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Journal Articles

BET-bromodomain and EZH2 inhibitor–treated chronic GVHD mice have blunted germinal centers with distinct transcriptomes

Blood (2022) 139 (19): 2983–2997.

https://doi.org/10.1182/blood.2021014557

Published: 2022

Includes: Supplemental data

Journal Articles

Small-molecule BCL6 inhibitor effectively treats mice with nonsclerodermatous chronic graft-versus-host disease

Blood (2019) 133 (1): 94–99.

https://doi.org/10.1182/blood-2018-03-839993

Published: 2019

Journal Articles

Biology of PD-1 Checkpoint Blockade

Arlene H. Sharpe, MD PhD

Blood (2017) 130 (Supplement 1): SCI-35.

https://doi.org/10.1182/blood.V130.Suppl_1.SCI-35.SCI-35

Published: 2017

Journal Articles

Loss of Programmed Death Ligand-1 Expression on Donor T Cells Lessens Acute Graft-Versus-Host Disease Lethality

Blood (2015) 126 (23): 147.

https://doi.org/10.1182/blood.V126.23.147.147

Published: 2015

Journal Articles

Role of PD-1/PD-L1 in Acute and Chronic Graft Versus Host Disease

Bruce R. Blazar, MD, Roddy S. O'Connor, PhD, Michael C. Milone, MD PhD, Michael L. Dustin, PhD, James L. Riley, PhD, Benjamin G. Vincent, MD, Jonathan S. Serody, MD, Ryan P Flynn, PhD, Katelyn Paz, Jing Du, Angela Panoskaltsis-Mortari, PhD, Miller Jeffrey, MD, Rafi Ahmed, PhD, Laurence A. A. Turka, MD, Gordon J. Freeman, PhD, Arlene H. Sharpe, MDPhD, Asim Saha, PhD

Blood (2015) 126 (23): SCI-8.

https://doi.org/10.1182/blood.V126.23.SCI-8.SCI-8

Published: 2015

Journal Articles

Host programmed death ligand 1 is dominant over programmed death ligand 2 expression in regulating graft-versus-host disease lethality

Asim Saha, Kazutoshi Aoyama, Patricia A. Taylor, Brent H. Koehn, Rachelle G. Veenstra, Angela Panoskaltsis-Mortari, David H. Munn, William J. Murphy, Miyuki Azuma, Hideo Yagita, Brian T. Fife, Mohammed H. Sayegh, Nader Najafian, Gerard Socie, Rafi Ahmed, Gordon J. Freeman, Arlene H. Sharpe, Bruce R. Blazar

Blood (2013) 122 (17): 3062–3073.

https://doi.org/10.1182/blood-2013-05-500801

Published: 2013

Includes: Supplemental data

Journal Articles

Program death-1 signaling and regulatory T cells collaborate to resist the function of adoptively transferred cytotoxic T lymphocytes in advanced acute myeloid leukemia

Qing Zhou, Meghan E. Munger, Steven L. Highfill, Jakub Tolar, Brenda J. Weigel, Megan Riddle, Arlene H. Sharpe, Daniel A. Vallera, Miyuki Azuma, Bruce L. Levine, Carl H. June, William J. Murphy, David H. Munn, Bruce R. Blazar

Blood (2010) 116 (14): 2484–2493.

https://doi.org/10.1182/blood-2010-03-275446

Published: 2010

Includes: Supplemental data

Journal Articles

TLR agonists regulate alloresponses and uncover a critical role for donor APCs in allogeneic bone marrow rejection

Patricia A. Taylor, Michael J. Ehrhardt, Christopher J. Lees, Angela Panoskaltsis-Mortari, Arthur M. Krieg, Arlene H. Sharpe, William J. Murphy, Jonathan S. Serody, Hiroaki Hemmi, Shizuo Akira, Robert B. Levy, Bruce R. Blazar

Blood (2008) 112 (8): 3508–3516.

https://doi.org/10.1182/blood-2007-09-113670

Published: 2008

Journal Articles

Requirement of homotypic NK-cell interactions through 2B4(CD244)/CD48 in the generation of NK effector functions

