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Journal Articles

CREBBP alterations are associated with a poor prognosis in de novo AML

Adam J. Lamble, Kohei Hagiwara, Robert B. Gerbing, Jenny L. Smith, Pandurang Kolekar, Rhonda E. Ries, Edward A. Kolb, Todd A. Alonzo, Xiaotu Ma, Soheil Meshinchi

Blood (2023) 141 (17): 2156–2159.

https://doi.org/10.1182/blood.2022017545

Published: 2023

Includes: Supplemental data

Journal Articles

Transcriptome Analysis and Machine Learning Prioritize Therapeutic Strategies for High-Risk Pediatric AML Patients of the KMT2A-Fusion Subgroup

Alyssa Obermayer, Sijie Yao, Jenny L. Smith, Rhonda E. Ries, Yi-Cheng Wang, Jason E Farrar, Scott N Furlan, Tim Triche, Xiaotu Ma, Benjamin J. Huang, Xuefeng Wang, Soheil Meshinchi, Timothy I. Shaw

Blood (2022) 140 (Supplement 1): 3385–3386.

https://doi.org/10.1182/blood-2022-163616

Published: 2022

Journal Articles

A Robust Long Non-Coding RNA Expression Classifier for Risk Stratification in Pediatric AML

Jason E Farrar, Jenny L. Smith, Megan Othus, Benjamin J. Huang, Yi-Cheng Wang, Rhonda E. Ries, Tiffany A. Hylkema, Era L Pogosova-Agadjanyan, Sneha Challa, Amanda R. Leonti, Timothy I. Shaw, Timothy Junius Triche, Jr., Alan S. Gamis, Richard Aplenc, Anders E. Kolb, Xiaotu Ma, Derek Stirewalt, Todd A. Alonzo, Soheil Meshinchi

Blood (2022) 140 (Supplement 1): 9173–9174.

https://doi.org/10.1182/blood-2022-168296

Published: 2022

Journal Articles

Integrated Genomic Analysis Identifies UBTF Tandem Duplications As a Subtype-Defining Lesion in Pediatric Acute Myeloid Leukemia

Blood (2021) 138 (Supplement 2): LBA-4.

https://doi.org/10.1182/blood-2021-155134

Published: 2021

Journal Articles

Integrated Transcriptomics and Proteomics Identifies Therapeutic Targets in Pediatric Acute Myeloid Leukemia

Benjamin J. Huang, Jenny L. Smith, Timothy I. Shaw, Scott N Furlan, Rhonda E. Ries, Amanda R. Leonti, Erin Lynn Crowgey, Lisa Wei, Jason E Farrar, Tim Triche, Xiaotu Ma, Quy Le, Soheil Meshinchi

Blood (2021) 138 (Supplement 1): 1296.

https://doi.org/10.1182/blood-2021-153970

Published: 2021

Journal Articles

Epigenetically Enhanced MED12L in ETO2-GLIS2 Positive Pediatric Acute Megakaryoblastic Leukemia Is Associated with Resistance to the CDK8 Inhibitors

Samrat Roy Choudhury, Jordan T Bird, Stephanie Byrum, Dane Jester, Troy Davidson, Giselle Almeida Gonzalez, David Becton, Jenny L. Smith, Rhonda E. Ries, Soheil Meshinchi, Jason E Farrar

Blood (2021) 138 (Supplement 1): 2208.

https://doi.org/10.1182/blood-2021-148574

Published: 2021

Journal Articles

ETS Family Transcription Factor Fusions in Childhood AML: Distinct Expression Networks and Clinical Implications

Jenny L. Smith, Rhonda E. Ries, Yi-Cheng Wang, Amanda R. Leonti, Todd A. Alonzo, Alan S. Gamis, Richard Aplenc, Anders E. Kolb, Benjamin J. Huang, Xiaotu Ma, Timothy I. Shaw, Soheil Meshinchi

Blood (2021) 138 (Supplement 1): 2356.

https://doi.org/10.1182/blood-2021-148894

Published: 2021

Journal Articles

Epigenetic Silencing of CD34 in AML and Association with Outcome in KMT2A Fusions

Rhonda E. Ries, Lisa Eidenschink Brodersen, Laura Pardo, Timothy Junius Triche, Jr., Amanda R. Leonti, Jenny L. Smith, Todd A. Alonzo, Jason E Farrar, Yi-Cheng Wang, Alice Dang, Alan S. Gamis, Richard Aplenc, E. Anders Kolb, Michael R. Loken, Soheil Meshinchi

Blood (2021) 138 (Supplement 1): 802.

https://doi.org/10.1182/blood-2021-149210

Published: 2021

Journal Articles

Targeting FOLR1 in High-Risk CBF2AT3-GLIS2 AML with Stro-002 FOLR1-Directed Antibody-Drug Conjugate

