (Supplement 1): 38–39.

https://doi.org/10.1182/blood-2020-134821

Published: 2020

Journal Articles

Clinical Benefit and Tolerability of Crenolanib in Children with Relapsed Acute Myeloid Leukemia Harboring Treatment Resistant FLT3 ITD and Variant FLT3 TKD Mutations Treated on Compassionate Access

Katherine Tarlock, MD, Soheil Meshinchi, MDPhD, Jeffrey E. Rubnitz, MD, Seth E. Karol, MD, Barbara Spitzer, MD, Amit J. Sabnis, MD, Asif Pathan, PhD RPh, Boo Messahel, MD

Blood (2020) 136 (Supplement 1): 23–24.

https://doi.org/10.1182/blood-2020-140399

Published: 2020

Journal Articles

Characteristics and Prognostic Effects of IDH Mutations across the Age Spectrum in AML: A Collaborative Analysis from COG, SWOG, and ECOG

Blood (2020) 136 (Supplement 1): 31–32.

https://doi.org/10.1182/blood-2020-134211

Published: 2020

Journal Articles

Prognostic impact of CSF3R mutations in favorable risk childhood acute myeloid leukemia

Katherine Tarlock, Todd Alonzo, Yi-Cheng Wang, Robert B. Gerbing, Rhonda E. Ries, Tiffany Hylkema, Jenny L. Smith, Julia E. Maxson, Soheil Meshinchi

Blood (2020) 135 (18): 1603–1606.

https://doi.org/10.1182/blood.2019004179

Published: 2020

Includes: Supplemental data

Journal Articles

Preemptive mitigation of CD19 CAR T-cell cytokine release syndrome without attenuation of antileukemic efficacy

Rebecca A. Gardner, Francesco Ceppi, Julie Rivers, Colleen Annesley, Corinne Summers, Agne Taraseviciute, Juliane Gust, Kasey J. Leger, Katherine Tarlock, Todd M. Cooper, Olivia C. Finney, Hannah Brakke, Daniel H. Li, Julie R. Park, Michael C. Jensen

Blood (2019) 134 (24): 2149–2158.

https://doi.org/10.1182/blood.2019001463

Published: 2019

Includes: Supplemental data

Journal Articles

CD117 Expression Is Associated with Cytogenetic and Molecular Profiles and Outcome in Pediatric Acute Myeloid Leukemia

Katherine Tarlock, MD, Lisa Eidenschink Brodersen, PhD, Todd A. Alonzo, PhD, Yi-Cheng Wang, Robert B. Gerbing, Laura Pardo, Fangyan Dai, Alan S Gamis, MD MPH, Richard Aplenc, MD PhD, Jessica A. Pollard, MD, Michael R. Loken, PhD, Soheil Meshinchi, MD PhD

Blood (2019) 134 (Supplement_1): 2699.

https://doi.org/10.1182/blood-2019-127100

Published: 2019

Journal Articles

Sorafenib in Combination with Standard Chemotherapy for Children with High Allelic Ratio FLT3/ITD+ AML Improves Event-Free Survival and Reduces Relapse Risk: A Report from the Children's Oncology Group Protocol AAML1031

Jessica A. Pollard, MD, Todd A. Alonzo, PhD, Patrick A. Brown, MD, Robert B. Gerbing, Elizabeth Fox, MD, John Kim Choi, MD, Brian T. Fisher, DO, MSCE, Betsy A Hirsch, PhD, Samir Kahwash, MD, John E. Levine, MDMS, Michael R. Loken, PhD, Susana C. Raimondi, PhD, Katherine Tarlock, MD, Andrew C. Wood, MBCHB, Lillian Sung, MD PhD, Anders E. Kolb, MD, Alan S Gamis, MD MPH, Soheil Meshinchi, MD PhD, Richard Aplenc, MD PhD

Blood (2019) 134 (Supplement_1): 292.

https://doi.org/10.1182/blood-2019-129557

Published: 2019

Journal Articles

Response to Sorafenib in FLT3 /ITD AML Is Depedent on Co-Occurring Mutational Profile