Kyung-Mi Lee, John P. Forman, Megan E. McNerney, Susan Stepp, Sumalatha Kuppireddi, Dustin Guzior, Yvette E. Latchman, Mohamed H. Sayegh, Hideo Yagita, Chul-Kyu Park, Seog Bae Oh, Christoph Wülfing, John Schatzle, Porunelloor A. Mathew, Arlene H. Sharpe, Vinay Kumar

Blood (2006) 107 (8): 3181–3188.

https://doi.org/10.1182/blood-2005-01-0185

Published: 2006

Journal Articles

Targeting of inducible costimulator (ICOS) expressed on alloreactive T cells down-regulates graft-versus-host disease (GVHD) and facilitates engraftment of allogeneic bone marrow (BM)

Patricia A. Taylor, Angela Panoskaltsis-Mortari, Gordon J. Freeman, Arlene H. Sharpe, Randolph J. Noelle, Alexander Y. Rudensky, Tak W. Mak, Jonathan S. Serody, Bruce R. Blazar

Blood (2005) 105 (8): 3372–3380.

https://doi.org/10.1182/blood-2004-10-3869

Published: 2005

Journal Articles

Rap1-GTP Promotes the Generation of Regulatory T Cells in Vivo.

Lequn Li, MD, PhD, Rebecca Greenwald, PhD, Esther M. Lafuente, PhD, Dimitrios Tzachanis, MD, PhD, Alla Berezovskaya, Gordon J. Freeman, PhD, Arlene H. Sharpe, MD, PhD, Vassiliki A. Boussiotis, MD, PhD

Blood (2004) 104 (11): 110.

https://doi.org/10.1182/blood.V104.11.110.110

Published: 2004

Journal Articles

Ligation of OX40 (CD134) regulates graft-versus-host disease (GVHD) and graft rejection in allogeneic bone marrow transplant recipients

Bruce R. Blazar, Arlene H. Sharpe, Andy I. Chen, Angela Panoskaltsis-Mortari, Christopher Lees, Hisaya Akiba, Hideo Yagita, Nigel Killeen, Patricia A. Taylor

Blood (2003) 101 (9): 3741–3748.

https://doi.org/10.1182/blood-2002-10-3048

Published: 2003

Journal Articles

Prevention and treatment of factor VIII inhibitors in murine hemophilia A

Jiahua Qian, Mary Collins, Arlene H. Sharpe, Leon W. Hoyer

Blood (2000) 95 (4): 1324–1329.

https://doi.org/10.1182/blood.V95.4.1324.004k25_1324_1329

Published: 2000

NARROW

BET-bromodomain and EZH2 inhibitor–treated chronic GVHD mice have blunted germinal centers with distinct transcriptomes

Small-molecule BCL6 inhibitor effectively treats mice with nonsclerodermatous chronic graft-versus-host disease

Biology of PD-1 Checkpoint Blockade

Loss of Programmed Death Ligand-1 Expression on Donor T Cells Lessens Acute Graft-Versus-Host Disease Lethality

Role of PD-1/PD-L1 in Acute and Chronic Graft Versus Host Disease

Host programmed death ligand 1 is dominant over programmed death ligand 2 expression in regulating graft-versus-host disease lethality

Program death-1 signaling and regulatory T cells collaborate to resist the function of adoptively transferred cytotoxic T lymphocytes in advanced acute myeloid leukemia

TLR agonists regulate alloresponses and uncover a critical role for donor APCs in allogeneic bone marrow rejection

Requirement of homotypic NK-cell interactions through 2B4(CD244)/CD48 in the generation of NK effector functions

Targeting of inducible costimulator (ICOS) expressed on alloreactive T cells down-regulates graft-versus-host disease (GVHD) and facilitates engraftment of allogeneic bone marrow (BM)

Rap1-GTP Promotes the Generation of Regulatory T Cells in Vivo.

Ligation of OX40 (CD134) regulates graft-versus-host disease (GVHD) and graft rejection in allogeneic bone marrow transplant recipients

Prevention and treatment of factor VIII inhibitors in murine hemophilia A

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American Society of Hematology

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ASH Publications

American Society of Hematology

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