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Journal Articles

Alloengraftment without significant toxicity or GVHD in CD45 antibody-drug conjugate–conditioned Fanconi anemia mice

Blood (2024) 143 (21): 2201–2216.

https://doi.org/10.1182/blood.2023023549

Published: 2024

Includes: Supplemental data

Journal Articles

Prevention of acute GVHD using an orthogonal IL-2/IL-2Rβ system to selectively expand regulatory T cells in vivo

Blood (2023) 141 (11): 1337–1352.

https://doi.org/10.1182/blood.2022018440

Published: 2023

Includes: Supplemental data

Journal Articles

BET-bromodomain and EZH2 inhibitor–treated chronic GVHD mice have blunted germinal centers with distinct transcriptomes

Blood (2022) 139 (19): 2983–2997.

https://doi.org/10.1182/blood.2021014557

Published: 2022

Includes: Supplemental data

Journal Articles

A CD45-targeted antibody-drug conjugate successfully conditions for allogeneic hematopoietic stem cell transplantation in mice

Asim Saha, Sharon Hyzy, Tahirih Lamothe, Katelyn Hammond, Nicholas Clark, Leanne Lanieri, Prashant Bhattarai, Rahul Palchaudhuri, Geoffrey O. Gillard, Jennifer Proctor, Megan J. Riddle, Angela Panoskaltsis-Mortari, Margaret L. MacMillan, John E. Wagner, Hans-Peter Kiem, Lisa M. Olson, Bruce R. Blazar

Blood (2022) 139 (11): 1743–1759.

https://doi.org/10.1182/blood.2021012366

Published: 2022

Includes: Supplemental data

Journal Articles

Repurposing a novel anti-cancer RXR agonist to attenuate murine acute GVHD and maintain graft-versus-leukemia responses

Blood (2021) 137 (8): 1090–1103.

https://doi.org/10.1182/blood.2020005628

Published: 2021

Includes: Supplemental data

Journal Articles

Single Agent CD45-Targeted Antibody Drug Conjugate Enables Full Mismatch Allogeneic Hematopoietic Stem Cell Transplantation in a Murine HSCT Model

Sharon L. Hyzy, MS, Jennifer L Proctor, BS, Geoff O Gillard, PhD, Katelyn J. Hammond, BS, Ganapathy N. Sarma, PhD, Asim Saha, PhD, Nicholas Clark, PhD, Anjali Bhat, MS, Tahirih L Lamothe, BS, Rahul Palchaudhuri, PhD, Bradley R Pearse, PhD, Charlotte F McDonagh, PhD, Hans-Peter Kiem, MDPhD, John E Wagner, MD, Bruce R. Blazar, MD, Anthony E Boitano, PhD, Michael P Cooke, PhD, John C. Davis, Jr., MD MPH, MS

Blood (2020) 136 (Supplement 1): 31.

https://doi.org/10.1182/blood-2020-140489

Published: 2020

Journal Articles

Danger-associated extracellular ATP counters MDSC therapeutic efficacy in acute GVHD

Blood (2019) 134 (19): 1670–1682.

https://doi.org/10.1182/blood.2019001950

Published: 2019

Journal Articles

In Vitro Induction of Human Regulatory T-Cells (iTregs) Using Conditions of Low Tryptophan Plus Kynurenines

Keli L. Hippen, PhD, Margaret L. MacMillan, MD, Amanda Lemire, BS, Asim Saha, PhD, Eric Hanse, Colin Lord, Ameeta Kelekar, PhD, Roddy S. O'Connor, PhD, James L. Riley, PhD, Carl H June, MD, Leslie Kean, MD PhD, Jeffrey S. Miller, MD, John E. Wagner, MD, David H. Munn, MD, Bruce R. Blazar, MD

Blood (2016) 128 (22): 1229.

https://doi.org/10.1182/blood.V128.22.1229.1229

Published: 2016

Journal Articles

Critical Roles of Retinoic Acid Signaling in Combating Acute Graft Versus Host Disease

Govindarajan Thangavelu, PhD, Asim Saha, PhD, Kazutoshi Aoyama, MD PhD, Cameron McDonald-Hyman, BA, Yu-Chi Lee, MSc, Chrysothemis Brown, MBBS, PhD, Angela Panoskaltsis-Mortari, PhD, Mark J. Osborn, PhD, Roshantha A Chandraratna, PhD, Randolph Noelle, PhD, Bruce R. Blazar, MD

Blood (2016) 128 (22): 4534.

https://doi.org/10.1182/blood.V128.22.4534.4534

Published: 2016

Journal Articles

Protein Kinase C-Theta Interacts with mTORC2 and Vimentin to Limit Regulatory T-Cell Function

Cameron McDonald-Hyman, BA, Govindarajan Thangavelu, PhD, James Muller, Guoan Zhang, PhD, Sudha Kumari, PhD, Asim Saha, PhD, Brent H. Koehn, PhD, Jason S. Mitchell, PhD, Brian T Fife, PhD, Jonathan S. Serody, MD, Mark J. Osborn, PhD, Keli L. Hippen, PhD, Ameeta Kelekar, PhD, David H. Munn, MD, Amnon Altman, PhD, Thomas A. Neubert, PhD, Michael L. Dustin, PhD, Bruce R. Blazar, MD