Quy Le, Jenny L. Smith, Thao T. Tang, Sommer Castro, Cynthia Nourigat-Mckay, LaKeisha Perkins, Benjamin J. Huang, Rhonda E. Ries, Amanda R. Leonti, Tiffany A. Hylkema, Laura Pardo, Cristina Abrahams, Kristin Bedard, Arturo Molina, Lisa Eidenschink Brodersen, Michael R. Loken, Soheil Meshinchi

Blood (2021) 138 (Supplement 1): 209.

https://doi.org/10.1182/blood-2021-153076

Published: 2021

Journal Articles

EZH2-Mediated MHC Class II Silencing Drives Immune Evasion in AML with t(16;21) ( FUS-ERG)

Nate J Buteyn, Connor G Burke, Jenny L. Smith, Rhonda E. Ries, Amanda R. Leonti, Timothy I. Shaw, Benjamin J. Huang, Todd A. Alonzo, Scott N. Furlan, Jason E Farrar, Soheil Meshinchi, Timothy Junius Triche, Jr.

Blood (2021) 138 (Supplement 1): 374.

https://doi.org/10.1182/blood-2021-153256

Published: 2021

Journal Articles

Endothelial Cell Niche Promotes Leukemic Transformation of Human Cord Blood Stem/Progenitor Cells Expressing CBFA2T3-GLIS2 Oncogenic Fusion

Quy Le, Tiffany A. Hylkema, Sommer Castro, Jenny L. Smith, Amanda R. Leonti, Thao T. Tang, Cynthia Nourigat-Mckay, LaKeisha Perkins, Laura Pardo, Lisa Eidenschink Brodersen, Michael R. Loken, Rhonda E. Ries, Keith R. Loeb, Soheil Meshinchi

Blood (2021) 138 (Supplement 1): 360.

https://doi.org/10.1182/blood-2021-148916

Published: 2021

Journal Articles

Therapeutic Targeting of CD74 with STRO-001 Antibody-Drug Conjugate in AML and ALL

Quy Le, Amanda R. Leonti, Thao T. Tang, Sommer Castro, Cynthia Nourigat-Mckay, LaKeisha Perkins, Rhonda E. Ries, Jenny L. Smith, Tiffany A. Hylkema, Laura Pardo, Cristina Abrahams, Kristin Bedard, Arturo Molina, Lisa Eidenschink Brodersen, Michael R. Loken, Soheil Meshinchi

Blood (2021) 138 (Supplement 1): 509.

https://doi.org/10.1182/blood-2021-151160

Published: 2021

Journal Articles

Crebbp Alterations Are Associated with a Poor Prognosis in De Novo AML

Adam J. Lamble, Robert B. Gerbing, Jenny L. Smith, Rhonda E. Ries, Edward A. Kolb, Todd A. Alonzo, Soheil Meshinchi

Blood (2021) 138 (Supplement 1): 3451.

https://doi.org/10.1182/blood-2021-154052

Published: 2021

Journal Articles

Project Stella: Development and Preclinical Assessment of FOLR1-Directed Chimeric Antigen Receptor T Cells in CBF2AT3-GLIS2/RAM AML

Quy Le, Sommer Castro, Thao T. Tang, Cynthia Nourigat-Mckay, LaKeisha Perkins, Tiffany A. Hylkema, Laura Pardo, Jenny L. Smith, Amanda R. Leonti, Rhonda E. Ries, Lisa Eidenschink Brodersen, Michael R. Loken, Soheil Meshinchi

Blood (2021) 138 (Supplement 1): 2788.

https://doi.org/10.1182/blood-2021-151836

Published: 2021

Journal Articles

KMT2A Partial Tandem Duplications ( KMT2A -PTD) Is a Rare, but Recurrent Genomic Event in Childhood AML and Associated with High Rate of Co-Occurring FLT3 Mutations

Danielle C. Kirkey, Katherine Tarlock, Rhonda E. Ries, Yi-Cheng Wang, Amanda R. Leonti, Quy Le, Jenny L. Smith, Leila Robinson, Yanling Liu, Quang Tran, Richard Aplenc, Jessica A. Pollard, Anders E. Kolb, Todd A. Alonzo, Xiaotu Ma, Soheil Meshinchi

Blood (2021) 138 (Supplement 1): 609.

https://doi.org/10.1182/blood-2021-147565

Published: 2021

Journal Articles

Biology and Clinical Implications of Complex Landscape of Cooperating Events in FLT3 -ITD Acute Myeloid Leukemia

Katherine Tarlock, Leila Robinson, Todd A. Alonzo, Robert B. Gerbing, Yi-Cheng Wang, Rhonda E. Ries, Amanda R. Leonti, Jenny L. Smith, Tiffany A. Hylkema, Quy Le, Xiaotu Ma, E. Anders Kolb, Richard Aplenc, Jessica A. Pollard, Soheil Meshinchi

Blood (2021) 138 (Supplement 1): 3454.

https://doi.org/10.1182/blood-2021-153703

Published: 2021

Journal Articles

CEBPA -bZip mutations are associated with favorable prognosis in de novo AML: a report from the Children’s Oncology Group

