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Scott N. Furlan
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Journal Articles

HA-1–targeted T-cell receptor T-cell therapy for recurrent leukemia after hematopoietic stem cell transplantation

Clinical Trials & Observations
Elizabeth F. Krakow, Michelle Brault, Corinne Summers, Tanya M. Cunningham, Melinda A. Biernacki, R. Graeme Black, Kyle B. Woodward, Nicole Vartanian, Sami B. Kanaan, Albert C. Yeh, Robson G. Dossa, Merav Bar, Ryan D. Cassaday, Ann Dahlberg, Brian G. Till, Andrew E. Denker, Cecilia C. S. Yeung, Ted A. Gooley, David G. Maloney, Stanley R. Riddell, Philip D. Greenberg, Aude G. Chapuis, Evan W. Newell, Scott N. Furlan, Marie Bleakley
Journal: Blood
Blood (2024) 144 (10): 1069–1082.
https://doi.org/10.1182/blood.2024024105
Published: 2024
Includes: Supplemental data
Journal Articles

CSF1R inhibition promotes neuroinflammation and behavioral deficits during graft-versus-host disease in mice

Rachael C. Adams, Dylan Carter-Cusack, Genesis T. Llanes, Christopher R. Hunter, Janaki Manoja Vinnakota, Marc J. Ruitenberg, Jana Vukovic, Patrick Bertolino, Kirat K. Chand, Julie A. Wixey, Samuel P. Nayler, Geoffrey R. Hill, Scott N. Furlan, Robert Zeiser, Kelli P. A. MacDonald
Journal: Blood
Blood (2024) 143 (10): 912–929.
https://doi.org/10.1182/blood.2023022040
Published: 2024
Includes: Supplemental data
Journal Articles

Microbiota-Specific T Cells Contribute to Graft-Versus-Host Disease after Allogeneic Stem Cell Transplantation

Albert C Yeh, Motoko Koyama, Olivia Waltner, Simone A Minnie, Julie Boiko, Tamer B Shabaneh, Shuichiro Takahashi, Ping Zhang, Kathleen Ensbey, Christine Schmidt, Samuel Legg, Tomoko Sekiguchi, Ethan Nelson, Shruti Bhise, Andrew Stevens, Tracy A Goodpaster, Saranya R. Chakka, Scott N. Furlan, Kate A. Markey, Marie Bleakley, Charles O Elson, III, Geoffrey R Hill
Journal: Blood
Blood (2023) 142 (Supplement 1): 345.
https://doi.org/10.1182/blood-2023-178773
Published: 2023
Journal Articles

Identifying a Relapse Signature in CBFB-MYH11 Acute Myeloid Leukemia

Jack H Peplinski, Logan K Wallace, Rhonda E Ries, Benjamin J Huang, Amanda R Leonti, Danielle C Kirkey, Xiaotu Ma, Scott N Furlan, Soheil Meshinchi
Journal: Blood
Blood (2023) 142 (Supplement 1): 2955.
https://doi.org/10.1182/blood-2023-187637
Published: 2023
Journal Articles

CSF1R Inhibition Promotes Neuroinflammation and Behavioural Deficits during Graft-Versus-Host Disease in Mice

Rachael C Adams, Dylan Carter-Cusack, Genesis T Llanes, Christopher R Hunter, Janaki Manoja Vinnakota, Marc Ruitenberg, Jana Vukovic, Patrick Bertolino, Kirat K. Chand, Julie A. Wixey, Samuel P Nayler, Geoffrey R Hill, Scott N Furlan, Robert Zeiser, Kelli PA MacDonald
Journal: Blood
Blood (2023) 142 (Supplement 1): 2052.
https://doi.org/10.1182/blood-2023-184841
Published: 2023
Journal Articles

Identification of a Relapse Signature in t(8;21) Pediatric AML

Logan K Wallace, Jack H Peplinski, Rhonda E Ries, Benjamin J Huang, Xiaotu Ma, Scott N Furlan, Danielle C Kirkey, Soheil Meshinchi
Journal: Blood
Blood (2023) 142 (Supplement 1): 4318.
https://doi.org/10.1182/blood-2023-189817
Published: 2023
Journal Articles

NOTCH1 signaling during CD4 + T-cell activation alters transcription factor networks and enhances antigen responsiveness