Blood (2015) 126 (23): 849.

https://doi.org/10.1182/blood.V126.23.849.849

Published: 2015

Journal Articles

Loss of Programmed Death Ligand-1 Expression on Donor T Cells Lessens Acute Graft-Versus-Host Disease Lethality

Blood (2015) 126 (23): 147.

https://doi.org/10.1182/blood.V126.23.147.147

Published: 2015

Journal Articles

Role of PD-1/PD-L1 in Acute and Chronic Graft Versus Host Disease

Bruce R. Blazar, MD, Roddy S. O'Connor, PhD, Michael C. Milone, MD PhD, Michael L. Dustin, PhD, James L. Riley, PhD, Benjamin G. Vincent, MD, Jonathan S. Serody, MD, Ryan P Flynn, PhD, Katelyn Paz, Jing Du, Angela Panoskaltsis-Mortari, PhD, Miller Jeffrey, MD, Rafi Ahmed, PhD, Laurence A. A. Turka, MD, Gordon J. Freeman, PhD, Arlene H. Sharpe, MDPhD, Asim Saha, PhD

Blood (2015) 126 (23): SCI-8.

https://doi.org/10.1182/blood.V126.23.SCI-8.SCI-8

Published: 2015

Journal Articles

B7-H3 expression in donor T cells and host cells negatively regulates acute graft-versus-host disease lethality

Rachelle G. Veenstra, Ryan Flynn, Katharina Kreymborg, Cameron McDonald-Hyman, Asim Saha, Patricia A. Taylor, Mark J. Osborn, Angela Panoskaltsis-Mortari, Annette Schmitt-Graeff, Elisabeth Lieberknecht, William J. Murphy, Jonathan S. Serody, David H. Munn, Gordon J. Freeman, James P. Allison, Tak W. Mak, Marcel van den Brink, Robert Zeiser, Bruce R. Blazar

Blood (2015) 125 (21): 3335–3346.

https://doi.org/10.1182/blood-2014-09-603357

Published: 2015

Includes: Supplemental data

Journal Articles

Host programmed death ligand 1 is dominant over programmed death ligand 2 expression in regulating graft-versus-host disease lethality

Asim Saha, Kazutoshi Aoyama, Patricia A. Taylor, Brent H. Koehn, Rachelle G. Veenstra, Angela Panoskaltsis-Mortari, David H. Munn, William J. Murphy, Miyuki Azuma, Hideo Yagita, Brian T. Fife, Mohammed H. Sayegh, Nader Najafian, Gerard Socie, Rafi Ahmed, Gordon J. Freeman, Arlene H. Sharpe, Bruce R. Blazar

Blood (2013) 122 (17): 3062–3073.

https://doi.org/10.1182/blood-2013-05-500801

Published: 2013

Includes: Supplemental data

Journal Articles

Inhibiting retinoic acid signaling ameliorates graft-versus-host disease by modifying T-cell differentiation and intestinal migration

Blood (2013) 122 (12): 2125–2134.

https://doi.org/10.1182/blood-2012-11-470252

Published: 2013

Includes: Supplemental data

NARROW

Alloengraftment without significant toxicity or GVHD in CD45 antibody-drug conjugate–conditioned Fanconi anemia mice

Prevention of acute GVHD using an orthogonal IL-2/IL-2Rβ system to selectively expand regulatory T cells in vivo

BET-bromodomain and EZH2 inhibitor–treated chronic GVHD mice have blunted germinal centers with distinct transcriptomes

A CD45-targeted antibody-drug conjugate successfully conditions for allogeneic hematopoietic stem cell transplantation in mice

Repurposing a novel anti-cancer RXR agonist to attenuate murine acute GVHD and maintain graft-versus-leukemia responses

Single Agent CD45-Targeted Antibody Drug Conjugate Enables Full Mismatch Allogeneic Hematopoietic Stem Cell Transplantation in a Murine HSCT Model

Danger-associated extracellular ATP counters MDSC therapeutic efficacy in acute GVHD

In Vitro Induction of Human Regulatory T-Cells (iTregs) Using Conditions of Low Tryptophan Plus Kynurenines

Critical Roles of Retinoic Acid Signaling in Combating Acute Graft Versus Host Disease

Protein Kinase C-Theta Interacts with mTORC2 and Vimentin to Limit Regulatory T-Cell Function

Loss of Programmed Death Ligand-1 Expression on Donor T Cells Lessens Acute Graft-Versus-Host Disease Lethality

Role of PD-1/PD-L1 in Acute and Chronic Graft Versus Host Disease

B7-H3 expression in donor T cells and host cells negatively regulates acute graft-versus-host disease lethality

Host programmed death ligand 1 is dominant over programmed death ligand 2 expression in regulating graft-versus-host disease lethality

Inhibiting retinoic acid signaling ameliorates graft-versus-host disease by modifying T-cell differentiation and intestinal migration

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American Society of Hematology

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ASH Publications

American Society of Hematology

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