Katherine Tarlock, Adam J. Lamble, Yi-Cheng Wang, Robert B. Gerbing, Rhonda E. Ries, Michael R. Loken, Lisa Eidenschink Brodersen, Laura Pardo, Amanda Leonti, Jenny L. Smith, Tiffany A. Hylkema, William G. Woods, Todd M. Cooper, E. Anders Kolb, Alan S. Gamis, Richard Aplenc, Todd A. Alonzo, Soheil Meshinchi

Blood (2021) 138 (13): 1137–1147.

https://doi.org/10.1182/blood.2020009652

Published: 2021

Includes: Supplemental data

Journal Articles

Integrative Analysis of Single-Cell RNA-Seq and ATAC-Seq Data across Treatment Time Points in Pediatric AML

Lisa Wei, BS, Diane Trinh, Rhonda E. Ries, MA, Dan Jin, PhD, Richard D. Corbett, Jenny L. Smith, MSc, MD, Scott N. Furlan, MD, Soheil Meshinchi, MDPhD, Marco A. Marra, PhD

Blood (2020) 136 (Supplement 1): 29.

https://doi.org/10.1182/blood-2020-140473

Published: 2020

Journal Articles

Genome and Transcriptome Profiling of Monosomy 7 AML Defines Novel Risk and Therapeutic Cohorts

Blood (2020) 136 (Supplement 1): 20–21.

https://doi.org/10.1182/blood-2020-137244

Published: 2020

Journal Articles

Integrated Stem Cell Signature and Cytomolecular Risk Determination in Pediatric Acute Myeloid Leukemia

Benjamin J. Huang, MD, Jenny L. Smith, MSc, MD, Rhonda E. Ries, MA, Amanda R. Leonti, MS, Erin Lynn Crowgey, PhD, Scott N. Furlan, MD, Timothy Shaw, PhD, Lisa Wei, BS, Yi-Cheng Wang, MS, Robert B. Gerbing, MA, Todd A. Alonzo, PhD, Todd M. Cooper, DO, Edward A. Kolb, MD, Xiaotu Ma, PhD, Jason E. Farrar, MD, Timothy Junius Triche, Jr., PhD, Soheil Meshinchi, MDPhD

Blood (2020) 136 (Supplement 1): 28–29.

https://doi.org/10.1182/blood-2020-142638

Published: 2020

NARROW

CREBBP alterations are associated with a poor prognosis in de novo AML

Transcriptome Analysis and Machine Learning Prioritize Therapeutic Strategies for High-Risk Pediatric AML Patients of the KMT2A-Fusion Subgroup

A Robust Long Non-Coding RNA Expression Classifier for Risk Stratification in Pediatric AML

Integrated Genomic Analysis Identifies UBTF Tandem Duplications As a Subtype-Defining Lesion in Pediatric Acute Myeloid Leukemia

Integrated Transcriptomics and Proteomics Identifies Therapeutic Targets in Pediatric Acute Myeloid Leukemia

Epigenetically Enhanced MED12L in ETO2-GLIS2 Positive Pediatric Acute Megakaryoblastic Leukemia Is Associated with Resistance to the CDK8 Inhibitors

ETS Family Transcription Factor Fusions in Childhood AML: Distinct Expression Networks and Clinical Implications

Epigenetic Silencing of CD34 in AML and Association with Outcome in KMT2A Fusions

Targeting FOLR1 in High-Risk CBF2AT3-GLIS2 AML with Stro-002 FOLR1-Directed Antibody-Drug Conjugate

EZH2-Mediated MHC Class II Silencing Drives Immune Evasion in AML with t(16;21) ( FUS-ERG)

Endothelial Cell Niche Promotes Leukemic Transformation of Human Cord Blood Stem/Progenitor Cells Expressing CBFA2T3-GLIS2 Oncogenic Fusion

Therapeutic Targeting of CD74 with STRO-001 Antibody-Drug Conjugate in AML and ALL

Crebbp Alterations Are Associated with a Poor Prognosis in De Novo AML

Project Stella: Development and Preclinical Assessment of FOLR1-Directed Chimeric Antigen Receptor T Cells in CBF2AT3-GLIS2/RAM AML

KMT2A Partial Tandem Duplications ( KMT2A -PTD) Is a Rare, but Recurrent Genomic Event in Childhood AML and Associated with High Rate of Co-Occurring FLT3 Mutations

Biology and Clinical Implications of Complex Landscape of Cooperating Events in FLT3 -ITD Acute Myeloid Leukemia

CEBPA -bZip mutations are associated with favorable prognosis in de novo AML: a report from the Children’s Oncology Group

Integrative Analysis of Single-Cell RNA-Seq and ATAC-Seq Data across Treatment Time Points in Pediatric AML

Genome and Transcriptome Profiling of Monosomy 7 AML Defines Novel Risk and Therapeutic Cohorts

Integrated Stem Cell Signature and Cytomolecular Risk Determination in Pediatric Acute Myeloid Leukemia

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American Society of Hematology

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American Society of Hematology

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