Katherine Tarlock, MD, Jessica A. Pollard, MD, Todd A. Alonzo, PhD, Robert B. Gerbing, Yi-Cheng Wang, Rhonda E. Ries, MA, Jenny L. Smith, MSc, MD, E. Anders Kolb, MD, Alan S Gamis, MD MPH, Richard Aplenc, MD PhD, Soheil Meshinchi, MD PhD

Blood (2019) 134 (Supplement_1): 119.

https://doi.org/10.1182/blood-2019-127569

Published: 2019

Journal Articles

Somatic Bzip Mutations of CEBPA Are Associated with Favorable Outcome Regardless of Presence As Single Vs. Double Mutation

Katherine Tarlock, MD, Todd A. Alonzo, PhD, Yi-Cheng Wang, Robert B. Gerbing, Rhonda E. Ries, MA, Tiffany A. Hylkema, BS, William G. Woods, MD, Todd M Cooper, DO, Alan S Gamis, MD MPH, Richard Aplenc, MD PhD, Soheil Meshinchi, MD PhD

Blood (2019) 134 (Supplement_1): 181.

https://doi.org/10.1182/blood-2019-126273

Published: 2019

NARROW

DNMT3A Mutants Are Enriched in NPMc+ AML and Associated with Adverse Outcome in Childhood AML

Post Hematopoietic Cell Transplantation Maintenance Therapy with Low-Dose Azacitidine in a Pediatric Population with High-Risk Myeloid Neoplasms

CLEC2A Is a Novel AML-Restricted Immunotherapeutic Target Enriched in KMT2A-Rearranged Acute Myeloid Leukemia

Impact of Molecular Risk on Efficacy of Blood and Marrow Transplantation for Pediatric Acute Myeloid Leukemia: A Report from the Children's Oncology Group

CD33 CAR T-Cells (CD33CART) for Children and Young Adults with Relapsed/Refractory AML: Dose-Escalation Results from a Phase I/II Multicenter Trial

Clinical and Functional Implications of MYC Variants As a New Class of Pathogenic Variants in AML

Clinical Outcome and Treatment-Related Mortality in Patients with Acute Myeloid Leukemia Treated at the Uganda Cancer Institute

Significant Improvements in Survival for Patients with t(6;9)(p23;q34)/ DEK-NUP214 in Contemporary Trials with Intensification of Therapy: A Report from the Children's Oncology Group

Biology and Clinical Implications of Complex Landscape of Cooperating Events in FLT3 -ITD Acute Myeloid Leukemia

KMT2A Partial Tandem Duplications ( KMT2A -PTD) Is a Rare, but Recurrent Genomic Event in Childhood AML and Associated with High Rate of Co-Occurring FLT3 Mutations

CEBPA -bZip mutations are associated with favorable prognosis in de novo AML: a report from the Children’s Oncology Group

Mesothelin Expression Is Associated with Extramedullary Disease and Promotes In Vivo Leukemic Growth in Acute Myeloid Leukemia

Clinical Benefit and Tolerability of Crenolanib in Children with Relapsed Acute Myeloid Leukemia Harboring Treatment Resistant FLT3 ITD and Variant FLT3 TKD Mutations Treated on Compassionate Access

Characteristics and Prognostic Effects of IDH Mutations across the Age Spectrum in AML: A Collaborative Analysis from COG, SWOG, and ECOG

Prognostic impact of CSF3R mutations in favorable risk childhood acute myeloid leukemia

Preemptive mitigation of CD19 CAR T-cell cytokine release syndrome without attenuation of antileukemic efficacy

CD117 Expression Is Associated with Cytogenetic and Molecular Profiles and Outcome in Pediatric Acute Myeloid Leukemia

Sorafenib in Combination with Standard Chemotherapy for Children with High Allelic Ratio FLT3/ITD+ AML Improves Event-Free Survival and Reduces Relapse Risk: A Report from the Children's Oncology Group Protocol AAML1031

Response to Sorafenib in FLT3 /ITD AML Is Depedent on Co-Occurring Mutational Profile

Somatic Bzip Mutations of CEBPA Are Associated with Favorable Outcome Regardless of Presence As Single Vs. Double Mutation

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American Society of Hematology

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American Society of Hematology

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