Alec B. Wilkens, Elena C. Fulton, Margot J. Pont, Gabriel O. Cole, Isabel Leung, Sylvia M. Stull, Matthew R. Hart, Irwin D. Bernstein, Scott N. Furlan, Stanley R. Riddell
Journal: Blood
Blood (2022) 140 (21): 2261–2275.
https://doi.org/10.1182/blood.2021015144
Published: 2022
Includes: Supplemental data
Journal Articles

Transcriptome Analysis and Machine Learning Prioritize Therapeutic Strategies for High-Risk Pediatric AML Patients of the KMT2A-Fusion Subgroup

Alyssa Obermayer, Sijie Yao, Jenny L. Smith, Rhonda E. Ries, Yi-Cheng Wang, Jason E Farrar, Scott N Furlan, Tim Triche, Xiaotu Ma, Benjamin J. Huang, Xuefeng Wang, Soheil Meshinchi, Timothy I. Shaw
Journal: Blood
Blood (2022) 140 (Supplement 1): 3385–3386.
https://doi.org/10.1182/blood-2022-163616
Published: 2022
Journal Articles

Single-Cell Multiomics of Pre- and Post- Remission Bone Marrow from a Pediatric Patient with JMML Reveal Distinct Progenitors and Inflammatory Monocytes Which Are Eliminated By Chemotherapy

Rula Green Gladden, Shruti Bhise, Sami B Kanaan, Olivia Waltner, Jeffrey Stevens, Colleen Annesley, Scott N Furlan
Journal: Blood
Blood (2022) 140 (Supplement 1): 7850–7851.
https://doi.org/10.1182/blood-2022-171202
Published: 2022
Journal Articles

Single-Cell Multiomics for Residual Disease Detection in Acute Myelogenous Leukemia after Allogeneic Hematopoietic Cell Transplantation

Melinda Ann Biernacki, Olivia Waltner, Sami B Kanaan, Rula Green Gladden, Shruti Bhise, Todd M. Cooper, Monica Thakar, Soheil Meshinchi, Marie Bleakley, Xueyan Chen, Scott N Furlan
Journal: Blood
Blood (2022) 140 (Supplement 1): 10215–10216.
https://doi.org/10.1182/blood-2022-171164
Published: 2022
Journal Articles

Integrated Transcriptomics and Proteomics Identifies Therapeutic Targets in Pediatric Acute Myeloid Leukemia

Benjamin J. Huang, Jenny L. Smith, Timothy I. Shaw, Scott N Furlan, Rhonda E. Ries, Amanda R. Leonti, Erin Lynn Crowgey, Lisa Wei, Jason E Farrar, Tim Triche, Xiaotu Ma, Quy Le, Soheil Meshinchi
Journal: Blood
Blood (2021) 138 (Supplement 1): 1296.
https://doi.org/10.1182/blood-2021-153970
Published: 2021
Journal Articles

Single-Cell Transcriptomics for Residual Disease Detection in Acute Myelogenous Leukemia Post Allogeneic Hematopoietic Cell Transplantation

Sami B Kanaan, Shruti Bhise, Todd M. Cooper, Soheil Meshinchi, Scott N Furlan
Journal: Blood
Blood (2021) 138 (Supplement 1): 518.
https://doi.org/10.1182/blood-2021-151504
Published: 2021
Journal Articles

Functional Consequence and Therapeutic Targeting of Cryptic ALK Fusions (ALK fus ) in Monosomy7 AML

Makia K. Manselle, Tiffany A. Hylkema, Amanda R. Leonti, Rhonda E. Ries, Quy Le, Scott N Furlan, Soheil Meshinchi
Journal: Blood
Blood (2021) 138 (Supplement 1): 2357.
https://doi.org/10.1182/blood-2021-148179
Published: 2021
Journal Articles

EZH2-Mediated MHC Class II Silencing Drives Immune Evasion in AML with t(16;21) ( FUS-ERG)

Nate J Buteyn, Connor G Burke, Jenny L. Smith, Rhonda E. Ries, Amanda R. Leonti, Timothy I. Shaw, Benjamin J. Huang, Todd A. Alonzo, Scott N. Furlan, Jason E Farrar, Soheil Meshinchi, Timothy Junius Triche, Jr.
Journal: Blood
Blood (2021) 138 (Supplement 1): 374.
https://doi.org/10.1182/blood-2021-153256
Published: 2021
Journal Articles

