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Randolph J. Noelle
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Journal Articles

Repurposing a novel anti-cancer RXR agonist to attenuate murine acute GVHD and maintain graft-versus-leukemia responses

Govindarajan Thangavelu, Chao Wang, Michael Loschi, Asim Saha, Mark J. Osborn, Scott N. Furlan, Kazutoshi Aoyama, Cameron McDonald-Hyman, Ethan G. Aguilar, Amanda S. Janesick, Roshantha A. Chandraratna, Yosef Refaeli, Angela Panoskaltsis-Mortari, Kelli P. MacDonald, Geoffrey R. Hill, Robert Zeiser, Ivan Maillard, Jonathan S. Serody, William J. Murphy, David H. Munn, Bruce Blumberg, Chrysothemis Brown, Vijay Kuchroo, Leslie S. Kean, Keli L. Hippen, Randolph J. Noelle, Bruce R. Blazar
Journal: Blood
Blood (2021) 137 (8): 1090–1103.
https://doi.org/10.1182/blood.2020005628
Published: 2021
Includes: Supplemental data
Journal Articles

Inhibiting retinoic acid signaling ameliorates graft-versus-host disease by modifying T-cell differentiation and intestinal migration

Kazutoshi Aoyama, Asim Saha, Jakub Tolar, Megan J. Riddle, Rachelle G. Veenstra, Patricia A. Taylor, Rune Blomhoff, Angela Panoskaltsis-Mortari, Christopher A. Klebanoff, Gérard Socié, David H. Munn, William J. Murphy, Jonathan S. Serody, LeShara M. Fulton, Takanori Teshima, Roshantha A. Chandraratna, Ethan Dmitrovsky, Yanxia Guo, Randolph J. Noelle, Bruce R. Blazar
Journal: Blood
Blood (2013) 122 (12): 2125–2134.
https://doi.org/10.1182/blood-2012-11-470252
Published: 2013
Includes: Supplemental data
Journal Articles

Platelet CD40L mediates thrombotic and inflammatory processes in atherosclerosis

Dirk Lievens, Alma Zernecke, Tom Seijkens, Oliver Soehnlein, Linda Beckers, Imke C. A. Munnix, Erwin Wijnands, Pieter Goossens, Roger van Kruchten, Larissa Thevissen, Louis Boon, Richard A. Flavell, Randolph J. Noelle, Norbert Gerdes, Erik A. Biessen, Mat J. A. P. Daemen, Johan W. M. Heemskerk, Christian Weber, Esther Lutgens
Journal: Blood
Blood (2010) 116 (20): 4317–4327.
https://doi.org/10.1182/blood-2010-01-261206
Published: 2010
Includes: Supplemental data
Journal Articles

The CD40-TRAF6 axis is the key regulator of the CD40/CD40L system in neointima formation and arterial remodeling

Marjo M. P. C. Donners, Linda Beckers, Dirk Lievens, Imke Munnix, Johan Heemskerk, Ben J. Janssen, Erwin Wijnands, Jack Cleutjens, Alma Zernecke, Christian Weber, Cory L. Ahonen, Ulrike Benbow, Andrew C. Newby, Randolph J. Noelle, Mat J. A. P. Daemen, Esther Lutgens
Journal: Blood
Blood (2008) 111 (9): 4596–4604.
https://doi.org/10.1182/blood-2007-05-088906
Published: 2008
Includes: Supplemental data
Journal Articles

Enhanced efficacy and reduced toxicity of multifactorial adjuvants compared with unitary adjuvants as cancer vaccines

Cory L. Ahonen, Anna Wasiuk, Shinichiro Fuse, Mary Jo Turk, Marc S. Ernstoff, Arief A. Suriawinata, James D. Gorham, Ross M. Kedl, Edward J. Usherwood, Randolph J. Noelle
Journal: Blood
Blood (2008) 111 (6): 3116–3125.
https://doi.org/10.1182/blood-2007-09-114371
Published: 2008
Includes: Supplemental data
Journal Articles

The in vivo function of a noncanonical TRAF2-binding domain in the C-terminus of CD40 in driving B-cell growth and differentiation

Li-Fan Lu, Cory L. Ahonen, Evan F. Lind, Vanitha S. Raman, W. James Cook, Ling-Li Lin, Randolph J. Noelle
Journal: Blood
Blood (2007) 110 (1): 193–200.
https://doi.org/10.1182/blood-2006-07-038414
Published: 2007
Journal Articles

Targeting of inducible costimulator (ICOS) expressed on alloreactive T cells down-regulates graft-versus-host disease (GVHD) and facilitates engraftment of allogeneic bone marrow (BM)

Patricia A. Taylor, Angela Panoskaltsis-Mortari, Gordon J. Freeman, Arlene H. Sharpe, Randolph J. Noelle, Alexander Y. Rudensky, Tak W. Mak, Jonathan S. Serody, Bruce R. Blazar
Journal: Blood
Blood (2005) 105 (8): 3372–3380.
https://doi.org/10.1182/blood-2004-10-3869
Published: 2005
Journal Articles

Mechanisms of donor-specific transfusion tolerance: preemptive induction of clonal T-cell exhaustion via indirect presentation

Sergio A. Quezada, Bruce Fuller, Lamis Z. Jarvinen, Mercedes Gonzalez, Bruce R. Blazar, Alexander Y. Rudensky, Terry B. Strom, Randolph J. Noelle
Journal: Blood
Blood (2003) 102 (5): 1920–1926.
https://doi.org/10.1182/blood-2003-02-0586
Published: 2003
Journal Articles

Combined effects of calcineurin inhibitors or sirolimus with anti-CD40L mAb on alloengraftment under nonmyeloablative conditions

Patricia A. Taylor, Christopher J. Lees, Jessica M. Wilson, Michael J. Ehrhardt, Matthew T. Campbell, Randolph J. Noelle, Bruce R. Blazar
Journal: Blood
Blood (2002) 100 (9): 3400–3407.
https://doi.org/10.1182/blood-2002-03-0872
Published: 2002
Journal Articles

Tolerance induction of alloreactive T cells via ex vivo blockade of the CD40:CD40L costimulatory pathway results in the generation of a potent immune regulatory cell

Patricia A. Taylor, Thea M. Friedman, Robert Korngold, Randolph J. Noelle, Bruce R. Blazar
Journal: Blood
Blood (2002) 99 (12): 4601–4609.
https://doi.org/10.1182/blood.V99.12.4601
Published: 2002
Journal Articles

Requirements for the promotion of allogeneic engraftment by anti-CD154 (anti-CD40L) monoclonal antibody under nonmyeloablative conditions

Patricia A. Taylor, Christopher J. Lees, Herman Waldmann, Randolph J. Noelle, Bruce R. Blazar
Journal: Blood
Blood (2001) 98 (2): 467–474.
https://doi.org/10.1182/blood.V98.2.467
Published: 2001