Repurposing a novel anti-cancer RXR agonist to attenuate murine acute GVHD and maintain graft-versus-leukemia responses

Govindarajan Thangavelu, Chao Wang, Michael Loschi, Asim Saha, Mark J. Osborn, Scott N. Furlan, Kazutoshi Aoyama, Cameron McDonald-Hyman, Ethan G. Aguilar, Amanda S. Janesick, Roshantha A. Chandraratna, Yosef Refaeli, Angela Panoskaltsis-Mortari, Kelli P. MacDonald, Geoffrey R. Hill, Robert Zeiser, Ivan Maillard, Jonathan S. Serody, William J. Murphy, David H. Munn, Bruce Blumberg, Chrysothemis Brown, Vijay Kuchroo, Leslie S. Kean, Keli L. Hippen, Randolph J. Noelle, Bruce R. Blazar
Journal: Blood
Blood (2021) 137 (8): 1090–1103.
https://doi.org/10.1182/blood.2020005628
Published: 2021
Includes: Supplemental data
Journal Articles

Integrative Analysis of Single-Cell RNA-Seq and ATAC-Seq Data across Treatment Time Points in Pediatric AML

Lisa Wei, BS, Diane Trinh, Rhonda E. Ries, MA, Dan Jin, PhD, Richard D. Corbett, Jenny L. Smith, MSc, MD, Scott N. Furlan, MD, Soheil Meshinchi, MDPhD, Marco A. Marra, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 29.
https://doi.org/10.1182/blood-2020-140473
Published: 2020
Journal Articles

The Transcriptomic Landscape of NUP98-Rearranged Pediatric Acute Myeloid Leukemia

Jenny L. Smith, MSc, MD, Eline J.M. Bertrums, Rhonda E. Ries, MA, Fabiana Ostronoff, MD, Amanda R. Leonti, MS, Scott N. Furlan, MD, Bianca F. Goemans, MD PhD, Soheil Meshinchi, MDPhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 36–37.
https://doi.org/10.1182/blood-2020-138935
Published: 2020
Journal Articles

Integrated Stem Cell Signature and Cytomolecular Risk Determination in Pediatric Acute Myeloid Leukemia

Benjamin J. Huang, MD, Jenny L. Smith, MSc, MD, Rhonda E. Ries, MA, Amanda R. Leonti, MS, Erin Lynn Crowgey, PhD, Scott N. Furlan, MD, Timothy Shaw, PhD, Lisa Wei, BS, Yi-Cheng Wang, MS, Robert B. Gerbing, MA, Todd A. Alonzo, PhD, Todd M. Cooper, DO, Edward A. Kolb, MD, Xiaotu Ma, PhD, Jason E. Farrar, MD, Timothy Junius Triche, Jr., PhD, Soheil Meshinchi, MDPhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 28–29.
https://doi.org/10.1182/blood-2020-142638
Published: 2020
Journal Articles

IL2 and Rapamycin Enhance Persistence of Adoptively-Transferred Ex-Vivo Expanded T Regulatory Cells

Scott N Furlan, MD, Christina Lopez, PhD, Victor Tkachev, PhD, Kayla Betz, Daniel J Hunt, James Hibbard, PhD, Bruce R. Blazar, MD, Cole Trapnell, PhD, Leslie Kean, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2049.
https://doi.org/10.1182/blood-2018-99-120254
Published: 2018
Journal Articles

Pharmacologic Blockade of Notch/Delta-like Ligand 4 Signaling Protects from Gastrointestinal Acute Graft-Versus-Host Disease in Non-Human Primates

Victor Tkachev, PhD, Frank Kuhnert, PhD, Scott N Furlan, MD, Hengqi Zheng, MD, Daniel J Hunt, Lucrezia Colonna, PhD, Judith M Carlson, BS, Agne Taraseviciute, MD PhD, Angela Panoskaltsis-Mortari, PhD, Virginia Hoglund, Kayla Betz, Alison Yu, PhD, Bruce R. Blazar, MD, Steve Carpenter, MD PhD, Olivier Harari, MD PhD, Gavin Thurston, PhD, Ivan Maillard, MD PhD, Leslie Kean, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2027.
https://doi.org/10.1182/blood-2018-99-110030
Published: 2018